Fachbereich Chemie
Publikationen von Chris Meier
.
| Suche: FB Chemie / Hamburg | |
| 2024 | |
| 281 |
Meeting report of the 37th International Conference on Antiviral Research in Gold Coast, Australia, May 20-24, 2024, organized by the International Society for Antiviral Research Stephen R. Welch, John P. Bilello, Kara Carter, Leen Delang, Larissa Dirr, David Durantel, Joy Y. Feng, Brian B. Gowen, Lara J. Herrero, Zlatko Janeba, Gerald Kleymann, Alpha A. Lee, Chris Meier , Jennifer Moffat, Luis M. Schang, Joshua T. Schiffer, Katherine L. Seley-Radtke, Timothy P. Sheahan, Jessica R. Spengler Antiviral Research 232, 106037 (136 pp) (2024) |
| 280 |
Out of the Dark, into the Light: Metabolic Fluorescent Labeling of Nucleic Acids J. Iven H. Knaack, Chris Meier ChemMedChem 19, e202400160 (10 pp) (2024) |
| 279 |
Membrane-permeable tenofovir-di- and monophosphate analogues Xiao Jia , Giuliano A. Kullik, Marianna Bufano, Andrea Brancale, Dominique Schols, Chris Meier European Journal of Medicinal Chemistry 264, 116020 (24 pp) (2024) |
| 278 |
Antiviral Activity of Lipophilic Nucleoside Tetraphosphate Compounds Xiao Jia , Dominique Schols, Chris Meier Journal of Medicinal Chemistry 67, 2864-2883 (2024) |
| 277 |
MASTER-NAADP: a membrane permeable precursor of the Ca2+ mobilizing second messenger NAADP Sarah Krukenberg, Franziska Möckl, Mariella Weiß, Patrick Dekiert, Melanie Hofmann, Fynn Gerlach, Kai J. Winterberg , Dejan Kovacevic, Imrankhan Khansahib, Berit Troost, Macarena Hinrichs, Viviana Granato, Mikolaj Nawrocki, Tobis Hub, Volodymyr Tsvilovskyy, Rebekka Medert, Lena-Marie Woelk, Fritz Förster, Huan Li, René Werner, Marcus Altfeld, Samuel Huber , Oliver Biggs Clarke, Marc Freichel, Björn-Philipp Diercks, Chris Meier , Andreas H. Guse Nature Communications 15, 8008 (2024) |
| 276 |
Potent Anti-HIV Activity of Alkyl-Modified DiPPro-Nucleotides Xiao Jia , Dominique Schols, Chris Meier Small Structures 5, 2300430 (14 pp) (2024) |
| 275 |
Diphosph(on)ate derivatives as macrodomain inhibitors Chris Meier , Ralf Fliegert, Sahra Jasmin Tajdar, Maximilian Sandmann, Benedikt Ganter, Marina Ocenas -/- Anmelder: Universitätsklinikum Hamburg-Eppendorf Patent: EP 24157879.8 |
| 274 |
Nucleoside diphosphate or diphosphonate prodrugs, or nucleoside analogue diphosphate or diphosphonate prodrugs Chris Meier , Xiao Jia -/- Anmelder: Universität Hamburg Patent: EP 4356928 (A1) 2024-04-24 |
2023 | |
| 273 |
Lipophilic Nucleoside Triphosphate Prodrugs of Anti-HIV. Active Nucleoside Analogs as Potential Antiviral Compounds Xiao Jia , Dominique Schols, Chris Meier Advanced Science 10, 2306021 (14 pp) (2023) |
| 272 |
A TriPPPro-Nucleotide Reporter with Optimized Cell-Permeable Dyes for Metabolic Labeling of Cellular and Viral DNA in Living Cells Vincente Sterrenberg, Dörte Stalling, J. Iven H. Knaack, Timothy K. Soh, Jens B. Bosse, Chris Meier Angewandte Chemie, International Edition 62, e202308271 (9 pp) (2023) Reprint: Nature Chemical Biology 19, 1043-1043 (2023) |
| 271 |
Meeting report: 35th International Conference on Antiviral Research in Seattle, Washington, USA - March 21-25, 2022 Jessica R. Spengler, Stephen R. Welch, Jerome Deval, Brian G. Gentry, Andrea Brancale, Kara Carter, Jennifer Moffat, Chris Meier , Katherine L. Seley-Radtke, Luis M. Schang Antiviral Research 211, 105521 (20 pp) (2023) |
| 270 |
