Department of Chemestry
| Search: Chemistry Dep. / all Hamburg | |
| 2025 | |
| 354 |
IncobotulinumtoxinA in the Treatment of Upper Facial Lines: Results From Two Randomized, Double-Blind, Placebo-Controlled, Phase III Studies John Joseph, Vladimir Sudimac, Sabine Mersmann, Martina Kerscher Aesthetic Surgery Journal 45, 293304 (2025) |
| 353 |
Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma Jan-Malte Placke, Jenny Bottek, Renata Váraljai, Batool Shannan, Sarah Scharfenberg, Christoph Krisp, Philippa Spangenberg, Camille Soun, Devon Siemes, Lars Borgards, Franziska Hoffmann, Fang Zhao, Anette Paschen, Hartmut Schlüter , Ferdinand von Eggeling, Iris Helfrich, Florian Rambow, Selma Ugurel, Alpaslan Tasdogan, Dirk Schadendorf, Daniel R. Engel, Alexander Roesch British Journal of Dermatology 192, 481-491 (2025) |
| 352 |
Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum Vojtech Pražák, Daven Vasishtan, Kay Grünewald , Ross G. Douglas, Josie L Ferreira EMBO Reports online: 24 March 2025 (2025) |
| 351 |
A universal DNA microarray for rapid fish species authentication Patrizia Bade, Sebastian Stix, Kristina Kappel, Jan Fritsche , Ilka Haase, Andrew E. Torda , Nils Wax, Markus Fischer , Dirk Brandis, Ute Schröder Food Chemistry: Molecular Sciences 10, 100241 (11 pp) (2025) |
| 350 |
Unveiling the cell biology of hippocampal neurons with dendritic axon origin Yuhao Han, Daniela Hacker, Bronte Catharina Donders, Christopher Parperis, Roland Thuenauer, Christophe Leterrier, Kay Grünewald , Marina Mikhaylova Journal of Cell Biology 224, e202403141 (33 pp) (2025) |
| 349 |
Structure of Protein Cage Supercrystals Revealed by Angular X-ray Cross-Correlation Analysis Kuan Hoon Ngoi, Laurin Lang, Young Yong Kim, Niklas Mucke, Gerard N. Hinsley, Dongwon Kim, Michael Rütten, Lars Klemeyer , Maximilian Ruffer, Varnika Yadav, Henrike Wagler, Tobias Katenkamp, Markus Perbandt , Azat Khadiev, Dmitri Novikov, Tobias Beck , Ivan A. Vartanyants Small Structures online: 06 April 2025 (2025) |
2024 | |
| 348 |
Assembly of Differently Sized Supercharged Protein Nanocages into Superlattices for Construction of Binary Nanoparticle-Protein Materials Michael Rütten, Laurin Lang, Henrike Wagler, Marcel Lach, Niklas Mucke, Ulrike Laugks, Carolin Seuring , Thomas F. Keller, Andreas Stierle , Helen M. Ginn, Tobias Beck ACS Nano 18, 25325-25336 (2024) |
| 347 |
Comparative Study of Physicochemical Properties and Antibacterial Potential of Cyanobacteria Spirulina platensis-Derived and Chemically Synthesized Silver Nanoparticles Ani Harutyunyan, Liana Gabrielyan, Anush Aghajanyan, Susanna Gevorgyan, Robin Schubert, Christian Betzel , Wojciech Kujawski, Lilit Gabrielyan ACS Omega 9, 29410-29421 (2024) |
| 346 |
nQuant Enables Precise Quantitative N-Glycomics Yudong Guan, Shanshan Zhao, Chunjin Fu, Junzhe Zhang, Fan Yang, Jiankai Luo, Lingyun Dai, Xihai Li, Hartmut Schlüter , Jigang Wang, Chengchao Xu Analytical Chemistry 96, 15531-15539 (2024) |
| 345 |
Synthesis and antibacterial properties under blue LED light of conjugates between the siderophore desferrioxamine B (DFOB) and an Iridium(III) complex Aline Faucon, Julien Renault, Inokentijs Josts, Julie Couchot, Jean-Luc Renaud, Françoise Hoegy, Patrick Plésiat, Henning Tidow , Sylvain Gaillard, Gaëtan L. A. Mislin Bioorganic & Medicinal Chemistry 112, 117842 (10 pp) (2024) |
| 344 |
Automated high-throughput selection of DNA aptamers using a common optical next-generation sequencer Alissa Drees , Christian Ahlers, Timothy Kehrer, Natascha Ehmke, Alice Frederike Rosa Grün, Charlotte Uetrecht, Zoya Ignatova , Udo Schumacher, Markus Fischer bioRxiv 2024.06.24.600375, 43 pp (2024) |
| 343 |
Visualizing how antibiotics interact with ribosomes Helge Paternoga , Daniel N. Wilson BIOspektrum 30, 158-161 (2024) |
| 342 |
The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System Fabian Bernhard Pallasch, Vera Freytag, Malte Kriegs, Dennis Gatzemeier, Thomas Mair, Hannah Voß, Kristoffer Riecken, Mona Dawood, Boris Fehse, Thomas Efferth, Hartmut Schlüter , Udo Schumacher Cancers 16, 2278 (22 pp) (2024) |
| 341 |
Cellular Importin-a3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection Swantje Thiele, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Martin Zickler, Martin Müller, Berfin Tuku, Patricia Resa-Infante, Debby van Riel, Malik Alawi, Thomas Günther, Franziska Rother, Stefanie Hügel, Susanne Reimering, Alice McHardy, Adam Grundhoff , Wolfram Brune , Albert Osterhaus, Michael Bader, Enno Hartmann, Gülsah Gabriel Cell Reports 31, 107549 (23 pp) (2024) |
| 340 |
A simple method for rapid cloning of complete herpesvirus genomes Jan Knickmann, Laura Staliunaite, Olha Puhach, Eleonore Ostermann, Thomas Günther, Jenna Nichols, Michael A. Jarvis, Sebastian Voigt, Adam Grundhoff , Andrew J. Davison, Wolfram Brune Cell Reports Methods 4, 100696 (17 pp) (2024) |
| 339 |
Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo Yuqi Gui, Yohan Kim, Santra Brenna, Maximilian Wilmes, Giorgio Zaghen, Chris N. Goulbourne, Lennart Kuchenbecker-Pöls, Bente Siebels, Hannah Voß, Antonia Gocke, Hartmut Schlüter , Michaela Schweizer, Hermann C. Altmeppen, Tim Magnus, Efrat Levy, Berta Puig Cellular and Molecular Life Sciences 81, 224 (20 pp) (2024) |
| 338 |
Assay for Characterizing Adsorption-Properties of Surfaces (APS) Bente Siebels, Manuela Moritz, Diana Hübler, Antonia Gocke, Maria Riedner , Hannah Voß, Hartmut Schlüter Chemistry - A European Journal 30, e202403000 (9 pp) (2024) |
| 337 |
Chronic Activation of Tubulin Tyrosination Improves Heart Function Niels Pietsch, Christina Y. Chen, Svenja Kupsch, Lucas Bacmeister, Birgit Geertz, Marisol Herrera-Rivero, Bente Siebels, Hannah Voß, Elisabeth Krämer, Ingke Braren, Dirk Westermann, Hartmut Schlüter , Giulia Mearini, Saskia Schlossarek, Jolanda van der Velden, Matthew A. Caporizzo, Diana Lindner, Benjamin L. Prosser, Lucie Carrier Circulation Research 135, 910-932 (2024) |
| 336 |
Time-resolved crystallography of boric acid binding to the active site serine of the β-lactamase CTX-M-14 and subsequent 1,2-diol esterification Andreas Prester, Markus Perbandt , Marina Galchenkova, Dominik Oberthür , Nadine Werner, Alessandra Henkel, Julia Maracke, Oleksandr Yefanov, Johanna Hakanpää, Guillaume Pompidor, Jan Meyer, Henry Chapman, Martin Aepfelbacher , Winfried Hinrichs, Holger Rohde , Christian Betzel Communications Chemistry 7, 152 (12 pp) (2024) |
| 335 |
2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca2+ concentrations Jelena Pick, Simon Sander, Stefanie Etzold, Anette Rosche, Henning Tidow , Andreas H. Guse , Ralf Fliegert Frontiers in Immunology 15, 1294357 (11 pp) (2024) |
| 334 |
16S rRNA sequencing analysis of the oral and fecal microbiota in colorectal cancer positives versus colorectal cancer negatives in Iranian population Sama Rezasoltani, Mehdi Azizmohammad Looha, Hamid Asadzadeh Aghdaei, Seyedesomayeh Jasemi, Leonardo Antonio Sechi, Maria Gazouli, Amir Sadeghi, Shirin Torkashvand, Reyhaneh Baniali, Hartmut Schlüter , Mohammad Reza Zali, Mohammad Mehdi Feizabadi Gut Pathogens 16, 9 (2024) Erratum: Gut Pathogens 16, 15 (2024) |
| 333 |
Growing a single suspended perfect protein crystal in a fully noncontact manner Zi-Qing Wu, Yong-Ming Liu, Qing-di Cheng, Chen-Yuan Li, Ya-Li Liu, Wan-Yi Ge, Sven Falke, Hévila Brognaro, Jing-Jie Chen, Huan Zhou, Peng Shang, Jian-Hua He, Christian Betzel , Da-Chuan Yin International Journal of Biological Macromolecules 282, 136637 (10 pp) (2024) |
| 332 |
Different Forms of TFF3 in the Human Endocervix, including a Complex with IgG Fc Binding Protein (FCGBP), and Further Aspects of the Cervico-Vaginal Innate Immune Barrier Aikaterini Laskou, Eva B. Znalesniak, Sönke Harder, Hartmut Schlüter , Dörthe Jechorek, Kathrin Langer, Carina Strecker, Claudia Matthes, Svetlana N. Tchaikovski, Werner Hoffmann International Journal of Molecular Sciences 25, 2287 (21 pp) (2024) |
| 331 |
Hypoxia-Induced Adaptations of N-Glycomes and Proteomes in Breast Cancer Cells and Their Secreted Extracellular Vesicles Bojia Peng, Kai Bartkowiak, Feizhi Song, Paula Nissen, Hartmut Schlüter , Bente Siebels International Journal of Molecular Sciences 25, 10216 (16 pp) (2024) |
| 330 |
Novel Catechol O-methyltransferases from Lentinula edodes Catalyze the Generation of Taste-Active Flavonoids Jean-Philippe Kanter, Lars Milke, Judith K. Metz, Ali Biabani, Hartmut Schlüter , Martin Gand, Jakob P. Ley, Holger Zorn Journal of Agricultural and Food Chemistry 72, 11002-11012 (2024) |
| 329 |
Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface Angélica Luana C. Barra, Najeeb Ullah, Hévila Brognaro, Raissa F. Gutierrez, Carsten Wrenger, Christian Betzel , Alessandro S. Nascimento Journal of Biological Chemistry 300, 107404 (2024) |
| 328 |
Proximity labeling of host factor ANXA3 in HCV infection reveals a novel LARP1 function in viral entry Hanna Bley, Christoph Krisp, Anja Schöbel, Julia Hehner, Laura Schneider, Miriam Becker, Cora Stegmann, Elisa Heidenfels, Van Nguyen-Dinh, Hartmut Schlüter , Gisa Gerold, Eva Herker Journal of Biological Chemistry 300, 5107286 (18 pp) (2024) |
| 327 |
Validation of a Photonumeric Scale for Evaluation of Telangiectasia in Rosacea Lynhda Nguyen, Nikolaus Seeber, Jens M. Baron, Stefan Hammes, Syrus Karsai, Tanja C. Fischer, Laurence Imhof, Gerd Kautz, Sonja Sattler, Maximilian Deussing, Cathy Dierckxsens, Alexander Thiem, Zacharias Drosos, Stephan Grosse-Buening, Nomun Ganjuur, Anna-Sophie Kampmann, Johanna K. May, Stefan W. Schneider , Martina Kerscher, Katharina Herberger Journal of Cosmetic Dermatology online: 27 October 2024 (2024) |
| 326 |
Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser-A prospective, controlled study Lynhda Nguyen, Cathy Dierckxsens, Martina Kerscher, Anna Hartjen, Stefan W. Schneider , Katharina Herberger Journal of Cosmetic Dermatology 23, 2443-2449 (2024) |
| 325 |
AI assistance in aesthetic medicine-A consensus on objective medical standards Konstantin Frank, Doris Day, Julius Few, Chhabra Chiranjiv, Michael Gold, Sonja Sattler, Martina Kerscher, Leonard Knoedler, Alexandre Filippo, Berthold Rzany, Sebastian Cotofana, Sabrina Fabi, Klaus Fritz, Peter Peng, Rungsima Wanitphakdeedecha, Rainer Pooth, Patrick Huang Journal of Cosmetic Dermatology 23, 4110-4115 (2024) |
| 324 |
A Prospective, Multicenter, Evaluator-Blinded, Randomized Study of Diluted Calcium Hydroxylapatite to Treat Decollete Wrinkles Tatjana Pavicic, Martina Kerscher, Ulrich Kuhne, Iryna Heide, Hanna Dersch, Gemma Odena, Virginia Graul Journal of Drugs in Dermatology 23, 551-556 (2024) |
| 323 |
International Consensus on Anti-Aging Dermocosmetics and Skin Care for Clinical Practice Using the RAND/UCLA Appropriateness Method Zoe D. Draelos, Liu Wei, Mukta Sachdev, Bruna S. F. Bravo, Vasanop Vachiramon, Marie Jourdan, Martina Kerscher, Catherine Delva, Stephanie Leclerc-Mercier Journal of Drugs in Dermatology 23, 1337 (7 pp) (2024) |
| 322 |
Objective Facial Assessment With Artificial Intelligence: Introducing the Facial Aesthetic Index and Facial Youthfulness Index Sonja Sattler, Konstantin Frank, Martina Kerscher, Sebastian Cotofana, Tatjana Pavicic, Berthold Rzany, Peter Peng, Rainer Pooth Journal of Drugs in Dermatology 23, e52 (3 pp) (2024) |
| 321 |
HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis Svenja Schneegans, Jana Löptien, Angelika Mojzisch, Desirée Loreth, Oliver Kretz, Christoph Raschdorf, Annkathrin Hanssen, Antonia Gocke, Bente Siebels, Karthikeyan Gunasekaran, Yi Ding, Leticia Oliveira-Ferrer, Laura Brylka, Thorsten Schinke , Hartmut Schlüter , Ilkka Paatero, Hannah Voß, Stefan Werner, Klaus Pantel, Harriet Wikman Journal of Experimental & Clinical Cancer Research 43, 110 (18 pp) (2024) |
| 320 |
Controlling the size, shape, and stability of SeNPs by bromelain: Improved antioxidant, anti-bacterial and anti-cancer activities Surriya Bibi, Aisha Munawar, Muhammad Waqas Ishaq, Fakhar Zaman, Muhammad Abid, Ali Rafi, Ahsan Saeed, Ahmad Akrem, Robin Schubert, Usman Aftab, Syed Abid Ali, Christian Betzel , Irfan Ullah Khan Journal of Molecular Structure 1295, 136633 (11 pp) (2024) |
| 319 |
E2F3-dependent
activation of FAM111B restricts mouse cytomegalovirus replication in primate cells Eleonore Ostermann, Laura-Marie Luoto, Michaela Clausen, Sanamjeet Virdi, Wolfram Brune Journal of Virology 98, 19 pp (2024) |
| 318 |
Human cytomegalovirus glycoprotein variants governing viral tropism and syncytium formation in epithelial cells and macrophages Giorgia Cimato, Xuan Zhou, Wolfram Brune , Giada Frascaroli Journal of Virology 98, e00293-24 (20 pp) (2024) (Editor's Pick) |
| 317 |
Modeling Flexible Protein Structure With AlphaFold2 and Crosslinking Mass Spectrometry Karen Manalastas-Cantos, Kish R. Adoni, Matthias Pfeifer, Birgit Märtens, Kay Grünewald , Konstantinos Thalassinos, Maya Topf Molecular & Cellular Proteomics 23, 100724 (15 pp) (2024) |
| 316 |
N6-methyladenosine in 5'-UTR does not promote translation initiation Ewelina Guca, Rodrigo Alarcon, Michael Z. Palo, Leonardo Santos, Santiago Alonso-Gil, Marcos Davyt, Leonardo H. F. de Lima, Fanny Boissier, Sarada Das, Bojan Zagrovic, Joseph D. Puglisi, Yaser Hashem , Zoya Ignatova Molecular Cell 84, 584-595 (2024) |
| 315 |
Peptidyl-tRNA hydrolase is the nascent chain release factor in bacterial ribosome-associated quality control Maxim S. Svetlov, Clémence F. Dunand, Jose A. Nakamoto, Gemma C. Atkinson, Haaris A. Safdari, Daniel N. Wilson , Nora Vázquez-Laslop, Alexander S. Mankin Molecular Cell 84, 715-726 (2024) |
| 314 |
Structural basis of ribosomal 30S subunit degradation by RNase R Lyudmila Dimitrova-Paternoga, Sergo Kasvandik, Bertrand Beckert, Sander Granneman, Tanel Tenson, Daniel N. Wilson , Helge Paternoga Nature 626, 1133-1140 (2024) |
| 313 |
Paenilamicins are context-specific translocation inhibitors of protein synthesis Timm O. Koller , Max J. Berger, Martino Morici, Helge Paternoga , Timur Bulatov, Adriana di Stasi, Tam Dang, Andi Mainz, Karoline Raulf, Caillan Crowe-McAuliffe, Marco Scocchi, Mario Mardirossian, Bertrand Beckert, Nora Vázquez-Laslop, Alexander S. Mankin, Roderich D. Süssmuth, Daniel N. Wilson Nature Chemical Biology 20, 1691-1700 (2024) |
| 312 |
A cytomegalovirus inflammasome inhibitor reduces proinflammatory cytokine release and pyroptosis Yingqi Deng, Eleonore Ostermann, Wolfram Brune Nature Communications 15, 786 (13 pp) (2024) |
| 311 |
The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome Felix Gersteuer, Martino Morici, Sara Gabrielli, Keigo Fujiwara, Haaris A. Safdari, Helge Paternoga , Lars V. Bock, Shinobu Chiba, Daniel N. Wilson Nature Communications 15, 2431 (16 pp) (2024) Erratum: Nature Communications 15, 3276 (2024) |
| 310 |
RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity Martino Morici, Sara Gabrielli, Keigo Fujiwara, Helge Paternoga , Bertrand Beckert, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson Nature Communications 15, 2432 (16 pp) (2024) Erratum: Nature Communications 15, 3242 (2024) |
| 309 |
Translation velocity determines the efficacy of engineered suppressor tRNAs on pathogenic nonsense mutations Nikhil Bharti, Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jimenez-Sanchez, Jeong S. Hong, Andras Rab, Eric J. Sorscher, Suki Albers , Zoya Ignatova Nature Communications 15, 2957 (2024) |
| 308 |
SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds Patrick Y. A. Reinke, Robin Schubert, Dominik Oberthür , Marina Galchenkova, Aida Rahmani Mashhour, Sebastian Günther, Anaïs Chretien, Adam Round, Brandon Charles Seychell, Brenna Norton-Baker, Chan Kim, Christina Schmidt, Faisal H. M. Koua, Aleksandra Tolstikova , Wiebke Ewert, Gisel Esperanza Peña Murillo, Grant Mills, Henry Kirkwood, Hévila Brognaro, Huijong Han, Jayanath Koliyadu, Joachim Schulz, Johan Bielecki, Julia Lieske, Julia Maracke, Juraj Knoška, Kristina Lorenzen, Lea Brings, Marcin Sikorski, Marco Kloos, Mohammad Vakili, Patrik Vagovic, Philipp Middendorf, Raphael de Wijn, Richard Bean, Romain Letrun, Seonghyun Han, Sven Falke, Tian Geng, Tokushi Sato, Vasundara Srinivasan, Yoonhee Kim, Oleksandr M. Yefanov, Luca Gelisio, Tobias Beck , Andrew S. Doré, Adrian P. Mancuso, Christian Betzel , Saša Bajt, Lars Redecke , Henry N. Chapman , Alke Meents , Dusan Turk, Winfried Hinrichs, Thomas J. Lane Nature Communications 15, 3827 (2024) |
| 307 |
