Fachbereich Chemie
Suche: FB Chemie / Hamburg | |
2024 | |
171 |
Vortrag: The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation Absender: Melad Henis (= Tabitha Rücker = Robin Scharrenberg = Melanie Richter = Lucas Baltussen = Shuai Hong = Durga Praveen Meka = Birgit Schwanke = Nagammal Neelagandan = Danie Daaboul = Nadeem Murtaza = Christoph Krisp = Sönke Harder = Hartmut Schlüter = Matthias Kneussel = Irm Hermans-Borgmeyer = Joris de Wit = Karun K. Singh = Kent E. Duncan = Froylan Calderón de Anda) Science Advances 10, eadf7001 (18 pp) (2024) Beschreibung: The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation |
170 |
present invention relates generally to vaccine for prophylaxis or treatment of infection by Lassa virus or of disorder relating to such infection Michael Jarvis, Thekla Mauch, Wolfram Brune , Eleonore Ostermann, Alec Redwood, Baca Chan, Andrew Davison, Jenna Nichols, Joseph Hughes, Matej Vucak, Heinrich Feldmann, Kyle Rosenke, Frederick Hansen, Nafomon Sogoba, Seydou Doumbia, Scott Nuismer, Peter Barry -/- Anmelder: The Vaccine Group LTD Patent: WO 2024115785 (A1) 2024-06-06 |
169 |
Synthetic DNA construct encoding suppressor tRNA Zoya Ignatova , Suki Albers-Fomenko , Marcos Davyt, Nikhil Bharti -/- Anmelder: Universität Hamburg Patent: WO 2024208970 (A2) 2024-10-10; EP 4442826 (A1) 2024-10-09 |
168 |
Pharmaceutical composition comprising multiple suppressor transfer RNAs Zoya Ignatova , Nikhil Bharti, Marcos Davyt -/- Anmelder: Universität Hamburg Patent: WO 2024227728 (A1) 2024-11-07; EP 4458967 (A1) 2024-11-06 |
2023 | |
167 |
Prefusion-stabilized herpesvirus glycoprotein-B for production of antibodies or therapeutic agents such as vaccines Kay Grünewald , Benjamin Vollmer, Marija Backovic, Maya Topf, Anna Hernández Durán, Victor Jefferys, Daven Vasishtan -/- Anmelder: Leibnitz Institut für Virologie, Institut Pasteur Patent: WO 2023046923 (A1) 2023-03-30; US 2023096087 (A1) 2023-03-30 |
166 |
Synthetic Transfer RNA with Modified Nucleotides Zoya Ignatova , Suki Albers -/- Anmelder: Universität Hamburg Patent: WO 2023118456 (A1) 2023-06-29; EP 4202045 (A1) 2023-06-28 |
2022 | |
165 |
Method for producing immunogenic composition of peptide sequences from at least one proteome of interest and uses thereof Sukrit Srivastava, Michael Kolbe Patent: IN 202011037585 (A) 2022-09-30 |
164 |
Multi-patch vaccines and immunogenic compositions, methods of production and uses thereof Sukrit Srivastava, Michael Kolbe -/- Anmelder: Helmholtz Zentrum Infektionsforschung GmbH Patent: WO 2022049595 (A1) 2022-03-10; EP 4208193 (A1) 2023-07-12 |
2020 | |
163 |
Animal luring device containing genetically engineered microorganisms producing attractant molecules, an active agent and a microbial nutrient source Daniel Wedemeyer, Henning Jacobsen, Alexander Kartheiser, Nina Patricia Kähler, Nele Burckhardt, Dustin Krüger, Martin Borowski, Alan Wypych, Nadine Fischer, Carla von Salisch, Oda-Emilia Meyfarth, Nico Domschke, Finni Speckenheuer, Bjarne Klopprogge, Roderich R. R. Meißner, Lisa Pütthoff, Nicole Freese, Markus Winkler, Lea Daniels, Dominika Wawrzyniak, Zoya Ignatova , Jonas Hoffmeister -/- Anmelder: Universität Hamburg Patent: WO 2020049118 (A1) 2020-03-12 |
162 |
Synthetic transfer RNA with extended anticodon loop Zoya Ignatova , Andrew E. Torda -/- Anmelder: Universität Hamburg Patent: WO 2020208169 (A1) 2020-10-15 |
2019 | |
161 |
Induction of allergen-specific Tregs prior to oral or sublingual immunotherapy of food allergy Reinhard Bredehorst, Thomas Grunwald, Catherine Leonard, Markus W. Ollert -/- Anmelder: Luxembourg Institure of Health, Tolerogenics S. A. R. L. Patent: WO 2019076477 (A1) 2019-04-25 |
160 |
Hydrogel-embedded oligodeoxynucleotides as tolerogenic adjuvant for subcutaneous immunotherapy Reinhard Bredehorst, Thomas Grunwald, Catherine Leonard, Markus W. Ollert , Bernhard Jungblut -/- Anmelder: Luxembourg Institure of Health, Tolerogenics S. A. R. L. Patent: WO 2019076478 (A1) 2019-04-25 |
159 |
Synthetic transfer RNA with extended anticodon loop Zoya Ignatova , Andrew E. Torda , Marco Matthies -/- Anmelder: Universität Hamburg Patent: WO 2019175316 (A1) 2019-09-19 |
2018 | |
158 |
Treatment of gynoid lipodystrophy Harry Frank Abts, Rainer Pooth, Martina Kerscher, Thomas Hengl, Birgit Blessmann-Gurk, Sabine Otto -/- Anmelder: MERZ PHARMA GMBH & CO KGAA Patent: WO 2018077825 (A1) 2018-05-03 |
2017 | |
157 |
Matrix-embedded tolerance-promotion adjuvants for subcutaneous immunotherapy Reinhard Bredehorst, Thomas Grunwald, Markus W. Ollert Patent: EP 3251662 (A1) 2017-12-06 |
156 |
Measurement cell for SAXS measurements and for dynamic light-scattering measurements Dmitri I. Svergun, Clement Blanchet, Daniel Franke, Melissa Gräwert, Florent Cipriani, Rob Meijers, Karsten Dierks, Annette Eckhardt, Arne Meyer, Christian Betzel , Sven Falke -/- Anmelder: European Molecular Biology Laboratory, Xtalconcepts GmbH, Universität Hamburg Patent: WO 2017067971 (A1) 2017-04-27; EP 3159674 (A1) 2017-04-26 |