Meeting report: 36th International Conference on Antiviral Research in Lyon, France - March 13-17, 2023 Jessica R. Spengler, Kara Carter, Leen Delang, David Durantel, Brian B. Gowen, Lara J. Herrero, Brett Hurst, Zlatko Janeba, Robert Jordan, Dahai Luo, Chris Meier , Jennifer Moffat, Joana Rocha-Pereira, Katherine L. Seley-Radtke, Stephen R. Welch, Luis M. Schang Antiviral Research 217, 105678 (20 pp) (2023) |
| 269 |
Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106 Tomas Kouba, Anna Dubankova, Petra Drncova, Elisa Donati, Pietro Vidossich, Valentina Speranzini, Alex Pflug, Johanna Huchting , Chris Meier , Marco de Vivo, Stephen Cusack Cell Reports 42, 111901 (23 pp) (2023) |
| 268 |
Pronucleotides of 2',3'-Dideoxy-2',3'-Didehydrothymidine as Potent Anti-HIV Compounds Xiao Jia , Dominique Schols, Chris Meier Journal of Medicinal Chemistry 66, 12163-12184 (2023) |
| 267 |
T-705-Derived Prodrugs Show High Antiviral Efficacies against a Broad Range of Influenza A Viruses with Synergistic Effects When Combined with Oseltamivir Benedikt Ganter, Martin Zickler, Johanna Huchting , Matthias Winkler, Anna Lüttjohann, Chris Meier , Gülsah Gabriel, Sebastian Beck Pharmaceutics 15, 1732 (27 pp) (2023) |
| 266 |
First and Second Generation Nucleoside Triphosphate Prodrugs: TriPPPro-Compounds for Antiviral Chemotherapy Xiao Jia , Chenglong Zhao, Chris Meier Handbook of Chemical Biology of Nucleic Acids online: 17 February 2023 (2023) |
| 265 |
5-Fluorouracil derivatives as prodrugs for cancer treatment Chris Meier , Udo Schumacher, Julian Witt, Maria Roßmeier, Simon Remus -/- Anmelder: Universität Hamburg, Universitätsklinikum Hamburg-Eppendorf Patent: WO 2023041786 (A1) 2023-03-23; EP 4151646 (A1) 2023-03-22 |
| 264 |
Dihydroorotate dehydrogenase (DHODH) inhibitors and their use as antiviral agents Chris Meier , Nora Constanze Laubach, Desiree Rijono -/- Anmelder: Universität Hamburg Patent: WO 2023285371 (A1) 2023-01-19; EP 4119138 (A1) 2023-01-18 |
2022 | |
| 263 |
Triphosphate Prodrugs of the Anti-HIV-Active Compound 3'-Deoxy-3'-fluorothymidine (FLT) Simon Weising, Stefan Weber , Dominique Schols, Chris Meier Journal of Medicinal Chemistry 65, 12163-12175 (2022) |
| 262 |
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation Feng Gu, Aileen Krüger, Hannes G. Roggenkamp, Rick Alpers, Dmitri Lodygin, Vincent Jaquet, Franziska Möckl, Lola C. Hernandez C., Kai J. Winterberg , Andreas Bauche, Anette Rosche, Helmut Grasberger, John Y. Kao, Daniel Schetelig, René Werner, Katrin Schröder, Michael Carty, Andrew G. Bowie, Samuel Huber , Chris Meier , Hans-Willi Mittrücker , Jörg Heeren , Karl-Heinz Krause, Alexander Flügel, Björn-Philipp Diercks, Andreas H. Guse Science Signaling 14, 709 (15 pp) (2022) |
2021 | |
| 261 |
Highly selective fluorescent peptide-based chemosensors for aluminium ions in aqueous solution Sorour Ramezanpour, Hamed Barzinmehr, Pezhman Shiri, Chris Meier , Seyed Abdulmajid Ayatollahi, Mehrdad Mehrazar Analytical and Bioanalytical Chemistry 413, 3881-3891 (2021) |
| 260 |
Trans-Ned 19-Mediated Antagonism of Nicotinic Acid Adenine Nucleotide-Mediated Calcium Signaling Regulates Th17 Cell Plasticity in Mice Mikolaj Nawrocki, Niels Lory, Tanja Bedke, Friederike Stumme, Björn-Phillip Diercks, Andreas H. Guse , Chris Meier , Nicola Gagliani, Hans-Willi Mittrücker , Samuel Huber Cells 10, 3039 (19 pp) (2021) |
| 259 |
γ-Non-symmetrically dimasked TriPPPro-prodrugs as potential antivirals against HIV Chenglong Zhao, Xiao Jia , Dominique Schols, Jan Balzarini, Chris Meier ChemMedChem 16, 499-512 (2021) |
