Fachbereich Chemie
Publikationen von Zoya Ignatova
.
| Suche: FB Chemie / Hamburg | |
| 2024 | |
| 142 |
Automated high-throughput selection of DNA aptamers using a common optical next-generation sequencer Alissa Drees , Christian Ahlers, Timothy Kehrer, Natascha Ehmke, Alice Frederike Rosa Grün, Charlotte Uetrecht, Zoya Ignatova , Udo Schumacher, Markus Fischer bioRxiv 2024.06.24.600375, 43 pp (2024) |
| 141 |
N6-methyladenosine in 5'-UTR does not promote translation initiation Ewelina Guca, Rodrigo Alarcon, Michael Z. Palo, Leonardo Santos, Santiago Alonso-Gil, Marcos Davyt, Leonardo H. F. de Lima, Fanny Boissier, Sarada Das, Bojan Zagrovic, Joseph D. Puglisi, Yaser Hashem , Zoya Ignatova Molecular Cell 84, 584-595 (2024) |
| 140 |
Translation velocity determines the efficacy of engineered suppressor tRNAs on pathogenic nonsense mutations Nikhil Bharti, Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jimenez-Sanchez, Jeong S. Hong, Andras Rab, Eric J. Sorscher, Suki Albers , Zoya Ignatova Nature Communications 15, 2957 (2024) |
| 139 |
tRNA therapeutics for genetic diseases Jeff Coller, Zoya Ignatova Nature Reviews Drug Discovery 23, 108-125 (2024) |
| 138 |
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa Jonas Krueger, Matthias Preusse, Nicolas Oswaldo Gomez, Yannick Noah Frommeyer, Sebastian Doberenz, Anne Lorenz, Adrian Kordes, Svenja Grobe, Mathias Müsken, Daniel P. Depledge, Sarah L. Svensson, Siegfried Weiss, Volkhard Kaever, Andreas Pich, Cynthia M. Sharma, Zoya Ignatova , Susanne Häussler Proceedings of the National Academy of Sciences of the United States of America 121, e2312874121 (12 pp) (2024) |
| 137 |
Synthetic DNA construct encoding suppressor tRNA Zoya Ignatova , Suki Albers-Fomenko , Marcos Davyt, Nikhil Bharti -/- Anmelder: Universität Hamburg Patent: WO 2024208970 (A2) 2024-10-10; EP 4442826 (A1) 2024-10-09 |
| 136 |
Pharmaceutical composition comprising multiple suppressor transfer RNAs Zoya Ignatova , Nikhil Bharti, Marcos Davyt -/- Anmelder: Universität Hamburg Patent: WO 2024227728 (A1) 2024-11-07; EP 4458967 (A1) 2024-11-06 |
2023 | |
| 135 |
Tailored Synthetic sRNAs Dynamically Tune Multilayer Genetic Circuits Ana K. Velazquez Sanchez, Bjarne Klopprogge, Karl-Heinz Zimmermann, Zoya Ignatova ACS Synthetic Biology 12, 2524-2535 (2023) |
| 134 |
Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events George Allen, Benjamin Weiss, Olesya O. Panasenko, Susanne Huch, Zoltan Villanyi, Benjamin Albert, Daniel Dilg, Marina Zagatti, Paul Schaughency, Susan E. Liao, Jeff Corden, Christine Polte, David Shore, Zoya Ignatova , Vicent Pelechano, Martine A. Collart Genome Biology 24, 30 (27 pp) (2023) |
| 133 |
Effect
of mRNA/tRNA mutations on translation speed: Implications for human diseases Marcos Davyt, Nikhil Bharti, Zoya Ignatova Journal of Biological Chemistry 299, 105089 (16 pp) (2023) |
| 132 |
Engineered tRNAs suppress nonsense mutations in cells and in vivo Suki Albers , Elizabeth C. Allen, Nikhil Bharti, Marcos Davyt, Disha Joshi, Carlos G. Perez-Garcia, Leonardo Santos, Rajesh Mukthavaram, Miguel Angel Delgado-Toscano, Brandon Molina, Kristen Kuakini, Maher Alayyoubi, Kyoung-Joo Jenny Park, Grishma Acharya, Jose A. Gonzalez, Amit Sagi, Susan E. Birket, Guillermo J. Tearney, Steven M. Rowe, Candela Manfredi, Jeong S. Hong, Kiyoshi Tachikawa, Priya Karmali, Daiki Matsuda, Eric J. Sorscher, Pad Chivukula, Zoya Ignatova Nature 618, 842-848 (2023) |
| 131 |
Synthetic Transfer RNA with Modified Nucleotides Zoya Ignatova , Suki Albers -/- Anmelder: Universität Hamburg Patent: WO 2023118456 (A1) 2023-06-29; EP 4202045 (A1) 2023-06-28 |
2022 | |
| 130 |
Improving the Robustness of Engineered Bacteria to Nutrient Stress Using Programmed Proteolysis Klara Szydlo, Zoya Ignatova , Thomas E. Gorochowski ACS Synthetic Biology 11, 1049-1059 (2022) |
| 129 |
Immunoprecipation assay to quantify the amount of tRNAs associated with their interacting proteins in tissue and cell culture Sarada Das, Amila Zuko, Robin Thompson, Erik Storkebaum, Zoya Ignatova Bio-Protocol 12, e4335 (2022) |
| 128 |
Survival Advantage of Lymphadenectomy in Patients with Ovarian Cancer Atanas Ignatov, Sheref Salim Hassan, Stylianos Ivros, Thomas Papathemelis, Zoya Ignatova , Holm Eggemann Cancer Investigation 40, 621-628 (2022) |
| 127 |
Solution Structure and Conformational Flexibility of a Polyketide Synthase Module Maja Klaus, Emanuele Rossini, Andreas Linden, Karthik S. Paithankar, Matthias Zeug, Zoya Ignatova , Henning Urlaub, Chaitan Khosla, Jürgen Köfinger, Gerhard Hummer, Martin Grininger JACS Au 1, 2162-2171 (2022) |
| 126 |
