Department of Chemestry
Publications by Boris Illarionov
| Search: Chemistry Dep. / all Hamburg | |
| 2025 | |
| 136 |
Expanding the Chemical Space of Reverse Fosmidomycin Analogs Talea Knak, Sana Takada, Boris A. Illarionov , Violetta Krisilia, Lais Pessanha de Carvalho, Beate Lungerich, Yasumitsu Sakamoto, Stefan Höfmann, Adelbert Bacher , Rainer Kalscheuer, Jana Held, Markus Fischer , Nobutada Tanaka, Thomas Kurz ACS Medicinal Chemistry Letters 16, 136-143 (2025) |
| 135 |
Transient 19F photo-CIDNP: A practical tool to distinguish intermediate radical species and determine isotropic hyperfine coupling constants of 19F nuclei Anton Schmidt, Audrey Ayekoi, Boris A. Illarionov , Markus Fischer , Adelbert Bacher , Stefan Weber Journal of Chemical Physics 162, 054204 (2025) (Special Collection: Dynamic Exciton for Materials, Biology and Energy Conversion) |
2024 | |
| 134 |
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation YongLe He, Jinnette Tolentino Collado, James Iuliano, Helena Woroniecka, Christopher Hall, Agnieszka Gil, Sergey Laptenok, Gregory Greetham, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Jarrod French, Andras Lukacs, Stephen Meech, Peter J. Tonge ACS Chemical Biology 19, 696-706 (2024) |
| 133 |
Reverse N-Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase (DXR) Mona A. Abdullaziz, Sana Takada, Boris A. Illarionov , Lais Pessanha de Carvalho, Yasumitsu Sakamoto, Stefan Höfmann, Talea Knak, Anna-Lene Kiffe-Delf, Flaminia Mazzone, Klaus Pfeffer, Rainer Kalscheuer, Adelbert Bacher , Jana Held, Markus Fischer , Nobutada Tanaka, Thomas Kurz ACS Infectious Disease 10, 1739-1752 (2024) |
| 132 |
Targeting the Plasmodium falciparum IspE enzyme Eleonora Diamanti, Annina M. Steinbach, Lais P. de Carvalho, Henni-Karoliina Ropponen, Antoine Lacour, Rawia Hamid, Sidra Eisa, Patricia Bravo, Spyridon Bousis, Boris A. Illarionov , Markus Fischer , Mostafa M. Hamed, Nina C. Bach, Matthias Rottmann, Jana Held, Matthias Witschel, Stephan A. Sieber, Anna K. H. Hirsch ACS Omega 9, 44465-44473 (2024) |
| 131 |
Food Authentication: The Detection of Arbutus unedo and Olea europaea Leaves as an Admixture of Oregano Using LAMP- and Duplex LAMP-Based Test Systems with Lateral-Flow Assays Nathalie Holz, Nils Wax, Boris A. Illarionov , Margarita Iskhakova, Markus Fischer Agriculture 14, 597 (15 pp) (2024) |
| 130 |
Systematic analysis of the effect of genomic knock-out of non-essential promiscuous HAD-like phosphatases YcsE, YitU and YwtE on flavin and adenylate content in Bacillus subtilis Alexandra Scharf, Farshad La-Rostami, Boris A. Illarionov , Vivien Nemes, Anna M. Feldmann, Lars S. Höft, Henri Lösel, Adelbert Bacher , Markus Fischer ChemBioChem 25, e202400165 (14 pp) (2024) |
| 129 |
Targeting Plasmodium falciparum IspD in the Methyl-D-Erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on target with low micromolar whole-cell activity Daan Willocx, Lorenzo Bizzarri, Alaa Alhayek, Patricia Bravo, Boris A. Illarionov , Katharina Rox, Jonas Lohse, Markus Fischer , Andreas M. Kany, Hannes Hahne, Matthias Rottmann, Matthias Witschel, Mostafa M. Hamed, Eleonora Diamanti, Anna K. H. Hirsch ChemRxiv 2024-15kb1, 17 pp (2024) |
| 128 |
Shining a Spotlight on Methyl Groups: Photochemically Induced Dynamic Nuclear Polarization Spectroscopy of 5-Deazariboflavin and its Nor Analogs Sabrina Panter, Audrey Ayekoi, Jannis Tesche, Jing Chen, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Stefan Weber International Journal of Molecular Sciences 25, 848 (15 pp) (2024) |
| 127 |
Targeting Plasmodium falciparum IspD in the Methyl-D-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity Daan Willocx, Lorenzo Bizzarri, Alaa Alhayek, Deepika Kannan, Patricia Bravo, Boris A. Illarionov , Katharina Rox, Jonas Lohse, Markus Fischer , Andreas M. Kany, Hannes Hahne, Matthias Rottmann, Matthias Witschel, Audrey Odom John, Mostafa M. Hamed, Eleonora Diamanti, Anna K. H. Hirsch Journal of Medicinal Chemistry 67, 17070-17086 (2024) |
| 126 |
Adaptive Laboratory Evolution of Flavin Functionality Identifies Dihydrolipoyl Dehydrogenase as One of the Critical Points for the Activity of 7,8-Didemethyl-Riboflavin as a Surrogate for Riboflavin in Escherichia coli Farshad La-Rostami, Alexandra Scharf, Chenyang Albert, Nils Wax, Marina Creydt , Boris A. Illarionov , Adelbert Bacher , Stefan Weber, Markus Fischer Molecules 29, 5891 (14 pp) (2024) |
| 125 |
Preparation and Immunochemical Characterization of a Water-Soluble Gluten Peptide Fraction for Improving Diagnosis of Celiac Disease Niklas Meyer, Boris A. Illarionov , Markus Fischer , Herbert Wieser Nutrients 16, 742 (15 pp) (2024) |
| 124 |
Insights Into the Photoswitch Based on 5-DeazaFMN and LOV2 from Avena sativa: A Combined Absorption and NMR Spectroscopy Study Sabrina Panter, Jakob Wörner, Jing Chen, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Stefan Weber Physical Chemistry Chemical Physics 26, 28884-28893 (2024) |
2023 | |
| 123 |
Expanding Reaction Horizons: Evidence of the 5-Deazaflavin Radical Through Photo-Chemically Induced Dynamic Nuclear Polarization (Erweiterung des Reaktionsspektrums: Nachweis des 5-Deazaflavin-Radikals durch photochemisch induzierte dynamische Kernpolarisation) Jakob Wörner, Sabrina Panter, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Stefan Weber Angewandte Chemie, International Edition 61, e202309334 (6 pp) (2023) |
| 122 |
Exploring the translational gap of a novel class of Escherichia coli IspE inhibitors Henni-Karoliina Ropponen, Eleonora Diamanti, Sandra Johannsen, Boris A. Illarionov , Rawia Hamid, Miriam Jaki, Peter Sass, Markus Fischer , Jörg Haupenthal, Anna Katharina Herta Hirsch ChemMedChem 8, e202300346 (11 pp) (2023) |
| 121 |
