Department of Chemestry
Publications by Lars Redecke
Short biography
| 1975 | born in Hamburg |
| 2005 | Promotion with Christian Betzel in Hamburg |
| 2009-2016 | Group leader of the joint junior research group "Structural Infection Biology Using New Sources of Radiation (SIAS)" at the Laboratory for Structural Biology of Infection and Inflammation of the University of Lübeck and the University of Hamburg at the German Electron Synchrotron (DESY) |
| 2016- | University Professor (W2) at the University of Lübeck for "Structural Infection Biology with New Radiation Sources". |
Further Informatio
Publications
(only until the end of Hamburg time, until 1916)
.
| Search: Chemistry Dep. / all Hamburg | |
| 2016 | |
| 30 |
Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris Rossana García-Fernández, Patrick Ziegelmüller, Lidice González, Manuel Mansur, Yoan Machado, Lars Redecke , Ulrich Hahn , Christian Betzel , Maria de los Angeles Chávez Protein Expression and Purification 123, 42-50 (2016) |
| 29 |
Understanding Virus Mechanisms by Means of Native Mass Spectrometry Boris Krichel, Sven Falke, Johannes Heidemann, Julia Lockhauserbäumer, Rolf Hilgenfeld, Matthew Dunne, Rob Meijers, Lars Redecke , Charlotte Utrecht 64st ASMS Conference on Mass Spectrometry and Allied Topics, June 5-9, 2016, San Antonio, Texas, Program Book TP 699 (2016) |
2015 | |
| 28 |
In
vivo protein crystallization in combination with highly brilliant radiation sources offers novel opportunities for the structural analysis of post-translationally modified eukaryotic proteins Michael Duszenko, Lars Redecke , Celestin Nzanzu Mudogo, Benjamin Philip Sommer, Stefan Mogk, Dominik Oberthür , Christian Betzel Acta Crystallographica, Section F: Structural Biology Communications F71, 929-937 (2015) |
| 27 |
Three-dimensional structure of a Kunitz-type inhibitor in complex with an elastase-like enzyme Rossana García-Fernández, Markus Perbandt , Dirk Rehders , Patrick Ziegelmüller, Nicolas Piganeau, Ulrich Hahn , Christian Betzel , Maria de los Angeles Chávez, Lars Redecke Journal of Biological Chemistry 290, 14154-14165 (2015) |
| 26 |
Electronic damage in S atoms in a native protein crystal induced by an intense X-ray free-electron laser pulse Lorenzo Galli, S.-K. Son, Marco Klinge, Saša Bajt, Anton Barty, Richard Bean, Christian Betzel , Kenneth R. Beyerlein, Carl Caleman, R. Bruce Doak, Michael Duszenko, Holger Fleckenstein, C. Gati, B. Hunt, Richard A. Kirian , M. Liang, Max H. Nanao, Karol Nass, Dominik Oberthür , Lars Redecke , Robert L. Shoeman, Francesco Stellato, Chun Hong Yoon, Thomas A. White , Oleksandr Yefanov, J. Spence, Henry N. Chapman Structural Dynamics 2, 041703 (2015) |
| 25 |
Real-time investigation of dynamic protein crystallization in living cells Robert Schönherr, Marco Klinge, J. M. Rudolph, K. Fita, Dirk Rehders , F. Lübber, S. Schneegans, Irina V. Majoul, Michael Duszenko, Christian Betzel , A. Brandariz-Nuñez, J. Martinez-Costas, Rainer Duden, Lars Redecke Structural Dynamics 2, 041712 (2015) |
2014 | |
| 24 |