155 |
DNA aptamer which binds α6 integrin Udo Schumacher, Tobias Lange, Daniel Wicklein, Ulrich Hahn , Katharina Redder Patent: WO 2017118458 (A1) 2017-07-13; DE 102016100039 (A1) 2017-07-06 |
2016 | |
154 |
Inhibition
der Bindung zwischen dem α 6 β 4 Integrin auf Prostatakrebszellen und rekombinantem Laminin-332 durch das α 6 Integrin spezifische DNA-Aptamer IDA Katharina Berg, Tobias Lange, Daniel Wicklein, Udo Schumacher, Ulrich Hahn -/- Anmelder: Universitätsklinikum Hamburg-Eppendorf, Universität Hamburg Patent: DE 102016100039 (A1) 2017-07-06 |
153 |
Antigen-specific immunotherapy using tolerizing liposomes Reinhard Bredehorst, Thomas Grunwald -/- Anmelder: PLS-Design GmbH Patent: EP 3095440 (A1) 2016-11-23; US 2016338955 (A1) 2016-11-24 |
2015 | |
152 |
DNA aptamers binding E- and P-selectins and their use in inhibiting cell adhesion in disease therapy Rassa Faryammanesh, Ulrich Hahn , Udo Schumacher, Daniel Wicklein -/- Anmelder: Universität Hamburg, Universitätsklinikum Hamburg-Eppendorf Patent: EP 2876163 A1 20150527 |
151 |
Induction of antigen-specific tolerance by peripheral phagocytosis Reinhard Bredehorst, Thomas Grunwald, Carsten Schmidt-Weber -/- Anmelder: PLS-Design GmbH, Helmholtz Zentrum München Forschungszentrum für Gesundheit und Umwelt GmbH Patent: EP 2918262 (A1) 2015-09-16; US 2015283231 (A1) 2015-10-08 |
150 |
Method of producing a preparation of membrane vesicles Kay Grünewald , Tzviya Zeev-Ben-Mordehai -/- Anmelder: Isis Innovation Patent: WO 2015011478 (A1) 2015-01-29 |
2014 | |
149 |
Selective local inhibition of TNFR1-mediated functions at the site of antigen/allergen presentation Reinhard Bredehorst, Thomas Grunwald, Markus W. Ollert , Carsten Schmidt-Weber, Edzard Spillner -/- Anmelder: PLS-Design GmbH, Klinikum rechts der Isar der TU München, Helmholtz Zentrum München Patent: EP 2746396 (A1) 2014-06-25 |
148 |
Low molecular weight immune-modulators as adjuvants for specific immunotherapy Reinhard Bredehorst, Thomas Grunwald, Markus W. Ollert , Carsten Schmidt-Weber -/- Anmelder: PLS-Design GmbH, Klinikum rechts der Isar der technischen Universität München, Helmholtz Zentrum München Forschungszentrum für Gesundheit und Umwelt GmbH Patent: WO 2014198420 (A1) 2014-12-18; EP 2813242 (A1) 2014-12-17; US 2016271257 (A1) 2016-09-22 |
147 |
Novel inhibitors of Protein kinase C ε signaling Johann Hofmann, Thierry Langer, Johannes Kirchmair , Florian Rechfeld, Peter Gruber, Markus Boehler, Georg Hechenberger, Dorota Garczarczyk, Maria N. Preobrazhenskaya, Gennady B. Lapa -/- Anmelder: Medizinische Universität Innsbruck, Universität Innsbruck, Gause Institute of New Antibiotics Patent: WO 2014207213 (A1) 2014-12-31 |
2013 | |
146 |
Pharmaceutical compositions comprising neuraminidase inhibitors for the treatment of influenza virus infection Johannes Kirchmair , Michaela Schmidtke, Klaus R. Liedl, Judith M. Rollinger -/- Anmelder: Universität Innsbruck Patent: EP 2599480 (A1) 2013-06-05 |
145 |
Controlled activation of complement components for use as endogenous adjuvant Reinhard Bredehorst, Thomas Grunwald, Markus W. Ollert , Carsten Schmidt-Weber, Edzard Spillner -/- Anmelder: PLS-Design GmbH, Klinikum rechts der Isar der TU München, Helmholtz Zentrum München Patent: EP 2674167 (A1) 2013-12-18 |
144 |
Modulation of effector T cell responses by local depletion of complement component C3 Reinhard Bredehorst, Thomas Grunwald, Markus W. Ollert , Carsten Schmidt-Weber, Edzard Spillner -/- Anmelder: PLS-Design GmbH, Klinikum rechts der Isar der TU München, Helmholtz Zentrum München Patent: EP 2674168 (A1) 2013-12-18 |
2012 | |
143 |
Mitte und Verfahren zur Modifizierung der 5'-Kappe von RNA Andrea Rentmeister , Daniela Schulz Patent: DE 102012222675 |
142 |
Dynamic light scattering and crystal nucleation control for monitoring of crystallization Christian Betzel , Rolf Hilgenfeld, Dierk Hilterhaus, Thomas Klupsch Patent: WO 2012000493 (A1) 2012-01-05; DE 102010025842 (A1) 2012-01-05 |
2011 | |
141 |
Recombinant vector containing infectious, viral genome sequences greater than 100 kb, method for producing same and use for the mutagenesis of the viral sequences Ulrich H. Koszinowski, Martin Messerle, Wolfram Brune , Gabriele Hahn Patent: US 7892822 (B1) 2011-02-22 |
140 |
Biocompatible magnetic nanoparticles for treating glioblastomae Birte Mucha, Regine Willumeit , Katrin Lamszus Patent: WO 2011058018 (A2) 2011-05-19; EP 2322142 (A1) 2011-05-18 |
139 |
RNA aptamers that specifically bind to sol. interleukin-6 receptor, and their therapeutic and diagnostic uses Ulrich Hahn , Stefan Rose-John, Cindy Meyer, Tijana Zivkovic Patent: WO 2011069486 (A1) 2011-06-16; DE 102009056944 (A1) 2011-06-09 |
138 |
DNA aptamers that specifically bind to sol. interleukin-6 receptor, and their therapeutic and diagnostic uses Ulrich Hahn , Stefan Rose-John, Cindy Meyer, Tijana Zivkovic Patent: WO 2011069487 (A2) 2011-06-16; DE 102009056945 (A1) 2011-06-16 |
2009 | |