Structure of Escherichia coli heat shock protein Hsp15 in complex with the ribosomal 50S subunit bearing peptidyl-tRNA Haaris A. Safdari, Sergo Kasvandik, Christine Polte, Zoya Ignatova , Tanel Tenson, Daniel N. Wilson Nucleic Acids Research 50, 12515-12526 (2022) |
| 125 |
mRNAs sequestered in stress granules recover nearly completely for translation Sarada Das, Leonardo Santos, Antonio Virgilio Failla, Zoya Ignatova RNA Biology 19, 877-884 (2022) |
2021 | |
| 124 |
Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A George E. Allen, Olesya O. Panasenko, Zoltan Villanyi, Marina Zagatti, Benjamin Weiss, Lucile Pagliazzo, Susanne Huch, Christine Polte, Szabolcs Zahoran, Christopher S. Hughes, Vicent Pelechano, Zoya Ignatova , Martine A. Collart Cell Reports 36, 109633 (2021) |
| 123 |
The Effect of Synonymous Single-Nucleotide Polymorphisms on an Atypical Cystic Fibrosis Clinical Presentation Giovana B. Bampi, Anabela S. Ramalho, Leonardo A. Santos, Johannes Wagner, Lieven Dupont, Harry Cuppens, Kris de Boeck, Zoya Ignatova Life 11, 14 (9 pp) (2021) |
| 122 |
Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP Caillan Crowe-McAuliffe, Hiraku Takada, Victoriia Murina, Christine Polte, Sergo Kasvandik, Tanel Tenson, Zoya Ignatova , Gemma C. Atkinson, Daniel N. Wilson , Vasili Hauryliuk Molecular Cell 81, 115-126.e7 (2021) |
| 121 |
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens Caillan Crowe-McAuliffe, Victoriia Murina, Kathryn J. Turnbull , Marje Kasari, Merianne Mohamad, Christine Polte, Hiraku Takada, Karolis Vaitkevicius, Jörgen Johansson, Zoya Ignatova , Gemma C. Atkinson, Alex J. O'Neill, Vasili Hauryliuk, Daniel N. Wilson Nature Communications 12, 3577 (14 pp) (2021) |
| 120 |
Repurposing tRNAs for nonsense suppression Suki Albers , Bertrand Beckert, Marco C. Matthies, Chandra Sekhar Mandava, Raphael Schuster, Carolin Seuring , Maria Riedner , Suparna Sanyal, Andrew E. Torda , Daniel N. Wilson , Zoya Ignatova Nature Communications 12, 3850 (10 pp) (2021) |
| 119 |
Estimation of peptide elongation times from ribosome profiling spectra Michael Y. Pavlov, Gustaf Ullman, Zoya Ignatova , Måns Ehrenberg Nucleic Acids Research 49, 5124-5142 (2021) |
| 118 |
RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system Hiraku Takada, Caillan Crowe-McAuliffe, Christine Polte, Zhanna Yu Sidorova, Victoriia Murina, Gemma C. Atkinson, Andrey L. Konevega, Zoya Ignatova , Daniel N. Wilson , Vasili Hauryliuk Nucleic Acids Research 49, 8355-8369 (2021) |
| 117 |
Constraints on error rate revealed by computational study of G|U tautomerization in translation Andriy Kazantsev, Zoya Ignatova Nucleic Acids Research 49, 11823-11833 (2021) |
| 116 |
smORFer: a modular algorithm to detect small ORFs in prokaryotes Alexander Bartholomäus, Baban Kolte, Ayten Mustafayeva, Ingrid Goebel, Stephan Fuchs, Dirk Benndorf, Susanne Engelmann, Zoya Ignatova Nucleic Acids Research 49, e89 (12 pp) (2021) |
| 115 |
Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach Stephan Fuchs, Martin Kucklick, Erik Lehmann, Alexander Beckmann, Maya Wilkens, Baban Kolte, Ayten Mustafayeva, Tobias Ludwig, Maurice Diwo, Josef Wissing, Lothar Jänsch, Christian H. Ahrens, Zoya Ignatova , Susanne Engelmann PLoS Genetics 17, e1009585 (2021) |
| 114 |
Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity Robert Rauscher, Giovana B. Bampi, Marta Guevara-Ferrer, Leonardo A. Santos, Disha Joshi, David Mark, Lisa J. Strug, Johanna M. Rommens, Manfred Ballmann, Eric J. Sorscher, Kathryn E. Oliver, Zoya Ignatova Proceedings of the National Academy of Sciences of the United States of America 118, e2010612118 (2021) |
| 113 |
tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase Amila Zuko, Moushami Mallik, Robin Thompason, Emily L. Spaulding, Anne R. Wienand, Marlje Been, Abigail L. D. Tadenev, Nick van Bakel, Celine Sijlmans, Leonardo A. Santos, Julia Bussmann, Marica Catinozzi, Sarada Das, Divita Julshrestha, Robert W. Burgess, Zoya Ignatova , Erik Storkebaum Science 373, 1161-1166 (2021) |
| 112 |
Characterizing Genetic Parts and Devices Using RNA Sequencing Deepti Vipin, Zoya Ignatova , Thomas E. Gorochowski Methods in Molecular Biology 2229 (Synthetic Gene Circuits) 175-187 (2021) |
| 111 |
Codon Resolution Analysis of Ribosome Profiling Data Alexander Bartholomäus, Zoya Ignatova -/- Herausgeber: Vyacheslav M. Labunskyy Methods in Molecular Biology 2252 (Ribosome Profiling) 251-268 (2021) |
2020 | |
| 110 |
Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells Tamara Fernández-Calero, Marcos Davyt, Karen Perelmuter, Cora Chalar, Giovana Bampi, Helena Persson, Juan Pablo Tosar, Völundur Hafstað, Hugo Naya, Carlos Rovira, Mariela Bollati-Fogolín, Ricardo Ehrlich, Gilles Flouriot, Zoya Ignatova , Mónica Marín Cancer & Metabolism 8, 8 (20 pp) (2020) |