Proteomic analysis of the urothelial cancer landscape Franz F. Dressler, Falk Diedrichs, Deema Sabtan, Sofie Hinrichs, Christoph Krisp, Timo Gemoll, Martin Hennig, Paulina Mackedanz, Mareile Schlotfeldt, Hannah Voß, Anne Offermann, Jutta Kirfel, Marie C. Roesch, Julian P. Struck, Mario W. Kramer, Axel S. Merseburger, Christian Gratzke, Dominik S. Schoeb, Arkadiusz Miernik, Hartmut Schlüter , Ulrich Wetterauer, Roman Zubarev, Sven Perner, Philipp Wolf, Ákos Végvári Nature Communications 15, 4513 (19 pp) (2024) |
| 306 |
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level Shweta Godbole, Hannah Voß, Antonia Gocke, Simon Schlumbohm, Yannis Schumann, Bojia Peng, Martin Mynarek, Stefan Rutkowski, Matthias Dottermusch, Mario M. Dorostkar, Andrey Korshunov, Thomas Mair, Stefan M. Pfister, Marcel Kwiatkowski, Madlen Hotze, Philipp Neumann, Christian Hartmann, Joachim Weis, Friederike Liesche-Starnecker, Yudong Guan, Manuela Moritz, Bente Siebels, Nina Struve, Hartmut Schlüter , Ulrich Schüller, Christoph Krisp, Julia E. Neumann Nature Communications 15, 6237 (24 pp) (2024) |
| 305 |
Infection-induced peripheral mitochondria fission drives ER encapsulations and inter-mitochondria contacts that rescue bioenergetics William A. Hofstadter, Katelyn C. Cook, Elene Tsopurashvili, Robert Gebauer, Vojtech Pražák, Emily A. Machala, Ji Woo Park, Kay Grünewald , Emmanuelle R. J. Quemin, Ileana M. Cristea Nature Communications 15, 7352 (24 pp) (2024) |
| 304 |
Molecular plasticity of herpesvirus nuclear egress analysed in situ Vojtech Pražák, Yuliia Mironova, Daven Vasishtan, Christoph Hagen, Ulrike Laugks, Yannick Jensen, Saskia Sanders, John M. Heumann, Jens B. Bosse, Barbara G. Klupp, Thomas C. Mettenleiter, Michael Grange, Kay Grünewald Nature Microbiology 9, 1842-1855 (2024) |
| 303 |
tRNA therapeutics for genetic diseases Jeff Coller, Zoya Ignatova Nature Reviews Drug Discovery 23, 108-125 (2024) |
| 302 |
The palisade layer of the poxvirus core is composed of flexible A10 trimers Jiasui Liu, Simon Corroyer-Dulmont, Vojtech Pražák, Iskander Khusainov, Karola Bahrami, Sonja Welsch, Daven Vasishtan, Agnieszka Obarska-Kosinska, Sigurdur R. Thorkelsson, Kay Grünewald , Emmanuelle R. J. Quemin, Beata Turonová, Jacomina Krijnse Locker Nature Structural & Molecular Biology 31, 1105-1113 (2024) |
| 301 |
Integrated proteomics spotlight the proteasome as a therapeutic vulnerability in embryonal tumors with multilayered rosettes Matthias Dottermusch, Ali Biabani, Tasja Lempertz, Yannis Schumann, Jelena Navolic, Shweta Godbole, Denise Obrecht, Stephan Frank, Mario M. Dorostkar, Hannah Voß, Hartmut Schlüter , Stefan Rutkowski, Ulrich Schüller, Julia E. Neumann Neuro-Oncology 26, 935-949 (2024) |
| 300 |
Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes Robert Rauscher, Cristian Eggers, Lyudmila Dimitrova-Paternoga, Vaishnavi Shankar, Alessia Rosina, Marina Cristodero, Helge Paternoga , Daniel N. Wilson , Sebastian A. Leidel, Norbert Polacek Nucleic Acids Research 52, 4021-4036 (2024) |
| 299 |
Structural snapshots of phenuivirus cap-snatching and transcription Harry M. Williams, Sigurdur R. Thorkelsson, Dominik Vogel, Carola Busch, Morlin Milewski, Stephen Cusack, Kay Grünewald , Emmanuelle R. J. Quemin, Maria Rosenthal Nucleic Acids Research 52, 6049-6065 (2024) |
| 298 |
Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM Emil Gustavsson, Kay Grünewald , Per Elias, B Martin Hällberg Nucleic Acids Research 52, 7292-7304 (2024) |
| 297 |
A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis Hiraku Takada, Helge Paternoga , Keigo Fujiwara, Jose A. Nakamoto, Esther N. Park, Lyudmila Dimitrova-Paternoga, Bertrand Beckert, Merilin Saarma, Tanel Tenson, Allen R. Buskirk, Gemma C. Atkinson, Shinobu Chiba, Daniel N. Wilson , Vasili Hauryliuk Nucleic Acids Research 52, 8483-8499 (2024) Reprint: bioRxiv 2024.03.03.583159 (2024) |
| 296 |
The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site Kathryn J. Turnbull , Helge Paternoga , Esther von der Weth, Artyom A. Egorov, Agnieszka A. Pochopien, Yujie Zhang, Lilit Nersisyan, Tõnu Margus, Marcus J. O. Johansson, Vicent Pelechano, Daniel N. Wilson , Vasili Hauryliuk Nucleic Acids Research 52, 12005-12020 (2024) |
| 295 |
Differentiable partition function calculation for RNA Marco C. Matthies, Ryan Krueger, Andrew E. Torda , Max Ward Nucleic Acids Research 52, e14 (9 pp) (2024) |
| 294 |
Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells Stefan Ebert, Verena Böhm, Julia K. Büttner, Wolfram Brune , Melanie M. Brinkmann, Rafaela Holtappels, Matthias J. Reddehase, Niels A. W. Lemmermann PLoS Pathogens 20, e1012173 (25 pp) (2024) |
| 293 |
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa Jonas Krueger, Matthias Preusse, Nicolas Oswaldo Gomez, Yannick Noah Frommeyer, Sebastian Doberenz, Anne Lorenz, Adrian Kordes, Svenja Grobe, Mathias Müsken, Daniel P. Depledge, Sarah L. Svensson, Siegfried Weiss, Volkhard Kaever, Andreas Pich, Cynthia M. Sharma, Zoya Ignatova , Susanne Häussler Proceedings of the National Academy of Sciences of the United States of America 121, e2312874121 (12 pp) (2024) |
| 292 |
Guest Editorial: Top-down proteomics and proteoforms - special issue Andreas Tholey, Hartmut Schlüter Proteomics 24, 2200375 (2 pp) (2024) |
| 291 |
Application of sample displacement batch chromatography for fractionation of proteoforms Siti Nurul Hidayah , Ali Biabani, Manasi Gaikwad, Paula Nissen, Hannah Voß, Maria Riedner , Hartmut Schlüter , Bente Siebels Proteomics 24, 2200424 (11 pp) (2024) |
| 290 |
Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds Bruno Alves França, Sven Falke, Holger Rohde , Christian Betzel Scientific Reports 14, 2572 (13 pp) (2024) |
| 289 |
No Time to Die: How Cytomegaloviruses Suppress Apoptosis, Necroptosis, and Pyroptosis Yingqi Deng, Ana Agueda-Pinto, Wolfram Brune Viruses 16, 1272 (15 pp) (2024) |
| 288 |
Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules in cancer research Jan Hahn, Manuela Moritz, Anton Walter, Tamara Wieck, Ayham Moustafa, Wael Mansour, Charlotte Harms, Peter Stenzel, Jörg Heeren , Marie-Therese Haider, Tobias Lange, Hartmut Schlüter Proceedings of SPIE - The International Society for Optical Engineering 12846 (Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII) 128460C (2024) |
| 287 |
Preparation of Bunyavirus-Infected Cells for Electron Cryo-Tomography Fanny Ott, Märit-Runa Jönsson, Kay Grünewald , Jan Hellert -/- Editor: Pierre-Yves Lozach Methods in Molecular Biology Rift Valley Fever Virus. Methods and Protocols, 221-239 (2024), ISBN 978-1-0716-3925-2 |
| 286 |
Lecture: The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation Senders: Melad Henis (= Tabitha Rücker = Robin Scharrenberg = Melanie Richter = Lucas Baltussen = Shuai Hong = Durga Praveen Meka = Birgit Schwanke = Nagammal Neelagandan = Danie Daaboul = Nadeem Murtaza = Christoph Krisp = Sönke Harder = Hartmut Schlüter = Matthias Kneussel = Irm Hermans-Borgmeyer = Joris de Wit = Karun K. Singh = Kent E. Duncan = Froylan Calderón de Anda) Science Advances 10, eadf7001 (18 pp) (2024) Description: The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation |
| 285 |
present invention relates generally to vaccine for prophylaxis or treatment of infection by Lassa virus or of disorder relating to such infection Michael Jarvis, Thekla Mauch, Wolfram Brune , Eleonore Ostermann, Alec Redwood, Baca Chan, Andrew Davison, Jenna Nichols, Joseph Hughes, Matej Vucak, Heinrich Feldmann, Kyle Rosenke, Frederick Hansen, Nafomon Sogoba, Seydou Doumbia, Scott Nuismer, Peter Barry -/- Applicant: The Vaccine Group LTD Patent: WO 2024115785 (A1) 2024-06-06 |
| 284 |
Synthetic DNA construct encoding suppressor tRNA Zoya Ignatova , Suki Albers-Fomenko , Marcos Davyt, Nikhil Bharti -/- Applicants: Universität Hamburg Patent: WO 2024208970 (A2) 2024-10-10; EP 4442826 (A1) 2024-10-09 |
| 283 |
Pharmaceutical composition comprising multiple suppressor transfer RNAs Zoya Ignatova , Nikhil Bharti, Marcos Davyt -/- Applicants: Universität Hamburg Patent: WO 2024227728 (A1) 2024-11-07; EP 4458967 (A1) 2024-11-06 |
2023 | |
| 282 |
Tailored Synthetic sRNAs Dynamically Tune Multilayer Genetic Circuits Ana K. Velazquez Sanchez, Bjarne Klopprogge, Karl-Heinz Zimmermann, Zoya Ignatova ACS Synthetic Biology 12, 2524-2535 (2023) |
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Novel, Validated, 5-Point Photonumeric Scales for Assessment of the Perioral Region Windie Hayano, Martina Kerscher, Doris Day, Alexandra Ogilvie, Tatjana Pavicic, Ting Song Lim , Z. Paul Lorenc, Claudia A. Hernandez, Konstantin Frank, Nicholas Moellhoff, Valentina Prinz, Mia Cajkovsky, Rainer Pooth, Jeremy Green Aesthetic Surgery Journal 43, 1347-1356 (2023) |
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Novel, Validated 5-Point Photonumeric Scales for Assessment of the Neck and Décolleté Martina Kerscher, Jeremy Green, Doris Day, Alexandra Ogilvie, Tatjana Pavicic, Ting Song Lim , Windie Hayano, Z. Paul Lorenc, Claudia A. Hernandez, Konstantin Frank, Nicholas Moellhoff, Valentina Prinz, Mia Cajkovsky, Rainer Pooth Aesthetic Surgery Journal 43, NP560-NP572 (2023) |
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Direct 3D sampling of the embryonic mouse head: Layer-wise nanosecond infrared laser (NIRL) ablation from scalp to cortex for spatially resolved proteomics Jelena Navolic, Manuela Moritz, Hannah Voß, Simon Schlumbohm, Yannis Schumann, Hartmut Schlüter , Julia E. Neumann, Jan Hahn Analytical Chemistry 95, 17220-17227 (2023) |
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Thioxothiazolo[3,4-a]quinazoline derivatives inhibit the human cytomegalovirus alkaline nuclease Tianyu Zhang, Theodore I. Potgieter, Erik Kosche, Jessica Rückert, Eleonore Ostermann, Thomas Schulz, Martin Empting, Wolfram Brune Antiviral Research 217, 105696 (2023) |
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CogiTx1: A novel subtilisin A inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family Laritza Rojas, Aymara Cabrera-Muñoz, Luis A. Espinosa, Sergi Montané, Luis Alvarez-Lajonchere, Jesús D. Mojarena, Galina Moya, Julia Lorenzo, Luis J. González, Christian Betzel , Maday Alonso-del-Rivero Antigua Biochimie 213, 41-53 (2023) |
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Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors Stefan Wimmer, Katharina Hoff, Benedikt Martin, Martin Grewer, Laura Denni, Raquel Lascorz Massanet, Maria Valeria Raimondi, Emre F. Bülbül, Jelena Melesina, Sven-Kevin Hotop, Jörg Haupenthal, Holger Rohde , Peter Heisig, Anna K. H. Hirsch, Mark Brönstrup, Wolfgang Sippl, Ralph Holl Bioorganic Chemistry 131, 106331 (2023) |
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Reducing microtubule detyrosination improves heart function in HCM mice and human iPSC-engineered heart tissues Niels Pietsch, Christina Y. Chen, Svenja Kupsch, Lucas Bacmeister, Birgit Geertz, Marisol Herrera-Rivero, Hannah Voß, Elisabeth Krämer, Ingke Braren, Dirk Westermann, Hartmut Schlüter , Giulia Mearini, Saskia Schlossarek, Jolanda van der Velden, Matthew Caporizzo, Diana Lindner, Benjamin L. Prosser, Lucie Carrier bioRxiv 542365 (2023) |
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Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage Tatyana Danyukova, Assil-Ramin Alimy, Renata Voltolini Velho, Timur Alexander Yorgan, Giorgia Di Lorenzo, Simon von Kroge, Henning Tidow , J. Simon Wiegert, Irm Hermans-Borgmeyer, Thorsten Schinke , Tim Rolvien, Sandra Pohl Bone 177, 116927 (12 pp) (2023) |
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Oral Microbiota as Novel Biomarkers for Colorectal Cancer Screening Sama Rezasoltani, Hamid Asadzadeh Aghdaei, Seyedesomaye Jasemi, Maria Gazouli, Nikolas Dovrolis, Amir Sadeghi, Hartmut Schlüter , Mohammad Reza Zali, Leonardo Antonio Sechi, Mohammad Mehdi Feizabadi Cancers 15, 192 (14 pp) (2023) |
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Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function Devon Siemes, Pieter Vancamp, Boyka Markova, Philippa Spangenberg, Olga Shevchuk, Bente Siebels, Hartmut Schlüter , Steffen Mayerl, Heike Heuer, Daniel Robert Engel Cells 12, 2487 (14 pp) (2023) |
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Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections Patrick Y. A. Reinke, Edmarcia Elisa de Souza, Sebastian Günther, Sven Falke, Julia Lieske, Wiebke Ewert, Jure Loboda, Alexander Herrmann, Aida Rahmani Mashhour, Katarina Karnicar, Aleksandra Usenik, Nataša Lindic, Andreja Sekirnik, Viviane Fongaro Botosso, Gláucia Maria Machado Santelli, Josana Kapronezai, Marcelo Valdemir de Araújo, Taiana Tainá Silva-Pereira, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Lizdany Flórez-Álvarez, Danielle Bruna Leal de Oliveira, Edison Luiz Durigon, Paula Roberta Giaretta, Marcos Bryan Heinemann, Maurice Hauser, Brandon Seychell, Hendrik Böhler, Wioletta Rut, Marcin Drag, Tobias Beck , Russell Cox, Henry N. Chapman , Christian Betzel , Wolfgang Brehm, Winfried Hinrichs, Gregor Ebert, Sharissa L. Latham, Ana Marcia de Sá Guimarães, Dusan Turk, Carsten Wrenger, Alke Meents Communications Biology 6, 1058 (2023) |
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The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3 Dorothea Höpfner, Adam Cichy, Vivian Pogenberg, Christoph Krisp, Soraya Mezouar, Nina C. Bach, Jan Grotheer, Sandra Madariaga Zarza, Eric Martinez, Matteo Bonazzi, Matthias J. Feige, Stephan A. Sieber, Hartmut Schlüter , Aymelt Itzen Communications Biology 6, 1124 (25 pp) (2023) |
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Unsupervised meta-clustering identifies risk clusters in acute myeloid leukemia based on clinical and genetic profiles Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Peter Heisig, Sebastian Stasik, Julia-Annabell Georgi, Frank Kroschinsky, Friedrich Stölzel, Uwe Platzbecker, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang Hiddemann, Carsten Müller-Tidow, Hubert Serve, Claudia D. Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan W. Krause, Mathias Hänel, Wolfgang E. Berdel, Christoph Schliemann, Jiri Mayer, Maher Hanoun, Johannes Schetelig, Karsten Wendt, Martin Bornhäuser, Christian Thiede, Jan Moritz Middeke Communications Medicine 3, 68 (2023) |
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Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events George Allen, Benjamin Weiss, Olesya O. Panasenko, Susanne Huch, Zoltan Villanyi, Benjamin Albert, Daniel Dilg, Marina Zagatti, Paul Schaughency, Susan E. Liao, Jeff Corden, Christine Polte, David Shore, Zoya Ignatova , Vicent Pelechano, Martine A. Collart Genome Biology 24, 30 (27 pp) (2023) |
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Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning. Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke Haematologica 108, 690-704 (2023) |
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Cutaneous manifestations in Costello syndrome: HRAS p.Gly12Ser affects RIN1-mediated integrin trafficking in immortalized epidermal keratinocytes Theresa Nauth, Farhad Bazgir, Hannah Voß, Laura I Brandenstein, Niloufar Mosaddeghzadeh, Verena Rickassel, Sophia Deden, Christian Gorzelanny, Hartmut Schlüter , Mohammad R Ahmadian, Georg Rosenberger Human Molecular Genetics 32, 304-318 (2023) |
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Structure and dynamics of the penicillin-binding protein 3 from Staphylococcus epidermidis native and in complex with cefotaxime and vaborbactam Martin Schwinzer, Hévila Brognaro, Holger Rohde , Christian Betzel International Journal of Applied Biology and Pharmaceutical Technology 14, 60-75 (2023) |
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The Forms of the Lectin Tff2 Differ in the Murine Stomach and Pancreas: Indications for Different Molecular Functions Eva B. Znalesniak, Aikaterini Laskou, Franz Salm, Katharina Haupenthal, Sönke Harder, Hartmut Schlüter , Werner Hoffmann International Journal of Molecular Sciences 24, 7059 (18 pp) (2023) |
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Lipidome Analysis of Oropharyngeal Tumor Tissues Using Nanosecond Infrared Laser (NIRL) Tissue Sampling and Subsequent Mass Spectrometry Rupert Stadlhofer, Manuela Moritz, Marceline Manka Fuh, Jörg Heeren , Henrike Zech, Till S. Clauditz, Hartmut Schlüter , Christian S. Betz, Dennis Eggert, Arne Böttcher, Jan Hahn International Journal of Molecular Sciences 24, 7820 (16 pp) (2023) |