137 |
Apparatus and method for uniform distribution of microparticles in a liquid Hartmut Schlüter , Joachim Thiemann, Jörg Feldhusen, Johannes Lemburg -/- Anmelder: Charité-Universitätsmedizin Berlin Patent: DE 102007047478 A1 2009-04-16 |
136 |
Antibody compositions specific for IgE, IgG4 and IgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy Ingke Braren, Reinhard Bredehorst, Markus W. Ollert , Thomas Grunwald, Johannes Ring, Edzard Spillner Patent: EP 2022507 (A1) 2009-02-11 |
135 |
Apparatus and method for uniform distribution of microparticles in a liquid Jörg Feldhusen, Hartmut Schlüter , Joachim Thiemann, Johannes Lemburg -/- Anmelder: Charité-Universitätsmedizin Berlin, RWTH Aachen Patent: WO 2009043813 (A1) 2009-04-09 |
2008 | |
134 |
Verfahren zur Identifikation von Urotensin-2Konvertase-Inhibitoren (Enzymes using urotensin II precursors as substrates and methods of screening for inhibitors) Joachim Thiemann, Hartmut Schlüter , Walter Zidek, Sandra Kurzawski -/- Anmelder: Charité-Universitätsmedizin Berlin Patent: DE 102006049822 (A1) 2008-04-24 |
133 |
Antimicrobial peptides Sylvie E. Blondelle, Roman Jerala, Primoz Pristovsek, Andreja Majerle, Mateja Zorko, Bostjan Japelj, Klaus Brandenburg , Jörg Andrä , Massimo Porro, Ignacio Moriyón Uría, José Leiva León, Guillermo Martinez de Tejada, Dagmar Zweytick, Günter Deutsch, Karl Lohner Patent: WO 2008006125 (A1) 2008-01-17 |
132 |
lepA as a target for antibacterial agents Knud H. Nierhaus, Yan Qin, Daniel N. Wilson -/- Anmelder: Max-Planck-Gesellschaft Patent: WO 2008046584 (A2) 2008-04-24 |
131 |
Method for identifying urotensin 2 convertase inhibitors Joachim Thiemann, Hartmut Schlüter , Walter Zidek, Sandra Kurzawski, Maria Trusch -/- Anmelder: Charité-Universitätsmedizin Berlin Patent: WO 2008046665 (A2) 2008-04-24 |
2007 | |
130 |
Implementation of biomolecular finite automata using nucleic acids in which transcription regulation and hybridization define transition rules, and sequences comprise input Karl-Heinz Zimmermann, Zoya Ignatova , Israel Marck Martinez-Perez -/- Anmelder: TuTech Innovation GmbH, Technische Universität Hamburg-Harburg Patent: DE 102006009000 (B3) 2007-09-06 |
129 |
Bivalent IgY antibody constructs for diagnostic and therapeutic applications Reinhard Bredehorst, Kerstin Greunke, Thomas Grunwald, Edzard Spillner Patent: EP 1757622 (A1) 2007-02-28 |
128 |
Chimeric proteins comprising human FcεRIα and avian IgY constant domain for detecting serum IgE and diagnosing allergy Ingke Braren, Reinhard Bredehorst, Thomas Grunwald -/- Anmelder: PLS-Design GmbH Patent: EP 1777524 (A1) 2007-04-25 |
127 |
Method for determining an unknown PNA [peptide nucleic acid] sequence and uses thereof Reinhard Bredehorst, Jörn Glökler, Thomas Grunwald, Mark Matzas, Edzard Spillner Patent: EP 1785490 (A1) 2007-05-16 |
126 |
Use of lepA G protein for improving the accuracy of protein synthesis in-vitro Knud H. Nierhaus, Yan Qin, Daniel N. Wilson -/- Anmelder: Max-Planck-Gesellschaft Patent: WO 2007003410 (A1) 2007-01-11 |
2006 | |
125 |
Sequence of a novel human p53 splice variant displaying differential transcriptional activity Wolfgang Deppert , Irene Dornreiter Patent: US 20060062792 (A1) 2006-03-23 |
124 |
Method for discovering suitable chromatography conditions for the separation of biological molecules Hartmut Schlüter Patent: US 2006096924 (A1) 2006-05-11 |
123 |
Screening method for ribosome recycling inhibitor Daniel N. Wilson , Frank Schluenzen, Joerg M. Harms, Renate Albrecht, Jörg Bürger, Takuya Yoshida, Tadayasu Ohkubo, Yuji Kobayashi, Paola Fucini -/- Anmelder: Osaka University, Max-Planck-Gesellschaft Patent: WO 2006059807 (A1) 2006-06-08 |
2005 | |
122 |
Fluorometric method for monitoring the production of biomolecule crystals Christian Betzel , Karsten Dierks, Gert Rapp Patent: US 20050172887 (A1) 2005-08-11 |
121 |
Complement depletion using recombinant human C3-derivatives Johanna Kölln, Reinhard Bredehorst, Edzard Spillner Patent: WO 2005003159 (A1) 2005-01-13 |
2004 | |
120 |
Mutant propenicillin amidase, its production with transgenic microorganisms, and it use in preparation of penicillin/cephalosporin precursors Volker Kasche, Zoya Ignatova , Boris Galunsky -/- Anmelder: TUHH Technologie GmbH, Technische Universität Hamburg-Harburg Patent: EP 1418230 (A2) 2004-05-12 |
119 |
Human p53 splice variant displaying differential transcriptional activity and its uses in tumor diagnosis and treatment Wolfgang Deppert , Irene Dornreiter -/- Anmelder: Wolfgang Deppert Patent: EP 1462521 (A1) 2004-09-29 |
118 |
Method for selecting chromatographic stationary phases for biomolecule separations Hartmut Schlüter -/- Anmelder: Charité-Universitätsmedizin Berlin Patent: WO 2004028658 (A1) 2004-04-08 |
117 |
Method for following protein extract purification and for identifying enzyme activities of fractions Hartmut Schlüter , Joachim Jankowski -/- Anmelder: Charité-Universitätsmedizin Berlin Patent: WO 2004029286 (A2) 2004-04-08 |