| 109 |
tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation Irem Avcilar-Kucukgoze, Howard Gamper, Christine Polte, Zoya Ignatova , Ralph Krätzner, Michael Shtutman, Ya-Ming Hou, Dawei W. Dong, Anna Kashina Cell Chemical Biology 27, 839-849.e4 (2020) |
| 108 |
Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria Kyle Mangano, Tanja Florin, Xinhao Shao, Dorota Klepacki, Irina Chelysheva, Zoya Ignatova , Yu Gao, Alexander S. Mankin, Nora Vázquez-Laslop eLife 9, e62655 (2020) |
| 107 |
A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2 Meliha Karsak, Konstantin Glebov, Marina Scheffold, Thomas Bajaj, Amit Kawalia, Ilker Karaca, Sebastian Rading, Johannes Kornhuber, Oliver Peters, Monica Diez-Fairen, Lutz Frölich, Michael Hüll, Jens Wiltfang, Martin Scherer, Steffi Riedel-Heller, Anja Schneider, Michael T. Heneka, Klaus Fliessbach, Ahmed Sharaf, Holger Thiele, Martina Lennarz, Frank Jessen, Wolfgang Maier, Christian Kubisch, Zoya Ignatova , Peter Nürnberg, Pau Pastor, Jochen Walter, Alfredo Ramirez Human Mutation 41, 169-181 (2020) |
| 106 |
Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues Giovana B. Bampi, Robert Rauschera, Sebastian Kirchner, Kathryn E. Oliver, Marcel J. C. Bijvelds, Leonardo A. Santos, Johannes Wagner, Raymond A. Frizzell, Hugo R. de Jonge, Eric J. Sorscher, Zoya Ignatova Journal of Cystic Fibrosis 19, 1021-1026 (2020) |
| 105 |
eIF3 Associates with 80S Ribosomes to Promote Translation Elongation, Mitochondrial Homeostasis, and Muscle Health Yingying Lin, Fajin Li, Linlu Huang, Christine Polte, Haoran Duan, Jianhuo Fang, Li Sun, Xudong Xing, Guiyou Tian, Yabin Cheng, Zoya Ignatova , Xuerui Yang, Dieter A. Wolf Molecular Cell 79, 575-587.e7 (2020) |
| 104 |
Expanding the scope of orthogonal translation with pyrrolysyl-tRNA synthetases dedicated to aromatic amino acids Hsueh-Wei Tseng, Tobias Baumann, Huan Sun, Yane-Shih Wang, Zoya Ignatova , Nediljko Budisa Molecules 25 (19) 4418 (18 pp) (2020) |
| 103 |
Germline AGO2 mutations impair RNA interference and human neurological development Davor Lessel, Daniela M. Zeitler, Margot R. F. Reijnders, Andriy Kazantsev, Fatemeh Hassani Nia, Alexander Bartholomäus, Victoria Martens, Astrid Bruckmann, Veronika Graus, Allyn McConkie-Rosell, Marie McDonald, Bernarda Lozic, Ee-Shien Tan, Erica Gerkes, Jessika Johannsen, Jonas Denecke, Aida Telegrafi, Evelien Zonneveld-Huijssoon, Henny H. Lemmink, Breana W. M. Cham, Tanja Kovacevic, Linda Ramsdell, Kimberly Foss, Diana Le Duc, Diana Mitter, Steffen Syrbe, Andreas Merkenschlager, Margje Sinnema, Bianca Panis, Joanna Lazier, Matthew Osmond, Taila Hartley, Jeremie Mortreux, Tiffany Busa, Chantal Missirian, Pankaj Prasun, Sabine Lüttgen, Ilaria Mannucci, Ivana Lessel, Claudia Schob, Stefan Kindler, John Pappas, Rachel Rabin, Marjolein Willemsen, Thatjana Gardeitchik, Katharina Löhner, Patrick Rump, Kerith-Rae Dias, Carey-Anne Evans, Peter Ian Andrews, Tony Roscioli, Han G. Brunner, Chieko Chijiwa, M. E. Suzanne Lewis, Rami Abou Jamra, David A. Dyment, Kym M. Boycott, Alexander P. A. Stegmann, Christian Kubisch, Ene-Choo Tan, Ghayda M. Mirzaa, Kirsty McWalter, Tjitske Kleefstra, Rolph Pfundt, Zoya Ignatova , Gunter Meister, Hans-Jürgen Kreienkamp Nature Communications 11, 5797 (14 pp) (2020) |
| 102 |
Animal luring device containing genetically engineered microorganisms producing attractant molecules, an active agent and a microbial nutrient source Daniel Wedemeyer, Henning Jacobsen, Alexander Kartheiser, Nina Patricia Kähler, Nele Burckhardt, Dustin Krüger, Martin Borowski, Alan Wypych, Nadine Fischer, Carla von Salisch, Oda-Emilia Meyfarth, Nico Domschke, Finni Speckenheuer, Bjarne Klopprogge, Roderich R. R. Meißner, Lisa Pütthoff, Nicole Freese, Markus Winkler, Lea Daniels, Dominika Wawrzyniak, Zoya Ignatova , Jonas Hoffmeister -/- Anmelder: Universität Hamburg Patent: WO 2020049118 (A1) 2020-03-12 |
| 101 |
Synthetic transfer RNA with extended anticodon loop Zoya Ignatova , Andrew E. Torda -/- Anmelder: Universität Hamburg Patent: WO 2020208169 (A1) 2020-10-15 |
2019 | |
| 100 |
Assessing cell-specific effects of genetic variations using tRNA microarrays Christine Polte, Daniel Wedemeyer, Kathryn E. Oliver, Johannes Wagner, Marcel J. C. Bijvelds, John Mahoney, Hugo R. de Jonge, Eric J. Sorscher, Zoya Ignatova BMC Genomics 20 (Supplement 8) 549 (12 pp) (2019) Alternativer Quellentitel: Proceedings of VarI-COSI 2018: identification and annotation of genetic variants in the context of structure, function, and disease: genomics |