Neue Möglichkeiten für die Strukturbiologie. In vivo Proteinkristallisation und Freie-Elektronen-Laser (New possibilities for structural biology. In vivo protein crystallization and free electron lasers) Lars Redecke , Christian Betzel , Michael Duzenko GIT Labor-Fachzeitschrift 58 (2) 53-55 (2014) |
| 23 |
Serial crystallography on in vivo grown microcrystals using synchrotron radiation Cornelius Gati, Gleb Bourenkov, Marco Klinge, Dirk Rehders , Francesco Stellato, Dominik Oberthür , Oleksandr Yefanov, Benjamin P. Sommer, Stefan Mogk, Michael Duszenko, Christian Betzel , Thomas R. Schneider, Henry N. Chapman , Lars Redecke IUCrJ 1, 87-94 (2014) |
2013 | |
| 22 |
Impact of methionine oxidation as an initial event on the pathway of human prion protein conversion Mohammed Ismail Youssef Elmallah, Uwe Borgmeyer, Christian Betzel , Lars Redecke Prion 7, 404-411 (2013) |
| 21 |
Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser Lars Redecke , Karol Nass, Daniel P. DePonte, Thomas A. White , Dirk Rehders , Anton Barty, Francesco Stellato, Mengning Liang, Thomas R. M. Barends, Sébastien Boutet, Garth J. Williams, Marc Messerschmidt, M. Marvin Seibert, Andrew Aquila, David Arnlund, Saša Bajt, Torsten Barth, Michael J. Bogan, Carl Caleman, Tzu-Chiao Chao, R. Bruce Doak, Holger Fleckenstein, Matthias Frank, Raimund Fromme, Lorenzo Galli, Ingo Grotjohann, Mark S. Hunter, Linda C. Johansson, Stephan Kassemeyer, Gergely Katona, Richard A. Kirian , Rudolf Koopmann, Christopher Kupitz, Lukas Lomb, Andrew V. Martin, Stefan Mogk, Richard Neutze, Robert L. Shoeman, Jan Steinbrener, Nicusor Timneanu, Dingjie Wang, Uwe Weierstall, Nadia A. Zatsepin, John C. H. Spence, Petra Fromme, Ilme Schlichting, Michael Duszenko, Christian Betzel , Henry N. Chapman Science 339, 227-230 (2013) Reprint: Science Express. Published Online November 29 (2012) |
2012 | |
| 20 |
Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus Rossana García-Fernández, Tirso Pons, Arne Meyer, Markus Perbandt , Yamile González-González, Dayrom Gil, María A. Chávez, Christian Betzel , Lars Redecke Acta Crystallographica, Section F: Structural Biology and Crystallization Communications F68, 1289-1293 (2012) |
| 19 |
Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus Rossana García-Fernández, Tirso Pons, Arne Meyer, Markus Perbandt , Yamile González-González, Dayrom Gil, Maria de los Angeles Chávez, Christian Betzel , Lars Redecke Acta Crystallographica, Section F: Structural Biology and Crystallization Communications F68, 1289-1293 (2012) |
| 18 |
Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor Rossana García-Fernández, Tirso Pons, Markus Perbandt , Pedro A. Valiente, Ariel Talavera, Yamile González-González, Dirk Rehders , María A. Chávez, Christian Betzel , Lars Redecke Journal of Structural Biology 180, 271-279 (2012) |
| 17 |
In vivo protein crystallization opens new routes in structural biology Rudolf Koopmann, Karolina Cupelli, Lars Redecke , Karol Nass, Daniel P. DePonte, Thomas A. White , Francesco Stellato, Dirk Rehders , Mengning Liang, Jakob Andreasson, Andrew Aquila, Saša Bajt, Miriam Barthelmeß , Anton Barty, Michael J. Bogan, Christoph Bostedt, Sébastien Boutet, John D. Bozek, Carl Caleman, Nicola Coppola, Jan Davidsson, R. Bruce Doak, Tomas Ekeberg, Sascha W. Epp , Benjamin Erk, Holger Fleckenstein, Lutz