2002 | |
116 |
System and method for detecting and quantifying nucleic acids using covalent binding Reinhard Bredehorst, Rainer Hintsche, Anton Heuberger Patent: WO 2002081738 (A2) 2002-10-17 |
115 |
Non-enzymatic liposome-linked closely spaced array electrodes assay (NEL-ELA) for detecting and quantifying nucleic acids Reinhard Bredehorst, Rainer Hintsche, Anton Heuberger Patent: WO 2002081739 (A2) 2002-10-17 |
114 |
Activated
enzyme-linked detection systems for detecting and quantifying nucleic acids, antigens, antibodies and other analytes Reinhard Bredehorst, Rainer Hintsche, Anton Heuberger Patent: WO 2002082078 (A2) 2002-10-17 |
2001 | |
113 |
Eukaryote cell transformation using cytomegalovirus-based bacterial artificial chromosome vector system Markus Wagner, Wolfram Brune Patent: DE 10020500 (A1) 2001-10-31 |
112 |
Ligand-regulated self-cleaving RNA sequences inserted into the untranslated regions of mRNA and their use in the control of translation Nicolas Piganeau, Michael Famulok, Vincent Thuillier Patent: EP 1092777 (A1) 2001-04-18 |
2000 | |
111 |
Method for the production of planar microarrays of immobilized molecules by using microcompartments Reinhard Bredehorst, Reiner Hintsche, Rene Seitz, Walter Gumbrecht Patent: DE 19916867 (A1) 2000-10-19 |
110 |
A transgenic mouse with a prolactin-inducible oncogene for use as a model of ductal carcinoma in situ Christine Schulze-Garg, Wolfgang Deppert -/- Anmelder: Mice & More GmbH & CO KG, Christine Schulze-Garg, Wolfgang Deppert Patent: WO 2000044889 (A2) 2000-08-03 |
109 |
Classification of bacteria using sequences of gyr and par genes Peter Heisig, Yolanda Fuchs-Gomez Patent: WO 2000061796 (A1) 2000-10-19 |
108 |
Method for the preparation of electronic sensor arrays and their application as electrochemical transducers in DNA chips Jörg Albers, Helmut Bernt, Reinhard Bredehorst, Rainer Hintsche, Rene Seitz Patent: WO 2000062047 (A1) 2000-10-19 |
107 |
Sensor arrays with ultramicroelectrodes for biochemical affinity assays Jörg Albers, Helmut Bernt, Reinhard Bredehorst, Rainer Hintsche, Rene Seitz Patent: WO 2000062048 (A2) 2000-10-19 |
1999 | |
106 |
Hemmung der durch mutiertes p53 verursachten Modulation von DNA (Inhibiting DNA modulation caused by p53 mutant, useful for treatment of cancer) Wolfgang Deppert Patent: DE 19802792 (A1) 1999-07-29 |
105 |
Novel cobra venom factors and their use in lowering complement activity via recombinant proCVF Carl-Wilhelm Vogel, Reinhard Bredehorst, David C. Fritzinger, Michael A. Kock Patent: US 5922320 (A) 1999-07-13 |
104 |
In vivo binding pair pretargeting with antibodies and methotrexate analogs Nicholas Pomato, Richard P. McCabe, Gregory A. Hawkins, Reinhard Bredehorst, Chong-Ho Kim, Carl-Wilhelm Vogel Patent: US 5965106 (A) 1999-10-12 |
103 |
Method for influencing p53 binding to promoter regions of target genes using modulators of DNA and protein conformation Wolfgang Deppert , Ella L. Kim Patent: WO 9908712 (A2) 1999-02-25 |
102 |
Processes and kits for mass spectrometric determination of polypeptides Daniel P. Little, Hubert Köster, G. Scott Higgins, David M. Lough -/- Anmelder: Sequenom Inc Patent: WO 9912040 (A2) 1999-03-11 |
101 |
Mass spectrometric methods for nucleic acid sequencing Maryanne J. O'Donnell, Changwon Kang, Young-Soo Kwon, Young Tae Kim, Hubert Köster, Daniel P. Little, Guobing Xiang, David M. Lough, Charles R. Cantor -/- Anmelder: Sequenom Inc, Korea Advanced Institute of Science and Technology, Maryanne J. O'Donnell Patent: WO 9931278 (A1) 1999-06-24 |
100 |
Solution phase biopolymer synthesis of oligodeoxyribonucleotides using multifunctional liq. phase carriers Hubert Köster, Ralf Wörl Patent: WO 9955718 (A2) 1999-11-04 |
99 |
Infrared matrix-assisted laser desorption/ionization mass spectrometric analysis of biomacromolecules Franz Hillenkamp, Hubert Köster -/- Anmelder: Sequenom Inc, Franz Hillenkamp, Hubert Köster Patent: WO 9957318 (A2) 1999-11-11 |
1998 | |
98 |
Protease-derivatized cobra venom factor with retention of bioactivity Markus W. Ollert , Patrick Ziegelmüller, Thomas Grunwald, Reinhard Bredehorst, Carl-Wilhelm Vogel Patent: US 5714344 (A) 1998-02-03 |
97 |
Compositions and methods for immobilizing macromolecules on solid supports David M. Lough, Hubert Köster, Dirk Reuter, G. Scott Higgins -/- Anmelder: Sequenom Inc, David M. Lough, Hubert Köster, Dirk Reuter, G. Scott Higgins Patent: WO 9820019 (A1) 1998-05-14 |
96 |
High density immobilization of nucleic acids and apparatus for dispensing nanovolumes of liquids and formation of multielement arrays Maryanne J. O'Donnell, Charles R. Cantor, Daniel P. Little, Hubert Köster -/- Anmelder: Sequenom Inc, Maryanne J. O'Donnell, Charles R. Cantor, Daniel P. Little, Hubert Köster Patent: WO 9820020 (A2) 1998-05-14 |
95 |