Point-of-care suitable identification of the adulterants Carthamus tinctorius and Curcuma longa in Crocus sativus based on loop-mediated isothermal amplification (LAMP) and lateral-flow-assay (LFA) Nathalie Holz, Boris A. Illarionov , Nils Wax, Celina Schmidt, Markus Fischer Food Control 148, 109637 (2023) |
2022 | |
| 120 |
Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening Di Zhu, Sandra Johannsen, Tiziana Masini, Céline Simonin, Jörg Haupenthal, Boris A. Illarionov , Anastasia Andreas, Mahendra Awale, Robin M. Gierse, Tridia van der Laan, Ramon van der Vlag, Rita Nasti, Mael Poizat, Eric Buhler, Norbert Reiling, Rolf Müller, Markus Fischer , Jean-Louis Reymond, Anna K. H. Hirsch Chemical Science 13, 10686-10698 (2022) |
| 119 |
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class Eleonora Diamanti, Mostafa M. Hamed, Antoine Lacour, Patricia Bravo, Boris A. Illarionov , Markus Fischer , Matthias Rottmann, Matthias Witschel, Anna K. H. Hirsch ChemMedChem 17, e202100679 (4 pp) (2022) |
| 118 |
Completing the Picture: Determination of 13C Hyperfine Coupling Constants of Flavin Semiquinone Radicals by Photochemically Induced Dynamic Nuclear Polarization Spectroscopy Nils Pompe, Boris A. Illarionov , Markus Fischer , Adelbert Bacher , Stefan Weber Journal of Physical Chemistry Letters 13, 5160-5167 (2022) |
2021 | |
| 117 |
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity Henni-Karoliina Ropponen, Chantal D. Bader, Eleonora Diamanti, Boris A. Illarionov , Matthias Rottmann, Markus Fischer , Matthias Witschel, Rolf Müller, Anna K. H. Hirsch ChemMedChem 16, 2089-2093 (2021) |
| 116 |
Genetic Profiling - Bestimmung der biologischen Identität von Apfelrohware und Apfelprodukten Anne Haferkorn, Boris A. Illarionov , Markus Fischer Lebensmittelchemie 75 (S2) S058-S058 (2021) |
| 115 |
Assessment of the rules related to gaining activity against Gram-negative bacteria Henni-Karoliina Ropponen, Eleonora Diamanti, Alexandra Siemens, Boris A. Illarionov , Jörg Haupenthal, Markus Fischer , Matthias Rottmann, Matthias Witschel, Anna K. H. Hirsch RSC Medicinal Chemistry 12, 593-601 (2021) |
| 114 |
Selective 13C labelling reveals the electronic structure of flavocoenzyme radicals Erik Schleicher, Stephan Rein, Boris A. Illarionov , Ariane Lehmann, Tarek Al Said, Sylwia Kacprzak, Robert Bittl, Adelbert Bacher , Markus Fischer , Stefan Weber Scientific Reports 11, 18234 (9 pp) (2021) |
2020 | |
| 113 |
Coupled Methyl Group Rotation in FMN Radicals Revealed by Selective Deuterium Labeling Richard Brosi, Boris A. Illarionov , Lorenz Heidinger, Ryu-Ryun Kim, Markus Fischer , Stefan Weber, Adelbert Bacher , Robert Bittl, Erik Schleicher Journal of Physical Chemistry B 124, 1678-1690 (2020) |
| 112 |
Excited State Vibrations of Isotopically Labeled FMN Free and Bound to a Light-Oxygen-Voltage (LOV) Protein James N. Iuliano, Christopher R. Hall, Dale Green, Garth A. Jones, Andras Lukacs, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Jarrod B. French, Peter J. Tonge, Stephen R. Meech Journal of Physical Chemistry B 124, 7152-7165 (2020) |
| 111 |
The crystal structure of mycobacterial epoxide hydrolase A Eike C. Schulz, Sara R. Henderson, Boris A. Illarionov , Thomas Crosskey, Stacey M. Southall, Boris Krichel, Charlotte Uetrecht, Markus Fischer , Matthias Wilmanns Scientific Reports 10, 16539 (14 pp) (2020) |
2019 | |
| 110 |
Structure of GTP cyclohydrolase I from Listeria monocytogenes, a potential anti-infective drug target Sonja Schüssler, Ilka Haase, Markus Perbandt , Boris A. Illarionov , Alexandra Siemens, Klaus Richter, Adelbert Bacher , Markus Fischer , Tobias Gräwert Acta Crystallographica, Section F: Structural Biology Communications 75, 586-592 (2019) |
| 109 |
Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity Claudia Lienau, Tobias Gräwert , Leandro A. Alves Avelar, Boris A. Illarionov , Jana Held, Tanja C. Knaab, Beate Lungerich, Lasse van Geelen, Dieter Meier, Stefanie Geissler, Holger Cynis, Ulrich Riederer, Mirko Buchholz, Rainer Kalscheuer, Adelbert Bacher , Benjamin Mordmüller, Markus Fischer , Thomas Kurz European Journal of Medicinal Chemistry 181, 111555 (2019) |
| 108 |
Inhibitors of the Bifunctional 2-C-Methyl-D-erythritol 4-Phosphate Cytidylyl Transferase/2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate Synthase (IspDF) of Helicobacter pylori Annika Honold, Clara Lettl, Franziska Schindele, Boris A. Illarionov , Rainer Haas, Matthias Witschel, Adelbert Bacher , Markus Fischer Helvetica Chimica Acta 102, e1800228 (2019) |
| 107 |
Methyl groups matter: Photo-CIDNP characterizations of the semiquinone radicals of FMN and demethylated FMN analogs Nils Pompe, Jing Chen, Boris A. Illarionov , Sabrina Panter, Markus Fischer , Adelbert Bacher , Stefan Weber Journal of Chemical Physics 151, 235103 (12 pp) (2019) |
2018 | |
| 106 |
Variation in LOV Photoreceptor Activation Dynamics Probed by Time Resolved Infrared Spectroscopy James N. Iuliano, Agnieszka A. Gil, Sergey P. Laptenok, Christopher R. Hall, Jinnette Tolentino Collado, Andras Lukacs, Safaa A. Hag Ahmed, Jenna Abyad, Taraneh Daryaee, Gregory M. Greetham, Igor V. Sazanovich, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Michael Towrie, Jarrod B. French, Stephen R. Meech, Peter J. Tonge Biochemistry 57, 620-630 (2018) |
| 105 |
Phage display on anti-infective target DXS led to an acceptor-substrate competitive peptidic inhibitor Alessio Marcozzi, Tiziana Masini, Di Zhu, Diego Pesce, Boris A. Illarionov , Markus Fischer , Andreas Herrmann, Anna Katharina Herta Hirsch ChemBioChem 19, 58-65 (2018) |
| 104 |
Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor Katharina Root, Konstantin Barylyuk, Anatol Schwab, Jonas Thelemann, Boris A. Illarionov , Julie G. Geist, Tobias Gräwert , Adelbert Bacher , Markus Fischer , François Diederich, Renato Zenobi Chemical Science 9, 5976-5986 (2018) |