Foucar, Heinz Graafsma, Lars Gumprecht, Janos Hajdu, Christina Y. Hampton, Andreas Hartmann, Robert Hartmann, Günter Hauser, Helmut Hirsemann, Peter Holl, Mark S. Hunter, Stephan Kassemeyer, Richard A. Kirian , Lukas Lomb, Filipe R. N. C. Maia, Nils Kimmel, Andrew V. Martin, Marc Messerschmidt, Christian Reich, Daniel Rolles, Benedikt Rudek, Artem Rudenko, Ilme Schlichting, Joachim Schulz, M. Marvin Seibert, Robert L. Shoeman, Raymond G. Sierra, Heike Soltau, Stephan Stern, Lothar Strüder, Nicusor Timneanu, Joachim Ullrich, Xiaoyu Wang, Georg Weidenspointner, Uwe Weierstall, Garth J. Williams, Cornelia B. Wunderer, Petra Fromme, John C. H. Spence, Thilo Stehle, Henry N. Chapman , Christian Betzel , Michael Duszenko Nature Methods 9, 259-262 (2012) |
| 16 |
High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography Sébastien Boutet, Lukas Lomb, Garth J. Williams, Thomas R. M. Barends, Andrew Aquila, R. Bruce Doak, Uwe Weierstall, Daniel P. DePonte, Jan Steinbrener, Robert L. Shoeman, Marc Messerschmidt, Anton Barty, Thomas A. White , Stephan Kassemeyer, Richard A. Kirian , M. Marvin Seibert, Paul A. Montanez, Chris Kenney, Ryan Herbst, Philip Hart, Jack Pines, Gunther Haller, Sol M. Gruner, Hugh T. Philipp, Mark W. Tate, Marianne Hromalik, Lucas J. Koerner, Niels van Bakel, John Morse, Wilfred Ghonsalves, David Arnlund, Michael J. Bogan, Carl Caleman, Raimund Fromme, Christina Y. Hampton, Mark S. Hunter, Linda C. Johansson, Gergely Katona, Christopher Kupitz, Mengning Liang, Andrew V. Martin, Karol Nass, Lars Redecke , Francesco Stellato, Nicusor Timneanu, Dingjie Wang, Nadia A. Zatsepin, Donald Schafer, James Defever, Richard Neutze, Petra Fromme, John C. H. Spence, Henry N. Chapman , Ilme Schlichting Science 337, 362-364 (2012) |
2010 | |
| 15 |
CHL1 is a selective organizer of the presynaptic machinery chaperoning the SNARE complex Aksana Andreyeva, Iryna Leshchyns'ka, Michael Knepper, Christian Betzel , Lars Redecke , Vladimir Sytnyk, Melitta Schachner PLoS One 5, e12018 (2010) |
| 14 |
Interactions of ginkgolides A and B with a recombinant human prion protein Dessislava Nikolova Georgieva, Lars Redecke , Martin von Bergen, Nicolay Genov, Christian Betzel Protein & Peptide Letters 17, 399-404 (2010) |
2009 | |
| 13 |
UV-light-induced conversion and aggregation of prion proteins Lars Redecke , Stephan Binder, Mohammed Ismail Youssef Elmallah, Rebecca Broadbent, Claudia Tilkorn, Benjamin Schulz, Patrick May, Arne Goos, Andreas Eich, Michael Rübhausen , Christian Betzel Free Radical Biology & Medicine 46, 1353-1361 (2009) |
| 12 |
Peptide NMHRYPNQ of the Cellular Prion Protein (PrPC) Inhibits Aggregation and Is a Potential Key for Understanding Prion-Prion Interactions Dirk Rehders , Birgit Claasen, Lars Redecke , Alexander Buschke, Caroline Reibe, Nico Jehmlich, Martin von Bergen, Christian Betzel , Bernd Meyer Journal of Molecular Biology 392, 198-207 (2009) |
2008 | |
| 11 |
Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus Jan-Hendrik Hehemann, Lars Redecke , Jayaseelan Murugaiyan, Martin von Bergen, Christian Betzel , Reinhard Saborowski Biochemical and Biophysical Research Communications 370, 566-571 (2008) |
