Department of Chemestry
Short biography and Publications by Dessi Georgieva
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| Search: Chemistry Dep. / all Hamburg | |
| 2017 | |
| 56 |
Protein profile analysis of two Australian snake venoms by one-dimensional gel electrophoresis and MS/MS experiments Dessislava Nikolova Georgieva, Diana Hildebrand, Rodrigo Simas, Mônika A. Coronado, Marcel Kwiatkowski, Hartmut Schlüter , Raghuvir K. Arni, Patrick J. Spencer, Christian Betzel Current Medicinal Chemistry 24, 1892-1908 (2017) |
2014 | |
| 55 |
Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis Aisha Munawar, Dessislava Nikolova Georgieva, Christian Betzel , Maria Trusch, Henning N. Behnken, Diana Hildebrand, Marcel Kwiatkowski, Sönke Harder, Hartmut Schlüter , Raghuvir K. Arni, Patrick J. Spencer Toxins 6, 850-868 (2014) |
| 54 |
Structure-Function Relationship in Heterodimeric Neurotoxin PLA2s from Viperidae Snakes Inhabiting Europe, South America, and Asia. Functional Importance of the Nontoxic Components Dessislava Nikolova Georgieva, Raghuvir K. Arni, Christian Betzel -/- Editor: P. Gopalakrishnakone, Juan J. Calvete Venom Genomics and Proteomics 16 pp (2014), Publisher: Springer Science+Business Media, Dordrecht |
2013 | |
| 53 |
Structure of the polypeptide crotamine from the Brazilian rattlesnake Crotalus durissus terrificus Mônika A. Coronado, Azat G. Gabdoulkhakov, Dessislava Nikolova Georgieva, Sankaran Banumathi, Mário T. Murakami, Raghuvir K. Arni, Christian Betzel Acta Crystallographica, Section D: Biological Crystallography D69, 1958-1964 (2013) |
2012 | |
| 52 |
Purification, crystallization and preliminary X-ray diffraction analysis of crotamine, a myotoxic polypeptide from the Brazilian snake Crotalus durissus terrificus Mônika A. Coronado, Dessislava Nikolova Georgieva, Friedrich Buck, Azat G. Gabdoulkhakov, Anwar Ullah, Patrick J. Spencer, Raghuvir K. Arni, Christian Betzel Acta Crystallographica, Section F: Structural Biology and Crystallization Communications F68, 1052-1054 (2012) |
| 51 |
Crystal structure of a dimeric Ser49 PLA2-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity Dessislava Nikolova Georgieva, Mônika A. Coronado, Dominik Oberthür , Friedrich Buck, Deyan Duhalov, Raghuvir K. Arni, Christian Betzel Molecular BioSystems 8, 1405-1411 (2012) |
2011 | |
| 50 |
Phospholipase A2 Christian Betzel , Tej P. Singh, Dessislava Nikolova Georgieva, Nicolay Genov Encyclopedia of Inorganic and Bioinorganic Chemistry 1-16 (2011) (This article was originally published in the Handbook of Metalloproteins in 2006) |
| 49 |
Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis Tse Siang Kang, Dessislava Nikolova Georgieva, Nicolay Genov, Mário T. Murakami, Mau Sinha, Ramasamy P. Kumar, Punit Kaur, Sanjit Kumar, Sharmistha Dey, Sujata Sharma, Alice Vrielink, Christian Betzel , Soichi Takeda, Raghuvir K. Arni, Tej P. Singh, R. Manjunatha Kini FEBS Journal 278, 4544-4576 (2011) |
| 48 |
Pseudechis australis Venomics: Adaptation for a Defense against Microbial Pathogens and Recruitment of Body Transferrin Dessislava Nikolova Georgieva, Jana Seifert, Michaela Öhler, Martin von Bergen, Patrick J. Spencer, Raghuvir K. Arni, Nicolay Genov, Christian Betzel Journal of Proteome Research 10, 2440-2464 (2011) |
| 47 |