| 103 |
Long-Lived Hydrated FMN Radicals. EPR Characterization and Implications for Catalytic Variability in Flavoproteins Arpad Rostas, Christopher Einholz, Boris A. Illarionov , Lorenz Heidinger, Tarek Al Said, Anna Bauss, Markus Fischer , Adelbert Bacher , Stefan Weber, Erik Schleicher Journal of the American Chemical Society 140, 16521-16527 (2018) |
2017 | |
| 102 |
Mechanism
of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands Anatol Schwab, Boris A. Illarionov , Annika Frank, Andrea Kunfermann, Michael Seet, Adelbert Bacher , Matthias C. Witschel, Markus Fischer , Michael Groll, François Diederich ACS Chemical Biology 12, 2132-2138 (2017) |
| 101 |
Femtosecond to Millisecond Dynamics of Light Induced Allostery in the Avena sativa LOV Domain Agnieszka A. Gil, Sergey P. Laptenok, Jarrod B. French, James N. Iuliano, Andras Lukacs, Christopher R. Hall, Igor V. Sazanovich, Gregory M. Greetham, Adelbert Bacher , Boris A. Illarionov , Markus Fischer , Peter J. Tonge, Stephen R. Meech Journal of Physical Chemistry B 107, 1010-1019 (2017) |
2015 | |
| 100 |
Catalysis of an essential step in vitamin B2 biosynthesis by a consortium of broad spectrum hydrolases Sonja Sarge, Ilka Haase, Boris A. Illarionov , Dietmar Laudert, Hans-Peter Hohmann, Adelbert Bacher , Markus Fischer ChemBioChem 16, 2466-2469 (2015) Cover Picture: ChemBioChem 16, 2405-2405 (2015) |
| 99 |
Aryl Bis-Sulfonamide Inhibitors of IspF from Arabidopsis thaliana and Plasmodium falciparum Jonas Thelemann, Boris A. Illarionov , Konstantin Barylyuk, Julie G. Geist, Johannes Kirchmair , Petra Schneider, Lucile Anthore, Katharina Root, Nils Trapp, Adelbert Bacher , Matthias C. Witschel, Renato Zenobi, Markus Fischer , Gisbert Schneider, François Diederich ChemMedChem 10, 2090-2098 (2015) |
| 98 |
8-Substituted, syn-Configured Adenosine Derivatives as Potential Inhibitors of the Enzyme IspE from the Non-Mevalonate Pathway of Isoprenoid Biosynthesis Michael Harder, Elisabeth Schäfer, Tobias Kümin, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , François Diederich, Bruno Bernet European Journal of Organic Chemistry 7276-7286 (2015) Erratum: European Journal of Organic Chemistry Early 402-402 (2016) |
| 97 |
Prodrugs of reverse fosmidomycin analogs Karin Brücher, Tobias Gräwert , Sarah Konzuch, Jana Held, Claudia Lienau, Christoph Timon Behrendt, Boris A. Illarionov , Louis Maes, Adelbert Bacher , Sergio Wittlin, Benjamin Mordmüller, Markus Fischer , Thomas Kurz Journal of Medicinal Chemistry 58, 2025-2035 (2015) |
| 96 |
Preparation of flavocoenzyme isotopologues by biotransformation of purines Boris A. Illarionov , Feng Zhu, Wolfgang Eisenreich, Adelbert Bacher , Stefan Weber, Markus Fischer Journal of Organic Chemistry 80, 2539-2544 (2015) |
| 95 |
Strategy for Enhancement of 13C-Photo-CIDNP NMR Spectra by Exploiting Fractional 13C-Labeling of Tryptophan Wolfgang Eisenreich, Monika Joshi, Boris A. Illarionov , Sylwia Kacprzak, Michail Lukaschek, Gerd Kothe, Nediljko Budisa, Markus Fischer , Adelbert Bacher , Stefan Weber Journal of Physical Chemistry B 119, 13934-13943 (2015) |
| 94 |
Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS T. Masini, B. Lacy, L. Monjas, D. Hawksley, A. R. de Voogd, Boris A. Illarionov , A. Iqbal, F. J. Leeper, Markus Fischer , M. Kontoyianni, A. K. H. Hirsch Organic & Biomolecular Chemistry 13, 11263-11277 (2015) |
| 93 |
Inhibition of the Non-Mevalonate Isoprenoid Pathway by Reverse Hydroxamate Analogues of Fosmidomycin Claudia Lienau, Sarah Konzuch, Tobias Gräwert , Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Nobutada Tanaka, Thomas Kurz Procedia Chemistry 14, 108-116 (2015) |
2014 | |
| 92 |
Pseudilins: Halogenated, Allosteric Inhibitors of the Non-Mevalonate Pathway Enzyme IspD Andrea Kunfermann, Matthias C. Witschel, Boris A. Illarionov , René Martin, Matthias Rottmann, H. Wolfgang Höffken, Michael Seet, Wolfgang Eisenreich, Hans-Joachim Knölker, Markus Fischer , Adelbert Bacher , Michael Groll, François Diederich Angewandte Chemie, International Edition 53, 2235-2239 (2014) |
| 91 |
Deorphaning Pyrrolopyrazines as Potent Multi-Target Antimalarial Agents Daniel Reker, Michael Seet, Max Pillong, Christian P. Koch, Petra Schneider, Matthias C. Witschel, Matthias Rottmann, Céline Freymond, Reto Brun, Bernd Schweizer, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , François Diederich, Gisbert Schneider Angewandte Chemie, International Edition 53, 7079-7084 (2014) |
| 90 |
De novo fragment-based design of inhibitors of DXS guided by spin-diffusion-based NMR spectroscopy Tiziana Masini, Jens Pilger, Blijke S. Kroezen, Boris A. Illarionov , Philip Lottmann, Markus Fischer , Christian Griesinger, Anna K. H. Hirsch Chemical Science 5, 3543-3551 (2014) |
| 89 |
Binding modes of reverse fosmidomycin analogs towards the antimalarial target IspC Sarah Konzuch, Tomonobu Umeda, Jana Held, Saskia Hähn, Karin Brücher, Claudia Lienau, Christoph Timon Behrendt, Tobias Gräwert , Adelbert Bacher , Boris A. Illarionov , Markus Fischer , Benjamin Mordmüller, Nobutada Tanaka, Thomas Kurz Journal of Medicinal Chemistry 57, 8827-8838 (2014) |
| 88 |
Detecting a New Source for Photochemically Induced Dynamic Nuclear Polarization in the LOV2 Domain of Phototropin by Magnetic-Field Dependent 13C-NMR Spectroscopy Gerd Kothe, Michail Lukaschek, Gerhard Link, Sylwia Kacprzak, Boris A. Illarionov , Markus Fischer , Wolfgang Eisenreich, Adelbert Bacher , Stefan Weber Journal of Physical Chemistry B 118, 11622-11632 (2014) |
| 87 |
One Protein, Two Chromophores. Comparative Spectroscopic Characterization of 6,7-dimethyl-8-Ribityllumazine and Riboflavin Bound to Lumazine Protein Bernd Paulus, Boris A. Illarionov , Daniel Nohr, Guillaume Roellinger, Sylwia Kacprzak, Markus Fischer , Stefan Weber, Adelbert Bacher , Erik Schleicher Journal of Physical Chemistry B 118, 13092-13105 (2014) |