| 99 |
A Novel Caenorhabditis Elegans Proteinopathy Model Shows Changes in mRNA Translational Frameshifting During Aging Frauke Adamla, Jarod Rollins, Matthew Newsom, Santina Snow, Markus Schosserer, Clemens Heissenberger, Jordan Horrocks, Aric N. Rogers, Zoya Ignatova Cellular Physiology and Biochemistry 52, 970-983 (2019) |
| 98 |
Computational Aminoacyl-tRNA Synthetase Library Design for Photocaged Tyrosine Tobias Baumann, Matthias Hauf, Florian Richter, Suki Albers , Andreas Möglich, Zoya Ignatova , Nediljko Budisa International Journal of Molecular Sciences 20, 2343 (21 pp) (2019) |
| 97 |
Slowing ribosome velocity restores folding and function of mutant CFTR Kathryn E. Oliver, Robert Rauscher, Marjolein Mijnders, Wei Wang, Matthew J. Wolpert, Jessica Maya, Carleen M. Sabusap, Robert A. Kesterson, Kevin L. Kirk, Andras Rab, Ineke Braakman, Jeong S. Hong, John L. Hartman IV, Zoya Ignatova , Eric J. Sorscher Journal of Clinical Investigation 129, 5236-5253 (2019) |
| 96 |
Absolute quantification of translational regulation and burden using combined sequencing approaches Thomas E. Gorochowski , Irina Chelysheva, Mette Eriksen, Priyanka Nair, Steen Pedersen, Zoya Ignatova Molecular Systems Biology 15, e8719 (15 pp) (2019) Reprint: bioRxiv 338939 (2019) |
| 95 |
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression Feven Tameire, Ioannis I. Verginadis, Nektaria Maria Leli, Christine Polte, Crystal S. Conn, Rani Ojha, Carlo Salas Salinas, Frank Chinga, Alexandra. M. Monroy, Weixuan Fu, Paul Wang, Andrew Kossenkov, Jiangbin Ye, Ravi K. Amaravadi, Zoya Ignatova , Serge Y. Fuchs, J. Alan Diehl, Davide Ruggero, Constantinos Koumenis Nature Cell Biology 21, 889-899 (2019) Erratum: Nature Cell Biology 21, 1052-1052 (2019) |
| 94 |
Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging Susan Amirbeigiarab, Parnian Kiani, Ana Velazquez, Christoph Krisp, Andriy Kazantsev, Lars Fester, Hartmut Schlüter , Zoya Ignatova Proceedings of the National Academy of Sciences of the United States of America 116, 22567-22572 (2019) Erratum: Proceedings of the National Academy of Sciences of the United States of America 116, 24907-24907 (2019) |
| 93 |
Polymerase III transcription is necessary for T cell priming by dendritic cells Marisa Reverendo, Rafael J. Arguello, Christine Polte, Jan Valecka, Voahirana Camosseto, Nathalie Auphan-Anezin, Zoya Ignatova , Evelina Gatti, Philippe Pierre Proceedings of the National Academy of Sciences of the United States of America 116, 22721-22729 (2019) |
| 92 |
Octa-repeat domain of the mammalian prion protein mRNA forms stable A-helical hairpin structure rather than G-quadruplexes Andreas Czech , Petr V. Konarev, Ingrid Goebel, Dmitri I. Svergun, Peter R. Wills, Zoya Ignatova Scientific Reports 9, 2465 (10 pp) (2019) Erratum: Scientific Reports 10, 4378 (2020) |
| 91 |
CD98hc
(SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression Sara Cano-Crespo, Josep Chillarón, Alexandra Junza, Gonzalo Fernández-Miranda, Judit García, Christine Polte, Laura R. de la Ballina, Zoya Ignatova , Óscar Yanes, Antonio Zorzano, Camille Stephan-Otto Attolini, Manuel Palacín Scientific Reports 9, 14065 (19 pp) (2019) |
| 90 |
Synthetic transfer RNA with extended anticodon loop Zoya Ignatova , Andrew E. Torda , Marco Matthies -/- Anmelder: Universität Hamburg Patent: WO 2019175316 (A1) 2019-09-19 |
2018 | |
| 89 |
Timing during translation matters: synonymous mutations in human pathologies influence protein folding and function Robert Rauscher, Zoya Ignatova Biochemical Society Transactions 46, 937-944 (2018) |
| 88 |
The RNA-binding protein Hfq is important for ribosome biogenesis and affects translation fidelity José M. Andrade, Ricardo F. dos Santos, Irina Chelysheva, Zoya Ignatova , Cecilia M. Arraiano EMBO Journal 37, e97631 (2018) |
| 87 |
Dynamic m6A methylation facilitates mRNA triaging to stress granules Maximilian Anders, Irina Chelysheva, Ingrid Goebel, Timo Trenkner, Jun Zhou, Yuanhui Mao, Silvia Verzini, Shu-Bing Qian, Zoya Ignatova Life Science Alliance 1 (4) 113 (2018) Reprint: bioRxiv, Molecular Biology 357012 (2018) |
| 86 |
Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 Bertrand Beckert, Martin Turk, Andreas Czech , Otto Berninghausen, Roland Beckmann, Zoya Ignatova , Jürgen M. Plitzko, Daniel N. Wilson Nature Microbiology 3, 1115-1121 (2018) Reprint: bioRxiv 3, 382572 (39 pp) (2018) |
| 85 |
DNA Aptamers for the Malignant Transformation Marker CD24 Joanna Fafinska, Andreas Czech , Tobias Sitz, Zoya Ignatova , Ulrich Hahn Nucleic Acid Therapeutics 28, 326-334 (2018) |
| 84 |