DNA sequencing diagnostics based on mass spectrometry Hubert Köster, Kai Tang, Dong-Jing Fu, Carsten W. Siegert, Daniel P. Little, G. Scott Higgins, Andreas Braun, Brigitte Damhoffer-Demar, Christian Jurinke, Dirk van der Boom, Guobing Xiang, David M. Lough -/- Anmelder: Sequenom Inc, Hubert Köster, Kai Tang, Dong-Jing Fu, Carsten W. Siegert, Daniel P. Little, G. Scott Higgins, Andreas Braun, Brigitte Damhoffer-Demar, Christian Jurinke, Dirk van den Boom, Guobing Xiang, David M. Lough Patent: WO 9820166 (A2) 1998-05-14 |
94 |
A reversible conjugation of biomolecules to solid supports for nucleic acid sequencing, amplification and detection Hubert Köster Patent: WO 9833808 (A2) 1998-08-06 |
1997 | |
93 |
DNA detection and diagnostics based on mass spectrometry Hubert Köster -/- Anmelder: Sequenom Inc Patent: US 5605798 (A) 1997-02-25 |
92 |
Apparatus and process for multi-stage solid-phase synthesis of long-chained organic molecules Stephen Allen, Hubert Köster, Edward Ashare, Donald W. Euwart, Jennifer Fernandes -/- Anmelder: Hybridon Inc Patent: WO 9707126 (A1) 1997-02-27 |
91 |
A method for processing large number of samples to isolate plasmids using a filtration procedure Hubert Köster Patent: WO 9708306 (A1) 1997-03-06 |
90 |
Nucleic acid sequencing by mass spectrometry Hubert Köster -/- Anmelder: Sequenom Inc Patent: WO 9737041 (A2) 1997-10-09 |
89 |
A combinatorial protecting group strategy for the solid phase preparation of oligodeoxyribonucleotides Hubert Köster, Eckart Leikauf Patent: WO 9741139 (A2) 1997-11-06 |
88 |
Direct sequencing of DNA during enzymic amplification of the template using pairs of DNA polymerases with different affinities for chain-terminating nucleotides Hubert Köster, Dirk van den Boom, Andreas Ruppert -/- Anmelder: Sequenom Inc Patent: WO 9742348 (A1) 1997-11-13 |
87 |
Method for dissociating biotin complexes Christian Jurinke, Dirk van den Boom, Hubert Köster -/- Anmelder: Sequenom Inc Patent: WO 9743617 (A2) 1997-11-20 |
1996 | |
86 |
Sanger DNA sequencing by mass spectrometry using base-specific chain termination and elongation, primer modification, nested fragments, reversible immobilization, and tag-specific probes Hubert Köster -/- Anmelder: Sequenom Inc Patent: US 5547835 (A) 1996-08-20 |
85 |
In vivo binding pair pretargeting using targeting moiety-affinity component conjugate and affinity component binding partner-functional moiety conjugate Nicholas Pomato, Richard P. McCabe, Gregory A. Hawkins, Reinhard Bredehorst, Chong-Ho Kim, Carl-Wilhelm Vogel Patent: US 5578289 (A) 1996-11-26 |
84 |
High-yield manufacture of water-soluble dimeric to decameric chitin oligomers Reinhard Bredehorst, Nicholas Pomato, Oliver Scheel, Joachim Thiem -/- Anmelder: AKZO Nobel NV, Reinhard Bredehorst, Nicholas Pomato, Oliver Scheel, Joachim Thiem Patent: WO 9626965 (A1) 1996-09-06 |
83 |
Fast, reliable, and accurate method for detection of nucleic acid in biological sample by nucleic acid isolation, amplification, and mass spectrometry Hubert Köster -/- Anmelder: Sequenom Inc Patent: WO 9629431 (A2) 1996-09-26 |
82 |
Methods and kits nucleic acid detection and sequencing, especially using mass-modified nucleic acid probe arrays Charles R. Cantor, Hubert Köster, Cassandra L. Smith, Dong-Jing Fu -/- Anmelder: Boston University Patent: WO 9632504 (A2) 1996-10-17 |
1995 | |
81 |
Konjugat zur Induktion zellulärer Immunität (Conjugate containing a non-immunogenic carrier and a CD8+ T cell epitope for inducing cellular immunity especially against lymphocytic choriomeningitis virus) Wolfgang Deppert Patent: DE 4435086 (C1) 1995-08-10 |
80 |
Protease-derivatized cobra venom factor Markus W. Ollert , Patrick Ziegelmüller, Thomas Grunwald, Reinhard Bredehorst, Carl-Wilhelm Vogel Patent: WO 9507299 (A1) 1995-03-16 |
1994 | |
79 |
DNA sequencing by mass spectrometry Hubert Köster Patent: WO 9416101 (A2) 1994-07-21 |
78 |
DNA sequencing by mass spectrometry of exonuclease-generated sequential degradation products Hubert Köster Patent: WO 9421822 (A1) 1994-09-29 |
77 |
Molecular cloning of cDNA for cobra complement C3 and its analogs CVF1 and CVF2 David C. Fritzinger, Reinhard Bredehorst, Carl-Wilhelm Vogel Patent: WO 9423024 (A1) 1994-10-13 |
1993 | |
76 |
In vivo binding pair pretargeting for site-specific delivery of functional moiety in radioimaging or radiotherapy Nicholas Pomato, Richard P. McCabe, Gregory A. Hawkins, Reinhard Brederhorst, Chong-Ho Kim, Carl-Wilhelm Vogel Patent: WO 9317707 (A1) 1993-09-16 |
1991 | |
75 |
Immobilization of proteins and peptides on insoluble supports for sequencing and other applications Darryl J. C. Pappin, James M. Coull, Hubert Köster -/- Anmelder: Millipore Corp Patent: EP 410323 (A2) 1991-01-30 |
74 |
Reversible
modification of biological compounds for detection, separation and purification thereof James M. Coull, Brian D. Gildea, Hubert Köster -/- Anmelder: Millipore Corp Patent: EP 424819 (A1) 1991-05-02 |
73 |
Immobilization of active agents on hydroxyl group-carrying substrates with a silane and heterobifunctional crosslinking agent Frances S. Eigler, Jacque Georger, Suresh K. Bhatia, Jeff Calvert, Lisa C. Shriver-Lake, Reinhard Bredehorst Patent: US 5077210 (A) 1991-12-31 |