| 86 |
Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter Baumannii Richard James Brust, Allison Laura Haigney, Andras Lukacs, Agnieszka Gil, Shahrier Hossain, Kiri Addison, Cheng-Tsung Lai, Michael Towrie, Gregory M. Greetham, Ian P. Clark, Boris A. Illarionov , Adelbert Bacher , Ryu-Ryun Kim, Markus Fischer , Carlos Simmerling, Stephen Roy Meech, Peter J. Tonge Journal of Physical Chemistry Letters 5, 220-224 (2014) |
| 85 |
Bis-sulfonamide inhibitors of 2-methylerythritol 2, 4-cyclodiphosphate synthase (IspF) from Arabidopsis thaliana and Plasmodium falciparum Jonas Thelemann, Julie G. Geist, Konstantin Barylyuk, Boris A. Illarionov , Markus Fischer , Tobias Gräwert , Adelbert Bacher , Renato Zenobi, François Diederich Abstracts of Papers, 248th ACS National Meeting & Exposition, San Francisco, CA, United States, August 10-14, 2014, MEDI-385 (2014) |
| 84 |
Recent Advances in Riboflavin Biosynthesis Ilka Haase, Tobias Gräwert , Boris A. Illarionov , Adelbert Bacher , Markus Fischer -/- Editors: Stefan Weber, Erik Schleicher Methods in Molecular Biology 1146 (Flavins and Flavoproteins) 15-40 (2014) |
| 83 |
A Roadmap to the Isotopolog Space of Flavocoenzymes Adelbert Bacher , Boris A. Illarionov , Wolfgang Eisenreich, Markus Fischer -/- Editors: Stefan Weber, Erik Schleicher Methods in Molecular Biology 1146 (Flavins and Flavoproteins) 65-78 (2014) |
2013 | |
| 82 |
Enzymes from the Haloacid Dehalogenase (HAD) Superfamily Catalyse the Elusive Dephosphorylation Step of Riboflavin Biosynthesis Ilka Haase, Sonja Sarge, Boris A. Illarionov , Dietmar Laudert, Hans-Peter Hohmann, Adelbert Bacher , Markus Fischer ChemBioChem 14, 2272-2275 (2013) |
| 81 |
5-Substituted (1-Thiolan-2-yl)cytosines as Inhibitors of A. aeolicus and E. coli IspE Kinases: Very Different Affinities to Similar Substrate-Binding Sites Andri P. Schütz, Sebastian Locher, Bruno Bernet, Boris A. Illarionov , Markus Fischer , Adelbert Bacher , François Diederich European Journal of Organic Chemistry 880-887 (2013) |
| 80 |
Imidazole- and Benzimidazole-Based Inhibitors of the Kinase IspE: Targeting the Substrate-Binding Site and the Triphosphate-Binding Loop of the ATP Site Paolo Mombelli, Camille Le Chapelain, Noah Munzinger, Evelyne Joliat, Boris A. Illarionov , W. Bernd Schweizer, Anna K. H. Hirsch, Markus Fischer , Adelbert Bacher , François Diederich European Journal of Organic Chemistry 1068-1079 (2013) |
| 79 |
IspC as target for antiinfective drug discovery: Synthesis, enantiomeric separation and structural biology of fosmidomycin thia-isosters Andrea Kunfermann, Claudia Lienau, Boris A. Illarionov , Jana Held, Tobias Gräwert , Christoph Timon Behrendt, Philipp Werner, Saskia Hähn, Wolfgang Eisenreich, Ulrich Riederer, Benjamin Mordmüller, Adelbert Bacher , Markus Fischer , Michael Groll, Thomas Kurz Journal of Medicinal Chemistry 56, 8151-8162 (2013) |
2012 | |
| 78 |
Exploring the Ribose Sub-Pocket of the Substrate-Binding Site in Escherichia coli IspE: Structure-Based Design, Synthesis, and Biological Evaluation of Cytosines and Cytosine Analogues Andri P. Schütz, Sho Osawa, Jennifer Mathis, Anna K. H. Hirsch, Bruno Bernet, Boris A. Illarionov , Markus Fischer , Adelbert Bacher , François Diederich European Journal of Organic Chemistry 3278-3287 (2012) |
| 77 |
Arabidopsis RIBA Proteins: Two out of Three Isoforms Have Lost Their Bifunctional Activity in Riboflavin Biosynthesis Hanna-Maija Hiltunen, Boris A. Illarionov , Boris Hedtke, Markus Fischer , Bernhard Grimm International Journal of Molecular Sciences 13, 14086-14105 (2012) |
| 76 |
α-Substituted β-oxa Isosteres of Fosmidomycin: Synthesis and biological evaluation Karin Brücher, Boris A. Illarionov , Jana Held, Serena Tschan, Andrea Kunfermann, Miriam K. Pein, Adelbert Bacher , Tobias Gräwert , Louis Maes, Benjamin Mordmüller, Markus Fischer , Thomas Kurz Journal of Medicinal Chemistry 55, 6566-6575 (2012) |
| 75 |
O-Nucleoside, S-Nucleoside, and N-Nucleoside Probes of Lumazine Synthase and Riboflavin Synthase Arindam Talukdar, Yujie Zhao, Wei Lv, Adelbert Bacher , Boris A. Illarionov , Markus Fischer , Mark Cushman Journal of Organic Chemistry 77, 6239-6261 (2012) |
| 74 |
Vibrational Assignment of the Ultrafast Infrared Spectrum of the Photoactivatable Flavoprotein AppA Allison Laura Haigney, Andras Lukacs, Richard James Brust, Rui-Kun Zhao, Michael Towrie, Gregory M. Greetham, Ian P. Clark, Boris A. Illarionov , Adelbert Bacher , Ryu-Ryun Kim, Markus Fischer , Stephen Roy Meech, Peter J. Tonge Journal of Physical Chemistry B 116, 10722-10729 (2012) |
| 73 |
Lead discovery and optimization for IspD Michael Seet, Matthias C. Witschel, Wolfgang Hoffken, Liliana Parra, Thomas Mietzner, Frank Thater, Ricarda Niggeweg, Franz Röhl, Boris A. Illarionov , Felix Rohdich, Johannes Kaiser, Markus Fischer , Adelbert Bacher , François Diederich Abstracts of Papers, 244th ACS National Meeting & Exposition, Philadelphia, PA, United States, August 19-23, 2012, MEDI-132 (2012) |
2011 | |
| 72 |
Inhibitors of the Herbicidal Target IspD: Allosteric Site Binding Matthias C. Witschel, H. Wolfgang Höffken, Michael Seet, Liliana Parra, Thomas Mietzner, Frank Thater, Ricarda Niggeweg, Franz Röhl, Boris A. Illarionov , Felix Rohdich, Johannes Kaiser, Markus Fischer , Adelbert Bacher , François Diederich Angewandte Chemie, International Edition 50, 7931-7935 (2011) |
| 71 |
Ultrafast Infrared Spectroscopy of an Isotope-Labeled Photoactivatable Flavoprotein Allison Haigney, Andras Lukacs, Rui-Kun Zhao, Allison L. Stelling, Richard Brust, Ryu-Ryun Kim, Minako Kondo, Ian Clark, Michael Towrie, Gregory M. Greetham, Boris A. Illarionov , Adelbert Bacher , Werner Römisch-Margl, Markus Fischer , Stephen Roy Meech, Peter J. Tonge Biochemistry 50, 1321-1328 (2011) |