Examining tRNA 3'-ends in Escherichia coli: A teamwork between CCA-adding enzyme, RNase T and RNase R Karolin Wellner, Andreas Czech , Zoya Ignatova , Heike Betat, Mario Mörl RNA 24, 361-370 (2018) |
| 83 |
Competition for amino acid flux among translation, growth and detoxification in bacteria Iolanda Ferro, Irina Chelysheva, Zoya Ignatova RNA Biology 15, 991-994 (2018) |
| 82 |
Heterogenität der molekularen Wirkung von Antibiotika und Anwendung der NGS-Technologie für die Antibiotikaentwicklung Zoya Ignatova Update Antibiotikaresistenz: Entstehung, Epidemiologie, Wirkstoffentwicklung 64-67 (2018), ISBN 978-3-7692-7113-3 , Verlag: Deutscher Apotheker Verlag |
2017 | |
| 81 |
Rewiring host activities for synthetic circuit production: a translation view Irem Avcilar-Kucukgoze, Zoya Ignatova Biotechnology Letters 39, 25-31 (2017) |
| 80 |
Systematic probing of the bacterial RNA structurome to reveal new functions Zoya Ignatova , Franz Narberhaus Current Opinion in Microbiology 36, 14-19 (2017) |
| 79 |
Growth-Rate Dependent Regulation of tRNA Level and Charging in Bacillus licheniformis Iolanda Ferro, Klaus Liebeton, Zoya Ignatova Journal of Molecular Biology 429, 3102-3112 (2017) |
| 78 |
Alteration of protein function by a silent polymorphism linked to tRNA abundance Sebastian Kirchner, Zhiwei Cai, Robert Rauscher, Nicolai Kastelic, Melanie Anding, Andreas Czech , Bertrand Kleizen, Lynda S. Ostedgaard, Ineke Braakman, David N. Sheppard, Zoya Ignatova PLoS Biology 15, e2000779 (29 pp) (2017) |
| 77 |
Microarray-Based Quantification of Cellular tRNAs Sebastian Kirchner, Robert Rauscher, Andreas Czech , Zoya Ignatova protocols.io Mar 29 (2017) |
| 76 |
Upregulating tRNAs in Mammalian Cells through Transfection of In Vitro Transcribed tRNAs Sebastian Kirchner, Robert Rauscher, Andreas Czech , Zoya Ignatova protocols.io Mar 29 (2017) |
| 75 |
tRNA Knock-Down in Mammalian Cells using Short Hairpin RNAs Sebastian Kirchner, Robert Rauscher, Andreas Czech , Zoya Ignatova protocols.io Mar 30 (2017) |
2016 | |
| 74 |
A minimal model of ribosome allocation dynamics captures trade-offs in expression between endogenous and synthetic genes Thomas E. Gorochowski , Irem Avcilar-Kucukgoze, Roel A. L. Bovenberg, Johannes A. Roubos, Zoya Ignatova ACS Synthetic Biology 5, 710-720 (2016) |
| 73 |
Mapping the non-standardized biases of ribosome profiling Alexander Bartholomäus, Cristian del Campo, Zoya Ignatova Biological Chemistry 397, 23-35 (2016) |
| 72 |
Influence of variability of translations - Intracellular speed - Regulation of protein synthesis by tRNAs Andreas Czech , Frauke Adamla, Zoya Ignatova BIOspektrum 22, 452-454 (2016) |
| 71 |
Insights into the adaptive response of Arabidopsis thaliana to prolonged thermal stress by ribosomal profiling and RNA-Seq Radoslaw Lukoszek, Peter Feist, Zoya Ignatova BMC Plant Biology 16, 221 (13 pp) (2016) |
| 70 |
Probing dimensionality beyond the linear sequence of mRNA Cristian del Campo, Zoya Ignatova Current Genetics 62, 331-334 (2016) |
| 69 |
An Expanded CAG Repeat in Huntingtin Causes +1 Frameshifting Paul Saffert, Frauke Adamla, Rico Schieweck, John F. Atkins, Zoya Ignatova Journal of Biological Chemistry 291, 18505-18513 (2016) |
| 68 |
Discharging tRNAs: a tug of war between translation and detoxification in Escherichia coli Irem Avcilar-Kucukgoze, Alexander Bartholomäus, Juan A. Cordero Varela, Robert Franz-Xaver Kaml, Peter Neubauer, Nediljko Budisa, Zoya Ignatova Nucleic Acids Research 44, 8324-8334 (2016) |
| 67 |
Bacteria differently regulate mRNA abundance to specifically respond to various stresses Alexander Bartholomäus, Ivan Fedyunin, Peter Feist, Celine Sin, Gong Zhang, Angelo Valleriani, Zoya Ignatova Philosophical Transactions of the Royal Society of London, Series A: Mathematical, Physical and Engineering Sciences 374, 20150069 (16 pp) (2016) |
2015 | |
| 66 |
Quantifying the 'escapers' among RNA species Iolanda Ferro, Zoya Ignatova Biochemical Society Transactions 43, 1215-1220 (2015) |
| 65 |
Tuning innate immunity by translation Robert Rauscher, Zoya Ignatova Biochemical Society Transactions 43, 1247-1252 (2015) |
| 64 |
A flexible approach to assess fluorescence decay functions in complex energy transfer systems Christoph Röthlein, Markus S. Miettinen, Zoya Ignatova BMC Biophysics 8, 5 (10 pp) (2015) |
| 63 |
Emerging roles of tRNA in adaptive translation, signalling dynamics and disease Sebastian Kirchner, Zoya Ignatova Nature Reviews Genetics 16, 98-112 (2015) |
| 62 |
Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate Thomas E. Gorochowski , Zoya Ignatova , Roel A. L. Bovenberg, Johannes A. Roubos Nucleic Acids Research 43, 3022-3032 (2015) |