72 |
Ligand-label conjugates which contain polyoxoanions of sulfur or phosphorus Reinhard Bredehorst, Frances S. Ligler, Anne W. Kusterbeck, Gregory A. Wemhoff, Carl-Wilhelm Vogel Patent: WO 9116344 (A1) 1991-10-31 |
1990 | |
71 |
Membranes for solid phase protein sequencing James M. Coull, Darryl J. C. Pappin, Hubert Köster, Malcolm G. Pluskal, Michael J. Steuck, Alex G. Bonner -/- Anmelder: Millipore Corp Patent: EP 353460 (A2) 1990-02-07 |
70 |
Site-specific in-vivo activation of prodrugs Reinhard Bredehorst, Chong-Ho Kim, Richard P. McCabe, Nicholas Pomato, Carl-Wilhelm Vogel Patent: WO 9007929 (A1) 1990-07-26 |
69 |
Preparation of site-specific heterobifunctional crosslinking reagents, their use, and kits containing them Jane J. Zara, Richard D. Wood, Reinhard Bredehorst, Carl-Wilhelm Vogel Patent: WO 9010621 (A1) 1990-09-20 |
68 |
Detecting and sequencing nucleic acids using chemiluminescence Stephan Beck, James M. Coull, Hubert Köster, Thomas O'Keeffe -/- Anmelder: Millipore Corp Patent: WO 9010718 (A1) 1990-09-20 |
1989 | |
67 |
Preparation of modified polymer membranes as supports for the solid phase synthesis of oligonucleotides and peptides Hubert Köster, James M. Coull -/- Anmelder: Millipore Corp Patent: EP 305929 (A2) 1989-03-08 |
1988 | |
66 |
Synthetic food protein genes and their expression, and use of the protein in diets for treatment of liver insufficiency and phenylketonuria Hubert Köster, Jacek Biernat, Nick Kennedy, Bernd Hofer -/- Anmelder: Biosyntech GmbH Patent: EP 285675 (A1) 1988-10-12 |
65 |
Detectably labeled cephalosporin assay for β-lactamase determination Reinhard Bredehorst, Abdolhossen Talebian, Charles F. Hammer, Carl-Wilhelm Vogel Patent: US 4764462 (A) 1988-08-16 |
1987 | |
64 |
Antirheumatic coated particles for oral administration Werner Thorn Patent: EP 243521 (A1) 1987-11-04 |
1986 | |
63 |
Oral verabreichbare Zusammensetzung (Preservatives for orally-dispensable compositions) Werner Thorn Patent: DE 3434885 (A1) 1986-03-27 |
1985 | |
62 |
Verfahren zur Festlegung des Funktionszustandes der Niere (Method for establishing the functional state of the kidney) Ferdinand Liemann Patent: DE 3308346 (A1) 1985-01-31 |
61 |
Verfahren zur definierten Verknüpfung doppelhelikaler DNA-Fragmente mittels einer Linker-DNA sowie als Linker-DNA geeignete Oligonucletide (Defined connected double helical DNA-fragments by means of a linkage DNA as well as linkage DNA-suitable oligonucleotides) Hubert Köster Patent: DE 3326520 (A1) 1985-01-31 |
60 |
Oligonucleotides Hubert Köster, Nanda D. Sinha -/- Anmelder: Hubert Köster Patent: DE 3329892 (A1) 1985-03-07 |
1984 | |
59 |
Präparat mit Hilfssubstanz zur Bekämpfung von Nebenwirkungen (Preparation with an auxiliary substance for controlling drug-induced side effects) Werner Thorn Patent: DE 2858001 (C1) 1984-09-27 |
58 |
Verfahren zur Herstellung von Oligonucleotiden (Oligonucleotides) Hubert Köster Patent: DE 3239887 (A1) 1984-05-03 |
57 |
Verfahren zur Herstellung von Oligonucleosidphosphonaten (Oligonucleoside phosphonates) Hubert Köster Patent: DE 3239888 (A1) 1984-05-03 |
56 |
Verfahren zum Testen von chemischen und biologischen Substanzen (Testing of chemical and biological substances) Werner Thorn, Walter Johann Ziegler Patent: DE 3327248 (C1) 1984-12-20 |
1983 | |
55 |
Verfahren zur Abspaltung von Tritylschutzgruppen (Cleavage of trityl protective groups) Hubert Köster, Nanda D. Sinha -/- Anmelder: Hubert Köster Patent: DE 3208565 (A1) 1983-11-10 |
1982 | |
54 |
Oral verabreichbares pharmazeutisches Präparat (Oral acetylsalicylic acid preparations) Werner Thorn, Manfred Puschmann Patent: DE 3123259 (A1) 1982-12-30 |
1979 | |
53 |
Use of malonic acid diesters and O-acyltartronic acid diesters as lipase inhibitors Günther Gercken, Brigitte Moll, Wolfgang Meyer Patent: DE 2806804 (A1) 1979-08-23 |
52 |
Verfahren zum Testen von chemischen und biologischen Substanzen (Testing of chemical and biological substances) Werner Thorn Patent: DE 2810425 (A1) 1979-09-20 |
51 |
Verfahren zum Testen von chemischen und biologischen Substanzen (Testing of chemical and biological substances) Werner Thorn Patent: DE 2819127 (A1) 1979-10-31 |
1977 | |
50 |
Verfahren zur Herstellung von Camptothecin-ähnlichen Verbindungen (Camptothecine and related compounds) Karsten Krohn, Ekkehard Winterfeldt -/- Anmelder: BASF AG Patent: DE 2534601 (A1) 1977-02-17 |
1976 | |
49 |
Auf den biologisch aktiven Bereich des ACTH-Moleküls gerichteter Antikörper für einen Radioimmunoassay und Verfahren zu seiner Herstellung (Antibodies for the biologically active area of the ACTH molecule for use in a radioimmunoassay) Ferdinand Liemann, Marianne Pilaksi -/- Anmelder: Marianne Pilaksi Patent: DE 2442569 (A1) 1976-03-18 |
1971 | |
48 |
Verfahren zur Aufschließung und Weiterverarbeitung von Klärschlämmen (Treatment of sewage sludge) Werner Thorn Patent: DE 1935229 (A) 1971-02-04 |
47 |