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Expression Profiling along the Murine Intestine: Different Mucosal Protection Systems and Alterations in Tff1-Deficient Animals Franz Salm, Eva B. Znalesniak, Aikaterini Laskou, Sönke Harder, Hartmut Schlüter , Werner Hoffmann International Journal of Molecular Sciences 24, 12684 (19 pp) (2023) |
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Effect of mRNA/tRNA mutations on translation speed: Implications for human diseases Marcos Davyt, Nikhil Bharti, Zoya Ignatova Journal of Biological Chemistry 299, 105089 (16 pp) (2023) |
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Isolation and genome sequencing of cytomegaloviruses from Natal multimammate mice (Mastomys natalensis) Frederick Hansen, Matej Vucak, Jenna Nichols, Joseph Hughes, Sidy Bane, Salvatore Camiolo, Ana da Silva Filipe, Eleonore Ostermann, Laura Staliunaite, Baca Chan, Thekla Mauch, Nafomon Sogoba, Daniel N. Streblow, Sebastian Voigt, Lisa Oestereich, Bernhard Ehlers, Alec J. Redwood, Heinz Feldmann, Wolfram Brune , Kyle Rosenke, Michael A. Jarvis, Andrew J. Davison Journal of General Virology 104, 001873 (20 pp) (2023) |
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Detection and Isolation of Circulating Tumor Cells from Breast Cancer Patients Using CUB Domain-Containing Protein 1 Kai Bartkowiak, Parinaz Mossahebi Mohammadi, Sebastian Gärtner, Marcel Kwiatkowski, Antje Andreas, Maria Geffken, Sven Peine, Karl Verpoort, Ursula Scholz, Thomas M. Deutsch, Laura L. Michel, Andreas Schneeweiss, Verena Thewes, Andreas Trumpp, Volkmar Müller, Sabine Riethdorf, Hartmut Schlüter , Klaus Pantel Journal of Proteome Research 22, 1213-1230 (2023) |
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The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition Timm O. Koller , Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I. M. Boshoff, Bertrand Beckert, Joanna C. Evans, Jan Schlemmer, Becky Sloan, Danielle M. Weiner, Laura E. Via, Atica Moosa, Thomas R. Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E. Barry, Digby F. Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N. Wilson , Rolf Müller Journal of the American Chemical Society 145, 851-863 (2023) Reprint: ChemRix 2022-vr3hn (2022) |
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Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens Sören M. M. Schuler, Gerrit Jürjens, Alexander Marker, Ulrike Hemmann, Astrid Rey, Stéphane Yvon, Marjorie Lagrevol, Mohamed Hamiti, Fabian Nguyen, Rolf Hirsch, Christoph Pöverlein, Andreas Vilcinskas, Peter Hammann, Daniel N. Wilson , Michael Mourez, Sebastien Coyne, Armin Bauer Microbiology Spectrum 11, 1-12 (2023) |
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Ready, steady, go: Rapid ribosomal scanning to reach start codons Helge Paternoga , Daniel N. Wilson Molecular Cell 83, 9-11 (2023) |
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Rhizochalinin exhibits anticancer activity and synergizes with EGFR inhibitors in glioblastoma in vitro models Sergey A. Dyshlovoy, Jessica Hauschild, Simone Venz, Christoph Krisp, Katharina Kolbe, Svenja Zapf, Sarina Heinemann, Krystian D. Fita, Larisa K. Shubina, Tatyana N. Makarieva, Alla G. Guzii, Tina Rohlfing, Moritz Kaune, Tobias Busenbender, Thomas Mair, Manuela Moritz, Ekaterina V. Poverennaya, Hartmut Schlüter , Volodymyr Serdyuk, Valentin A. Stonik, Judith Dierlamm, Carsten Bokemeyer, Malte Mohme, Manfred Westphal, Katrin Lamszus, Gunhild von Amsberg, Cecile L. Maire Molecular Pharmaceutics 20, 4994-5005 (2023) |
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Engineered tRNAs suppress nonsense mutations in cells and in vivo Suki Albers , Elizabeth C. Allen, Nikhil Bharti, Marcos Davyt, Disha Joshi, Carlos G. Perez-Garcia, Leonardo Santos, Rajesh Mukthavaram, Miguel Angel Delgado-Toscano, Brandon Molina, Kristen Kuakini, Maher Alayyoubi, Kyoung-Joo Jenny Park, Grishma Acharya, Jose A. Gonzalez, Amit Sagi, Susan E. Birket, Guillermo J. Tearney, Steven M. Rowe, Candela Manfredi, Jeong S. Hong, Kiyoshi Tachikawa, Priya Karmali, Daiki Matsuda, Eric J. Sorscher, Pad Chivukula, Zoya Ignatova Nature 618, 842-848 (2023) |
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Structural basis for translation inhibition by the glycosylated drosocin peptide Timm O. Koller , Martino Morici, Max Berger, Haaris A. Safdari, Deepti S. Lele, Bertrand Beckert, Kanwal J. Kaur, Daniel N. Wilson Nature Chemical Biology 19, 1072-1081 (2023) |
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Variable microtubule architecture in the malaria parasite Josie L. Ferreira, Vojtech Pražák, Daven Vasishtan, Marc Siggel, Franziska Hentzschel, Annika M. Binder, Emma Pietsch, Jan Kosinski , Friedrich Frischknecht, Tim W. Gilberger, Kay Grünewald Nature Communications 14, 1216 (2023) Reprint: bioRxiv 488170 (2022) |
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An integrated organoid omics map extends modeling potential of kidney disease Moritz Lassé, Jamal El Saghir, Celine C. Berthier, Sean Eddy, Matthew Fischer, Sandra D. Laufer, Dominik Kylies, Arvid Hutzfeldt, Léna Lydie Bonin, Bernhard Dumoulin, Rajasree Menon, Virginia Vega-Warner, Felix Eichinger, Fadhl Alakwaa, Damian Fermin, Anja M. Billing, Akihiro Minakawa, Phillip J. McCown, Michael P. Rose, Bradley Godfrey, Elisabeth Meister, Thorsten Wiech, Mercedes Noriega, Maria Chrysopoulou, Paul Brandts, Wenjun Ju, Linda Reinhard, Elion Hoxha, Florian Grahammer, Maja T. Lindenmeyer, Tobias B. Huber, Hartmut Schlüter , Steffen Thiel, Laura H. Mariani, Victor G. Puelles, Fabian Braun, Matthias Kretzler, Fatih Demir, Jennifer L. Harder, Markus M. Rinschen Nature Communications 14, 4903 (21 pp) (2023) |
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Structural conservation of antibiotic interaction with ribosomes Helge Paternoga , Caillan Crowe-McAuliffe, Lars V. Bock, Timm O. Koller , Martino Morici, Bertrand Beckert, Alexander G. Myasnikov, Helmut Grubmüller, Jirí Novácek, Daniel N. Wilson Nature Structural & Molecular Biology 30, 1380-1392 (2023) |
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Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein Harry M. Williams, Sigurdur R. Thorkelsson, Dominik Vogel, Morlin Milewski, Carola Busch, Stephen Cusack, Kay Grünewald , Emmanuelle R. J. Quemin, Maria Rosenthal Nucleic Acids Research 51, 1424-1442 (2023) |
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Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR Nozomu Obana, Hiraku Takada, Caillan Crowe-McAuliffe, Mizuki Iwamoto, Artyom A. Egorov, Kelvin J. Y. Wu, Shinobu Chiba, Victoriia Murina, Helge Paternoga , Ben I. C. Tresco, Nobuhiko Nomura, Andrew G. Myers, Gemma C. Atkinson, Daniel N. Wilson , Vasili Hauryliuk Nucleic Acids Research 51, 4536-4554 (2023) |
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Novel Validated Five-point Photonumeric Scales for Assessment of Static and Dynamic Forehead Lines Ting Song Lim , Martina Kerscher, Alexandra Ogilvie, Tatjana Pavicic, Paul Z. Lorenc, Konstantin Frank, Valentina Prinz, Mia Cajkovsky, Rainer Pooth, Claudia A. Hernandez Plastic & Reconstructive Surgery-Global Open 11, e5287 (2023) |
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Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability Aleksi Sutinen, Dirk Paffenholz, Giang Thi Tuyet Nguyen, Salla Ruskamo, Andrew E. Torda , Petri Kursula PLoS One 18, e0284532 (29 pp) (2023) |
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Viral dew: Phase separation and the formation of viral replication compartments Jens B. Bosse, Wolfram Brune PLoS Pathogens 19, e1011145 (7 pp) (2023) |
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Structural and functional characterization of the Sin Nombre virus L protein Kristina Meier, Sigurdur R. Thorkelsson, Quentin Durieux Trouilleton, Dominik Vogel, Dingquan Yu, Jan Kosinski , Stephen Cusack, Hélène Malet, Kay Grünewald , Emmanuelle R. J. Quemin, Maria Rosenthal PLoS Pathogens 19, e1011533 (23 pp) (2023) |
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Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction Derek C. K. Chan, Inokentijs Josts, Kalinka Koteva, Gerard D. Wright, Henning Tidow , Lori L. Burrows Proceedings of the National Academy of Sciences of the United States of America 120, e222125312 (12 pp) (2023) |
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Initiation and modulation of Tau protein phase separation by the drug suramin Prabhu Rajaiah Prince, Janine Hochmair, Hévila Brognaro, Susanna Gevorgyan, Maximilian Franck, Robin Schubert, Kristina Lorenzen, Selin Yazici, Eckhard Mandelkow, Susanne Wegmann, Christian Betzel Scientific Reports 13, 3963 (13 pp) (2023) |
| 240 |
Formation kinetics and physicochemical properties of mesoscopic Alpha-Synuclein assemblies modulated by sodium chloride and a distinct pulsed electric field Mengying Wang, Roland Thuenauer, Robin Schubert, Susanna Gevorgyan, Kristina Lorenzen, Hévila Brognaro, Christian Betzel Soft Matter 19, 1363-1372 (2023) |
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A Virus Genetic System to Analyze the Fusogenicity of Human Cytomegalovirus Glycoprotein B Variants Xuan Zhou, Giorgia Cimato, Yihua Zhou, Giada Frascaroli, Wolfram Brune Viruses 15, 979 (17 pp) (2023) |
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MDB-19. Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level Shweta Godbole, Hannah Voß, Simon Schlumbohm, Yannis Schumann, Bojia Peng, Martin Mynarek, Stefan Rutkowski, Matthias Dottermusch, Mario M. Dorostkar, Andrey Koshunov, Thomas Mair, Stefan M. Pfister, Philipp Neumann, Christian Hartmann, Joachim Weis, Friederike Liesche-Starnecker, Yudong Guan, Hartmut Schlüter , Ulrich Schüller, Christoph Krisp, Julia E. Neumann Neuro-Oncology 25 (Suppl. 1) i66-i66 (2023) |
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A Jumbled Code: Unveiling the Enigmatic DNA Binding Patterns of the Marr Family Eduardo Horta Santos, Paulo Henrique Gomes dos Santos, Rafael Eduardo Oliveira Rocha, Lucas Bleicher Proceedings of the 47th Annual Meeting of the Brazilian Biophysical Society 1, 164279 (2023) |
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Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro Janine Hochmair, Christian Exner, Christian Betzel , Eckhard Mandelkow, Susanne Wegmann Methods in Molecular Biology 2551 (Protein Aggregation) 225-243 (2023) |
| 235 |
Prefusion-stabilized herpesvirus glycoprotein-B for production of antibodies or therapeutic agents such as vaccines Kay Grünewald , Benjamin Vollmer, Marija Backovic, Maya Topf, Anna Hernández Durán, Victor Jefferys, Daven Vasishtan -/- Applicants: Leibnitz Institut für Virologie, Institut Pasteur Patent: WO 2023046923 (A1) 2023-03-30; US 2023096087 (A1) 2023-03-30 |
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Synthetic Transfer RNA with Modified Nucleotides Zoya Ignatova , Suki Albers -/- Applicants: Universität Hamburg Patent: WO 2023118456 (A1) 2023-06-29; EP 4202045 (A1) 2023-06-28 |
2022 | |
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Improving the Robustness of Engineered Bacteria to Nutrient Stress Using Programmed Proteolysis Klara Szydlo, Zoya Ignatova , Thomas E. Gorochowski ACS Synthetic Biology 11, 1049-1059 (2022) |
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Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development Amr Moustafa, Markus Perbandt , Eva Liebau, Christian Betzel , Sven Falke Acta Crystallographica, Section F: Structural Biology Communications 78, 232-240 (2022) |
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Comparative
Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics Yang Zhang, Benjamin Dreyer, Natalia Govorukhina, Alexander M. Heberle, Saša Koncarevic, Christoph Krisp, Christiane A. Opitz, Pauline Pfänder, Rainer Bischoff, Hartmut Schlüter , Marcel Kwiatkowski, Kathrin Thedieck, Peter L. Horvatovich Analytical Chemistry 94, 10893-10906 (2022) |
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Immunoprecipation assay to quantify the amount of tRNAs associated with their interacting proteins in tissue and cell culture Sarada Das, Amila Zuko, Robin Thompson, Erik Storkebaum, Zoya Ignatova Bio-Protocol 12, e4335 (2022) |
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Observation of a single protein by ultrafast X-ray diffraction Tomas Ekeberg, Dameli Assalauova, Johan Bielecki, Rebecca Boll, Benedikt J. Daurer, Lutz A. Eichacker, Linda E. Franken, Davide E. Galli, Luca Gelisio, Lars Gumprecht, Laura H. Gunn, Janos Hajdu, Robert Hartmann, Dirk Hasse, Alexandr Ignatenko, Jayanath Koliyadu, Olena Kulyk, Ruslan Kurta, Markus Kuster, Wolfgang Lugmayr, Jannik Lübke, Adrian P. Mancuso, Tommaso Mazza, Carl Nettelblad, Yevheniy Ovcharenko, Daniel E. Rivas, Max Rose, Amit K. Samanta, Philipp Schmidt, Egor Sobolev, Nicusor Timneanu, Sergej Usenko, Daniel Westphal, Tamme Wollweber, Lena Worbs, P. Lourdu Xavier, Hazem Yousef, View ORCID ProfileKartik Ayyer, Henry N. Chapman , Jonas A. Sellberg, Carolin Seuring , Ivan Vartaniants , Jochen Küpper , Michael Meyer, Filipe R. N. C. Maia bioRxiv 483477 (19 pp) (2022) |
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Survival Advantage of Lymphadenectomy in Patients with Ovarian Cancer Atanas Ignatov, Sheref Salim Hassan, Stylianos Ivros, Thomas Papathemelis, Zoya Ignatova , Holm Eggemann Cancer Investigation 40, 621-628 (2022) |
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Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients Christine Nitschke, Benedikt Markmann, Marie Tölle, Jolanthe Kropidlowski, Yassine Belloum, Mara R. Goetz, Hartmut Schlüter , Marcel Kwiatkowski, Marianne Sinn, Jakob Izbicki, Klaus Pantel, Cenap Güngör, Faik G. Uzunoglu, Harriet Wikman Cancers 14, 4405 (12 pp) (2022) |
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Na,K-ATPase α1 and β-subunits show distinct localizations in the nervous tissue of the large milkweed bug Marlena Herbertz, Sönke Harder, Hartmut Schlüter , Christian Lohr, Susanne Dobler Cell & Tissue Research 388, 503-519 (2022) |
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Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans Martin Zickler, Stephanie Stanelle-Bertram, Sandra Ehret, Fabian Heinrich, Philine Lange, Berfin Schaumburg, Nancy Mounogou Kouassi, Sebastian Beck, Michelle Yvonne Jäckstein, Oliver Mann, Susanne Krasemann, Maria Schroeder, Dominik Jarczak, Axel Nierhaus, Stefan Kluge, Manuela Peschka, Hartmut Schlüter , Thomas Renné, Klaus Püschel, Andreas Kloetgen, Ludger Scheja, Benjamin Ondruschka, Jörg Heeren , Gülsah Gabriel Cell Metabolism 34, 1-2 (2022) |
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Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication Enrico Caragliano, Stefano Bonazza, Giada Frascaroli, Jiajia Tang, Timothy K. Soh, Kay Grünewald , Jens B. Bosse, Wolfram Brune Cell Reports 38, 110469 (21 pp) (2022) |
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Centrosome-dependent microtubule modifications set the conditions for axon formation Durga Praveen Meka, Oliver Kobler, Shuai Hong, Carina Meta Friedrich, Souhaila Wüsthoff, Melad Henis, Birgit Schwanke, Christoph Krisp, Nessa Schmuelling, René Rueter, Tabitha Rücker, Ewelina Betleja, Tao Cheng, Moe R. Mahjoub, Peter Soba, Hartmut Schlüter , Eugenio F. Fornasiero, Froylan Calderon de Anda Cell Reports 39, 110686 (28 pp) (2022) |
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Circulating Cellular Communication Network Factor 1 Protein as a Sensitive Liquid Biopsy Marker for Early Detection of Breast Cancer Kai Bartkowiak, Isabel Heidrich, Marcel Kwiatkowski, Maggie Banys-Paluchowski, Antje Andreas, Marcus Wurlitzer, Maria Geffken, Hannah Voß, Tanja Zeller, Stefan Blankenberg, Sven Peine, Simon A. Joosse, Volkmar Müller, Hartmut Schlüter , Leticia Oliveira-Ferrer, Klaus Pantel Clinical Chemistry 68, 344-353 (2022) |
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Cell-Free Blood Cell Secretome (BCS) Counteracts Skin Aging: Multi-Center Prospective Regenerative Aesthetic Medicine Study Using Exokine®. Martina Kerscher, Sylvia Wagner-Schiffler, Ernst Magnus Noah, Tanja Fischer, Daniela Greiner-Krüger, Sonja Sattler, Tanju Kaptan, Attyla Drabik, Glyn Hamed, Julio Reinecke, Jana Wehling Clinical, Cosmetic and Investigational Dermatology 15, 1157-1173 (2022) |