| 70 |
Reverse Fosmidomycin Derivatives against the Antimalarial Drug Target IspC (Dxr) Christoph Timon Behrendt, Andrea Kunfermann, Victoria A. Illarionova, An Matheeussen, Miriam K. Pein, Tobias Gräwert , Johannes Kaiser, Adelbert Bacher , Wolfgang Eisenreich, Boris A. Illarionov , Markus Fischer , Louis Maes, Michael Groll, Thomas Kurz Journal of Medicinal Chemistry 54, 6796-6802 (2011) |
| 69 |
Vibrational Spectra of the Ground and the Singlet Excited ππ* State of 6,7-Dimethyl-8-ribityllumazine Wolfgang J. Schreier, Igor Pugliesi, Florian O. Koller, Tobias E. Schrader, Wolfgang Zinth, Markus Braun, Sylwia Kacprzak, Stefan Weber, Werner Römisch-Margl, Adelbert Bacher , Boris A. Illarionov , Markus Fischer Journal of Physical Chemistry B 115, 3689-3697 (2011) |
2010 | |
| 68 |
Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracis Ekaterina Morgunova, Boris A. Illarionov , Sabine Saller, Aleksander Popov, Thota Sambaiah, Adelbert Bacher , Mark Cushman, Markus Fischer , Rudolf Ladenstein Acta Crystallographica, Section D: Biological Crystallography D66, 1001-1011 (2010) |
| 67 |
Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase Arindam Talukdar, Ekaterina Morgunova, Jianxin Duan, Winfried Meining, Nicolas Foloppe, Lennart Nilsson, Adelbert Bacher , Boris A. Illarionov , Markus Fischer , Rudolf Ladenstein, Mark Cushman Bioorganic & Medicinal Chemistry 18, 3518-3534 (2010) |
| 66 |
Thiazolopyrimidine Inhibitors of 2-Methylerythritol 2,4-Cyclodiphosphate Synthase (IspF) from Mycobacterium tuberculosis and Plasmodium falciparum Julie G. Geist, Susan Lauw, Victoria A. Illarionova, Boris A. Illarionov , Markus Fischer , Tobias Gräwert , Felix Rohdich, Wolfgang Eisenreich, Johannes Kaiser, Michael Groll, Christian Scheurer, Sergio Wittlin, Jose L. Alonso-Gomez, W. Bernd Schweizer, Adelbert Bacher , François Diederich ChemMedChem 5, 1092-1101 (2010) |
| 65 |
Mechanistic Insights on Riboflavin Synthase Inspired by Selective Binding of the 6,7-Dimethyl-8-ribityllumazine Exomethylene Anion Ryu-Ryun Kim, Boris A. Illarionov , Monika Joshi, Mark Cushman, Chan Yong Lee, Wolfgang Eisenreich, Markus Fischer , Adelbert Bacher Journal of the American Chemical Society 132, 2983-2990 (2010) |
| 64 |
Hindered Rotation of a Cofactor Methyl Group as a Probe for Protein-Cofactor Interaction Richard Brosi, Boris A. Illarionov , Tilo Mathes, Markus Fischer , Monika Joshi, Adelbert Bacher , Peter Hegemann, Robert Bittl, Stefan Weber, Erik Schleicher Journal of the American Chemical Society 132, 8935-8944 (2010) |
2009 | |
| 63 |
Discovery and Development of a Small Molecule Library with Lumazine Synthase Inhibitory Activity Arindam Talukdar, Meghan Breen, Adelbert Bacher , Boris A. Illarionov , Markus Fischer , Gunda I. Georg, Qi-Zhuang Ye, Mark Cushman Journal of Organic Chemistry 74, 5123-5134 (2009) |
| 62 |
Discovery and Development of the Covalent Hydrates of Trifluoromethylated Pyrazoles as Riboflavin Synthase Inhibitors with Antibiotic Activity Against Mycobacterium tuberculosis Yujie Zhao, Adelbert Bacher , Boris A. Illarionov , Markus Fischer , Gunda I. Georg, Qi-Zhuang Ye, Phillip E. Fanwick, Scott G. Franzblau, Baojie Wan, Mark Cushman Journal of Organic Chemistry 74, 5297-5303 (2009) |
2008 | |
| 61 |
Structure of Lumazine Protein, an Optical Transponder of Luminescent Bacteria Lorenz Chatwell, Victoria A. Illarionova, Boris A. Illarionov , Wolfgang Eisenreich, Robert Huber, Arne Skerra, Adelbert Bacher , Markus Fischer Journal of Molecular Biology 382, 44-55 (2008) |
| 60 |
A New Series of N-[2,4-Dioxo-6-D-ribitylamino-1,2,3,4-tetrahydropyrimidin-5-yl]oxalamic Acid Derivatives as Inhibitors of Lumazine Synthase and Riboflavin Synthase: Design, Synthesis, Biochemical Evaluation, Crystallography, and Mechanistic Implications Yanlei Zhang, Boris A. Illarionov , Ekaterina Morgunova, Guangyi Jin, Adelbert Bacher , Markus Fischer , Rudolf Ladenstein, Mark Cushman Journal of Organic Chemistry 73, 2715-2724 (2008) |
2007 | |
| 59 |
A high-throughput screening platform for inhibitors of the riboflavin biosynthesis pathway Johannes Kaiser, Boris A. Illarionov , Felix Rohdich, Wolfgang Eisenreich, Sabine Saller, Jan van den Brulle, Mark Cushman, Adelbert Bacher , Markus Fischer Analytical Biochemistry 365, 52-61 (2007) |
| 58 |
Lumazine proteins from photobacteria: localization of the single ligand binding site to the N-terminal domain Boris A. Illarionov , Wolfgang Eisenreich, Martina Wirth, Chan Yong Lee, Young-Eun Woo, Adelbert Bacher , Markus Fischer Biological Chemistry 388, 1313-1323 (2007) |
| 57 |
13C isotopologue editing of FMN bound to phototropin domains Wolfgang Eisenreich, Monika Joshi, Boris A. Illarionov , Gerald Richter, Werner Römisch-Margl, Franz Müller, Adelbert Bacher , Markus Fischer FEBS Journal 274, 5876-5890 (2007) |
| 56 |
Ligand binding properties of the N-terminal domain of riboflavin synthase from Escherichia coli Chan Yong Lee, Boris A. Illarionov , Young-Eun Woo, Kristina Kemter, Ryu-Ryun Kim, Sabine Eberhardt, Mark Cushman, Wolfgang Eisenreich, Markus Fischer , Adelbert Bacher Journal of Biochemistry and Molecular Biology 40, 239-246 (2007) |
| 55 |
A Novel Lumazine Synthase Inhibitor Derived from Oxidation of 1,3,6,8-Tetrahydroxy-2,7-naphthyridine to a Tetraazaperylenehexaone Derivative Yanlei Zhang, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Gunda I. Georg, Qi-Zhuang Ye, David Vander Velde, Phillip E. Fanwick, Yunlong Song, Mark Cushman Journal of Organic Chemistry 72, 2769-2776 (2007) |
| 54 |
Synthesis and enzyme inhibitory activity of the S-nucleoside analogue of the tibitylaminopyrimidine substrate of lumazine synthase and product of riboflavin synthase Arindam Talukdar, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Mark Cushman Journal of Organic Chemistry 72, 7167-7175 (2007) |