Verfahren zur Aufschließung und Weiterverarbeitung von Klärschlämmen (Slime digestion and lime treatment of - concentrate ) Werner Thorn Patent: DE 1947492 (A) 1971-04-01 |
46 |
Verfahren zur Aufschließung und Weiterverarbeitung von Klärschlämmen (Disintegration and subsequent treatment of settling slimes) Werner Thorn Patent: DE 1956107 (A) 1971-06-24 |
45 |
Verfahren zur Aufschließung und Weiterverarbeitung von Frisch- und Faulschlämmen (Decomposition and reprocessing of fresh and putrid sludge) Werner Thorn Patent: DE 2020304 (A) 1971-11-18 |
1970 | |
44 |
Verfahren zur Fällung von hochmolekularen Stoffen mit basischen Gruppen aus Abwässern bzw. zur Anreicherung aus Lösungen sowie die Verwendung der Fällungsprodukte (Precipitation from waste water of high molecular weight material with basic groups, of animal, plant or microbial origin, and use of the precipitated products) Werner Thorn, Bent Simonsen Patent: DE 1807967 (A) 1970-08-27 |
43 |
Verfahren zur Gewinnung von hochmolekularen Stoffen mit basischen Gruppen aus Abwässern (Recovery of high-molecular-weight materials containing basic groups from waste water) Werner Thorn Patent: DE 1913019 (A) 1970-09-17 |
1965 | |
42 |
Verfahren zur Herstellung von entzündungs- und ödemhemmenden Salzen der Pentadecen- und Heptadecensäuren (Inflammation- and edema-retarding salts of cis-9-pentadecenoic acid and cis-9-heptadecenoic acid) Gernot Grimmer Patent: DE 1186048 (B) 1965-01-28 |
41 |
Verfahren zur Herstellung von entzündungs- und ödemhemmenden Salzen der Pentadecen- und Heptadecensäuren (Pentadecenoic and heptadecenoic acids salts) Gernot Grimmer -/- Anmelder: Gernot Grimmer, Walter Sturm Patent: DE 1186049 (B) 1965-01-28 |
40 |
Verfahren zur Herstellung von entzuendungs- und oedemhemmenden Salzen der cis-9-Pentadecensaeure und der cis-9-Heptadecensaeure (Inflammation- and edema-retarding salts of cis-9-pentadecenoic acid and cis-9-heptadecenoic acid) Gernot Grimmer Patent: DE 1195296 (B) 1965-06-24 |
1963 | |
39 |
Verfahren zur Herstellung von 1-Phenyl-1-hydroxy-2-halogen-propanen (1-Phenyl-1-hydroxy-2-halopropanes) Gernot Grimmer Patent: DE 1148535 (B) 1963-05-16 |
1961 | |
38 |
Antiphlogistically active salts of cis-Δ9-heptadecenoic acid and cis-Δ9-pentadecenoic acid Gernot Grimmer, Walter Sturm Patent: GB 858621 (A) 1961-01-11 |
1959 | |
37 |
Verfahren zur Herstellung von Abkömmlingen von Sulfonamiden der Pyrimidinreihe (Pyrimidinesulfonamides) Rudolf Tschesche, Hermann Fox -/- Anmelder: Schering AG Patent: DE 971656 (C) 1959-03-12 |
36 |
Verfahren zur Herstellung von Abkömmlingen von Sulfonamiden der Pyrimidinreihe (Pyrimidinesulfonamides) Rudolf Tschesche, Hermann Fox -/- Anmelder: Schering AG Patent: DE 972507 (C) 1959-08-06 |
1958 | |
35 |
Verfahren zur Herstellung neuer herzwirksamer Verbindungen (Cardiac active compounds) Fritz Kaiser, Gernot Grimmer -/- Anmelder: C.F. Boehringer & Soehne GmbH Patent: DE 1026312 (B) 1958-03-20 |
1956 | |
34 |
Verfahren zur Herstellung von p-Aminobenzolsulfonamid-Abkömmlingen (p-Aminobenzenesulfonamide derivatives) Rudolf Tschesche, Hermann Fox -/- Anmelder: Schering AG Patent: DE 944731 (C) 1956-06-21 |
1954 | |
33 |
Verfahren zur Darstellung von 6-Amino-9-oxy-folsäure (6-Amino-9-hydroxyfolic acid) Rudolf Tschesche, Sigmund Zakrzewski -/- Anmelder: Nordmark Werke GmbH Patent: DE 921698 (C) 1954-12-23 |
1953 | |
32 |
Verfahren
zur Herstellung von 9-Oxypteroinsäure oder 9-Oxypteroinsäurederivaten, insbesondere 9-Oxypteroylglutaminsäure (9-Oxyfolinsäure) (9-Hydroxypteroic acid and its derivatives, especially 9-hydroxypteroylglutamic acid) Rudolf Tschesche, Friedhelm Korte, Carl-Heinz Köhncke -/- Anmelder: Schering AG Patent: DE 869960 (C) 1953-03-09 |
31 |
Verfahren zur Darstellung von Pteroinsäure oder Pteroinsäurederivaten, insbesondere Pteroylglutaminsäure (Folinsäure) (Pteroylglutamic acid) Rudolf Tschesche, Friedhelm Korte -/- Anmelder: Schering AG Patent: DE 869961 (C) 1953-03-09 |
30 |
Verfahren zur Herstellung von Abkömmlingen des 4-Oxypiperidins (Derivatives of 4-hydroxypiperidine) Rudolf Tschesche, Hermann Fox, Karl Junkmann -/- Anmelder: Schering AG Patent: DE 872045 (C) 1953-03-30 |
29 |
Verfahren zur Herstellung von 9-Oxypteroinsäure oder 9-Oxypteroin-säurederivaten, insbesondere 9-Oxypteroylglutaminsäure (9-Oxyfolinsäure) (9-Hydroxypteroic acid and its derivatives) Rudolf Tschesche, Friedhelm Korte -/- Anmelder: Schering AG Patent: DE 887812 (C) 1953-08-27 |
28 |
Verfahren zur Herstellung von Pteroinsäuren Viktor Wolf, Friedhelm Korte -/- Anmelder: Nordmark Werke GmbH Patent: DE 899355 (C) 1953-12-10 |
27 |
7-hydroxypteridines Rudolf Tschesche -/- Anmelder: Nordmark Werke GmbH Patent: US 2632760 (A) 1953-03-24 |
1952 | |
26 |
Verfahren zur Darstellung von 8-Halogenmethyl-, insbesondere 8-Brom-methyl-pteridin (8-Halomethylpteridines) Werner Loop, Rudolf Tschesche -/- Anmelder: Schering AG Patent: DE 828545 (C) 1952-01-17 |
25 |