| 61 |
Secondary Structure across the Bacterial Transcriptome Reveals Versatile Roles in mRNA Regulation and Function Cristian del Campo, Alexander Bartholomäus, Ivan Fedyunin, Zoya Ignatova PLoS Genetics 11, e1005613 (2015) |
| 60 |
Optimization of translation profiles enhances protein expression and solubility Anne-Katrin Hess, Paul Saffert, Klaus Liebeton, Zoya Ignatova PLoS One 10, e0127039 (2015) |
| 59 |
Somatic expression of unc-54 and vha-6 mRNAs declines but not pan-neuronal rgef-1 and unc-119 expression in aging Caenorhabditis elegans Frauke Adamla, Zoya Ignatova Scientific Reports 5, 10692 (2015) |
2014 | |
| 58 |
Stable Polyglutamine Dimers Can Contain β-Hairpins with Interdigitated Side Chains-But Not α-Helices, β-Nanotubes, β-Pseudohelices, or Steric Zippers Markus S. Miettinen, Luca Monticelli, Praveen Nedumpully-Govindan, Volker Knecht, Zoya Ignatova Biophysical Journal 106, 1721-1728 (2014) |
| 57 |
Architecture of polyglutamine-containing fibrils from time resolved fluorescence decay Christoph Röthlein, Markus S. Miettinen, Tejas Borwankar, Jörg Bürger, Thorsten Mielke, U. Kumke Michael, Zoya Ignatova Journal of Biological Chemistry 289, 26817-26828 (2014) |
| 56 |
GPER functions as a tumor suppressor in triple-negative breast cancer cells Christine Weißenborn, Tanja Ignatov, Hans-Joachim Ochel, Serban Dan Costa, Ana Claudia Zenclussen, Zoya Ignatova , Atanas Ignatov Journal of Cancer Research and Clinical Oncology 140, 713-723 (2014) |
| 55 |
Systematic identification of tRNAome and its dynamics in Lactococcus lactis Pranav Puri, Collin Wetzel, Paul Saffert, Kirk W. Gaston, Susan P. Russell, Juan A. Cordero Varela, Pieter van der Vlies, Gong Zhang, Patrick A. Limbach, Zoya Ignatova , Bert Poolman Molecular Microbiology 93, 944-956 (2014) |
2013 | |
| 54 |
Depletion of Cognate Charged Transfer RNA Causes Translational Frameshifting within the Expanded CAG Stretch in Huntingtin Hannah Girstmair, Paul Saffert, Sascha Rode, Andreas Czech , Gudrun Holland, Norbert Bannert, Zoya Ignatova Cell Reports 3, 148-159 (2013) |
| 53 |
Repetitive sequences - an obstacle for translation Paul Saffert, Zoya Ignatova DGZ Cell News 39 (2) 28-31 (2013) |
| 52 |
Interplay between polymerase II- and polymerase III-assisted expression of overlapping genes Radoslaw Lukoszek, Bernd Müller-Röber, Zoya Ignatova FEBS Letters 587, 3692-3695 (2013) |
| 51 |
Efficient translation initiation dictates codon usage at gene start Kajetan Bentele, Paul Saffert, Robert Rauscher, Zoya Ignatova , Nils Blüthgen Molecular Systems Biology 9, 675 (2013) |
| 50 |
Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress Andreas Czech , Sandra Wende, Mario Mörl, Tao Pan, Zoya Ignatova PLoS Genetics 9, e1003767 (2013) |
2012 | |
| 49 |
Crystallization and X-ray structure analysis of a thermostable penicillin G acylase from Alcaligenes faecalis Nishant Kumar Varshney, R. Suresh Kumar, Zoya Ignatova , Asmita Prabhune, Archana Pundle, Eleanor Dodson, C. G. Suresh Acta Crystallographica, Section F: Structural Biology and Crystallization Communications 68, 273-277 (2012) |
| 48 |
tRNA concentration fine tunes protein solubility Ivan Fedyunin, Lothar Lehnhardt, Nadine Boehmer, Paul Kaufmann, Gong Zhang, Zoya Ignatova FEBS Letters 586, 3336-3340 (2012) |
| 47 |
Polyglutamine Expansion Alters the Dynamics and Molecular Architecture of Aggregates in Dentatorubropallidoluysian Atrophy Justyna Hinz, Lothar Lehnhardt, Silke Zakrzewski, Gong Zhang, Zoya Ignatova Journal of Biological Chemistry 287, 2068-2078 (2012) Reprint: Journal of Visualized Experiments (2014) |
| 46 |
Assessing Polyglutamine Conformation in the Nucleating Event by Molecular Dynamics Simulations Markus S. Miettinen, Volker Knecht, Luca Monticelli, Zoya Ignatova Journal of Physical Chemistry B 116, 10259-10265 (2012) |
| 45 |
FANSe: an accurate algorithm for quantitative mapping of large scale sequencing reads Gong Zhang, Ivan Fedyunin, Sebastian Kirchner, Chuanle Xiao, Angelo Valleriani, Zoya Ignatova Nucleic Acids Research 40, e83 (2012) |
2011 | |
| 44 |
Natural Osmolytes Remodel the Aggregation Pathway of Mutant Huntingtin Exon 1 Tejas Borwankar, Christoph Röthlein, Gong Zhang, Anne Techen, Carsten Dosche, Zoya Ignatova Biochemistry 50, 2048-2060 (2011) |
| 43 |
Folding
at the birth of the nascent chain: Coordinating translation with co-translational folding Gong Zhang, Zoya Ignatova Current Opinion in Structural Biology 21, 25-31 (2011) |
| 42 |
Different sequence signatures in the upstream regions of plant and animal tRNA genes shape distinct modes of regulation Gong Zhang, Radoslaw Lukoszek, Bernd Müller-Röber, Zoya Ignatova Nucleic Acids Research 39, 3331-3339 (2011) |