| 258 |
High Content Analysis of Macrophage-Targeting EhPIb-Compounds against Cutaneous and Visceral Leishmania Species Helena Fehling, Hanno Niss, Annika Bea, Nadine Kottmayr, Christine Brinker, Stefan Hoenow, Julie Sellau, Tim-Wolf Gilberger, Frederic Ting, Dirk Landschulze, Chris Meier , Joachim Clos, Hannelore Lotter Microorganisms 9, 422 (16 pp) (2021) |
| 257 |
HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation Hannes G. Roggenkamp, Imrankhan Khansahib, Lola Hernandez, Yunpeng Zhang, Dmitri Lodygin, Aileen Krüger, Feng Gu, Franziska Möckl, Anke Löhndorf, Valerie Wolters, Daniel Woike, Anette Rosche, Andreas Bauche, Daniel Schetelig, René Werner, Hartmut Schlüter , Antonio V. Failla, Chris Meier , Ralf Fliegert, Timothy F. Walseth, Alexander Flügel, Björn-Philipp Diercks, Andreas H. Guse Science Signaling 14 (12 pp) 675 (2021) |
| 256 |
Improving properties of the nucleobase analogs T-705/T-1105 as potential antiviral Xiao Jia , Benedikt Ganter, Chris Meier -/- Herausgeber: Katherine L. Seley-Radtke Annual Reports in Medicinal Chemistry 57 (Coronaviruses and other Novel Antiviral Targets) 1-46 (2021) |
2020 | |
| 255 |
Prodrugs of γ-Alkyl-modified Nucleoside Triphosphates - improved Inhibition of HIV Reverse Transcriptase Chris Meier , Chenglong Zhao, Stefan Weber , Dominique Schols, Jan Balzarini Angewandte Chemie, International Edition 59, 22063-22071 (2020) Translated: Angewandte Chemie 132, 22247-22255 (2020) |
| 254 |
Anti-leishmanial effects of synthetic EhPIb analogs derived from the Entamoeba histolytica lipopeptidephosphoglycan (Editor's Pick) Helena Fehling, Siew Ling Choy, Frederic Ting, Dirk Landschulze, Hannah Bernin, Sarah Corinna Lender, Melina Mühlenpfordt, Eugenia Bifeld, Julia Eick, Claudia Marggraff, Nadine Kottmayr, Marie Groneberg, Stefan Hoenow, Julie Sellau, Joachim Clos, Chris Meier , Hannelore Lotter Antimicrobial Agents and Chemotherapy 64, 00161-20 (12 pp) (2020) |
| 253 |
Photocaged and mixed photocaged-bioreversible protected ATP derivatives as tools for the controlled intra-, and extracellular release of ATP Nils Jeschik, Tobias Schneider, Chris Meier European Journal of Organic Chemistry 6776-6789 (2020) |
| 252 |
Contribution of NAADP to Glutamate-Evoked Changes in Ca2+ Homeostasis in Mouse Hippocampal Neurons Julia Hermann, Melanie Bender, Dagmar Schumacher, Marcel S. Woo, Artem Shaposhnykov, Sina C. Rosenkranz, Vladimir Kuryshev, Chris Meier , Andreas H. Guse , Manuel A. Friese, Marc Freichel, Volodymyr Tsvilovskyy Frontiers in Cell and Developmental Biology 8, 496 (13 pp) (2020) (Research Topic: Emerging Roles of TRP Channels in Brain Pathology) |
| 251 |
Anti-HIV-active Nucleoside Triphosphate Prodrugs Xiao Jia , Dominique Schols, Chris Meier Journal of Medicinal Chemistry 63, 6003-6027 (2020) |
| 250 |
Lipophilic Triphosphate Prodrugs of Various Nucleoside Analogues Xiao Jia , Dominique Schols, Chris Meier Journal of Medicinal Chemistry 63, 6991-7007 (2020) |
| 249 |
Membrane Permeable, Bioreversibly Modified Prodrugs of Nucleoside Diphosphate-γ-Phosphonates Xiao Jia , Stefan Weber , Dominique Schols, Chris Meier Journal of Medicinal Chemistry 63, 11990-12007 (2020) |
| 248 |
γ-Ketobenzyl-Modified Nucleoside Triphosphate Prodrugs as Potential Antivirals Tobias Nack, Thiago Dinis de Oliveira, Stefan Weber , Dominique Schols, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 63, 13745-13761 (2020) |
| 247 |