The structure of a native L-amino acid oxidase, the major component of the Vipera ammodytes ammodytes venomic, reveals dynamic active site and quaternary structure stabilization by divalent ions Dessislava Nikolova Georgieva, Mário T. Murakami, Markus Perbandt , Raghuvir K. Arni, Christian Betzel Molecular BioSystems 7, 379-384 (2011) |
| 46 |
Venom peptide analysis of Vipera ammodytes meridionalis (Viperinae) and Bothrops jararacussu (Crotalinae) demonstrates subfamily-specificity of the peptidome in the family Viperidae Aisha Munawar, Maria Trusch, Dessislava Nikolova Georgieva, Patrick J. Spencer, Violette Frochaux, Sönke Harder, Raghuvir K. Arni, Deyan Duhalov, Nicolay Genov, Hartmut Schlüter , Christian Betzel Molecular BioSystems 7, 3298-3307 (2011) |
| 45 |
Three-Dimensional Modelling of Honeybee Venom Allergenic Proteases: Relation to Allergenicity Dessislava Nikolova Georgieva, Kerstin Greunke, Raghuvir K. Arni, Christian Betzel Zeitschrift für Naturforschung, C: Journal of Biosciences 66c, 305-312 (2011) |
2010 | |
| 44 |
Snake Venomic of Crotalus durissus terrificus- Correlation with Pharmacological Activities Dessislava Nikolova Georgieva, Michaela Öhler, Jana Seifert, Martin von Bergen, Raghuvir K. Arni, Nicolay Genov, Christian Betzel Journal of Proteome Research 9, 2302-2316 (2010) |
| 43 |
The Venomics of Bothrops alternatus is a Pool of Acidic Proteins with Predominant Hemorrhagic and Coagulopathic Activities Michaela Öhler, Dessislava Nikolova Georgieva, Jana Seifert, Martin von Bergen, Raghuvir K. Arni, Nicolay Genov, Christian Betzel Journal of Proteome Research 9, 2422-2437 (2010) |
| 42 |
Three-dimensional model of the honeybee venom allergen Api m 7: Structural and functional insights Dessislava Nikolova Georgieva, Kerstin Greunke, Christian Betzel Molecular BioSystems 6, 1056-1060 (2010) |
| 41 |
Interactions of ginkgolides A and B with a recombinant human prion protein Dessislava Nikolova Georgieva, Lars Redecke , Martin von Bergen, Nicolay Genov, Christian Betzel Protein & Peptide Letters 17, 399-404 (2010) |
| 40 |
Venom on ice: First insights into Antarctic octopus venoms E. A. B. Undheim, Dessislava Nikolova Georgieva, H. H. Thoen, J. A. Norman, J. Mork, Christian Betzel , B. G. Fry Toxicon 56, 897-913 (2010) |
2009 | |
| 39 |
3-D Model of the bee venom acid phosphatase: Insights into allergenicity Dessislava Nikolova Georgieva, Kerstin Greunke, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 378, 711-715 (2009) |
| 38 |
Snake venomics of the Siamese Russell's viper (Daboia russelli siamensis) - Relation to pharmacological activities Michaela Risch, Dessislava Nikolova Georgieva, Martin von Bergen, Nico Jehmlich, Nicolay Genov, Raghuvir K. Arni, Christian Betzel Journal of Proteomics 72, 256-269 (2009) |
2008 | |
| 37 |
Isolation, crystallization and preliminary X-ray diffraction analysis of L-amino-acid oxidase from Vipera ammodytes ammodytes venom Dessislava Nikolova Georgieva, Anna Kardas, Friedrich Buck, Markus Perbandt , Christian Betzel Acta Crystallographica, Section F: Structural Biology and Crystallization Communications F64, 918-921 (2008) |
| 36 |
Proteome analysis of snake venom toxins: pharmacological insights Dessislava Nikolova Georgieva, Raghuvir K. Arni, Christian Betzel Expert Review of Proteomics 5, 787-797 (2008) |
| 35 |
Comparative Analysis of the Venom Proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis Dessislava Nikolova Georgieva, Michaela Risch, Anna Kardas, Friedrich Buck, Martin von Bergen, Christian Betzel Journal of Proteome Research 7, 866-886 (2008) |