| 53 |
A new series of 3-alkyl phosphate derivatives of 4,5,6,7-tetrahydro-1-D-ribityl-1H-pyrazolo[3,4-d]pyrimidinedione as inhibitors of lumazine synthase: design, synthesis, and evaluation Yanlei Zhang, Guangyi Jin, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Mark Cushman Journal of Organic Chemistry 72, 7176-7184 (2007) |
| 52 |
Design, synthesis and evaluation of 1-(D-ribityl)-1,7-dihydro-pyrazolo[3,4-d]pyrimidine-4,6-diones bearing alkyl phosphate substituents as inhibitors of lumazine synthase Yanlei Zhang, Adelbert Bacher , Markus Fisher, Boris A. Illarionov , Mark Cushman Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007, MEDI-M059 (2007) |
| 51 |
Design, synthesis, and biochemical evaluation of Lumazine synthase inhibitors as potential antimicrobial agents Arindam Talukdar, Adelbert Bacher , Markus Fisher, Boris A. Illarionov , Mark Cushman Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007, MEDI-M450 (2007) |
2006 | |
| 50 |
Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis Ekaterina Morgunova, Boris A. Illarionov , Thota Sambaiah, Ilka Haase, Adelbert Bacher , Mark Cushman, Markus Fischer , Rudolf Ladenstein FEBS Journal 273, 4790-4804 (2006) |
| 49 |
Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: stereochemical implications Arne Ramsperger, Martin Augustin, Ann-Kathrin Schott, Stefan Gerhardt, Tobias Krojer, Wolfgang Eisenreich, Boris A. Illarionov , Mark Cushman, Adelbert Bacher , Robert Huber, Markus Fischer Journal of Biological Chemistry 281, 1224-1232 (2006) |
| 48 |
Design, synthesis, and biochemical evaluation of ribitylaminopyrimidine substrate analogs of lumazine synthase as potential enzyme inhibitors and mechanistic probes Arindam Talukdar, Adelbert Bacher , Markus Fisher, Boris A. Illarionov , Mark Cushman Abstracts of Papers, 232nd ACS National Meeting, San Francisco, CA, United States, Sept. 10-14, 2006, MEDI-M161 (2006) |
2005 | |
| 47 |
A high-throughput screen utilizing the fluorescence of riboflavin for identification of lumazine synthase inhibitors Jinhua Chen, Boris A. Illarionov , Adelbert Bacher , Markus Fischer , Ilka Haase, Gunda I. Georg, Qi-Zhuang Ye, Zeqiang Ma, Mark Cushman Analytical Biochemistry 338, 124-130 (2005) |
| 46 |
Structures
and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin Markus Fischer , Werner Römisch, Boris A. Illarionov , Wolfgang Eisenreich, Adelbert Bacher Biochemical Society Transactions 33, 780-784 (2005) |
| 45 |
Crystal Structure of Lumazine Synthase from Mycobacterium tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors Ekaterina Morgunova, Winfried Meining, Boris A. Illarionov , Ilka Haase, Guangyi Jin, Adelbert Bacher , Mark Cushman, Markus Fischer , Rudolf Ladenstein Biochemistry 44, 2746-2758 (2005) |
| 44 |
Pre-steady-state kinetic analysis of riboflavin synthase using a pentacyclic reaction intermediate as substrate Boris A. Illarionov , Ilka Haase, Markus Fischer , Adelbert Bacher , Nicholas Schramek Biological Chemistry 386, 127-136 (2005) |
| 43 |
Biosynthesis of Vitamin B2: diastereomeric reaction intermediates of archaeal and non-archaeal riboflavin synthases Boris A. Illarionov , Wolfgang Eisenreich, Nicholas Schramek, Adelbert Bacher , Markus Fischer Journal of Biological Chemistry 280, 28541-28546 (2005) |
| 42 |
Design, synthesis, and biochemical evaluation of 1,5,6,7-tetrahydro-6,7-dioxo-9-D-ribitylaminolumazines bearing alkyl phosphate substituents as inhibitors of lumazine synthase and riboflavin synthase Mark Cushman, Guangyi Jin, Boris A. Illarionov , Markus Fischer , Rudolf Ladenstein, Adelbert Bacher Journal of Organic Chemistry 70, 8162-8170 (2005) Erratum: Journal of Organic Chemistry 70, 9092-9092 (2005) |
| 41 |
Random Isotopolog Libraries for Protein Perturbation Studies. 13C NMR Studies on Lumazine Protein of Photobacterium leiognathi Boris A. Illarionov , Chan Yong Lee, Adelbert Bacher , Markus Fischer , Wolfgang Eisenreich Journal of Organic Chemistry 70, 9947-9954 (2005) |
| 40 |
Lumazine protein from Photobacterium leiognathi. Localization of the single ligand binding site Boris A. Illarionov , Wolfgang Eisenreich, Martina Wirth, Young-Eun Woo, Chan Yong Lee, Markus Fischer -/- Editor: T. Nishino, R. Miura, M. Tanokura, K. Fukui Flavins and Flavoproteins: Proceedings of the International Symposium, 15th, Shonan Village Center, Hayama, Japan, April 17-22, 2005, 643-648 (2005) |
| 39 |
Evolution of riboflavin biosynthesis: Structures and reaction mechanisms of riboflavin synthases from eubacterial and archaeal kingdom Markus Fischer , Boris A. Illarionov , Werner Römisch, Adelbert Bacher , Wolfgang Eisenreich -/- Editor: T. Nishino, R. Miura, M. Tanokura, K. Fukui Flavins and Flavoproteins: Proceedings of the International Symposium, 15th, Shonan Village Center, Hayama, Japan, April 17-22, 2005, 713-723 (2005) |
| 38 |
Vitamin B2 biosynthesis in plants. The pyrimidine deaminase and the riboflavin synthase of Arabidopsis thaliana Markus Fischer , Werner Römisch, Ilka Haase, Richard Feicht, Nicholas Schramek, P. Koehler, P. Schieberle, Sabine Saller, Boris A. Illarionov , Wolfgang Eisenreich, Adelbert Bacher -/- Editor: T. Nishino, R. Miura, M. Tanokura, K. Fukui Flavins and Flavoproteins: Proceedings of the International Symposium, 15th, Shonan Village Center, Hayama, Japan, April 17-22, 2005, 731-736 (2005) |
| 37 |
Stable isotope labeled flavocoenzymes as probes for flavoprotein spectroscopy: Preparation and use of random and ordered libraries Werner Römisch, Boris A. Illarionov , Gerald Richter, Adelbert Bacher , Markus Fischer , Wolfgang Eisenreich -/- Editor: T. Nishino, R. Miura, M. Tanokura, K. Fukui Flavins and Flavoproteins: Proceedings of the International Symposium, 15th, Shonan Village Center, Hayama, Japan, April 17-22, 2005, 743-747 (2005) |