| 41 |
Length-dependent translation of messenger RNA by ribosomes Angelo Valleriani, Gong Zhang, Apoorva Nagar, Zoya Ignatova , Reinhard Lipowsky Physical Review E: Statistical, Nonlinear, and Soft Matter Physics 83, 042903/1-042903/4 (2011) |
2010 | |
| 40 |
Turnover of messenger RNA: polysome statistics beyond the steady state Angelo Valleriani, Zoya Ignatova , Apoorva Nagar, Reinhard Lipowsky Europhysics Letters 89, 58003/p1-58003/p6 (2010) |
| 39 |
Silent mutations in sight: co-variations in tRNA abundance as a key to unravel consequences of silent mutations Andreas Czech , Ivan Fedyunin, Gong Zhang, Zoya Ignatova Molecular BioSystems 6, 1767-1772 (2010) |
| 38 |
Global and local depletion of ternary complex limits translational elongation Gong Zhang, Ivan Fedyunin, Oskar Miekley, Angelo Valleriani, Alessandro Moura, Zoya Ignatova Nucleic Acids Research 38, 4778-4787 (2010) |
| 37 |
Improved A. faecalis Penicillin Amidase Mutant Retains the Thermodynamic and pH Stability of the Wild Type Enzyme Ruslan Yuryev, Volker Kasche, Zoya Ignatova , Boris Galunsky Protein Journal 29, 181-187 (2010) |
2009 | |
| 36 |
An autonomous DNA model for finite state automata Israel Marck Martinez-Perez, Karl-Heinz Zimmermann, Zoya Ignatova International Journal of Bioinformatics Research and Applications 5, 81-96 (2009) |
| 35 |
Transient ribosomal attenuation coordinates protein synthesis and co-translational folding Gong Zhang, Magdalena Hubalewska, Zoya Ignatova Nature Structural & Molecular Biology 16, 274-280 (2009) |
| 34 |
Generic algorithm to predict the speed of translational elongation: Implications for protein biogenesis Gong Zhang, Zoya Ignatova PLoS One 4, e5036 (2009) |
| 33 |
Exploiting the features of the finite state automata for biomolecular computing Israel Marck Martinez-Perez, Zoya Ignatova , Karl-Heinz Zimmermann Recent Patents on DNA & Gene Sequences 3, 130-138 (2009) |
| 32 |
Isolation of homogeneous ribosome-nascent complexes from coupled cell-free transcription-translation system Gong Zhang, Zoya Ignatova Nature Protocols Published online 16 February 2009 (2009) |
| 31 |
A method for direct measurement of protein stability in vivo Zoya Ignatova , Lila M. Gierasch Methods in Molecular Biology 490 (Protein Structure, Stability, and Interactions) 165-178 (2009) |
2008 | |
| 30 |
Orthogonal Cross-Seeding: An Approach To Explore Protein Aggregates In Living Cells Justyna Hinz, Lila M. Gierasch, Zoya Ignatova Biochemistry 47, 4196-4200 (2008) |
| 29 |
DNA computing models Zoya Ignatova , Israel Marck Martinez-Perez, Karl-Heinz Zimmermann Seiten: 277 pp, ISBN 978-0-387-73637-2, Verlag: Springer Science+Business Media, New York (2008) |
| 28 |
A fluorescent window into protein folding and aggregation in cells Zoya Ignatova , Lila M. Gierasch Methods in Cell Biology 89 (Biophysical Tools for Biologists) 59-70 (2008) |
2007 | |
| 27 |
From the test tube to the cell: exploring the folding and aggregation of a β-clam protein Zoya Ignatova , Beena Krishnan, Jeffrey P. Bombardier, Anna Marie C. Marcelino, Jiang Hong, Lila M. Gierasch Biopolymers 88, 157-163 (2007) |
| 26 |
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype Israel Marck Martinez-Perez, Gong Zhang, Zoya Ignatova , Karl-Heinz Zimmermann BMC Bioinformatics 8, 365 (2007) |
| 25 |
In-cell Aggregation of a Polyglutamine-containing Chimera Is a Multistep Process Initiated by the Flanking Sequence Zoya Ignatova , Ashwani K. Thakur, Ronald Wetzel, Lila M. Gierasch Journal of Biological Chemistry 282, 36736-36743 (2007) |
| 24 |
Effects of osmolytes on protein folding and aggregation in cells Zoya Ignatova , Lila M. Gierasch Methods in Enzymology 428 (Osmosensing and Osmosignaling) 355-372 (2007) |
| 23 |
Implementation of biomolecular finite automata using nucleic acids in which transcription regulation and hybridization define transition rules, and sequences comprise input Karl-Heinz Zimmermann, Zoya Ignatova , Israel Marck Martinez-Perez -/- Anmelder: TuTech Innovation GmbH, Technische Universität Hamburg-Harburg Patent: DE 102006009000 (B3) 2007-09-06 |
2006 | |
| 22 |
Extended Polyglutamine Tracts Cause Aggregation and Structural Perturbation of an Adjacent β Barrel Protein Zoya Ignatova , Lila M. Gierasch Journal of Biological Chemistry 281, 12959-12967 (2006) |
| 21 |
Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant Zoya Ignatova , Lila M. Gierasch Proceedings of the National Academy of Sciences of the United States of America 103, 13357-13361 (2006) |
2005 | |
| 20 |