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis Ashleigh Shannon, Barbara Selisko, Thi-Tuyet-Nhung Le, Johanna Huchting , Franck Touret, Géraldine Piorkowski, Véronique Fattorini, Francois Ferron, Etienne Decroly, Chris Meier , Bruno Coutard, Olve Peersen, Bruno Canard Nature Communications 11, 4682 (9 pp) (2020) |
| 246 |
Preparation of aminobenzoates and aminopyridinecarboxylates as DHODH inhibitors and their use as antiviral agents Chris Meier , Matthias Winkler, Katharina Pfaff, Nora Constanze Fohrmann, Gilles Querat, Xavier de Lamballerie -/- Anmelder: Universität Hamburg, Aix-Marseille Université Patent: WO 2020225330 (A1) 2020-11-12; LU 2019-0101207 2019-05-07 |
2019 | |
| 245 |
Cell line-dependent activation and antiviral activity of T-1105, the non-fluorinated analogue of T-705 (favipiravir) Johanna Huchting , Evelien Vanderlinden, Ria van Berwaer, Chris Meier , Lieve Naesens Antiviral Research 167, 1-5 (2019) |
| 244 |
Meeting report: 32nd International Conference on Antiviral Research Enzo Tramontano, Bart Tarbet, Jessica R. Spengler, Katherine L. Seley-Radtke, Chris Meier , Robert Jordan, Zlatko Janeba, Brian Gowen, Brian Gentry, José A. Esté, Mike Bray, Graciela Andrei, Luis M. Schang Antiviral Research 169, 104550 (2019) |
| 243 |
Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation Ralf Fliegert, Jörg Heeren , Friedrich Koch-Nolte , Viacheslav O. Nikolaev , Christian Lohr, Chris Meier , Andreas H. Guse Biochemical Society Transactions 47, 329-337 (2019) |
| 242 |
Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer Leonie Konczalla, Daniel R. Perez, Nadine Wenzel, Gerrit Wolters-Eisfeld, Clarissa Klemp, Johanna Lüddeke, Annika Wolski, Dirk Landschulze, Chris Meier , Anika Buchholz, Dichao Yao, Bianca T. Hofmann, Julia K. Graß, Sarah L. Spriestersbach, Katharina Grupp, Udo Schumacher, Christian Betzel , Svetlana Kapis, Theresa Nuguid, Pablo Steinberg, Klaus Püschel, Guido Sauter, Maximillian Bockhorn, Faik G. Uzunoglu, Jakob R. Izbicki, Cenap Güngör, Alexander T. el Gammal International Journal of Cancer 146, 1618-1630 (2019) |
2018 | |
| 241 |
Synthesis and Antiviral Evaluation of TriPPPro-AbacavirTP, TriPPPro-CarbovirTP and their 1',2'-cis-disubstituted Analogues Simon Weising, Vincente Sterrenberg, Dominique Schols, Chris Meier ChemMedChem 13, 1771-1778 (2018) |
| 240 |
Prodrugs of the Phosphoribosylated Forms of Hydroxypyrazinecarboxamide Pseudobase T-705 and its De-Fluoro-Analogue T-1105 as Potent Influenza Virus Inhibitors Johanna Huchting , Evelien Vanderlinden, Matthias Winkler, Hiba Nasser, Lieve Naesens, Chris Meier Journal of Medicinal Chemistry 61, 6193-6210 (2018) |
| 239 |
Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays Alexandra Ruthenbeck, Elisa Marangoni, Björn-Philipp Diercks, Aileen Krüger, Alexander Froese, Nadja I. Bork, Viacheslav O. Nikolaev , Andreas H. Guse , Chris Meier Molecules 23, 2960 (20 pp) (2018) |
| 238 |
ORAI1, STIM1/2, and RYR1 shape sub-second Ca2+ microdomains upon T cell activation Björn-Philipp Diercks, René Werner, Paula Weidemüller, Frederik Czarniak, Lola Hernandez, Cari Lehmann, Anette Rosche, Aileen Krüger, Ulrike Kaufmann, Martin Vaeth, Antonio V. Failla, Bernd Zobiak, Farid I. Kandil, Daniel Schetelig, Alexandra Ruthenbeck, Chris Meier , Dmitri Lodygin, Alexander Flügel, Dejian Ren, Insa M. A. Wolf, Stefan Feske, Andreas H. Guse Science Signaling 11, 561 (13 pp) (2018) |
| 237 |