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Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease Vasundara Srinivasan, Hévila Brognaro, Prince R. Prabhu, Edmarcia Elisa de Souza, Sebastian Günther, Patrick Y. A. Reinke, Thomas J. Lane, Helen Ginn, Huijong Han, Wiebke Ewert, Janina Sprenger, Faisal H. M. Koua, Sven Falke, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Bruno Alves França, Mengying Wang, Angélica Luana C. Barra, Markus Perbandt , Martin Schwinzer, Christina Schmidt, Lea Brings, Kristina Lorenzen, Robin Schubert, Rafael Rahal Guaragna Machado, Erika Donizette Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Stephan Niebling, Angelica Struve Garcia, Oleksandr Yefanov, Julia Lieske, Luca Gelisio, Martin Domaracky, Philipp Middendorf, Michael Groessler, Fabian Trost, Marina Galchenkova, Aida Rahmani Mashhour, Sofiane Saouane, Johanna Hakanpää, Markus Wolf, Maria M. Garcia-Alai , Dusan Turk, Arwen R. Pearson , Henry N. Chapman , Winfried Hinrichs, Carsten Wrenger, Alke Meents , Christian Betzel Communications Biology 5, 805 (12 pp) (2022) |
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Exploring Nucleation Pathways in Distinct Physicochemical Environments Unveiling Novel Options to Modulate and Optimize Protein Crystallization Mengying Wang, Angélica Luana C. Barra, Hévila Brognaro, Christian Betzel Crystals 12, 437 (22 pp) (2022) |
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Comparative Study to Characterise the Pharmaceutical Potential of Synthesised Snake Venom Bradykinin-Potentiating Peptides In Vivo Aisha Munawar, Fakhar Zaman, Muhammad Waqas Ishaq, Khwaja Ali Hassan, Saima Masood, Zahid Ali, Khalid Abdul Majeed, Ahmed Akrem, Syed Abid Ali, Christian Betzel Current Medicinal Chemistry 29, 6422-6432 (2022) |
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Comprehensive Structural and Functional Characterization of a Seed γ-thionin as a Potent Bioactive Molecule Against Fungal Pathogens and Insect Pests Binish Khaliq, Mohnad Abdalla, Sohaib Mehmood, Ahsan Saeed, Aisha Munawar, Muhammad Qamar Saeed, Qamar Saeed, Muhammad Ibrahim, Zahid Ali, Saber Hussain, Wafa Ali Eltayb, Christian Betzel , Ahmed Akrem Current Medicinal Chemistry 29, 6446-6462 (2022) |
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Mouse Models for Cytomegalovirus Infections in Newborns and Adults Ilija Brizic, Berislav Lisnic, Fran Krstanovic, Wolfram Brune , Hartmut Hengel, Stipan Jonjic Current Protocols 2, e537 (22 pp) (2022) |
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The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield Alejandro Villalta, Alain Schmitt, Leandro F. Estrozi, Emmanuelle R. J. Quemin, Jean-Marie Alempic, Audrey Lartigue, Vojtech Pražák, Lucid Belmudes, Daven Vasishtan, Agathe M. G. Colmant, Flora A. Honoré, Yohann Couté, Kay Grünewald , Chantal Abergel eLife 11, e77607 (22 pp) (2022) |
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Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines Anja Konietzny, Jasper Grendel, Alan Kadek, Michael Bucher, Yuhao Han, Nathalie Hertrich, Dick H. W. Dekkers, Jeroen A. A. Demmers, Kay Grünewald , Charlotte Uetrecht, Marina Mikhaylova EMBO Journal 41, e106523 (24 pp) (2022) |
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Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates Janine Hochmair, Christian Exner, Maximilian Franck, Alvaro Dominguez-Baquero, Lisa Diez, Hévila Brognaro, Matthew L. Kraushar, Thorsten Mielke, Helena Radbruch, Senthilvelrajan Kaniyappan, Sven Falke, Eckhard Mandelkow, Christian Betzel , Susanne Wegmann EMBO Journal 41, e108882 (28 pp) (2022) |
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Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination Dominique-Maurice Kehlenbeck, Daouda A. K. Traore, Inokentijs Josts, Simon Sander, Martine Moulin, Michael Härtlein, Sylvain Prevost, V. Trevor Forsyth , Henning Tidow FEBS Journal 289, 2959-2970 (2022) Erratum: FEBS Journal 290, 3290-3290 (2023) |
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Hydrazones and thiosemicarbazones targeting protein-protein-interactions of SARS-CoV-2 papain-like protease Wiebke Ewert, Sebastian Günther, Francesca Miglioli, Sven Falke, Patrick Y. A. Reinke, Stephan Niebling, Christian Günther, Huijong Han, Vasundara Srinivasan, Hévila Brognaro, Julia Lieske, Kristina Lorenzen, Maria M. Garcia-Alai , Christian Betzel , Mauro Carcelli, Winfried Hinrichs, Dominga Rogolino, Alke Meents Frontiers in Chemistry 10, 832431 (2022) |
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Biophysical screening pipeline for Cryo-EM grid preparation of membrane proteins Stephan Niebling, Katharina Veith, Benjamin Vollmer, Javier Lizarrondo, Osvaldo Burastero, Janina Schiller, Angelica Struve Garcia, Philipp Lewe, Carolin Seuring , Susanne Witt, Maria M. Garcia-Alai Frontiers in Molecular Biosciences 9, 882288 (19 pp) (2022) |
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cADPR Does Not Activate TRPM2 Winnie Maria Riekehr, Simon Sander, Jelena Pick, Henning Tidow , Andreas Bauche, Andreas H. Guse , Ralf Fliegert International Journal of Molecular Sciences 23, 3163 (14 pp) (2022) |
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Tissue Sampling and Homogenization with NIRL Enables Spatially Resolved Cell Layer Specific Proteomic Analysis of the Murine Intestine Hannah Voß, Manuela Moritz, Penelope Pelczar, Nicola Gagliani, Samuel Huber , Vivien Nippert, Hartmut Schlüter , Jan Hahn International Journal of Molecular Sciences 23, 6132 (15 pp) (2022) |
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Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer Gunhild von Amsberg, Mirjam Zilles, Wael Y. Mansour , Philipp Gild, Winfried Alsdorf, Moritz Kaune, Lukas Böckelmann, Jessica Hauschild, Christoph Krisp, Tina Rohlfing, Ceren Saygi, Malik Alawi, Alexandra Zielinski, Claudia Langebrake, Su Jung Oh-Hohenhorst, Sven Perner, Derya Tilki, Hartmut Schlüter , Markus Graefen, Sergey A. Dyshlovoy, Carsten Bokemeyer International Journal of Molecular Sciences 23, 14948 (2022) |
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Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions Jens Weste, Till Houben, Sönke Harder, Hartmut Schlüter , Eva Lücke, Jens Schreiber, Werner Hoffmann International Journal of Molecular Sciences 23, 15359 (18 pp) (2022) |
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Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive Kara A. Zielinski, Andreas Prester, Hina Andaleeb, Soi Bui, Oleksandr Yefanov, Lucrezia Catapano, Alessandra Henkel, Max O. Wiedorn, Olga Lorbeer, Eva Crosas, Jan Meyer, Valerio Mariani, Martin Domaracky, Thomas A. White , Holger Fleckenstein, Iosifina Sarrou, Nadine Werner, Christian Betzel , Holger Rohde , Martin Aepfelbacher , Henry N. Chapman , Markus Perbandt , Roberto A. Steiner, Dominik Oberthür IUCrJ 9, 778-791 (2022) |
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Solution Structure and Conformational Flexibility of a Polyketide Synthase Module Maja Klaus, Emanuele Rossini, Andreas Linden, Karthik S. Paithankar, Matthias Zeug, Zoya Ignatova , Henning Urlaub, Chaitan Khosla, Jürgen Köfinger, Gerhard Hummer, Martin Grininger JACS Au 1, 2162-2171 (2022) |
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Intrinsically disordered plant protein PARCL colocalizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD Anna Ostendorp, Steffen Ostendorp, Yuan Zhou, Zoé Chaudron, Lukas Wolffram, Khadija Rombi, Linn von Pein, Sven Falke, Cy M. Jeffries, Dmitri I. Svergun, Christian Betzel , Richard J. Morris, Friedrich Kragler, Julia Kehr Journal of Biological Chemistry 198, 102631 (14 pp) (2022) |
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New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain Simon Sander, Isabel Mueller, Maria M. Garcia-Alai , Annette Nicke, Henning Tidow Journal of Biological Chemistry 298, 102495 (9 pp) (2022) |
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Insights on Skin Quality and Clinical Practice Trends in Asia Pacific and a Practical Guide to Good Skin Quality from the Inside Out Je-Young Park, Jeng-Feng Chen, Hosung Choi, Wilson W. S. Ho, Ni Nyoman Indra Lesthari, Joyce Teng Ee Lim, Ting Song Lim , Stephen Lowe, Beverly Ong-Amoranto, Vasanop Vachiramon, Rungsima Wanitphakdeedecha, Martina Kerscher Journal of Clinical and Aesthetic Dermatology 15, 10-21 (2022) |
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Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy Hande Aypek, Christoph Krisp, Shun Lu, Shuya Liu, Dominik Kylies, Oliver Kretz, Guochao Wu, Manuela Moritz, Kerstin Amann, Kerstin Benz, Ping Tong, Zheng-mao Hu, Sulaiman M. Alsulaiman, Arif O. Khan, Maik Grohmann, Timo Wagner, Janina Müller-Deile, Hartmut Schlüter , Victor G. Puelles, Carsten Bergmann, Tobias B. Huber, Florian Grahammer Journal of Clinical Investigation 132, e147253 (14 pp) (2022) |
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Approach to differentiate between hyaluronic acid skin quality boosters and fillers based on their physicochemical properties Linda Kleine-Börger , Robert S. A. Meyer, Alexander Kalies, Martina Kerscher Journal of Cosmetic Dermatology 21, 149-157 (2022) |
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Validated 5-Point photonumeric scales for the assessment of the periorbital region Tatjana Pavicic, Rainer Pooth, Valentina Prinz, Mia Cajkovsky, Jeremy B. Green, Claudia A. Hernandez, Daniel S. Mueller, Sonja Sattler, Heike Klepetko, Doris Day, Martina Kerscher, Atchima Suwanchinda, Sebastian Cotofana, Konstantin Frank, Sabrina G. Fabi Journal of Cosmetic Dermatology 21, 158-166 (2022) |
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Validated 5-Point photonumeric scales for the assessment of hand atrophy Jeremy B. Green, Tatjana Pavicic, Rainer Pooth, Valentina Prinz, Mia Cajkovsky, Claudia A. Hernandez, Daniel S. Mueller, Sonja Sattler, Heike Klepetko, Martina Kerscher, Atchima Suwanchinda, Sabrina G. Fabi, Sebastian Cotofana, Konstantin Frank, Doris Day Journal of Cosmetic Dermatology 21, 933-939 (2022) |
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Aesthetic medicine - Quo Vadis? Sebastian Cotofana, Sonja Sattler, Konstantin Frank, Claudia A. Hernandez, Tatjana Pavicic, Jeremy B. Green, Martina Kerscher, Peter Peng, Michael Gold, Rainer Pooth Journal of Cosmetic Dermatology 21, 6526-6527 (2022) |
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Calcium Hydroxyapatite Filler With Integral Lidocaine CaHA (+) for Soft Tissue Augmentation: Results from an Open-Label Multicenter Clinical Study. Tatjana Pavicic, Gerhard Sattler, Tanja Fischer, Thomas Dirschka, Martina Kerscher, Gerd Gauglitz, Hanna Dersch, Maria Kravtsov, Iryna Heide, Welf Prager Journal of Drugs in Dermatology 21, 481-487 (2022) |
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Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E Christian Sinzger, Gabriele Hahn, Margarete Digel, Ruth Katona, Kerstin Laib Sampaio, Martin Messerle, Hartmut Hengel, Ulrich Koszinowski, Wolfram Brune , Barbara Adler Journal of General Virology 103, 359-368 (2022) |
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Population Dynamics of Stretching Excitations of p-Azido-phenylalanine Incorporated in Calmodulin-Peptide Complexes Matthias Ruppert, Anne Creon, Henning Tidow , Nils Huse Journal of Physical Chemistry B 126, 368-375 (2022) |
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Total synthesis and biological evaluation of paenilamicins from the honey bee pathogen Paenibacillus larvae Timur Bulatov, Sebastian Gensel, Andi Mainz, Tam Dang, Timm O. Koller , Kerstin Voigt, Julia Ebeling, Daniel N. Wilson , Elke Genersch, Roderich D. Süssmuth Journal of the American Chemical Society 144, 288-296 (2022) |
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Stopped-flow-time-resolved SAXS for studies of ligand-driven protein dimerization Henning Tidow , Inokentijs Josts Methods in Enzymology 677, 251-262 (2022) |
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Studying integral membrane protein by SANS using stealth reconstitution systems Inokentijs Josts, Dominique-Maurice Kehlenbeck, Julius Nitsche, Henning Tidow Methods in Enzymology 677, 417-432 (2022) |
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The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils Robert Bücker, Carolin Seuring , Cornelia Cazey, Katharina Veith, Maria M. Garcia-Alai , Kay Grünewald , Meytal Landau Nature Communications 13, 4356 (11 pp) (2022) |
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers Susannah Holmes, Henry J. Kirkwood, Richard Bean, Klaus Giewekemeyer, Andrew V. Martin, Marjan Hadian-Jazi, Max O. Wiedorn, Dominik Oberthür , Hugh Marman, Luigi Adriano, Nasser Al-Qudami, Saša Bajt, Imrich Barák, Sadia Bari, Johan Bielecki, Sandor Brockhauser, Mathew A. Coleman, Francisco Cruz-Mazo, Cyril Danilevski, Katerina Dörner, Alfonso M. Gañán-Calvo, Rita Graceffa, Hans Fanghor, Michael Heymann, Matthias Frank, Alexander Kaukher, Yoonhee Kim, Bostjan Kobe, Juraj Knoška, Torsten Laurus, Romain Letrun, Luis Maia, Marc Messerschmidt, Markus Metz, Thomas Michelat, Grant Mills, Serguei Molodtsov, Diana C. F. Monteiro, Andrew J. Morgan, Astrid Münnich, Gisel E. Peña Murillo, Gianpietro Previtali, Adam Round, Tokushi Sato, Robin Schubert, Joachim Schulz, Megan Shelby, Carolin Seuring , Jonas A. Sellberg, Marcin Sikorski, Alessandro Silenzi, Stephan Stern, Jolanta Sztuk-Dambietz, Janusz Szuba, Martin Trebbin , Patrik Vagovic, Thomas Ve, Britta Weinhausen, Krzysztof Wrona, Paul Lourdu Xavier, Chen Xu, Oleksandr Yefanov, Keith A. Nugent, Henry N. Chapman , Adrian P. Mancuso, Anton Barty, Brian Abbey, Connie Darmanin Nature Communications 13, 4708 (13 pp) (2022) |
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Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics Caillan Crowe-McAuliffe, Victoriia Murina, Kathryn J. Turnbull , Susanne Huch, Marje Kasari, Hiraku Takada, Lilit Nersisyan, Arnfinn Sundsfjord, Kristin Hegstad, Gemma C. Atkinson, Vicent Pelechano, Daniel N. Wilson , Vasili Hauryliuk Nature Communications 13 (13 pp) 1860 (2022) |
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PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling Maria Thürmer, André Gollowitzer, Helmut Pein, Konstantin Neukirch, Elif Gelmez, Lorenz Waltl, Natalie Wielsch, René Winkler, Konstantin Löser, Julia Grander, Madlen Hotze, Sönke Harder, Annika Döding, Martina Meßner, Fabiana Troisi, Maximilian Ardelt, Hartmut Schlüter , Johanna Pachmayr, Óscar Gutiérrez-Gutiérrez, Karl Lenhard Rudolph, Kathrin Thedieck, Ulrike Schulze-Späte, Cristina González-Estévez, Christian Kosan, Ales Svatos, Marcel Kwiatkowski, Andreas Koeberle Nature Communications 2982 (21 pp) (2022) |
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Putting the antibiotics chloramphenicol and linezolid into context Caillan Crowe-McAuliffe, Daniel N. Wilson Nature Structural & Molecular Biology 29, 79-81 (2022) |
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Diagnostic potential of extracellular vesicles in meningioma patients Franz L. Ricklefs, Cecile L. Maire, Kathrin Wollmann, Lasse Dührsen, Krystian D. Fita, Felix Sahm, Christel Herold-Mende, Andreas von Deimling, Katharina Kolbe, Mareike Holz, Leonie Bergmann, Marceline Manka Fuh, Hartmut Schlüter , Malik Alawi, Rudolph Reimer, Sven Peine, Markus Glatzel, Manfred Westphal, Katrin Lamszus Neuro-Oncology 24, 2078-2090 (2022) |
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Tracing transport of protein aggregates in microgravity versus unit gravity crystallization Arayik Martirosyan, Sven Falke, Deborah McCombs, Martin Cox, Christopher D. Radka, Jan Knop, Christian Betzel , Lawrence J. DeLucas npj Microgravity 8, 4 (12 pp) (2022) |
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Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes Timm O. Koller , Kathryn J. Turnbull , Karolis Vaitkevicius, Caillan Crowe-McAuliffe, Mohammad Roghanian, Ondrej Bulvas, Jose A. Nakamoto, Tatsuaki Kurata, Christina Julius, Gemma C. Atkinson, Jörgen Johansson, Vasili Hauryliuk, Daniel N. Wilson Nucleic Acids Research 50, 11285-11300 (2022) |
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Structure of Escherichia coli heat shock protein Hsp15 in complex with the ribosomal 50S subunit bearing peptidyl-tRNA Haaris A. Safdari, Sergo Kasvandik, Christine Polte, Zoya Ignatova , Tanel Tenson, Daniel N. Wilson Nucleic Acids Research 50, 12515-12526 (2022) |