2004 | |
| 36 |
Evolution of Vitamin B2 Biosynthesis: Structural and Functional Similarity Between Pyrimidine Deaminases of Eubacterial and Plant Origin Markus Fischer , Werner Römisch, Sabine Saller, Boris A. Illarionov , Gerald Richter, Felix Rohdich, Wolfgang Eisenreich, Adelbert Bacher Journal of Biological Chemistry 279, 36299-36308 (2004) |
| 35 |
Design, Synthesis, and Evaluation of 9-D-Ribitylamino-1,3,7,9-tetrahydro-2,6,8-purinetriones Bearing Alkyl Phosphate and α,α-Difluorophosphonate Substituents as Inhibitors of Riboflavin Synthase and Lumazine Synthase Mark Cushman, Thota Sambaiah, Guangyi Jin, Boris A. Illarionov , Markus Fischer , Adelbert Bacher Journal of Organic Chemistry 69, 601-612 (2004) |
| 34 |
Rapid Preparation of Isotopolog Libraries by in Vivo Transformation of 13C-Glucose. Studies on 6,7-Dimethyl-8-ribityllumazine, a Biosynthetic Precursor of Vitamin B2 Boris A. Illarionov , Markus Fischer , Chan Yong Lee, Adelbert Bacher , Wolfgang Eisenreich Journal of Organic Chemistry 69, 5588-5594 (2004) |
| 33 |
Design, Synthesis, and Evaluation of Acyclic C-Nucleoside and N-Methylated Derivatives of the Ribitylaminopyrimidine Substrate of Lumazine Synthase as Potential Enzyme Inhibitors and Mechanistic Probes Jinhua Chen, Thota Sambaiah, Boris A. Illarionov , Markus Fischer , Adelbert Bacher , Mark Cushman Journal of Organic Chemistry 69, 6996-7003 (2004) |
| 32 |
Design and synthesis of ligands to probe the active site of lumazine synthase Mark Cushman, Jinhua Chen, Thota Sambaiah, Adelbert Bacher , Boris A. Illarionov Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004, MEDI-M078 (2004) |
2003 | |
| 31 |
Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments Markus Fischer , Ann-Kathrin Schott, Kristina Kemter, Richard Feicht, Gerald Richter, Boris A. Illarionov , Wolfgang Eisenreich, Stefan Gerhardt, Mark Cushman, Stefan Steinbacher, Robert Huber, Adelbert Bacher BMC Biochemistry 4, 18-18 (2003) |
| 30 |
Presteady State Kinetic Analysis of Riboflavin Synthase Boris A. Illarionov , Ilka Haase, Adelbert Bacher , Markus Fischer , Nicholas Schramek Journal of Biological Chemistry 278, 47700-47706 (2003) |
2002 | |
| 29 |
Studies on the Reaction Mechanism of Riboflavin Synthase. X-Ray Crystal Structure of a Complex with 6-Carboxyethyl-7-Oxo-8-Ribityllumazine Stefan Gerhardt, Ann-Kathrin Schott, Norman Kairies, Mark Cushman, Boris A. Illarionov , Wolfgang Eisenreich, Adelbert Bacher , Robert Huber, Stefan Steinbacher, Markus Fischer Structure 10, 1371-1381 (2002) |
| 28 |
The crystal structure of riboflavin synthase of Schizosaccharomyces pombe in complex with 6-carboxyethyl-7-oxo-8-ribityllumazine reveals insights into the reaction mechanism Stefan Gerhardt, Stefan Steinbacher, N. Kairies, Robert Huber, Ann-Kathrin Schott, Boris A. Illarionov , Wolfgang Eisenreich, Adelbert Bacher , Markus Fischer , Mark Cushman -/- Editor: Stephen Chapman, Richard Perham, Nigel Scrutton Flavins and Flavoproteins 2002, Proceedings of the International Symposium, 14th, Cambridge, United Kingdom, July 14-18, 2002, 45-50 (2002) |
| 27 |
19F NMR ligand perturbation studies on the riboflavin synthase of Schizosaccharomyces pombe Markus Fischer , Ann-Kathrin Schott, Kristina Kemter, Richard Feicht, Gerald Richter, Boris A. Illarionov , Wolfgang Eisenreich, Adelbert Bacher , Stefan Gerhardt, Stefan Steinbacher, Robert Huber, Mark Cushman -/- Editor: Stephen Chapman, Richard Perham, Nigel Scrutton Flavins and Flavoproteins 2002, Proceedings of the International Symposium, 14th, Cambridge, United Kingdom, July 14-18, 2002, 161-166 (2002) |
| 26 |
Single turnover kinetic analysis of riboflavin synthase from Escherichia coli Boris A. Illarionov , Ilka Haase, Wolfgang Eisenreich, Markus Fischer , Adelbert Bacher , Nicholas Schramek -/- Editor: Stephen Chapman, Richard Perham, Nigel Scrutton Flavins and Flavoproteins 2002, Proceedings of the International Symposium, 14th, Cambridge, United Kingdom, July 14-18, 2002, 223-228 (2002) |
2001 | |
| 25 |
Role of conservative residue Cys158 in the formation of an active photoprotein complex of obelin Vladimir S. Bondar, Konstantin V. Purtov, Natalia P. Malikova, Ludmila A. Frank, Boris A. Illarionov Biochemistry (Moscow) 66, 1014-1018 (2001) Translated: Biokhimiya 66, 1245-1251 (2001) |
| 24 |
Riboflavin synthase of Escherichia coli. Effect of single amino acid substitutions on reaction rate and ligand binding properties Boris A. Illarionov , Kristina Kemter, Sabine Eberhardt, Gerald Richter, Mark Cushman, Adelbert Bacher Journal of Biological Chemistry 276, 11524-11530 (2001) |
| 23 |
A pentacyclic reaction intermediate of riboflavin synthase Boris A. Illarionov , Wolfgang Eisenreich, Adelbert Bacher Proceedings of the National Academy of Sciences of the United States of America 98, 7224-7229 (2001) |
| 22 |
Biosynthesis of riboflavin Adelbert Bacher , Sabine Eberhardt, Wolfgang Eisenreich, Markus Fischer , Stefan Herz, Boris A. Illarionov , Klaus Kis, Gerald Richter Vitamins and Hormones 61, 1-49 (2001) |
| 21 |
All three calcium-binding sites participate in the regulation of obelin luminescence Boris A. Illarionov , Victoria A. Illarionova, Vladimir S. Bondar, Eugene S. Vysotski, John R. Blinks Bioluminescence & Chemiluminescence, Proceedings of the International Symposium, 11th, Pacific Grove, CA, United States, Sept. 6-10, 2000 75-78 (2001) |
| 20 |
Where does manganese bind when it triggers the luminescence of calcium-regulated photoproteins? Boris A. Illarionov , Victoria A. Illarionova, Vladimir S. Bondar, Eugene S. Vysotski, John R. Blinks Bioluminescence & Chemiluminescence, Proceedings of the International Symposium, 11th, Pacific Grove, CA, United States, Sept. 6-10, 2000 79-82 (2001) |