Stereoselective Synthesis of 1',2'-cis-Disubstituted Carbocyclic ribo-Nucleoside Analogues Simon Weising, Ilaria Torquati, Chris Meier Synthesis 50, 1264-1274 (2018) |
| 236 |
Synthesis of Enantiomerically Pure 1',2'-cis-dideoxy, -dideoxydidehydro, -ribo and -deoxy Carbocyclic Nucleoside Analogues Simon Weising, Patrick Dekiert, Dominique Schols, Johan Neyts, Chris Meier Synthesis 50, 2266-2280 (2018) |
| 235 |
Enhancing the Efficacy of Anti-Viral & Anti-Cancer Drugs Chris Meier Scientia 118, 75-78 (2018) |
| 234 |
Nucleoside triphosphate and nucleoside triphosphate analogue prodrugs Chris Meier , Tobias Nack, Thiago Dinis de Oliveira, Chenglong Zhao -/- Anmelder: Universität Hamburg Patent: WO 2018100137 (A1) 2018-06-07; LU 93331 (B1) 2018-06-05 |
2017 | |
| 233 |
Nucleoside
diphosphate and triphosphate prodrugs - An unsolvable task? Chris Meier Antiviral Chemistry & Chemotherapy 25, 69-82 (2017) |
| 232 |
Exploring and Exploiting Acceptor Preferences of the Human Polysialyltransferases as a Basis for an Inhibitor Screen Jörg Ehrit, Timothy G. Keys, Mark Sutherland, Saskia Wolf, Chris Meier , Robert A. Falconer, Rita Gerardy-Schahn ChemBioChem 18, 1332-1337 (2017) |
| 231 |
Synthesis of a bioreversible masked, lipophilic Adenosine Diphosphate Ribose Derivative Chris Meier , Katharina Pahnke ChemBioChem 18, 1616-1626 (2017) |
| 230 |
Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl-ureidothiophene-carboxylic acids Alexandra Ruthenbeck, Walid A. M. Elgaher, Jörg Haupenthal, Rolf W. Hartmann, Chris Meier ChemistrySelect 2, 11899-11906 (2017) |
| 229 |
Synthesis of the T-705-Ribonucleoside and -Ribonucleotide and Studies on the Chemical Stability Johanna Huchting , Matthias Winkler, Hiba Nasser, Chris Meier ChemMedChem 12, 652-659 (2017) Cover Picture: ChemMedChem 12, 621-621 (2017) |
| 228 |
SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells Paula Ordonez, Simone Kunzelmann, Harriet C. T. Groom, Melvyn W. Yap, Simon Weising, Chris Meier , Kate N. Bishop, Ian A. Taylor, Jonathan P. Stoye Scientific Reports 7, 42824 (2017) |
2016 | |
| 227 |
Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues Tristan Gollnest, Thiago Dinis de Oliveira, Anna Katharina Rath, Ilona Hauber, Dominique Schols, Jan Balzarini, Chris Meier Angewandte Chemie, International Edition 55, 5255-5258 (2016) Translated: Angewandte Chemie 128, 5341-5344 (2016) |
| 226 |
Linker-region modified Derivatives of the Deoxyhypusine Synthase Inhibitor CNI-1493 Suppress HIV-1 Replication Marcus Schröder, Adrian Kolodzik, Björn Windshügel, Marcel Krepstakies, Poornima Priyadarshini, Philip Hartjen, Jan van Lunzen, Matthias Rarey , Joachim Hauber, Chris Meier Archiv der Pharmazie 349, 91-103 (2016) |
| 225 |
Solid-phase synthesis of DNA and RNA 5'-O-triphosphates using cycloSal chemistry Ivo Sarac, Chris Meier Current Protocols in Nucleic Acid Research 64, 4.67.1-4.67.13 (2016) |
| 224 |
Di- and triphosphate prodrugs (Di- und Triphosphat-Propharmaka) Chris Meier , Tristan Gollnest, Tobias Nack, Lina Weinschenk -/- Anmelder: Universität Hamburg Patent: WO 2016026493 (A1) 2016-02-25; CN 106661075 (A) 2017-05-10; DE 102014112055 (A1) 2016-02-25; EP 3183257 (A1) 2017-06-28; US 2017275328 (A1) 2017-09-28 |
2015 | |
| 223 |
Tagging Glycoproteins by α1,3-Fucosyltransferases with Fluorescently labeled GDP-Fucoses Katrin Seelhorst, Katharina Pahnke, Chris Meier , Ulrich Hahn ChemBioChem 16, 1919-1924 (2015) |
| 222 |