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Thermosensitive PLGA-PEG-PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy Sonja Heine, Antonio Aguilar-Pimentel, Dennis Russkamp, Francesca Alessandrini, Valérie Gailus-Durner, Helmut Fuchs, Markus Ollert, Reinhard Bredehorst, Caspar Ohnmacht, Ulrich M. Zissler, Martin Hrabe de Angelis, Carsten B. Schmidt-Weber, Simon Blank Pharmaceutics 14, 1527 (16 pp) (2022) |
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Intermittent bulk release of human cytomegalovirus Felix J. Flomm, Timothy K. Soh, Carola Schneider, Linda Wedemann, Hannah M. Britt, Konstantinos Thalassinos, Søren Pfitzner, Rudolph Reimer, Kay Grünewald , Jens B. Bosse PLoS Pathogens 18, e1010575 (32 pp) (2022) |
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The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation Maximiliane Wieland, Mikael Holm, Emily J. Rundlet, Martino Morici, Timm O. Koller , Tinashe P. Maviza, Domen Pogorevc, Ilya A. Osterman, Rolf Müller, Scott C. Blanchard, Daniel N. Wilson Proceedings of the National Academy of Sciences of the United States of America 119, e211421411 (9 pp) (2022) |
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The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+-binding domain essential for structural integrity and channel activity Simon Sander, Jelena Pick, Ellen Gattkowski, Ralf Fliegert, Henning Tidow Protein Science 31, e4320 (12 pp) (2022) |
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The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner Anuradha Tarafdar, Nina Wolska, Christoph Krisp, Hartmut Schlüter , Giordano Pula Redox Biology 52, 102287 (17 pp) (2022) |
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mRNAs sequestered in stress granules recover nearly completely for translation Sarada Das, Leonardo Santos, Antonio Virgilio Failla, Zoya Ignatova RNA Biology 19, 877-884 (2022) |
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Structure and activity of the DHNA Coenzyme-A Thioesterase from Staphylococcus aureus providing insights for innovative drug development Aline Melro Murad, Hévila Brognaro, Sven Falke, Jasmin Lindner, Markus Perbandt , Celestin Mudogo, Robin Schubert, Carsten Wrenger, Christian Betzel Scientific Reports 12, 4313 (14 pp) (2022) |
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Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors Markus Perbandt , Nadine Werner, Andreas Prester, Holger Rohde , Martin Aepfelbacher , Winfried Hinrichs, Christian Betzel Scientific Reports 12, 5510 (12 pp) (2022) |
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Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract Susanna Gevorgyan, Robin Schubert, Sven Falke, Kristina Lorenzen, Karen Trchounian, Christian Betzel Scientific Reports 12, 14077 (12 pp) (2022) |
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Microinjections with hyaluronic acid in combination with glycerol: How do they influence biophysical viscoelastic skin properties? Linda Kleine-Börger , Matthias Hofmann , Martina Kerscher Skin Research and Technology 28, 633-642 (2022) |
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Protocol for live-cell fluorescence-guided cryoFIB-milling and electron cryo-tomography of virus-infected cells Linda E. Franken, Rene Rosch, Ulrike Laugks, Kay Grünewald STAR Protocols 3, 101696 (43 pp) (2022) |
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Herpesvirus Replication Compartments: Dynamic Biomolecular Condensates Enrico Caragliano, Wolfram Brune , Jens B. Bosse Viruses 14, 960 (10 pp) (2022) |
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Understanding Host-Virus Interactions: Assessment of Innate Immune Responses in Mastomys natalensis Cells after Arenavirus Infection Nele Marie Brinkmann, Chris Hoffmann, Stephanie Wurr, Elisa Pallasch, Julia Hinzmann, Eleonore Ostermann, Wolfram Brune , Maria Elisabeth Eskes, Lukas Jungblut, Stephan Günther , Ludmilla Unrau, Lisa Oestereich Viruses 14, 1986 (22 pp) (2022) |
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Formation of β-Lactoglobulin Self-Assemblies via Liquid-Liquid Phase Separation for Applications beyond the Biological Functions Tuo-Di Zhang, Xudong Deng, Mengying Wang, Liang-Liang Chen, Xue-Ting Wang, Chen-Yuan Li, Wen-Pu Shi, Wen-Juan Lin, Qiang Li, Weichun Pan, Xiaodan Ni, Tiezheng Pan, Da-Chuan Yin ACS Applied Materials & Interfaces 13, 46391-46405 (2021) |
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Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density Maximilian Middelkamp, Lisa Ruck, Christoph Krisp, Piotr Sumislawski, Behnam Mohammadi, Matthias Dottermusch, Valerie Meister, Lukas Küster, Hartmut Schlüter , Sabine Windhorst, Julia E. Neumann Acta Neuropathologica Communications 9, 185 (24 pp) (2021) |
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Multiplexed complexome profiling using tandem mass tags Sergio Guerrero-Castillo, Christoph Krisp, Katrin Küchler, Susanne Arnold, Hartmut Schlüter , Søren W. Gersting Biochimica et Biophysica Acta, Bioenergetics 1862, 148448 (2021) |
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Antibacterial activity of xylose-derived LpxC inhibitors - Synthesis, biological evaluation and molecular docking studies Alexander Dreger, Katharina Hoff, Oriana Agoglitta, Sven-Kevin Hotop, Mark Brönstrup, Peter Heisig, Johannes Kirchmair , Ralph Holl Bioorganic Chemistry 107, 104603 (15 pp) (2021) |
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SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design Vasundara Srinivasan, Hévila Brognaro, Prince R. Prabhu, Edmarcia Elisa de Souza, Sebastian Günther, Patrick Y. A. Reinke, Thomas J. Lane, Helen Ginn, Huijong Han, Wiebke Ewert, Janina Sprenger, Faisal H. M. Koua, Sven Falke, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Bruno Alves França, Mengying Wang, Angélica Luana C. Barra, Markus Perbandt , Martin Schwinzer, Christina Schmidt, Lea Brings, Kristina Lorenzen, Robin Schubert, Rafael Rahal Guaragna Machado, Erika Donizette Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Oleksandr Yefanov, Julia Lieske, Luca Gelisio, Martin Domaracky, Philipp Middendorf, Michael Groessler, Fabian Trost, Marina Galchenkova, Sofiane Saouane, Johanna Hakanpää, Markus Wolf, Dusan Turk, Arwen R. Pearson , Henry N. Chapman , Winfried Hinrichs, Carsten Wrenger, Alke Meents , Christian Betzel bioRxiv 468943, 47 pp (2021) |
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Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources Sophie C. Brandt, Hévila Brognaro, Arslan Ali, Bernhard Ellinger, Katharina Maibach, Martin Rühl, Carsten Wrenger, Hartmut Schlüter , Wilhelm Schäfer, Christian Betzel , Stefan Janssen, Martin Gand Biotechnology for Biofuels 14, 74 (22 pp) (2021) |
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Cysteine-Rich Angiogenic Inducer 61: Pro-Survival Function and Role as a Biomarker for Disseminating Breast Cancer Cells Kai Bartkowiak, Isabel Heidrich, Marcel Kwiatkowski, Tobias M. Gorges, Antje Andreas, Maria Geffken, Karl Verpoort, Volkmar Müller, Hartmut Schlüter , Klaus Pantel Cancers 13, 563 (27 pp) (2021) |
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DNA origami signposts for identifying proteins on cell membranes by electron cryotomography Emma Silvester, Benjamin Vollmer, Vojtech Pražák, Daven Vasishtan, Emily A. Machala, Catheryne Whittle, Susan Black, Jonathan Bath, Andrew J. Turberfield, Kay Grünewald , Lindsay A. Baker Cell 184, 1110-1121.e16 (2021) |
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Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A George E. Allen, Olesya O. Panasenko, Zoltan Villanyi, Marina Zagatti, Benjamin Weiss, Lucile Pagliazzo, Susanne Huch, Christine Polte, Szabolcs Zahoran, Christopher S. Hughes, Vicent Pelechano, Zoya Ignatova , Martine A. Collart Cell Reports 36, 109633 (2021) |
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Determination of the Wurtzite and Zincblende Fractions in II-VI Semiconductor Nanowires Philip Harder, Andreas Nielsen, Ann-Katrin Sassnau, Dennis Bonatz, Markus Perbandt , Tobias Kipp , Alf Mews Chemistry of Materials 33, 1061-1069 (2021) |
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Skin Quality - A Holistic 360° View: Consensus Results Kate Goldie, Martina Kerscher, Sabrina Guillen Fabi, Cyro Hirano, Marina Landau, Ting Song Lim , Heather Woolery-Lloyd, Kavita Mariwalla, Je-Young Park, Yana Yutskovskaya Clinical, Cosmetic and Investigational Dermatology 14, 643-654 (2021) |
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Consensus on the Use of Hyaluronic Acid Fillers from the Cohesive Polydensified Matrix Range: Best Practice in Specific Facial Indications Jani van Loghem, Sonja Sattler, Gabriela Casabona, Sebastian Cotofana, Sabrina Guillen Fabi, Kate Goldie, Uliana Gout, Martina Kerscher, Ting Song Lim , Carla de Sanctis Pecora, Gerhard Sattler, Ada Trindade de Almeida, Rungsima Wanitphakdeedecha, Philip Werschler, Tatjana Pavicic Clinical, Cosmetic and Investigational Dermatology 14, 1175-1199 (2021) |
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Complementing the pulp proteome via sampling with a picosecond infrared laser (PIRL) Yaghoup Feridouni Khamaneh, Parnian Kiani, R. J. Dwayne Miller, Hartmut Schlüter , Reinhard E. Friedrich Clinical Oral Investigations 25, 6757-6768 (2021) |
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Ästhetische Dermatologie - Neuentwicklungen und Sicherheitsaspekte (Esthetic dermatology - new developments and safety aspects) U. Wollina, Martina Kerscher Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 72, 373-374 (2021) |
| 151 |
Hautqualität und Möglichkeiten zur Hautqualitätsverbesserung (Skin quality and ways to improve skin quality) Martina Kerscher, Heike Buntrock Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 72, 375-383 (2021) |
| 150 |
Safety of Cohesive Polydensified Matrix Cross-Linked Hyaluronic Acid Volumizing Gel in Temporal Hollows and Cheeks: A Prospective, Open-Label, Postmarket Study Tatjana Pavicic, Gerhard Sattler, Welf Prager, Tanja Fischer, Gerd Gauglitz, Matthias Hofmann , Hanna Dersch, Shahbaz Riaz, Martina Kerscher Dermatologic Surgery 47, 1359-1364 (2021) |
| 149 |
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation Hanna Englert, Chandini Rangaswamy, Carsten Deppermann, Jan-Peter Sperhake, Christoph Krisp, Danny Schreier, Emma Gordon, Sandra Konrath, Munif Haddad, Giordano Pula, Reiner K. Mailer, Hartmut Schlüter , Stefan Kluge, Florian Langer, Klaus Püschel, Kosta Panousis, Evi X. Stavrou, Coen Maas, Thomas Renné, Maike Frye EBioMedicine 67, 103382 (9 pp) (2021) |
| 148 |
Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation Namit Ranjan, Agnieszka A. Pochopien, Colin Chih-Chien Wu, Bertrand Beckert, Sandra Blanchet, Rachel Green, Marina V. Rodnina, Daniel N. Wilson EMBO Journal 40, e106449 (20 pp) (2021) |
| 147 |
Lactate metabolism in strictly anaerobic microorganisms with a soluble NAD+-dependent L-lactate dehydrogenase Florian P. Rosenbaum, Anja Poehlein, Richard Egelkamp, Rolf Daniel, Sönke Harder, Hartmut Schlüter , Marie Charlotte Schoelmerich Environmental Microbiology 23, 4661-4672 (2021) |
| 146 |
Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9 Ellen Gattkowski, Trevor J. Rutherford, Franziska Möckl, Andreas Bauche, Simon Sander, Ralf Fliegert, Henning Tidow FEBS Journal 288, 6769-6782 (2021) |
| 145 |
Structural Dynamics and Perspectives of Vitamin B6 Biosynthesis Enzymes in Plasmodium: Advances and Open Questions Angélica Luana C. Barra, Najeeb Ullah, Luana G. Morão, Carsten Wrenger, Christian Betzel , Alessandro S. Nascimento Frontiers in Cellular and Infection Microbiology 11, 688380 (11 pp) (2021) |
| 144 |
Editorial: From Apicomplexan Genes to Drug Discovery Gerhard Wunderlich, Christian Betzel , Carsten Wrenger Frontiers in Cellular and Infection Microbiology 11, 798754 (2 pp) (2021) |
| 143 |
Inefficient
placental virus replication and absence of neonatal cell-specific immunity upon Sars-CoV-2infection during pregnancy Ann-Christin Tallarek, Christopher Urbschat, Luis Fonseca Brito, Stephanie Stanelle-Bertram, Susanne Krasemann, Giada Frascaroli, Kristin Thiele, Agnes Wieczorek, Nadine Felber, Marc Lütgehetmann, Udo R. Markert, Kurt Hecher, Wolfram Brune , Felix R. Stahl, Gülsah Gabriel, Anke Diemert, Petra C. Arck Frontiers in Immunology 12, 698578 (2021) |
| 142 |
Ribosome Rescue Pathways in Bacteria Claudia Müller, Caillan Crowe-McAuliffe, Daniel N. Wilson Frontiers in Microbiology 12, 652980 (20 pp) (2021) |
| 141 |
Neuroserpin Is Strongly Expressed in the Developing and Adult Mouse Neocortex but Its Absence Does Not Perturb Cortical Lamination and Synaptic Proteome Dilara Kement, Rebecca Reumann, Katrin Schostak, Hannah Voß, Sara Douceau, Matthias Dottermusch, Michaela Schweizer, Hartmut Schlüter , Denis Vivien, Markus Glatzel, Giovanna Galliciotti Frontiers in Neuroanatomy 15, 627896 (18 pp) (2021) |
| 140 |
Proteins Binding to the Carbohydrate HNK-1: Common Origins? Gaston Castillo, Ralf Kleene, Melitta Schachner, Gabriele Loers, Andrew E. Torda International Journal of Molecular Sciences 22, 8116 (11 pp) (2021) |
| 139 |
Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane Jan Knop, Tim Lienemann, Haifa El Kilani, Sven Falke, Catharina Krings, Maria Sindalovskaya, Johannes Bergler, Christian Betzel , Stefan Hoth International Journal of Molecular Sciences 22, 9455 (19 pp) (2021) |
| 138 |
Viral Induced Protein Aggregation: A Mechanism of Immune Evasion Elena Muscolino, Laura-Marie Luoto, Wolfram Brune International Journal of Molecular Sciences 22, 9624 (16 pp) (2021) |
| 137 |
Tissue Sampling and Homogenization in the Sub-Microliter Scale with a Nanosecond Infrared Laser (NIRL) for Mass Spectrometric Proteomics Jan Hahn, Manuela Moritz, Hannah Voß, Penelope Pelczar, Samuel Huber , Hartmut Schlüter International Journal of Molecular Sciences 22, 10833 (15 pp) (2021) |
| 136 |
Investigation of the Proteomes of the Truffles Tuber albidum pico, T. aestivum, T. indicum, T. magnatum, and T. melanosporum Dennis Krösser, Benjamin Dreyer, Bente Siebels, Hannah Voß, Christoph Krisp, Hartmut Schlüter International Journal of Molecular Sciences 22, 12999 (16 pp) (2021) |
| 135 |
Human Adenovirus Type 5 Infection Leads to Nuclear Envelope Destabilization and Membrane Permeability Independently of Adenovirus Death Protein Søren Pfitzner, Jens B. Bosse, Helga Hofmann-Sieber, Felix Flomm, Rudolph Reimer, Thomas Dobner , Kay Grünewald , Linda E. Franken International Journal of Molecular Sciences 22, 13034 (22 pp) (2021) |
| 134 |
Release of the model drug SR101 from polyurethane nanocapsules in porcine hair follicles triggered by LED-derived low dose UVA light Loris Busch, Yuri Avlasevich, Paula Zwicker, Gisela Thiede, Katharina Landfester, Cornelia M. Keck, Martina C. Meinke, Maxim E. Darvin, Axel Kramer, Gerald Müller, Martina Kerscher, Jürgen Lademann, Alexa Patzelt International Journal of Pharmaceutics 597, 120339 (2021) |
| 133 |
Fixed-target serial femtosecond crystallography using in cellulo grown microcrystals Janine Mia Lahey-Rudolph, Robert Schönherr, Miriam Barthelmeß , Pontus Fischer, Carolin Seuring , Armin Wagner, Alke Meents , Lars Redecke IUCrJ 8, 665-677 (2021) |
| 132 |
The XBI BioLab for life science experiments at the European XFEL Huijong Han, Ekaterina Round, Robin Schubert, Yasmin Gül, Jana Makroczyova, Domingo Meza, Philipp Heuser, Martin Aepfelbacher , Imrich Barák, Christian Betzel , Petra Fromme, Inari Kursula, Poul Nissen, Elena Tereschenko, Joachim Schulz, Charlotte Uetrecht, Jozef Ulicny, Matthias Wilmanns, Janos Hajdu, Victor S. Lamzin, Kristina Lorenzen Journal of Applied Crystallography 54, 7-21 (2021) |
| 131 |
Development and validation of a global photonumeric scale for evaluating skin quality of aged female facial skin Christine Eiben-Nielson, Martina Kerscher Journal of Cosmetic Dermatology 20, 4032-4039 (2021) |
| 130 |
Skin anti-aging benefits of a 2% resveratrol emulsion Anke Schulte to Brinke, Ciska Janssens-Böcker, Martina Kerscher Journal of Cosmetics, Dermatological Sciences and Applications 11, 155-168 (2021) |
| 129 |