2007 | |
| 10 |
Crystallization and preliminary x-ray diffraction studies of trypsin-like proteases from the gastric fluid of the marine crab Cancer pagurus Jan-Hendrik Hehemann, Lars Redecke , Markus Perbandt , Reinhard Saborowski, Christian Betzel Acta Crystallographica, Section F: Structural Biology and Crystallization Communications F63, 242-245 (2007) |
| 9 |
Cloning and characterization of dihydrofolate reductase from a facultative alkaliphilic and halotolerant bacillus strain Lars Redecke , Maria A. Brehm, Reinhard Bredehorst Extremophiles 11, 75-83 (2007) |
| 8 |
Structural characterization of β-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro Lars Redecke , Martin von Bergen, Joachim Clos, Petr V. Konarev, Dmitri I. Svergun, Ursula E. A. Fittschen , José A. C. Broekaert, Oliver T. Bruns, Dessislava Nikolova Georgieva, Eckhard Mandelkow, Nicolay Genov, Christian Betzel Journal of Structural Biology 157, 308-320 (2007) |
| 7 |
Release Factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies Gabriel Zoldak, Lars Redecke , Dmitri I. Svergun, Petr V. Konarev, C. Stefan Voertler, Holger Dobbek, Erik Sedlak, Mathias Sprinzl Nucleic Acids Research 35, 1343-1353 (2007) |
2006 | |
| 6 |
Interactions of recombinant prions with compounds of therapeutical significance Dessislava Nikolova Georgieva, Daniel Schwark, Martin von Bergen, Lars Redecke , Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 344, 463-470 (2006) |
| 5 |
Stabilisierungsmechanismen extremophiler Proteine am Beispiel bakterieller Dihydrofolatreduktasen Lars Redecke -/- Supervisor: Reinhard Bredehorst Dissertation, Hamburg (2006), ISBN 978-3-89703-666-6; 3-89703-666-5 , Publisher: Görich & Weiershäuser, Marburg |
| 4 |
Structural investigations of prion protein aggregation Lars Redecke , Marko Silvestric, Joachim Clos, Petr V. Konarev, Dmitri I. Svergun, Wolfram Meyer-Klaucke, Dessislava Nikolova Georgieva, Nicolay Genov, Christian Betzel Deutsche Tagung für Forschung mit Synchrotronstrahlung, Neutronen und Ionenstrahlen an Großgeräten 2006. SNI2006. Universität Hamburg, 04.-06. Oktober 2006. Programm und Abstracts Poster M-P206 (2006) |
2005 | |
| 3 |
Comparative Analysis of the Human and Chicken Prion Protein Copper Binding Regions at pH 6.5 Lars Redecke , Wolfram Meyer-Klaucke, Mirjam Koker, Joachim Clos, Dessislava Nikolova Georgieva, Nicolay Genov, Hartmut Echner, Hubert Kalbacher, Markus Perbandt , Reinhard Bredehorst, Wolfgang Voelter, Christian Betzel Journal of Biological Chemistry 280, 13987-13992 (2005) |
2004 | |
| 2 |
Oligomerization of the proteolytic products is an intrinsic property of prion proteins Dessislava Nikolova Georgieva, Mirjam Koker, Lars Redecke , Markus Perbandt , Joachim Clos, Reinhard Bredehorst, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 323, 1278-1286 (2004) |
| 1 |
Synthetic human prion protein octapeptide repeat binds to the proteinase K active site Dessislava Nikolova Georgieva, Wojciech Rypniewski, Hartmut Echner, Markus Perbandt , Mirjam Koker, Joachim Clos, Lars Redecke , Reinhard Bredehorst, Wolfgang Voelter, Nicolay Genov, Christian Betzel Biochemical and Biophysical Research Communications 325, 1406-1411 (2004) |