Synthesis of C8-N-Arylamine-Modified 2'-Deoxyguanosine-5'-Triphosphates and Their Effects on Primer Extension by DNA Polymerases Katharina Höfler, Ivo Sarac, Chris Meier ChemBioChem 16, 2046-2053 (2015) |
| 221 |
Efficient Automated Solid-Phase Synthesis of DNA and RNA 5'-Triphosphates Ivo Sarac, Chris Meier Chemistry - A European Journal 21, 16421-16426 (2015) |
| 220 |
Nucleoside Mono- and Diphosphate Prodrugs of 2',3'-Dideoxyuridine and 2',3'-Dideoxy-2',3'-didehydrouridine Florian Pertenbreiter, Jan Balzarini, Chris Meier ChemMedChem 10, 94-106 (2015) |
| 219 |
Bis(benzoyloxybenzyl)-DiPPro Nucleoside Diphosphates of Anti-HIV Active Nucleoside Analogues Lina Weinschenk, Tristan Gollnest, Dominique Schols, Jan Balzarini, Chris Meier ChemMedChem 10, 891-900 (2015) |
| 218 |
Rational Development of Nucleoside Diphosphate Prodrugs: DiPPro-Compounds Chris Meier , Henning Jacob Jessen, Tilmann Schulz, Lina Weinschenk, Florian Pertenbreiter, Jan Balzarini Current Medicinal Chemistry 22, 3933-3950 (2015) |
| 217 |
Synthesis of Homo-C-Nucleoside Phosphoramidites and their Site-Specific Incorporation into Oligonucleotides Katharina Höfler, Tristan Zimmermann, Dilver Peña Fuentes, Christian Vogel, Chris Meier European Journal of Organic Chemistry 6841-6849 (2015) |
| 216 |
Mouse Siglec-1 Mediates Trans-Infection of Surface-Bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-Dependent Manner Elina Erikson, Paul R. Wratil, Martin Frank, Ina Ambiel, Katharina Pahnke, Maria Pino, Parastoo Azadi, Nuria Izquierdo-Useros, Javier Martinez-Picado, Chris Meier , Ronald L. Schnaar, Paul R. Crocker, Werner Reutter, Oliver T. Keppler Journal of Biological Chemistry 290, 27345-27359 (2015) |
| 215 |
Nucleoside Diphosphate Prodrugs: Non-symmetric DiPPro-Nucleotides Lina Weinschenk, Dominique Schols, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 58, 6114-6130 (2015) |
| 214 |
Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals Tristan Gollnest, Thiago Dinis de Oliveira, Dominique Schols, Jan Balzarini, Chris Meier Nature Communications 6, 8716 (2015) |
2014 | |
| 213 |
Synthesis and analysis of potential α 1,3-fucosyltransferase inhibitors Katrin Seelhorst, Tomas Piernitzki, Nathalie Lunau, Chris Meier , Ulrich Hahn Bioorganic & Medicinal Chemistry 22, 6430-6437 (2014) |
| 212 |
The DiPPro-Approach: Synthesis, Hydrolysis, and Antiviral Activity of Lipophilic d4T Diphosphate Prodrugs Tilmann Schulz, Jan Balzarini, Chris Meier ChemMedChem 9, 762-775 (2014) (rated: very important paper (VIP)) |
| 211 |
In silico Design, Synthesis and Screening of Novel Deoxyhypusine Synthase Inhibitors Targeting HIV-1 Replication Marcus Schröder, Adrian Kolodzik, Katharina Pfaff, Poornima Priyadarshini, Marcel Krepstakies, Joachim Hauber, Matthias Rarey , Chris Meier ChemMedChem 9, 940-952 (2014) |
| 210 |
Synthesis of Pyranonucleoside-6'-Triphosphates via the cycloSal-Method Johanna Huchting , Chris Meier European Journal of Organic Chemistry 3423-3429 (2014) |
| 209 |
Method for the solid-phase based synthesis of phosphate-bridged nucleoside conjugates Chris Meier , Ivo Sarac -/- Anmelder: Universität Hamburg Patent: WO 2014114326 (A1) 2014-07-31; US 2015361124 (A1) 2015-12-17; EP 13701961.8 |
2013 | |
| 208 |
Fluorescently
labeled substrates for monitoring of α1,3-fucosyltransferase IX activity Nathalie Lunau, Katrin Seelhorst, Stefanie Kahl, Kathrin Tscherch, Christina Stacke, Sascha Rohn , Joachim Thiem, Ulrich Hahn , Chris Meier Chemistry - A European Journal 19, 17379-17390 (2013) |