Cell-Free Blood Cell Secretome (BCS) Counteracts Skin Aging and Restores Firmness and Elasticity Martina Kerscher, Dominique Hertz-Kleptow, Attyla Drabik, Tanju Kaptan, Julio Reinecke Journal of Drugs in Dermatology 20, 682-688 (2021) |
| 128 |
IncobotulinumtoxinA Demonstrates Safety and Prolonged Duration of Effect in a Dose-Ranging Study for Glabellar Lines Martina Kerscher, Sabrina Fabi, Tanja Fischer, Michael Gold, John Joseph, Welf Prager, Berthold Rzany, Steve Yoelin, Susanna Roll, Gudrun Klein, Corey Maas Journal of Drugs in Dermatology 20, 1052-1060 (2021) |
| 127 |
Comparative Analysis of Different N-glycan Preparation Approaches and Development of Optimized Solid-Phase Permethylation Using Mass Spectrometry Yudong Guan, Min Zhang, Jigang Wang, Hartmut Schlüter Journal of Proteome Research 20, 2914-2922 (2021) |
| 126 |
An Integrated Strategy Reveals Complex Glycosylation of Erythropoietin Using Mass Spectrometry Yudong Guan, Min Zhang, Manasi Gaikwad, Hannah Voß, Ramin Fazel, Samira Ansari, Huali Shen, Jigang Wang, Hartmut Schlüter Journal of Proteome Research 20, 3654-3663 (2021) Erratum: Journal of Proteome Research 21, 2552-2552 (2022) |
| 125 |
Identifying Circulating Urotensin II and Urotensin II-Related Peptide-Generating Enzymes in the Human Plasma Fraction Cohn IV-4 Raphael Schuster, Pascal Steffen, Benjamin Dreyer, Sascha Rohn , Hartmut Schlüter , Maria Riedner Journal of Proteome Research 20, 5368-5378 (2021) |
| 124 |
Structure and dynamics of UBA5-UFM1 complex formation showing new insights in the UBA5 activation mechanism Sebastian Fuchs, Alexey G. Kikhney, Robin Schubert, Charlotte Kaiser, Eva Liebau, Dmitri I. Svergun, Christian Betzel , Markus Perbandt Journal of Structural Biology 213, 107796 (2021) |
| 123 |
Viral-mediated tethering to SEL1L facilitates endoplasmic reticulum-associated degradation of IRE1 Florian Hinte, Jendrik Müller, Wolfram Brune Journal of Virology 95, e01990-20 (2021) |
| 122 |
The Effect of Synonymous Single-Nucleotide Polymorphisms on an Atypical Cystic Fibrosis Clinical Presentation Giovana B. Bampi, Anabela S. Ramalho, Leonardo A. Santos, Johannes Wagner, Lieven Dupont, Harry Cuppens, Kris de Boeck, Zoya Ignatova Life 11, 14 (9 pp) (2021) |
| 121 |
Physicochemical Properties of Injectable Hyaluronic Acid: Skin Quality Boosters Linda Kleine-Börger , Alexander Kalies, Robert S. A. Meyer, Martina Kerscher Macromolecular Materials and Engineering 306, 2100134 (13 pp) (2021) |
| 120 |
Sample Displacement Batch Chromatography of Proteins Laura Heikaus, Siti Nurul Hidayah , Manasia Gaikwad, Marta Kotasinska, Verena Richter, Marcel Kwiatkowski, Hartmut Schlüter Methods in Molecular Biology 2178 (Protein Downstream Processing) 285-299 (2021) |
| 119 |
Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass Arslan Ali, Bernhard Ellinger, Sophie C. Brandt, Christian Betzel , Martin Rühl, Carsten Wrenger, Hartmut Schlüter , Wilhelm Schäfer, Hévila Brognaro, Martin Gand Microorganisms 9, 1581 (25 pp) (2021) |
| 118 |
Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP Caillan Crowe-McAuliffe, Hiraku Takada, Victoriia Murina, Christine Polte, Sergo Kasvandik, Tanel Tenson, Zoya Ignatova , Gemma C. Atkinson, Daniel N. Wilson , Vasili Hauryliuk Molecular Cell 81, 115-126.e7 (2021) |
| 117 |
Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD Joel Fauser, Burak Gulen, Vivian Pogenberg, Christian Pett, Danial Pourjafar-Dehkordi, Christoph Krisp, Dorothea Höpfner, Gesa König, Hartmut Schlüter , Matthias J. Feige, Martin Zacharias, Christian Hedberg, Aymelt Itzen Nature Communications 12, 2426 (14 pp) (2021) |
| 116 |
Context-specific action of macrolide antibiotics on the eukaryotic ribosome Maxim S. Svetlov, Timm O. Koller , Sezen Meydan, Vaishnavi Shankar, Dorota Klepacki, Norbert Polacek, Nicholas R. Guydosh, Nora Vázquez-Laslop, Daniel N. Wilson , Alexander S. Mankin Nature Communications 12, 2803 (14 pp) (2021) |
| 115 |
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens Caillan Crowe-McAuliffe, Victoriia Murina, Kathryn J. Turnbull , Marje Kasari, Merianne Mohamad, Christine Polte, Hiraku Takada, Karolis Vaitkevicius, Jörgen Johansson, Zoya Ignatova , Gemma C. Atkinson, Alex J. O'Neill, Vasili Hauryliuk, Daniel N. Wilson Nature Communications 12, 3577 (14 pp) (2021) |
| 114 |
Repurposing tRNAs for nonsense suppression Suki Albers , Bertrand Beckert, Marco C. Matthies, Chandra Sekhar Mandava, Raphael Schuster, Carolin Seuring , Maria Riedner , Suparna Sanyal, Andrew E. Torda , Daniel N. Wilson , Zoya Ignatova Nature Communications 12, 3850 (10 pp) (2021) |
| 113 |
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics Bertrand Beckert, Elodie C. Leroy, Shanmugapriya Sothiselvam, Lars V. Bock, Maxim S. Svetlov, Michael Graf, Stefan Arenz, Maha Abdelshahid, Britta Seip, Helmut Grubmüller, Alexander S. Mankin, C. Axel Innis, Nora Vázquez-Laslop, Daniel N. Wilson Nature Communications 12, 4466 (15 pp) (2021) |
| 112 |
Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity Tomas Kouba, Dominik Vogel, Sigurdur R. Thorkelsson, Emmanuelle R. J. Quemin, Harry M. Williams, Morlin Milewski, Carola Busch, Stephan Günther , Kay Grünewald , Maria Rosenthal, Stephen Cusack Nature Communications 12, 7018 (18 pp) (2021) |
| 111 |
Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification Cecile L. Maire, Marceline Manka Fuh, Kerstin Kaulich, Krystian D. Fita, Ines Stevic, Dieter H. Heiland, Joshua A. Welsh, Jennifer C. Jones, André Görgens, Tammo Ricklefs, Lasse Dührsen, Thomas Sauvigny, Simon A. Joosse, Guido Reifenberger, Klaus Pantel, Markus Glatzel, Andras G. Miklosi, James H. Felce, Marco Caselli, Valerio Pereno, Rudolph Reimer, Hartmut Schlüter , Manfred Westphal, Ulrich Schüller, Katrin Lamszus, Franz L. Ricklefs Neuro-Oncology 23, 1087-1099 (2021) |
| 110 |
Estimation of peptide elongation times from ribosome profiling spectra Michael Y. Pavlov, Gustaf Ullman, Zoya Ignatova , Måns Ehrenberg Nucleic Acids Research 49, 5124-5142 (2021) |
| 109 |
RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system Hiraku Takada, Caillan Crowe-McAuliffe, Christine Polte, Zhanna Yu Sidorova, Victoriia Murina, Gemma C. Atkinson, Andrey L. Konevega, Zoya Ignatova , Daniel N. Wilson , Vasili Hauryliuk Nucleic Acids Research 49, 8355-8369 (2021) |
| 108 |
Constraints on error rate revealed by computational study of G|U tautomerization in translation Andriy Kazantsev, Zoya Ignatova Nucleic Acids Research 49, 11823-11833 (2021) |
| 107 |
smORFer: a modular algorithm to detect small ORFs in prokaryotes Alexander Bartholomäus, Baban Kolte, Ayten Mustafayeva, Ingrid Goebel, Stephan Fuchs, Dirk Benndorf, Susanne Engelmann, Zoya Ignatova Nucleic Acids Research 49, e89 (12 pp) (2021) |
| 106 |
Facial Skin Revitalization with Cohesive Polydensified Matrix-HA20G: Results from a Randomized Multicenter Clinical Study Martina Kerscher, Welf Prager, Tanja C. Fischer, Gerd G. Gauglitz, Tatjana Pavicic, Ulrich Kühne, Maria Kravtsov, Matthias Hofmann , Hanna Dersch, Sonja Sattler Plastic and Reconstructive Surgery. Global Open 9, e3973 (9 pp) (2021) |
| 105 |
Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach Stephan Fuchs, Martin Kucklick, Erik Lehmann, Alexander Beckmann, Maya Wilkens, Baban Kolte, Ayten Mustafayeva, Tobias Ludwig, Maurice Diwo, Josef Wissing, Lothar Jänsch, Christian H. Ahrens, Zoya Ignatova , Susanne Engelmann PLoS Genetics 17, e1009585 (2021) |
| 104 |
Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc Erik I. Hallin, Sigurbjörn Markússon, Lev Böttger, Andrew E. Torda , Clive R. Bramham, Petri Kursula PLoS One 16, e0251459 (26 pp) (2021) |
| 103 |
GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi Jessica Rauch, Jessica Barton, Marcel Kwiatkowski, Malte Wunderlich, Pascal Steffen, Kristin Moderzynski, Stefanie Papp, Katharina Höhn, Hella Schwanke, Susanne Witt, Ulricke Richardt, Ute Mehlhoop, Hartmut Schlüter , Verena Pianka, Bernhard Fleischer, Dennis Tappe, Anke Osterloh PLoS One 16, e0253084 (31 pp) (2021) |
| 102 |
Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity Robert Rauscher, Giovana B. Bampi, Marta Guevara-Ferrer, Leonardo A. Santos, Disha Joshi, David Mark, Lisa J. Strug, Johanna M. Rommens, Manfred Ballmann, Eric J. Sorscher, Kathryn E. Oliver, Zoya Ignatova Proceedings of the National Academy of Sciences of the United States of America 118, e2010612118 (2021) |
| 101 |
Structure of Gcn1 bound to stalled and colliding 80S ribosomes Agnieszka A. Pochopien, Bertrand Beckert, Sergo Kasvandik, Otto Berninghausen, Roland Beckmann, Tanel Tenson, Daniel N. Wilson Proceedings of the National Academy of Sciences of the United States of America 118, e2022756118 (8 pp) (2021) |
| 100 |
Structural insights into a novel family of integral membrane siderophore reductases Inokentijs Josts, Katharina Veith, Vincent Normant, Isabelle J. Schalk, Henning Tidow Proceedings of the National Academy of Sciences of the United States of America 118, e2101952118 (7 pp) (2021) |
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Computational
models in the service of X-ray and cryo-electron microscopy structure determination Andriy Kryshtafovych, John Moult, Reinhard Albrecht, Geoffrey A. Chang, Kinlin Chao, Alec Fraser, Julia Greenfield, Marcus D. Hartmann, Osnat Herzberg, Inokentijs Josts, Petr G. Leiman, Sara B. Linden, Andrei N. Lupas, Daniel C. Nelson, Steven D. Rees, Xiaoran Shang, Maria L. Sokolova, Henning Tidow Proteins: Structure, Function, and Bioinformatics 89, 1633-1646 (2021) |
| 98 |
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease Sebastian Günther, Patrick Y. A. Reinke, Yaiza Fernández-García, Julia Lieske, Thomas J. Lane, Helen M. Ginn, Faisal H. M. Koua, Christiane Ehrt, Wiebke Ewert, Dominik Oberthür , Oleksandr Yefanov, Susanne Meier, Kristina Lorenzen, Boris Krichel, Janine-Denise Kopicki, Luca Gelisio, Wolfgang Brehm, Ilona Dunkel, Brandon Seychell, Henry Gieseler, Brenna Norton-Baker, Beatriz Escudero-Pérez, Martin Domaracky, Sofiane Saouane, Aleksandra Tolstikova , Thomas A. White , Anna Hänle, Michael Groessler, Holger Fleckenstein, Fabian Trost, Marina Galchenkova, Yaroslav Gevorkov, Chufeng Li, Salah Awel, Ariana Peck, Miriam Barthelmeß , Frank Schluenzen, Paulraj Lourdu Xavier, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Sven Falke, Vasundara Srinivasan, Bruno Alves França, Martin Schwinzer, Hévila Brognaro, Cromarte Rogers, Diogo Melo, Joanna J. Zaitseva-Doyle, Juraj Knoška, Gisel E. Peña-Murillo, Aida Rahmani Mashhour, Vincent Hennicke, Pontus Fischer, Johanna Hakanpää, Jan Meyer, Philip Gribbon, Bernhard Ellinger, Maria Kuzikov, Markus Wolf, Andrea R. Beccari, Gleb Bourenkov, David von Stetten, Guillaume Pompidor, Isabel Bento, Saravanan Panneerselvam, Ivars Karpics, Thomas R. Schneider, Maria M. Garcia-Alai , Stephan Niebling, Christian Günther, Christina Schmidt, Robin Schubert, Huijong Han, Juliane Boger, Diana C. F. Monteiro, Linlin Zhang, Xinyuanyuan Sun, Jonathan Pletzer-Zelgert, Jan Wollenhaupt, Christian G. Feiler, Manfred S. Weiss, Eike-Christian Schulz, Pedram Mehrabi, Katarina Karnicar, Aleksandra Usenik, Jure Loboda, Henning Tidow , Ashwin Chari, Rolf Hilgenfeld, Charlotte Uetrecht, Russell Cox, Andrea Zaliani, Tobias Beck , Matthias Rarey , Stephan Günther , Dusan Turk, Winfried Hinrichs, Henry N. Chapman , Arwen R. Pearson , Christian Betzel , Alke Meents Science 372, 642-646 (2021) |
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tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase Amila Zuko, Moushami Mallik, Robin Thompason, Emily L. Spaulding, Anne R. Wienand, Marlje Been, Abigail L. D. Tadenev, Nick van Bakel, Celine Sijlmans, Leonardo A. Santos, Julia Bussmann, Marica Catinozzi, Sarada Das, Divita Julshrestha, Robert W. Burgess, Zoya Ignatova , Erik Storkebaum Science 373, 1161-1166 (2021) |
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HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation Hannes G. Roggenkamp, Imrankhan Khansahib, Lola Hernandez, Yunpeng Zhang, Dmitri Lodygin, Aileen Krüger, Feng Gu, Franziska Möckl, Anke Löhndorf, Valerie Wolters, Daniel Woike, Anette Rosche, Andreas Bauche, Daniel Schetelig, René Werner, Hartmut Schlüter , Antonio V. Failla, Chris Meier , Ralf Fliegert, Timothy F. Walseth, Alexander Flügel, Björn-Philipp Diercks, Andreas H. Guse Science Signaling 14 (12 pp) 675 (2021) |
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FoldAffinity: binding affinities from nDSF experiments Stephan Niebling, Osvaldo Burastero, Jérôme Bürgi, Christian Günther, Lucas A. Defelipe, Simon Sander, Ellen Gattkowski, Raghavendra Anjanappa, Matthias Wilmanns, Sebastian Springer, Henning Tidow , Maria M. Garcia-Alai Scientific Reports 11, 9572 (17 pp) (2021) |
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The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity Nadine Werner, Katrin Petersen, Christel Vollstedt, Pablo Perez Garcia, Jennifer Chow, Manuel Ferrer, Laura Fernandez-Lopez, Sven Falke, Markus Perbandt , Winfried Hinrichs, Christian Betzel , Wolfgang R. Streit Scientific Reports 11, 12255 (14 pp) (2021) |
| 93 |
Eruca sativa seed napin structural insights and thorough functional characterization Binish Khaliq, Sven Falke, Qamar Saeed, Muhammad Bilal, Aisha Munawar, Arslan Ali, Gunnar Baermann, Habib-ur-Rehman Athar, Seema Mahmood, Christian Betzel , Qurban Ali, Ahmed Akrem Scientific Reports 11, 24066 (2021) |
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Cell Fusion and Syncytium Formation in Betaherpesvirus Infection Jiajia Tang, Giada Frascaroli, Xuan Zhou, Jan Knickmann, Wolfram Brune Viruses 13, 1973 (19 pp) (2021) |
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Species-Specific Inhibition of Necroptosis by HCMV UL36 Elena Muscolino, Claudia Castiglioni, Renke Brixel, Giada Frascaroli, Wolfram Brune Viruses 13, 2134 (15 pp) (2021) |
| 90 |
Mechanism of drug resistance in Staphylococcus aureus and future drug discovery Felipe Wakasuqui, Ana Leticia Gori Lusa, Sven Falke, Christian Betzel , Carsten Wrenger Jenny Stanford Series on Biocatalysis 7, 259-280 (2021) |
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Chapter 11 - Correlative super-resolution fluorescence and electron cryo-microscopy based on cryo-SOFI Vojtech Pražák, Kay Grünewald , Rainer Kaufmann Methods in Cell Biology 162, 253-271 (2021) |
| 88 |
Sample Displacement Batch Chromatography of Proteins Marta Kotasinska, Verena Richter, Marcel Kwiatkowski, Hartmut Schlüter -/- Editor: Nikolaos E. Labrou Methods in Molecular Biology 2178 (Protein Downstream Processing) 285-299 (2021) |
| 87 |
Characterizing Genetic Parts and Devices Using RNA Sequencing Deepti Vipin, Zoya Ignatova , Thomas E. Gorochowski Methods in Molecular Biology 2229 (Synthetic Gene Circuits) 175-187 (2021) |
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Codon Resolution Analysis of Ribosome Profiling Data Alexander Bartholomäus, Zoya Ignatova -/- Editor: Vyacheslav M. Labunskyy Methods in Molecular Biology 2252 (Ribosome Profiling) 251-268 (2021) |
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In Vitro Viral Evolution Identifies a Critical Residue in the Alphaherpesvirus Fusion Glycoprotein B Ectodomain That Controls gH/gL-Independent Entry Melina Vallbracht, Henriette Lötzsch, Barbara G. Klupp, Walter Fuchs, Benjamin Vollmer, Kay Grünewald , Marija Backovic, Felix A. Rey, Thomas C. Mettenleiter Molecular and Cellular Biology 12, e00557-21 (2021) |
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The Ribosome and Protein Synthesis Paul Huter, Michael Graf, Daniel N. Wilson -/- Editors: Sabine Müller, Benoît Masquida, Wade Winkler Ribozymes 2, 193-226 (2021) |
2020 | |
| 83 |
Nocardamine-Dependent Iron Uptake in Pseudomonas aeruginosa: Exclusive Involvement of the FoxA Outer Membrane Transporter Vincent Normant, Inokentijs Josts, Lauriane Kuhn, Quentin Perraud, Sarah Fritsch, Philippe Hammann, Gaëtan L. A. Mislin, Henning Tidow , Isabelle J. Schalk ACS Chemical Biology 15, 2741-2751 (2020) |
| 82 |
Liquid Formulation of Abobotulinumtoxin A: A 6-Month, Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of a Single Treatment, Ready-to-Use Toxin for Moderate-to-Severe Glabellar Lines Benjamin Ascher, Berthold Rzany, Philippe Kestemont, Said Hilton, Marc Heckmann, Isaac Bodokh, Ernst Magnus Noah, Dominique Boineau, Martina Kerscher, Magali Volteau, Philippe Le Berre, Philippe Picaut Aesthetic Surgery Journal 40, 93-104 (2020) Erratum: Aesthetic Surgery Journal sjab111 (2021) |