Verfahren zur Darstellung von 9-Oxy-pteroinsäure und 9-Oxy-pteroinsäurederivaten, insbesondere 9-Oxy-pteroyl-glutaminsäure (Oxyfolinsäure) Rudolf Tschesche, Friedhelm Korte, Carl-Heinz Köhncke -/- Anmelder: Schering AG Patent: DE 836651 (C) 1952-04-15 |
24 |
Verfahren zur Darstellung von 9-Oxy-pteroinsäure und 9-Oxy-pteroinsäurederivaten, insbesondere 9-Oxy-pteroyl-glutaminsäure (Oxyfolinsäure) (7-Hydroxypteroic acid and 7-hydroxyfolic acid) Rudolf Tschesche, Friedhelm Korte, Carl-Heinz Köhncke -/- Anmelder: Schering AG Patent: DE 836651 (C) 1952-04-15 |
23 |
Verfahren zur Herstellung von Schiff'schen Basen aus Sulfanilsäure-amiden der Pyrimidinreihe (Preparation of Schiff bases from sulfanilamides of the pyrimidine series) Rudolf Tschesche, Hermann Fox -/- Anmelder: Schering AG Patent: DE 847898 (C) 1952-08-28 |
22 |
Verfahren zur Herstellung neuer, in 8-Stellung substituierter 6,9-Dioxy-2-amino-pteridinderivate Rudolf Tschesche, Friedhelm Korte -/- Anmelder: Nordmark Werke GmbH Patent: DE 855712 (C) 1952-11-17 |
21 |
Verfahren zur Herstellung hydrierter Pteridinderivate (Hydrogenated pteridines) Rudolf Tschesche, Friedhelm Korte -/- Anmelder: Nordmark Werke GmbH Patent: DE 859315 (C) 1952-12-11 |
1949 | |
20 |
Sätt att framställa 2-aminopyrimidinföreningar och deras derival. (2-Aminopyrimidine compounds and their derivation) Rudolf Tschesche, Hermann Fox, S. Grünler, G. Blumenfeld Patent: SE 125183 (C) 1949-06-21 |
1945 | |
19 |
Sulphones of the aromatic series and a method of making the same Rudolf Tschesche -/- Anmelder: Schering Corp. Patent: US 2382924 (A) 1945-08-14 |
1944 | |
18 |
Substituted p,p'-diamino diphenyl sulphones and a process of making the same Rudolf Tschesche, Kurt Bohle -/- Anmelder: Schering Corp. Patent: US 2354784 (A) 1944-08-01 |
17 |
Process for isolating the lactationpromoting hormone Karl Junkmann, Rudolf Tschesche -/- Anmelder: Schering Corp. Patent: US 2364852 (A) 1944-12-12 |
1943 | |
16 |
Verfahren zur Herstellung wasserlöslicher 4,4'-Diaminodiphenylsulfonverbindungen (Water-soluble 4,4'-diaminodiphenyl sulfones) Rudolf Tschesche, Kurt Bohle -/- Anmelder: Schering AG Patent: DE 735560 (C) 1943-05-18 |
15 |
Verfahren zur Herstellung von p,p-Diaminodiphenylsulfon (p,p'-Diaminodiphenyl sulfone) Rudolf Tschesche, Kurt Bohle -/- Anmelder: Schering AG Patent: DE 740445 (C) 1943-10-21 |
14 |
Process for the manufacture of p,p'-diamino-diphenyl-sulphone and its monoamino derivatives Rudolf Tschesche, Kurt Bohle -/- Anmelder: Schering Corp. Patent: US 2331009 (A) 1943-10-05 |
1942 | |
13 |
Verfahren zur Trennung und Reinigung der Hormone des Hypolphysenhinterlappens (Isolation and purification of hormones from the posterior lobe of the hypophysis) Rudolf Tschesche, Kurt Bohle, Karl Junkmann -/- Anmelder: Schering AG Patent: DE 719970 (C) 1942-05-05 |
12 |
Verfahren zur Darstellung von substituierten p,p-Diaminodiphenylsulfonen (Substituted p,p'-diaminodiphenyl sulfone) Rudolf Tschesche -/- Anmelder: Schering AG Patent: DE 728467 (C) 1942-11-27 |
1941 | |
11 |
Verfahren zur Darstellung von substituierten p,p'-Diaminodiphenylsulfonen (Substituted p,p'-diaminodiphenyl sulfones) Rudolf Tschesche, Kurt Bohle -/- Anmelder: Schering AG Patent: DE 704017 (C) 1941-03-21 |
10 |
Verfahren zur Trennung und Reinigung der uterus- und blutdruckwirksamen Hormone des Hypophysenhinterlappens (Isolation and purification of the hormone of the uterus and the hormone affecting blood pressure) Rudolf Tschesche, Kurt Bohle, Karl Junkmann -/- Anmelder: Schering AG Patent: DE 712161 (C) 1941-10-14 |
1938 | |
9 |
Verfahren zur Herstellung pharmakologisch wirksamer, Ferroverbindungen enthaltender Zubereitungen Franz Seitz, Christian Bomskov -/- Anmelder: Chemische Fabrik Promonta GmbH Patent: DE 665778 (C) 1938-10-04 |
8 |
Verfahren zur Herstellung eines zimtartigen Gewürzpulvers (Spice composition) Erich Pohl, Hans Schmalfuß Patent: DE 668073 (C) 1938-11-25 |
1937 | |
7 |
Process for the treatment of the flesh of marine mammals Hans Schmalfuß, Hans Werner Patent: US 2077533 (A) 1937-04-20 |
1936 | |
6 |
Verfahren zur Verarbeitung von Walfleisch für den menschlichen Genuss (Improvements in or relating to the treatment of the tissue of marine animals) Hans Schmalfuß, Hans Werner Patent: DE 628999 (C) 1936-04-21; GB 445275 (A) 1936-04-01 |
5 |
Improvements in and relating to the treatment of the flesh and other tissue of marinemammals Hans Schmalfuß, Hans Werner Patent: GB 445462 (A) 1936-04-06 |
1935 | |
4 |
Verfahren zur Vertilgung nesterbauender Insekten (Destroying leaf-cutting ants and like nest-building insects) Meinhard Jacoby, Hans Schmalfuß Patent: DE 613274 (C) 1935-08-17 |
3 |
Improvements in and relating to edible extracts from the flesh of sea animals Hans Schmalfuß, Hans Werner Patent: GB 431143 (A) 1935-06-27 |
1934 | |
2 |
Foam separator for fermentation apparatus, plants and the like Ernst Jantzen, Hans Schmalfuß Patent: US 1967938 (A) 1934-07-24 |
1929 | |
1 |
Verfahren zur Veredelung des Tabakaromas Hans Schmalfuß, Annegrete Schaeffer Patent: DE 554545 (C) 1932-07-09 |