2007 | |
| 34 |
Structural characterization of β-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro Lars Redecke , Martin von Bergen, Joachim Clos, Petr V. Konarev, Dmitri I. Svergun, Ursula E. A. Fittschen , José A. C. Broekaert, Oliver T. Bruns, Dessislava Nikolova Georgieva, Eckhard Mandelkow, Nicolay Genov, Christian Betzel Journal of Structural Biology 157, 308-320 (2007) |
2006 | |
| 33 |
Interactions of recombinant prions with compounds of therapeutical significance Dessislava Nikolova Georgieva, Daniel Schwark, Martin von Bergen, Lars Redecke , Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 344, 463-470 (2006) |
| 32 |
Phl p 3: structural and immunological characterization of a major allergen of timothy grass pollen Arnd Petersen, Roland Suck, Buko Lindner, Dessislava Nikolova Georgieva, Martin Ernst, Holger Notbohm, Daniel Wicklein, Oliver Cromwell, Wolf-Meinhard Becker Clinical and Experimental Allergy 36, 840-849 (2006) |
| 31 |
Phospholipase A2 as a biomarker of pathophysiological processes Christian Betzel , Dessislava Nikolova Georgieva, Mário T. Murakami, Raghuvir K. Arni, Nicolay Genov Current Topics in Biochemical Research 8, 87-93 (2006) |
| 30 |
Catalytic efficiencies of alkaline proteinases from microorganisms Dessislava Nikolova Georgieva, Nicolay Genov, Wolfgang Voelter, Christian Betzel Zeitschrift für Naturforschung, C: Journal of Biosciences 61c, 445-452 (2006) |
2005 | |
| 29 |
Conformational
states of the Rapana thomasiana hemocyanin and its substructures studied by dynamic light scattering and time-resolved fluorescence spectroscopy Dessislava Nikolova Georgieva, Daniel Schwark, Peter Nikolov, Krassimira Idakieva, Katja Parvanova, Karsten Dierks, Nicolay Genov, Christian Betzel Biophysical Journal 88, 1276-1282 (2005) |
| 28 |
Bacillus licheniformis Variant DY Proteinase: Specificity in Relation to the Geometry of the Substrate Recognition Site Dessislava Nikolova Georgieva, Nicolay Genov, Christian Betzel Current Microbiology 51, 71-74 (2005) |
| 27 |
Comparative Analysis of the Human and Chicken Prion Protein Copper Binding Regions at pH 6.5 Lars Redecke , Wolfram Meyer-Klaucke, Mirjam Koker, Joachim Clos, Dessislava Nikolova Georgieva, Nicolay Genov, Hartmut Echner, Hubert Kalbacher, Markus Perbandt , Reinhard Bredehorst, Wolfgang Voelter, Christian Betzel Journal of Biological Chemistry 280, 13987-13992 (2005) |
2004 | |
| 26 |
The X-ray structure of a snake venom Gln48 phospholipase A2 at 1.9 Å resolution reveals anion-binding sites Dessislava Nikolova Georgieva, Markus Perbandt , Wojciech Rypniewski, Krassimir Hristov, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 316, 33-38 (2004) |
| 25 |
Asp49 phospholipase A2-elaidoylamide complex: a new mode of inhibition Dessislava Nikolova Georgieva, Wojciech Rypniewski, Azat G. Gabdoulkhakov, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 319, 1314-1321 (2004) |
| 24 |
Oligomerization of the proteolytic products is an intrinsic property of prion proteins Dessislava Nikolova Georgieva, Mirjam Koker, Lars Redecke , Markus Perbandt , Joachim Clos, Reinhard Bredehorst, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 323, 1278-1286 (2004) |
| 23 |