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Significantly Increased Patient Satisfaction Following Liquid Formulation Abobotulinumtoxin A Treatment in Glabellar Lines: FACE-Q Outcomes From a Phase 3 Clinical Trial Benjamin Ascher, Berthold Rzany, Philippe Kestemont, Said Hilton, Marc Heckmann, Isaac Bodokh, Ernst Magnus Noah, Dominique Boineau, Martina Kerscher, Magali Volteau, Philippe Le Berre, Philippe Picaut Aesthetic Surgery Journal 40, 1000-1008 (2020) |
| 80 |
Response to "Facial Line Outcomes (FLO-11) and Facial Line Satisfaction Questionnaire (FLSQ) Meet FDA PRO Guidance" Benjamin Ascher, Berthold Rzany, Philippe Kestemont, Said Hilton, Marc Heckmann, Isaac Bodokh, Ernst Magnus Noah, Dominique Boineau, Martina Kerscher, Magali Volteau, Philippe Le Berre, Philippe Picaut Aesthetic Surgery Journal 40, NP710-NP711 (2020) |
| 79 |
Lipidomic profiling of virus infection identifies mediators that resolve herpes simplex virus-induced corneal inflammatory lesions Cuiping Zhang, Zuojian Hu, Ke Wang, Lujie Yang, Yue Li, Hartmut Schlüter , Pengyuan Yang, Jiaxu Hong, Hongxiu Yu Analyst 145, 3967-3976 (2020) |
| 78 |
Boronic acid-functionalized mesoporous magnetic particles with a hydrophilic surface for the multimodal enrichment of glycopeptides for glycoproteomics Lujie Yang, Quanqing Zhang, Yuanyu Huang, Ling Lin, Hartmut Schlüter , Ke Wang, Cuiping Zhang, Pengyuan Yang, Hongxiu Yu Analyst 145, 5252-5259 (2020) |
| 77 |
Cellular Electron Cryo-Tomography to Study Virus-Host Interactions Emmanuelle R. J. Quemin, Emily A. Machala, Benjamin Vollmer, Vojtech Pražák, Daven Vasishtan, Rene Rosch, Michael Grange, Linda E. Franken, Lindsay A. Baker, Kay Grünewald Annual Review of Virology 7, 239-262 (2020) |
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Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease Sebastian Günther, Patrick Y. A. Reinke, Dominik Oberthür , Oleksandr Yefanov, Helen Ginn, Susanne Meier, Thomas J. Lane, Kristina Lorenzen, Luca Gelisio, Wolfgang Brehm, Illona Dunkel, Martin Domaracky, Sofiane Saouane, Julia Lieske, Christiane Ehrt, Faisal H. M. Koua, Aleksandra Tolstikova , Thomas A. White , Michael Groessler, Holger Fleckenstein, Fabian Trost, Marina Galchenkova, Yaroslav Gevorkov, Chufeng Li, Salah Awel, Ariana Peck, P. Lourdu Xavier, Miriam Barthelmeß , Frank Schluenzen, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Sven Falke, Bruno Alves França, Martin Schwinzer, Hévila Brognaro, Brandon Seychell, Henry Gieseler, Diogo Melo, Jo J. Zaitsev-Doyle, Brenna Norton-Baker, Juraj Knoška, Gisel Esperanza, Aida Rahmani Mashhour, Filip Guicking, Vincent Hennicke, Pontus Fischer, Cromarte Rogers, Diana C. F. Monteiro, Johanna Hakanpää, Jan Meyer, Heshmat Noei, Phil Gribbon, Bernhard Ellinger, Maria Kuzikov, Markus Wolf, Linlin Zhang, Xinyuanyuan Sun, Jonathan Pletzer-Zelgert, Jan Wollenhaupt, Christian Feiler, Manfred Weiss, Eike-Christian Schulz, Pedram Mehrabi, Christina Schmidt, Robin Schubert, Huijong Han, Boris Krichel, Yaiza Fernández-García, Beatriz Escudero-Pérez, Stephan Günther , Dusan Turk, Charlotte Uetrecht, Tobias Beck , Henning Tidow , Ashwin Chari, Andrea Zaliani, Matthias Rarey , Russell Cox, Rolf Hilgenfeld, Henry N. Chapman , Arwen R. Pearson , Christian Betzel , Alke Meents bioRxiv 043554 (17 pp) (2020) |
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eEF3 promotes late stages of tRNA translocation on the ribosome Namit Ranjan, Agnieszka A. Pochopien, Colin Chih-Chien Wu, Bertrand Beckert, Sandra Blanchet, Rachel Green, Marina V. Rodnina, Daniel N. Wilson bioRxiv 182105 (2020) |
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Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease Sebastian Günther, Patrick Y. A. Reinke, Yaiza Fernández-García, Julia Lieske, Thomas J. Lane, Helen M. Ginn, Faisal H. M. Koua, Christiane Ehrt, Wiebke Ewert, Dominik Oberthür , Oleksandr Yefanov, Susanne Meier, Kristina Lorenzen, Boris Krichel, Janine-Denise Kopicki, Luca Gelisio, Wolfgang Brehm, Ilona Dunkel, Brandon Seychell, Henry Gieseler, Brenna Norton-Baker, Beatriz Escudero-Pérez, Martin Domaracky, Sofiane Saouane, Aleksandra Tolstikova , Thomas A. White , Anna Hänle, Michael Groessler, Holger Fleckenstein, Fabian Trost, Marina Galchenkova, Yaroslav Gevorkov, Chufeng Li, Salah Awel, Ariana Peck, Miriam Barthelmeß , Frank Schluenzen, P. Lourdu Xavier, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Sven Falke, Vasundara Srinivasan, Bruno Alves França, Martin Schwinzer, Hévila Brognaro, Cromarte Rogers, Diogo Melo, Jo J. Zaitsev-Doyle, Juraj Knoška, Gisel E. Peña Murillo, Aida Rahmani Mashhour, Filip Guicking, Vincent Hennicke, Pontus Fischer, Johanna Hakanpää, Jan Meyer, Phil Gribbon, Bernhard Ellinger, Maria Kuzikov, Markus Wolf, Andrea R. Beccari, Gleb Bourenkov, David von Stetten, Guillaume Pompidor, Isabel Bento, Saravanan Panneerselvam, Ivars Karpics, Thomas R. Schneider, Maria M. Garcia-Alai , Stephan Niebling, Christian Günther, Christina Schmidt, Robin Schubert, Huijong Han, Juliane Boger, Diana C. F. Monteiro, Linlin Zhang, Xinyuanyuan Sun, Jonathan Pletzer-Zelgert, Jan Wollenhaupt, Christian G. Feiler, Manfred S. Weiss, Eike-Christian Schulz, Pedram Mehrabi, Katarina Karnicar, Aleksandra Usenik, Jure Loboda, Henning Tidow , Ashwin Chari, Rolf Hilgenfeld, Charlotte Uetrecht, Russell Cox, Andrea Zaliani, Tobias Beck , Matthias Rarey , Stephan Günther , Dusan Turk, Winfried Hinrichs, Henry N. Chapman , Arwen R. Pearson , Christian Betzel , Alke Meents bioRxiv 378422v2, 36 pp (2020) |
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Defective NETs clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation Hanna Englert, Chandini Rangaswamy, Carsten Deppermann, Jan-Peter Sperhake, Christoph Krisp, Danny Schreier, Emma Gordon, Sandra Konrath, Munif Haddad, Giordano Pula, Reiner K. Mailer, Hartmut Schlüter , Florian Langer, Klaus Püschel, Kosta Panousis, Evi X. Stavrou, Coen Maas, Thomas Renné, Maike Frye bioRxiv 424644v1, 19 pp (2020) |
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Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells Tamara Fernández-Calero, Marcos Davyt, Karen Perelmuter, Cora Chalar, Giovana Bampi, Helena Persson, Juan Pablo Tosar, Völundur Hafstað, Hugo Naya, Carlos Rovira, Mariela Bollati-Fogolín, Ricardo Ehrlich, Gilles Flouriot, Zoya Ignatova , Mónica Marín Cancer & Metabolism 8, 8 (20 pp) (2020) |
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Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer Marcus Wurlitzer, Nikolaus Möckelmann, Malte Kriegs, Maren Vens, Maryam Omidi, Konstantin Hoffer, Clara von Bargen, Christina Möller-Koop, Melanie Witt, Conrad Droste, Agnes Oetting, Hannes Petersen, Chia-Jung Busch, Adrian Münscher, Hartmut Schlüter , Till Sebastian Clauditz, Thorsten Rieckmann Cancers 12, 1531 (2020) |
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tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation Irem Avcilar-Kucukgoze, Howard Gamper, Christine Polte, Zoya Ignatova , Ralph Krätzner, Michael Shtutman, Ya-Ming Hou, Dawei W. Dong, Anna Kashina Cell Chemical Biology 27, 839-849.e4 (2020) |
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Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection Swantje Thiele, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Martin Zickler, Martin Müller, Berfin Tuku, Patricia Resa-Infante, Debby van Riel, Malik Alawi, Thomas Günther, Franziska Rother, Stefanie Hüge, Susanne Reimering, Alice McHardy, Adam Grundhoff , Wolfram Brune , Albert Osterhaus, Michael Bader, Enno Hartmann, Gülsah Gabriel Cell Reports 31, 107549 (8 pp) (2020) |
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Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel Patrick Pausch, Maha Abdelshahid, Wieland Steinchen, Heinrich Schäfer, Fabio Lino Gratani, Sven-Andreas Freibert, Christiane Wolz, Kürsad Turgay, Daniel N. Wilson , Gert Bange Cell Reports 32, 108157 (19 pp) (2020) |
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FLASHDeconv: Ultrafast, High-Quality Feature Deconvolution for Top-Down Proteomics Kyowon Jeong, Jihyung Kim, Manasi Gaikwad, Siti Nurul Hidayah , Laura Heikaus, Hartmut Schlüter , Oliver Kohlbacher Cell Systems 10, 213-218.e6 (2020) |
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Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer Hannah Voß, Marcus Wurlitzer, Daniel J. Smit, Florian Ewald, Malik Alawi, Michael Spohn, Daniela Indenbirken, Maryam Omidi, Kerstin David, Hartmut Juhl, Ronald Simon, Guido Sauter, Lutz Fischer, Jakob R. Izbicki, Mark P. Molloy, Björn Nashan, Hartmut Schlüter , Manfred Jücker Clinical & Experimental Metastasis 37, 649-656 (2020) |
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Safety and Performance of Etermis 3 and 4 in Wrinkles/Folds Treatment and Facial Volume Enhancement: A Prospective, Evaluator-Blinded, Open-Label Study Gerhard Sattler, Martina Kerscher, Ernst Magnus Noah, Welf Prager, Tanja C. Fischer, Patricia Ogilvie, Matthias Hofmann , Hanna Dersch, Gemma Odena Clinical, Cosmetic and Investigational Dermatology 13, 591-599 (2020) |
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Protein-crystal detection with a compact multimodal multiphoton microscope Qing-di Cheng, Hsiang-Yu Chung, Robin Schubert, Shih-Hsuan Chia, Sven Falke, Celestin Nzanzu Mudogo, Franz X. Kärtner, Guoqing Chang, Christian Betzel Communications Biology 3, 569 (7 pp) (2020) |
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Herpesvirus membrane fusion - a team effort Benjamin Vollmer, Kay Grünewald Current Opinion in Structural Biology 62, 112-120 (2020) |
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Topische Behandlung von Pigmentstörungen mit kosmetischen und pharmazeutischen Wirkstoffen (Topical treatment of pigmentation disorders with cosmetic and pharmaceutical agents) Martina Kerscher, Heike Buntrock Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 71, 944-949 (2020) |
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Optimizing skin pharmacotherapy for older patients: the future is at hand but are we ready for it? Christian Hausmann, Annika Vogt, Martina Kerscher, Kamran Ghoreschi, Monika Schäfer-Korting, Christian Zoschke Drug Discovery Today 25, 851-861 (2020) |
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Repression of viral gene expression and replication by the unfolded protein response effector XBP1u Florian Hinte, Eelco van Anken, Boaz Tirosh, Wolfram Brune eLife 9, e51804 (2020) |
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Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria Kyle Mangano, Tanja Florin, Xinhao Shao, Dorota Klepacki, Irina Chelysheva, Zoya Ignatova , Yu Gao, Alexander S. Mankin, Nora Vázquez-Laslop eLife 9, e62655 (2020) |
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Xenograft-derived mRNA/miR and protein interaction networks of systemic dissemination in human prostate cancer Tobias Lange, Timur R. Samatov, Vladimir V. Galatenko, Pascal Steffen, Helge von Kriegstein, Tanja Spethmann, Daniel Wicklein, Hanna Maar, Kristine Kupfernagel, Vera Labitzky, Sandra Hanika, Sarah Starzonek, Ann-Kristin Ahlers, Kristoffer Riecken, Ronald Simon, Adam Polonski, Guido Sauter, Thorsten Schlomm, Hartwig Huland, Steven A. Johnsen, Hartmut Schlüter , Alexander G. Tonevitsky, Udo Schumacher European Journal of Cancer 137, 93-107 (2020) |
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Genetic and Functional Characterization of Toll-Like Receptor Responses in Immunocompetent Patients With CMV Mononucleosis Giada Frascaroli, Giada Rossini, Virginia Maltoni, Michele Bartoletti, Patrizia Ortolani, Sara Gredmark-Russ, Francesco Gelsomino, Alessandra Moroni, Silvia Silenzi, Gastone Castellani, Vittorio Sambri, Antonio Mastroianni, Wolfram Brune , Stefania Varani Frontiers in Cellular and Infection Microbiology 10, 386 (7 pp) (2020) |
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Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases Sophie C. Brandt, Bernhard Ellinger, Thuat van Nguyen, Sönke Harder, Hartmut Schlüter , Richard L. Hahnke, Martin Rühl, Wilhelm Schäfer, Martin Gand Frontiers in Microbiology 11, 2154 (16 pp) (2020) |
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The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted Ulf Birkedal, Henrik Nielsen, Bertrand Beckert, Daniel N. Wilson , Henrik Nielsen Frontiers in Microbiology 11, 582022 (11 pp) (2020) |
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Detection of doxorubicin, cisplatin and therapeutic antibodies in formalin-fixed paraffin-embedded human cancer cells Lukas Böckelmann, Christin Starzonek, Ann-Christin Niehoff, Uwe Karst, Jürgen Thomale, Hartmut Schlüter , Carsten Bokemeyer, Achim Aigner, Udo Schumacher Histochemistry and Cell Biology 153, 367-377 (2020) |
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Combined in vitro and in silico analyses of missense mutations in GNPTAB provide new insights into the molecular bases of mucolipidosis II and III α/β Tatyana Danyukova, Nataniel F. Ludwig, Renata Voltolini Velho, Frederike L. Harms, Nilay Günes, Henning Tidow , Ida V. Schwartz, Beyhan Tüysüz, Sandra Pohl Human Mutation 41, 133-139 (2020) |
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A
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Understanding Protein Networks using Vester's Sensitivity Model Moreno Liana Amaya, Maryam Omidi, Marcus Wurlitzer, Bérengère J. C. Luthringer, Heike Helmholz, Hartmut Schlüter , Regine Willumeit-Römer , Armin Fugenschuh IEEE/ACM Transactions on Computational Biology and Bioinformatics 17, 1440-1450 (2020) |
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Ablation Precision and Thermal Effects of a Picosecond Infrared Laser (PIRL) on Roots of Human Teeth: A Pilot Study Ex Vivo Reinhard E. Friedrich, Maria Quade, Nate Jowett, Peter Kroetz, Michael Amling, Jozef Zustin, Martin Gosau, Hartmut Schlüter , R. J. Dwayne Miller in vivo 34, 2325-2336 (2020) |
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OmixLitMiner: A Bioinformatics Tool for Prioritizing Biological Leads from 'Omics Data Using Literature Retrieval and Data Mining Pascal Steffen, Jemma Wu, Shubhang Hariharan, Hannah Voß, Vijay Raghunath, Mark P. Molloy, Hartmut Schlüter International Journal of Molecular Sciences 21, 1374 (11 pp) (2020) |
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The Tumor Suppressor TFF1 Occurs in Different Forms and Interacts with Multiple Partners in the Human Gastric Mucus Barrier: Indications for Diverse Protective Functions Jörn Heuer, Franziska Heuer, René Stürmer, Sönke Harder, Hartmut Schlüter , Nayara Braga Emidio, Markus Muttenthaler, Dörthe Jechorek, Frank Meyer, Werner Hoffmann International Journal of Molecular Sciences 21, 2508 (2020) |
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Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1-Pdx2 Complex Najeeb Ullah, Hina Andaleeb, Celestin Nzanzu Mudogo, Sven Falke, Christian Betzel , Carsten Wrenger International Journal of Molecular Sciences 21, 5971 (16 pp) (2020) |
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Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens Riccardo Sola, Mario Mardirossian, Bertrand Beckert, Laura Sanghez de Luna, Dennis Prickett, Alessandro Tossi, Daniel N. Wilson , Marco Scocchi International Journal of Molecular Sciences 21, 7367 (17 pp) (2020) |
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A fixed-target platform for serial femtosecond crystallography in a hydrated environment Megan L. Shelby, Deepshika Gilbile, Thomas D. Grant, Carolin Seuring , B. W. Segelke, Wei He, A. C. Evans, T. Pakendorf, P. Fischer, Mark S. Hunter, A. Batyuk, Miriam Barthelmeß , Alke Meents , Matthew A. Coleman, T. L. Kuhl, M. Frank IUCrJ 7, 30-41 (2020) |
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Novel approaches for the lipid sponge phase crystallization of the Rhodobacter sphaeroides photosynthetic reaction center Georgii Selikhanov, Tatiana Fufina, Lyudmila Vasilieva, Christian Betzel , Azat G. Gabdulkhakov IUCrJ 7, 1084-1091 (2020) |
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Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures Jerry Tan, Julieta Spada, Cecilia Orlandi, Martina Kerscher, Maryna Anfilova, Sonya Abdulla, Adriana Floriánová, Klaudia Preisz, Anita Altmayer, Catherine Delva, Delphine Kerob, Maiia Goldobina, Monika Arenbergerová, Svyatoslav Tuz, Elena Araviiskaia Journal of Cosmetic Dermatology 19, 682-688 (2020) |