| 207 |
Synthesis of Site-Specific Damaged DNA Strands by 8-(Acetylarylamino)-2'-deoxyguanosine Adducts and Effects on Various DNA Polymerases Sarah Krüger, Chris Meier European Journal of Organic Chemistry 1158-1169 (2013) |
| 206 |
Synthesis of cycloSal-(Glycopyranosyl-6)-Phosphates as activated Sugar Phosphates Johanna Huchting , Alexandra Ruthenbeck, Chris Meier European Journal of Organic Chemistry 6907-6916 (2013) |
| 205 |
A Ubiquitin-specific Protease Possesses a Decisive Role for Adenovirus Replication and Oncogene-mediated Transformation Wilhelm Ching, Emre Koyuncu, Sonia Singh, Cristina Arbelo Román, Barbara Hartl, Elisabeth Kremmer, Thomas Speiseder, Chris Meier , Thomas Dobner PLoS Pathogens 9, e1003273 (2013) |
| 204 |
Chemical Syntheses of Nucleoside Triphosphates Lina Weinschenk, Chris Meier -/- Herausgeber: Pedro Merino Chemical Synthesis of Nucleoside Analogues 209-227 (2013), ISBN 978-1-118-00751-8 , Verlag: John Wiley & Sons |
| 203 |
Deoxyhypusin-Synthese Inhibitoren (Preparation of guanidinoethyl substituted heterocycles as deoxyhypusine synthase inhibitors) Poornima Priyadarshini, Marcus Schröder, Matthias Rarey , Adrian Kolodzik, Joachim Hauber, Marcel Krepstakies, Chris Meier -/- Anmelder: Heinrich-Pette-Institut, Universität Hamburg Patent: DE 102012103405 (A1) 2013-10-24 |
2012 | |
| 202 |
Chemical Synthesis and Enzymatic Testing of CMP-Sialic Acid Derivatives Saskia Wolf, Svenja Warnecke, Jörg Ehrit, Friedrich Freiberger, Rita Gerardy-Schahn, Chris Meier ChemBioChem 13, 700-712 (2012) |
| 201 |
Synthesis of C8-Arylamine-Modified 2'-Deoxyadenosine Phosphoramidites and their Site-Specific Incorporation into Oligonucleotides Zita Szombati, Sabrina Baerns, Andreas Marx, Chris Meier ChemBioChem 13, 700-712 (2012) |
| 200 |
Stereoselective Synthesis of D- and L-Carbocyclic Nucleosides by Enzymatically Catalyzed Kinetic Resolution Miriam Mahler, Bastian Reichardt, Philip Hartjen, Jan van Lunzen, Chris Meier Chemistry - A European Journal 18, 11046-11062 (2012) |
| 199 |
Synthesis of L-Altrose and Some Derivatives Nathalie Lunau, Chris Meier European Journal of Organic Chemistry 6260-6270 (2012) |
| 198 |
Evaluation of Deoxyhypusine Synthase Inhibitors Targeting BCR-ABL Positive Leukemias Patrick Ziegler, Tuhama Chahoud, Thomas Wilhelm, Nora Pällman, Melanie Braig, Valeska Wiehle, Susanne Ziegler, Marcus Schröder, Chris Meier , Adrian Kolodzik, Matthias Rarey , Jens Panse, Joachim Hauber, Stefan Balabanov, Tim H. Brümmendorf Investigational New Drugs 30, 2274-2283 (2012) |
| 197 |
Stereoselective Synthesis and Antiviral Activity of Methyl-Substituted cycloSal-Pronucleotides Edwuin Hander Rios Morales, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 55, 7245-7252 (2012) |
2011 | |
| 196 |
Diastereoselective Synthesis of cycloSaligenyl-Nucleosyl-Phosphotriesters Edwuin Hander Rios Morales, Jan Balzarini, Chris Meier Chemistry - A European Journal 17, 1649-1659 (2011) |
| 195 |
Solid-Phase Synthesis of (Poly)phosphorylated Nucleosides and Conjugates Viktoria Caroline Tonn, Chris Meier Chemistry - A European Journal 17, 9832-9842 (2011) |
| 194 |
Synthesis of 2',3'-Modified Carbocyclic L-Nucleoside Analogues Sönke Jessel, Chris Meier European Journal of Organic Chemistry 1702-1713 (2011) |
| 193 |
Linear Synthesis of Chiral cycloSal-Pronucleotides Edwuin Hander Rios Morales, Cristina Arbelo Román, Jens Oliver Thomann, Chris Meier European Journal of Organic Chemistry 4397-4408 (2011) |