Synthetic human prion protein octapeptide repeat binds to the proteinase K active site Dessislava Nikolova Georgieva, Wojciech Rypniewski, Hartmut Echner, Markus Perbandt , Mirjam Koker, Joachim Clos, Lars Redecke , Reinhard Bredehorst, Wolfgang Voelter, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 325, 1406-1411 (2004) |
| 22 |
Interactions of the neurotoxin vipoxin in solution studied by dynamic light scattering Dessislava Nikolova Georgieva, Nicolay Genov, Krassimir Hristov, Karsten Dierks, Christian Betzel Biophysical Journal 86, 461-466 (2004) |
| 21 |
Contribution of disulfide bonds and calcium to molluscan hemocyanin stability Dessislava Nikolova Georgieva, Nicolay Genov, Markus Perbandt , Wolfgang Voelter, Christian Betzel Zeitschrift für Naturforschung, C: Journal of Biosciences 59c, 281-287 (2004) |
| 20 |
Phospholipase A2 Christian Betzel , Tej P. Singh, Dessislava Nikolova Georgieva, Nicolay Genov Handbook of Metalloproteins 3, 677-691 (2004) |
2003 | |
| 19 |
Structure of the heterodimeric neurotoxic complex viperotoxin F (RV-4/RV-7) from the venom of Vipera russelli formosensis at 1.9 Å resolution Markus Perbandt , Inn-Ho Tsai, Annemarie Fuchs, Sankaran Banumathi, Kanagalaghatta R. Rajashankar, Dessislava Nikolova Georgieva, Narayana Kalkura, Tej P. Singh, Nicolay Genov, Christian Betzel Acta Crystallographica, Section D: Biological Crystallography D59, 1679-1687 (2003) |
| 18 |
Crystallization and preliminary x-ray diffraction studies of a toxic phospholipase A2 from the venom of Vipera ammodytes meridionalis complexed to a synthetic inhibitor Dessislava Nikolova Georgieva, Wojciech Rypniewski, Markus Perbandt , Mahendra Jain, Nicolay Genov, Christian Betzel Biochimica et Biophysica Acta, Proteins and Proteomics 1650, 1-3 (2003) |
| 17 |
Structure-function relationships in the neurotoxin Vipoxin from the venom of Vipera ammodytes meridionalis Dessislava Nikolova Georgieva, Nicolay Genov, Peter Nikolov, Boris Aleksiev, Kanagalaghatta R. Rajashankar, Wolfgang Voelter, Christian Betzel Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 59A, 617-627 (2003) |
2002 | |
| 16 |
The major extracellular protease of the nosocomial pathogen Stenotrophomonas maltophilia. Characterization of the protein and molecular cloning of the gene Sabine Windhorst, Eva Frank, Dessislava Nikolova Georgieva, Nicolay Genov, Fritz Buck, Peter Borowski, Wolfgang Weber Journal of Biological Chemistry 277, 11042-11049 (2002) |
2001 | |
| 15 |
Differences in the specificities of the highly alkalophilic proteinases Savinase and Esperase imposed by changes in the rigidity and geometry of the substrate binding sites Dessislava Nikolova Georgieva, Stanka Stoeva, Wolfgang Voelter, Nicolay Genov, Christian Betzel Archives of Biochemistry and Biophysics 387, 197-201 (2001) |
| 14 |
Substrate specificity of the highly alkalophilic bacterial proteinase Esperase: Relation to the x-ray structure Dessislava Nikolova Georgieva, Stanka Stoeva, Wolfgang Voelter, Nicolay Genov, Christian Betzel Current Microbiology 42, 368-371 (2001) |
| 13 |
Penaeus monodon (tiger shrimp) hemocyanin: subunit composition and thermostability Stanka Stoeva, Krassimira Idakieva, Dessislava Nikolova Georgieva, Wolfgang Voelter, Nicolay Genov Zeitschrift für Naturforschung, C: Journal of Biosciences 56, 416-422 (2001) |
| 12 |
Viviparus ater hemocyanin: investigation of the dioxygen-binding site and stability of the oxy- and apo-forms Dessislava Nikolova Georgieva, Stanka Stoeva, Wolfgang Voelter, Nicolay Genov Zeitschrift für Naturforschung, C: Journal of Biosciences 56, 843-847 (2001) |