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Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues Giovana B. Bampi, Robert Rauschera, Sebastian Kirchner, Kathryn E. Oliver, Marcel J. C. Bijvelds, Leonardo A. Santos, Johannes Wagner, Raymond A. Frizzell, Hugo R. de Jonge, Eric J. Sorscher, Zoya Ignatova Journal of Cystic Fibrosis 19, 1021-1026 (2020) |
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Incobotulinumtoxin A Demonstrates Safety and Prolonged Duration of Effect in a Dose-Ranging Study for Glabellar Lines Martina Kerscher, Sabrina Fabi, Tanja Fischer, Michael Gold, John Joseph, Welf Prager, Berthold Rzany, Steve Yoelin, Susanna Roll, Gudrun Klein, Corey Maas Journal of Drugs in Dermatology 19, 985-991 (2020) |
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Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells is associated with brain metastasis and alters exosome biogenesis Julia Arnold, Juliana Schattschneider, Christine Blechner, Christoph Krisp, Hartmut Schlüter , Michaela Schweizer, Marcus M. Nalaskowski, Leticia Oliveira-Ferrer, Sabine Windhorst Journal of Experimental & Clinical Cancer Research 39, 205 (15 pp) (2020) |
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Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake Santra Brenna, Hermann C. Altmeppen, Behnam Mohammadi, Björn Rissiek, Florence Schlink, Peter Ludewig, Christoph Krisp, Hartmut Schlüter , Antonio Virgilio Failla, Carola Schneider, Markus Glatzel, Berta Puig, Tim Magnus Journal of Extracellular Vesicles 9, 1809065 (21 pp) (2020) |
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Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice Neele Schumacher, Karsten Yan, Monja Gandraß, Miryam Müller, Christoph Krisp, Robert Häsler, Antonella Carambia, Jerzy-Roch Nofer, Joanna P. Bernardes, Mouhamad Khouja, Ilka Thomsen, Karel Chalupsky, Julia Bolik, Christoph Hölscher, Thomas Wunderlich, Johannes Herkel, Philip Rosenstiel, Christoph Schramm , Hartmut Schlüter , Thomas Renné, Hans-Willi Mittrücker , Stefan Rose-John, Dirk Schmidt-Arras Journal of Hepatology 74, 407-418 (2020) |
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Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens Mario Mardirossian, Riccardo Sola, Bertrand Beckert, Erica Valencic, Dominic W. P. Collis, Jure Borišek, Federica Armas, Adriana di Stasi, Jan Buchmann, Egor A. Syroegin, Yury S. Polikanov, Alessandra Magistrato, Kai Hilpert, Daniel N. Wilson , Marco Scocchi Journal of Medicinal Chemistry 63, 9590-9602 (2020) |
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Molecular characterization of a ghrelin-L-aptamer complex Christina Schmidt, Markus Perbandt , Sven Klussmann, Christian Betzel Journal of Molecular Structure 1204, 127510 (2020) |
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A bifunctional nitrone conjugated secondary metabolite targeting the ribosome Emilianne Limbrick, Michael Graf, Dagmara K Derewacz, Fabian Nguyen, Jeffrey M. Spraggins, Maximiliane Wieland, Audrey Ynigez-Gutierrez, Benjamin J Reisman, Boris Zinshteyn, Kathryn M. McCulloch, Tina M. Iverson, Rachel Green, Daniel N. Wilson , Brian O. Bachmann Journal of the American Chemical Society 142, 18369-18377 (2020) |
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Mass Spectrometric Lipid Profiles of Picosecond Infrared Laser-Generated Tissue Aerosols Discriminate Different Brain Tissues Marcus Wurlitzer, Elisabeth Hessling, Karsten Rinas, Marceline Manka Fuh, Hannes Petersen, Franz L. Ricklefs, Katrin Lamszus, Jan Regelsberger, Stephanie Maier, Sebastian Kruber, Nils-Owe Hansen, R. J. Dwayne Miller, Hartmut Schlüter Lasers in Surgery and Medicine 52, 228-234 (2020) |
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Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer Sergey A. Dyshlovoy, Dmitry N. Pelageev, Jessica Hauschild, Yurii E. Sabutskii, Ekaterina A. Khmelevskaya, Christoph Krisp, Moritz Kaune, Simone Venz, Ksenia L. Borisova, Tobias Busenbender, Vladimir A. Denisenko, Hartmut Schlüter , Carsten Bokemeyer, Markus Graefen, Sergey G. Polonik, Victor Ph. Anufriev, Gunhild von Amsberg Marine Drugs 18, 251 (31 pp) (2020) |
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A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism Henning Büttner, Markus Perbandt , Thomas Kohler, Alexey Kikhney, Manuel Wolters, Martin Christner, Marisol Heise, Jérôme Wilde, Samira Weißelberg, Anna Both, Christian Betzel , Sven Hammerschmidt, Dmitri I. Svergun, Martin Aepfelbacher , Holger Rohde mBio 11, e01612-20 (19 pp) (2020) |
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eIF3 Associates with 80S Ribosomes to Promote Translation Elongation, Mitochondrial Homeostasis, and Muscle Health Yingying Lin, Fajin Li, Linlu Huang, Christine Polte, Haoran Duan, Jianhuo Fang, Li Sun, Xudong Xing, Guiyou Tian, Yabin Cheng, Zoya Ignatova , Xuerui Yang, Dieter A. Wolf Molecular Cell 79, 575-587.e7 (2020) |
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Expanding the scope of orthogonal translation with pyrrolysyl-tRNA synthetases dedicated to aromatic amino acids Hsueh-Wei Tseng, Tobias Baumann, Huan Sun, Yane-Shih Wang, Zoya Ignatova , Nediljko Budisa Molecules 25 (19) 4418 (18 pp) (2020) |
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Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel Ilya A. Osterman, Maximiliane Wieland, Tinashe P. Maviza, Kseniya A. Lashkevich, Dmitrii A. Lukianov, Ekaterina S. Komarova, Yuliya V. Zakalyukina, Robert Buschauer, Dmitrii I. Shiriaev, Semen A. Leyn, Jaime E. Zlamal, Mikhail V. Biryukov, Dmitry A. Skvortsov, Vadim N. Tashlitsky, Vladimir I. Polshakov, Jingdong Cheng, Yury S. Polikanov, Alexey A. Bogdanov, Andrei L. Osterman, Sergey E. Dmitriev, Roland Beckmann, Olga A. Dontsova, Daniel N. Wilson , Petr V. Sergiev Nature Chemical Biology 16, 1071-1077 (2020) |
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Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture Burak Gulen, Marie Rosselin, Joel Fauser, Michael F. Albers, Christian Pett, Christoph Krisp, Vivian Pogenberg, Hartmut Schlüter , Christian Hedberg, Aymelt Itzen Nature Chemistry 12, 732-739 (2020) |
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In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors Karol Nass, Lars Redecke , Markus Perbandt , Oleksandr Yefanov, Marco Klinge, Rudolf Koopmann, Francesco Stellato, Azat G. Gabdoulkhakov, Robert Schönherr, Dirk Rehders , Janine Mia Lahey-Rudolph, Andrew Aquila, Anton Barty, Shibom Basu, R. Bruce Doak, Rainer Duden, Matthias Frank, Raimund Fromme, Stephan Kassemeyer, Gergely Katona, Richard A. Kirian , Haiguang Liu, Irina V. Majoul, Jose Manuel Martin-Garcia, Marc Messerschmidt, Robert L. Shoeman, Uwe Weierstall, Sebastian Westenhoff, Thomas A. White , Garth J. Williams, Chun Hong Yoon, Nadia A. Zatsepin, Petra Fromme, Michael Duszenko, Henry N. Chapman , Christian Betzel Nature Communications 11, 620 (13 pp) (2020) |
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Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion Julia A. Horstmann, Michele Lunelli, Hélène Cazzola, Johannes Heidemann, Caroline Kühne, Pascal Steffen, Sandra Szefs, Claire Rossi, Ravi K. Lokareddy, Chu Wang, Laurine Lemaire, Kelly T. Hughes, Charlotte Uetrecht, Hartmut Schlüter , Guntram A. Grassl, Theresia E. B. Stradal, Yannick Rossez, Michael Kolbe , Marc Erhardt Nature Communications 11, 2013 (11 pp) (2020) |
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Mechanism of ribosome rescue by alternative ribosome-rescue factor B Kai-Hsin Chan, Valentyn Petrychenko, Claudia Müller, Cristina Maracci, Wolf Holtkamp, Daniel N. Wilson , Niels Fischer, Marina V. Rodnina Nature Communications 11, 4106 (11 pp) (2020) |
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Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis Boris Bogdanow, Max Schmidt, Henry Weisbach, Iris Gruska, Barbara Vetter, Koshi Imami, Eleonore Ostermann, Wolfram Brune , Matthias Selbach, Christian Hagemeier, Lüder Wiebusch Nature Communications 11, 4845 (13 pp) (2020) |
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Germline AGO2 mutations impair RNA interference and human neurological development Davor Lessel, Daniela M. Zeitler, Margot R. F. Reijnders, Andriy Kazantsev, Fatemeh Hassani Nia, Alexander Bartholomäus, Victoria Martens, Astrid Bruckmann, Veronika Graus, Allyn McConkie-Rosell, Marie McDonald, Bernarda Lozic, Ee-Shien Tan, Erica Gerkes, Jessika Johannsen, Jonas Denecke, Aida Telegrafi, Evelien Zonneveld-Huijssoon, Henny H. Lemmink, Breana W. M. Cham, Tanja Kovacevic, Linda Ramsdell, Kimberly Foss, Diana Le Duc, Diana Mitter, Steffen Syrbe, Andreas Merkenschlager, Margje Sinnema, Bianca Panis, Joanna Lazier, Matthew Osmond, Taila Hartley, Jeremie Mortreux, Tiffany Busa, Chantal Missirian, Pankaj Prasun, Sabine Lüttgen, Ilaria Mannucci, Ivana Lessel, Claudia Schob, Stefan Kindler, John Pappas, Rachel Rabin, Marjolein Willemsen, Thatjana Gardeitchik, Katharina Löhner, Patrick Rump, Kerith-Rae Dias, Carey-Anne Evans, Peter Ian Andrews, Tony Roscioli, Han G. Brunner, Chieko Chijiwa, M. E. Suzanne Lewis, Rami Abou Jamra, David A. Dyment, Kym M. Boycott, Alexander P. A. Stegmann, Christian Kubisch, Ene-Choo Tan, Ghayda M. Mirzaa, Kirsty McWalter, Tjitske Kleefstra, Rolph Pfundt, Zoya Ignatova , Gunter Meister, Hans-Jürgen Kreienkamp Nature Communications 11, 5797 (14 pp) (2020) |
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Herpesviruses induce aggregation and selective autophagy of host signalling proteins NEMO and RIPK1 as an immune-evasion mechanism Elena Muscolino, Rebekka Schmitz, Stefan Loroch, Enrico Caragliano, Carola Schneider, Matteo Rizzato, Young-Hyun Kim, Eva Krause, Vanda Juranic Lisnic, Albert Sickmann, Rudolph Reimer, Eleonore Ostermann, Wolfram Brune Nature Microbiology 5, 331-342 (2020) |
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The use of sonicated lipid vesicles for mass spectrometry of membrane protein complexes Dror S. Chorev, Haiping Tang, Sarah L. Rouse, Jani Reddy Bolla, Andriko von Kügelgen, Lindsay A. Baker, Di Wu, Joseph Gault, Kay Grünewald , Tanmay A. M. Bharat, Stephen J. Matthews, Carol V. Robinson Nature Protocols 15, 1690-1706 (2020) |
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Target protection as a key antibiotic resistance mechanism Daniel N. Wilson , Vasili Hauryliuk, Gemma C. Atkinson, Alex J. O'Neill Nature Reviews Microbiology 18, 637-648 (2020) |
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The three-dimensional structure of human β-endorphin amyloid fibrils Carolin Seuring , Joeri Verasdonck, Julia Gath, Dhimam Ghosh, Nadezhda Nespovitaya, Marielle Aulikki Walti, Samir K. Maji, Riccardo Cadalbert, Peter Guntert, Beat H. Meier, Roland Riek Nature Structural & Molecular Biology 27, 1178-1184 (2020) |
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Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein Dominik Vogel, Sigurdur R. Thorkelsson, Emmanuelle R. J. Quemin, Kristina Meier, Tomas Kouba, Nadja Gogrefe, Carola Busch, Sophia Reindl, Stephan Günther , Stephen Cusack, Kay Grünewald , Maria Rosenthal Nucleic Acids Research 48, 5749-5765 (2020) |
| 17 |
The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis Heinrich Schäfer, Bertrand Beckert, Christian K. Frese, Wieland Steinchen, Aaron M. Nuss, Michael Beckstette, Ingo Hantke, Kristina Driller, Petra Sudzinová, Libor Krásný, Volkhard Kaever, Petra Dersch, Gert Bange, Daniel N. Wilson , Kürsad Turgay PLoS Genetics 16, e1008275 (34 pp) (2020) |
| 16 |
Murine cytomegaloviruses m139 targets DDX3 to curtail interferon production and promote viral replication Olha Puhach, Eleonore Ostermann, Christoph Krisp, Giada Frascaroli, Hartmut Schlüter , Melanie M. Brinkmann, Wolfram Brune PLoS Pathogens 16, e1008546 (27 pp) (2020) |
| 15 |
Fluorescent protein tagging of adenoviral proteins pV and pIX reveals 'late virion accumulation compartment' Søren Pfitzner, Helga Hofmann-Sieber, Jens B. Bosse, Linda E. Franken, Kay Grünewald , Thomas Dobner PLoS Pathogens 16, e1008588 (25 pp) (2020) |
| 14 |
A molecular pore spans the double membrane of the coronavirus replication organelle Georg Wolff, Ronald W. A. L. Limpens, Jessika C. Zevenhoven-Dobbe, Ulrike Laugks, Shawn Zheng, Anja W. M. de Jong, Roman I. Koning, David A. Agard, Kay Grünewald , Abraham J. Koster, Eric J. Snijder, Montserrat Bárcena Science 369 (6509) 1395-1398 (2020) |
| 13 |
The prefusion structure of Herpes simplex virus glycoprotein B Benjamin Vollmer, Vojtech Pražák, Daven Vasishtan, Elizabeth E. Jefferys, Anna Hernández Durán, Melina Vallbracht, Barbara G. Klupp, Thomas C. Mettenleiter, Marija Backovic, Felix A. Rey, Maya Topf, Kay Grünewald Science Advances 6, eabc1726 (11 pp) (2020) |
| 12 |
High-resolution crystal structure and biochemical characterization of a GH11 endoxylanase from Nectria haematococca Hina Andaleeb, Najeeb Ullah, Sven Falke, Markus Perbandt , Hévila Brognaro, Christian Betzel Scientific Reports 10, 15658 (13 pp) (2020) |
| 11 |
A Technical Introduction to Transmission Electron Microscopy for Soft-Matter: Imaging, Possibilities, Choices, and Technical Developments Linda E. Franken, Kay Grünewald , Egbert J. Boekema, Marc C. A. Stuart Small 16, 1906198 (15 pp) (2020) |
| 10 |
Pulsed electric fields induce modulation of protein liquid-liquid phase separation Mengying Wang, Sven Falke, Robin Schubert, Kristina Lorenzen, Qing-di Cheng, Christian Exner, Hévila Brognaro, Celestin Nzanzu Mudogo, Christian Betzel Soft Matter 16, 8547-8553 (2020) |
| 9 |
Structural Kinetics of MsbA Investigated by Stopped-Flow Time-Resolved Small-Angle X-Ray Scattering Inokentijs Josts, Yunyun Gao, Diana C. F. Monteiro, Stephan Niebling, Julius Nitsche, Katharina Veith, Tobias W. Gräwert, Clement E. Blanchet, Martin A. Schroer, Nils Huse , Arwen R. Pearson , Dmitri I. Svergun, Henning Tidow Structure 28, 348-354.e3 (2020) |
| 8 |
Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles Aisha Manuwar, Benjamin Dreyer, Andreas Böhmert, Anwar Ullah, Zia Mughal, Ahmed Akrem, Syed Abid Ali, Hartmut Schlüter , Christian Betzel Toxins 12, 669 (41 pp) (2020) |
| 7 |
Reply to Comments on Proteomic Investigations of Two Pakistani Naja Snake Venom Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles. Toxins 2020, 12, 669 Aisha Munawar, Benjamin Dreyer, Hartmut Schlüter , Christian Betzel Toxins 12, 781 (3 pp) (2020) |
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Protein phase separation and determinants of in cell crystallization Celestin N. Mudogo, Sven Falke, Hévila Brognaro, Michael Duszenko, Christian Betzel Traffic 21, 220-230 (2020) |
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N-terminal VP1 Truncations Favor T = 1 Norovirus-Like Particles Ronja Pogan, Victor U. Weiss, Kevin Bond, Jasmin Dülfer, Christoph Krisp, Nicholas Lyktey, Jürgen Müller-Guhl, Samuele Zoratto, Günter Allmaier, Martin F. Jarrold, César Muñoz-Fontela, Hartmut Schlüter , Charlotte Uetrecht Vaccines 9, 8 (17 pp) (2020) |
| 4 |
Bacterial
Resistance to Antibiotics Anke Heisig, Peter Heisig -/- Editor: Stefan Offermanns, Walter Rosenthal Encyclopedia of Molecular Pharmacology Online: 01 June 2020 (17 pp) (2020) |
| 3 |
Preparing proteoforms of therapeutic proteins for top-down mass spectrometry Siti Nurul Hidayah , Manasi Gaikwad, Laura Heikaus, Hartmut Schlüter -/- Editor: Xianquan Zhan Proteoforms 27-46 (2020), ISBN 978-1-83880-034-5 |
| 2 |
Animal luring device containing genetically engineered microorganisms producing attractant molecules, an active agent and a microbial nutrient source Daniel Wedemeyer, Henning Jacobsen, Alexander Kartheiser, Nina Patricia Kähler, Nele Burckhardt, Dustin Krüger, Martin Borowski, Alan Wypych, Nadine Fischer, Carla von Salisch, Oda-Emilia Meyfarth, Nico Domschke, Finni Speckenheuer, Bjarne Klopprogge, Roderich R. R. Meißner, Lisa Pütthoff, Nicole Freese, Markus Winkler, Lea Daniels, Dominika Wawrzyniak, Zoya Ignatova , Jonas Hoffmeister -/- Applicants: Universität Hamburg Patent: WO 2020049118 (A1) 2020-03-12 |
| 1 |
Synthetic transfer RNA with extended anticodon loop Zoya Ignatova , Andrew E. Torda -/- Applicants: Universität Hamburg Patent: WO 2020208169 (A1) 2020-10-15 |