Aggregation of a Slow-Folding Mutant of a β-Clam Protein Proceeds through a Monomeric Nucleus Zoya Ignatova , Lila M. Gierasch Biochemistry 44, 7266-7274 (2005) |
| 19 |
Ca2+ Is a Cofactor Required for Membrane Transport and Maturation and Is a Yield-Determining Factor in High Cell Density Penicillin Amidase Production Volker Kasche, Zoya Ignatova , Herbert Märkl, Wilhelm Plate, Nils Punckt, Dorothea Schmidt, Katharina Wiegandt, Burkhard Ernst Biotechnology Progress 21, 432-438 (2005) |
| 18 |
Effect of the increased stability of the penicillin amidase mRNA on the protein expression levels Sandra C. Viegas, Dorothea Schmidt, Volker Kasche, Cecilia M. Arraiano, Zoya Ignatova FEBS Letters 579, 5069-5073 (2005) |
| 17 |
Biomolecular autonomous solution of the Hamiltonian path problem via hairpin formation Israel Marck Martinez-Perez, Gong Zhang, Zoya Ignatova , Karl-Heinz Zimmermann International Journal of Bioinformatics Research and Applications 1, 389-398 (2005) |
| 16 |
Pro-sequence and Ca2+-binding: Implications for Folding and Maturation of Ntn-hydrolase Penicillin Amidase from E. coli Zoya Ignatova , Frank Wischnewski, Holger Notbohm, Volker Kasche Journal of Molecular Biology 348, 999-1014 (2005) |
| 15 |
Monitoring protein stability in vivo Zoya Ignatova Microbial Cell Factories 4, 23 (2005) |
2004 | |
| 14 |
Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling Zoya Ignatova , Lila M. Gierasch Proceedings of the National Academy of Sciences of the United States of America 101, 523-528 (2004) |
| 13 |
Post-transcriptional and post-translational processes for regulation of protein function, activity and yield Zoya Ignatova Habilitationsschrift, TUHH 105 pp (2004) |
| 12 |
Mutant propenicillin amidase, its production with transgenic microorganisms, and it use in preparation of penicillin/cephalosporin precursors Volker Kasche, Zoya Ignatova , Boris Galunsky -/- Anmelder: TUHH Technologie GmbH, Technische Universität Hamburg-Harburg Patent: EP 1418230 (A2) 2004-05-12 |
2003 | |
| 11 |
Improvement of posttranslational bottlenecks in the production of penicillin amidase in recombinant Escherichia coli strains Zoya Ignatova , Anis H. Mahsunah, Maya Georgieva, Volker Kasche Applied and Environmental Microbiology 69, 1237-1245 (2003) |
| 10 |
Fragments of pro-peptide activate mature penicillin amidase of Alcaligenes faecalis Volker Kasche, Boris Galunsky, Zoya Ignatova European Journal of Biochemistry 270, 4721-4728 (2003) |
2002 | |
| 9 |
Unusual Signal Peptide Directs Penicillin Amidase from Escherichia coli to the Tat Translocation Machinery Zoya Ignatova , Claudia Hörnle, Alan Nurk, Volker Kasche Biochemical and Biophysical Research Communications 291, 146-149 (2002) |
2001 | |
| 8 |
Penicillin amidase: a model system to study the post-translational processes influencing the yield of periplasmic enzymes Zoya Ignatova -/- Betreuer: Volker Kasche Dissertation, TU Hamburg-Harburg (2001) |
2000 | |
| 7 |
Role of the intracellular proteolysis in the production of the periplasmic penicillin amidase in Escherichia coli Zoya Ignatova , Stefan Taruttis, Volker Kasche Biotechnology Letters 22, 1727-1732 (2000) |
| 6 |
The relative importance of intracellular proteolysis and transport on the yield of the periplasmic enzyme penicillin amidase in Escherichia coli Zoya Ignatova , Sven-Olof Enfors, Matthias Hobbie, Stefan Taruttis, Carsten Vogt, Volker Kasche Enzyme and Microbial Technology 26, 165-170 (2000) |
1999 | |
| 5 |
Isolation and partial characterization of extracellular keratinase from a wool degrading thermophilic actinomycete strain Thermoactinomyces candidus Zoya Ignatova , Adriana Gousterova, Grigor Spassov, Peter Nedkov Canadian Journal of Microbiology 45, 217-222 (1999) |
1998 | |
| 4 |
Proteolytic processing of penicillin amidase from Alcaligenes faecalis cloned in E. coli yields several active forms Zoya Ignatova , Stanka Stoeva, Boris Galunsky, Claudia Hörnle, Alan Nurk, Elke Piotraschke, Wolfgang Voelter, Volker Kasche Biotechnology Letters 20, 977-982 (1998) |
| 3 |
Decomposition of native keratin by thermophilic actinomycetes Zoya Ignatova , Adriana Gousterova, Grigor Spassov, Peter Nedkov Dokladi na Bulgarskata Akademiya na Naukite 51, 67-70 (1998) |
| 2 |
Comparison of dwell times for the amplification of DNA-fragments using different DNA polymerases Volker Kasche, Zoya Ignatova Thermal Cycling 3-4 (1998), Verlag: Hybaid, UK |
1997 | |
| 1 |
Temperature effects on S1- and S1'-enantioselectivity of α-chymotrypsin Boris Galunsky, Zoya Ignatova , Volker Kasche Biochimica et Biophysica Acta, Protein Structure and Molecular Enzymology 1343, 130-138 (1997) |