2000 | |
| 11 |
Taxonomy of Thermoactinomyces sacchari, subsp. Nov. No 5, producer of neutral proteinase. I. Phenotypical characteristics Adriana Gusterova, D. Spassova, Dessislava Nikolova Georgieva, R. Tzvetkova, Veneta Ivanova Comptes Rendus de l'Academie Bulgare des Sciences 53, 83-86 (2000) |
| 10 |
Specificity of a neutral Zn-dependent proteinase from Thermoactinomyces sacchari toward the oxidized insulin B chain Dessislava Nikolova Georgieva, Stanka Stoeva, Veneta Ivanova, Adriana Gusterova, Wolfgang Voelter Current Microbiology 41, 70-72 (2000) |
| 9 |
Spectroscopic investigation of calcium binding sites in the neurotoxin Vipoxin and its components-relation with the X-ray structure Dessislava Nikolova Georgieva, Christian Betzel , Boris Aleksiev, Nicolay Genov Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 56A, 2811-2816 (2000) |
1999 | |
| 8 |
Oxygen transport proteins: II. Chemical and spectroscopic properties of scorpion (Buthus sindicus) native hemocyanin and purified subunit Bsin1 Syed Abid Ali, Stanka Stoeva, Atiya Abbasi, Dessislava Nikolova Georgieva, Nicolay Genov, Wolfgang Voelter Comparative Biochemistry and Physiology, Part A: Molecular & Integrative Physiology 122A, 65-74 (1999) |
| 7 |
Spectroscopic investigation of phenolic groups ionization in the vipoxin neurotoxic phospholipase A2: comparison with the X-ray structure in the region of the tyrosyl residues Dessislava Nikolova Georgieva, Nicolay Genov, Kanagalaghatta R. Rajashankar, Boris Aleksiev, Christian Betzel Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 55A, 239-244 (1999) |
| 6 |
Fluorescence properties of Savinase: the x-ray structure in the region of the tryptophyl residues Dessislava Nikolova Georgieva, Peter Nikolov, Veneta Ivanova, Adriana Gusterova, Christian Betzel Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 55A, 2309-2319 (1999) |
1998 | |
| 5 |
A novel thermostable neutral proteinase from Saccharomonospora canescens Pavlina Dolashka, Dessislava Nikolova Georgieva, Stanka Stoeva, Nicolay Genov, Rossen Rachev, Adriana Gusterova, Wolfgang Voelter Biochimica et Biophysica Acta, Protein Structure and Molecular Enzymology 1382, 207-216 (1998) |
| 4 |
Circular dichroism study of the hemocyanin thermostability Dessislava Nikolova Georgieva, Stanka Stoeva, Syed Abid Ali, Atiya Abbasi, Nicolay Genov, Wolfgang Voelter Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 54A, 765-771 (1998) |
| 3 |
Steady-state and time-resolved fluorescence of Esperase: comparison with the x-ray structure in the region of the two tryptophans Dessislava Nikolova Georgieva, Peter Nikolov, Christian Betzel Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 54A, 1109-1116 (1998) |
1997 | |
| 2 |
A novel thermostable inhibitor of trypsin and subtilisin from the seeds of Brassica nigra: amino acid sequence, inhibitory and spectroscopic properties and thermostability Nicolay Genov, Ivan Goshev, Diana Nikolova, Dessislava Nikolova Georgieva, Bruno Filippi, Ib Svendsen Biochimica et Biophysica Acta, Protein Structure and Molecular Enzymology 1341, 157-164 (1997) |
| 1 |
Spectroscopic properties of subtilisin DY selectively modified with fluorescein isothiocyanate Dessislava Nikolova Georgieva, Pavlina Dolashka Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 53A, 1515-1520 (1997) |