2000 | |
| 19 |
Recombinant obelin: cloning and expression of cDNA, purification, and characterization as a calcium indicator Boris A. Illarionov , Ludmila A. Frank, Victoria A. Illarionova, Vladimir S. Bondar, Eugene S. Vysotski, John R. Blinks Methods in Enzymology 305 (Bioluminescence and Chemiluminescence, Part C) 223-249 (2000) |
1997 | |
| 18 |
Characterization of recombinant obelin as an intracellular Ca++ indicator Victoria A. Illarionova, Boris A. Illarionov , Vladimir S. Bondar, Eugene S. Vysotski, John R. Blinks Bioluminescence and Chemiluminescence: Molecular Reporting with Photons, Proceedings of the International Symposium on Bioluminescence and Chemiluminescence, 9th, Woods Hole, Mass., Oct. 4-8, 1996, 427-430 (1997) |
| 17 |
Removal of essential ligand in N-terminal calcium-binding domain of obelin does not inactivate the photoprotein or reduce its calcium sensitivity, but dramatically alters the kinetics of the luminescent reaction Victoria A. Illarionova, Boris A. Illarionov , Vladimir S. Bondar, Eugene S. Vysotski, John R. Blinks Bioluminescence and Chemiluminescence: Molecular Reporting with Photons, Proceedings of the International Symposium on Bioluminescence and Chemiluminescence, 9th, Woods Hole, Mass., Oct. 4-8, 1996, 431-434 (1997) |
| 16 |
Obelin as a carrier protein and reporter enzyme for in vitro synthesized small bioactive polypeptides: new approach to obtain sarcotoxin Boris A. Illarionov , Sergey V. Matveev, Vladimir S. Bondar, V. A. Skosyrev, Yuliy B. Alakov Bioluminescence and Chemiluminescence: Molecular Reporting with Photons, Proceedings of the International Symposium on Bioluminescence and Chemiluminescence, 9th, Woods Hole, Mass., Oct. 4-8, 1996, 435-438 (1997) |
| 15 |
A strain of Escherichia coli for manufacture of luciferase Boris A. Illarionov , Natalya A. Tyulkova Patent: RU 2073714 (C1) 1997-02-20 |
1995 | |
| 14 |
Obelin mRNA-a new tool for studies of translation in cell-free systems Sergey V. Matveev, Boris A. Illarionov , Eugene S. Vysotski, Vladimir S. Bondar, Svetlana V. Markova, Yuliy B. Alakov Analytical Biochemistry 231, 34-39 (1995) |
| 13 |
Mn2+-activated luminescence of the photoprotein obelin Eugene S. Vysotski, Constantin P. Trofimov, Vladimir S. Bondar, Ludmila A. Frank, Svetlana V. Markova, Boris A. Illarionov Archives of Biochemistry and Biophysics 316, 92-99 (1995) |
| 12 |
Cadmium-induced luminescence of recombinant photoprotein obelin Vladimir S. Bondar, Andrey G. Sergeev, Boris A. Illarionov , Jacques Vervoort, Wilfred R. Hagen Biochimica et Biophysica Acta, Bioenergetics 1231, 29-32 (1995) |
| 11 |
Sequence of the cDNA encoding the Ca2+-activated photoprotein obelin from the hydroid polyp Obelia longissima Boris A. Illarionov , Vladimir S. Bondar, Victoria A. Illarionova, Eugene S. Vysotski Gene 153, 273-274 (1995) |
1994 | |
| 10 |
Expression and properties of the recombinant lumazine (riboflavin) protein from Photobacterium leiognathi Boris A. Illarionov , Victoria A. Illarionova, John Lee, Walter van Dongen, Jacques Vervoort Biochimica et Biophysica Acta, General Subjects 1201, 251-258 (1994) |
| 9 |
Calcium-activated photoprotein obelin derivatives in immunoassay: Perspectives Ludmila A. Frank, Svetlana V. Markova, Victoria A. Illarionova, Boris A. Illarionov , Eugene S. Vysotski Bioluminescence and Chemiluminescence: Fundamentals and Applied Aspects, Proceedings of the International Symposium on Bioluminescence and Chemiluminescence, 8th, Cambridge, UK, Sept. 5-8, 1994, 249-252 (1994) |
| 8 |
Light emission of the recombinant obelin from hydroid polyp Obelia longissima initiated by Cd2+ ions Constantin P. Trofimov, Vladimir S. Bondar, Boris A. Illarionov , Eugene S. Vysotski Bioluminescence and Chemiluminescence: Fundamentals and Applied Aspects, Proceedings of the International Symposium on Bioluminescence and Chemiluminescence, 8th, Cambridge, UK, Sept. 5-8, 1994, 600-603 (1994) |
1993 | |
| 7 |
Cloning, expression and nucleotide sequence investigation of apoobelin cDNA from the hydroid Obelia longissima Boris A. Illarionov , Svetlana V. Markova, Vladimir S. Bondar, Victoria A. Illarionova, Eugene S. Vysotski Bioluminescence and Chemiluminescence: Status Report, Proceedings of the International Symposium on Bioluminescence and Chemiluminescence, 7th, Banff, Alta., March 14-18, 1993, 183-185 (1993) |
1992 | |
| 6 |
Cloning and expression of cDNA coding for the calcium-activated photoprotein obelin from the hydroid polyp Obelia longissima Boris A. Illarionov , Svetlana V. Markova, Vladimir S. Bondar, Eugene S. Vysotski, I. I. Gitel'son Doklady Akademii Nauk 326, 911-913 (1992) |
1991 | |
| 5 |
An efficient method for localized mutagenesis S. I. Tatkov, O. Yu. Smirnova, Boris A. Illarionov , A. A. Ilyichev, V. A. Petrenko Nucleic Acids Symposium Series 254-254 (1991) |
1990 | |
| 4 |
Isolation of bioluminescent functions from Photobacterium leiognathi: analysis of luxA, luxB, and luxG and neighboring genes Boris A. Illarionov , V. M. Blinov, A. P. Donchenko, M. V. Protopopova, V. A. Karginov, N. P. Mertvetsov, I. I. Gitel'son Gene 86, 89-94 (1990) |
1988 | |
| 3 |
Nucleotide sequence of genes of the luciferase α and β subunits from Photobacterium leiognathi Boris A. Illarionov , M. V. Protopopova, V. A. Karginov, N. P. Mertvetsov, I. I. Gitel'son Bioorganicheskaya Khimiya 14, 412-415 (1988) |
| 2 |
Nucleotide sequence of part of Photobacterium leiognathi lux region Boris A. Illarionov , M. V. Protopopova, V. A. Karginov, N. P. Mertvetsov, I. I. Gitel'son Nucleic Acids Research 16, 9855-9855 (1988) |
1987 | |
| 1 |
Cloning and expression of the luminescence system genes from Photobacterium leiognathi Boris A. Illarionov , M. V. Protopopova Molecular Genetics, Microbiology and Virology (8) 41-46 (1987) |