| 192 |
Diastereoselective Synthesis of (Aryloxy)phosphoramidate Prodrugs Cristina Arbelo Román, Philip Wasserthal, Jan Balzarini, Chris Meier European Journal of Organic Chemistry 4899-4909 (2011) |
| 191 |
Synthesis of Nonnatural Nucleoside Diphosphate Sugars Saskia Wolf, Rosmirt Molina Berrio, Chris Meier European Journal of Organic Chemistry 6304-6313 (2011) |
| 190 |
Preventing Fusarium Head Blight of Wheat and Cob Rot of Maize by Inhibition of Fungal Deoxyhypusine Synthase Mayada Woriedh, Ilona Hauber, Ana Lilia Martinez-Rocha, Christian A. Voigt, Frank J. Maier, Marcus Schröder, Chris Meier , Joachim Hauber, Wilhelm Schäfer Molecular Plant-Microbe Interactions 24, 619-627 (2011) |
| 189 |
Verfahren zur stereoselektiven Synthese von Phosphor-Verbindungen (Method for the stereoselective synthesis of phosphorus compounds) Chris Meier , Jens Oliver Thomann -/- Anmelder: Universität Hamburg Patent: DE 112009001327 (A5) 2011-03-31 |
2010 | |
| 188 |
A Chemoenzymatic Synthesis of Carbocyclic Nucleosides and Nucleotides Miriam Mahler, Bastian Reichardt, Jan Balzarini, Chris Meier Antiviral Research 86, A61-A61 (2010) |
| 187 |
D-carba-dT as a Promising New Antiviral Compounds? Chris Meier , Bastian Reichardt, Svenja Warnecke, Miriam Mahler, Stephen H. Hughes, Paul L. Boyer Antiviral Research 86, A62-A62 (2010) |
| 186 |
Nucleoside Diphosphate Prodrugs of Antivirally Active Nucleosides Florian Pertenbreiter, Chris Meier Antiviral Research 86, A64-A64 (2010) |
| 185 |
First Diastereoselective Synthesis of Pronucleotides Edwuin Hander Rios Morales, Cristina Arbelo Román, Jan Balzarini, Chris Meier Antiviral Research 86, A65-A66 (2010) |
| 184 |
Rational Drug Design-Screening and Synthesis of Potential Deoxyhypusine Synthase Inhibitors Targeting HIV-1 Replication Marcus Schröder, Adrian Kolodzik, Björn Windshügel, Marcel Krepstakies, Poornima Priyadarshini, Matthias Rarey , Joachim Hauber, Chris Meier Antiviral Research 86, A67-A67 (2010) |
| 183 |
Lipophilic Nucleoside Diphosphate Prodrugs - Synthesis and Properties Tilmann Schulz, Jan Balzarini, Chris Meier Antiviral Research 86, A67-A68 (2010) |
| 182 |
Stereoselective Synthetic Strategy to Potentially Antiviral Active Carbocyclic L-Nucleosides and L-Nucleotides Claudia Worthmann, Sönke Jessel, Jan Balzarini, Chris Meier Antiviral Research 86, A69-A70 (2010) |
| 181 |
A convenient synthesis of nucleoside diphosphate glycopyranoses and other polyphosphorylated bioconjugates Saskia Wolf, Tanja Zismann, Nathalie Lunau, Svenja Warnecke, Silke Wendicke, Chris Meier European Journal of Cell Biology 89, 63-75 (2010) |
| 180 |
Diastereoselective Synthesis of Aryloxy Phosphoramidate Prodrugs of 3'-Deoxy-2',3'-didehydrothymidine Monophosphate Cristina Arbelo Román, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 53, 7675-7681 (2010) |
| 179 |
Method for producing phosphate-bridged nucleoside conjugates (Verfahren zur Herstellung phosphatverbrückter Nucleosid-Konjugate) Chris Meier , Saskia Wolf, Svenja Warnecke -/- Anmelder: Universität Hamburg Patent: WO 2010015245 (A1) 2010-02-11; DE 102008044914 (A1) 2010-02-11; EP 2321330 (A1) 2011-05-18 |
| 178 |
Procedure for the solid-state-supported production of phosphate-bridged nucleoside conjugates (Verfahren zur festphasengestützten Herstellung phosphatverbrückter Nucleosid-Konjugate) Chris Meier , Viktoria Caroline Tonn -/- Anmelder: Universität Hamburg Patent: WO 2010127666 (A1) 2010-11-11; DE 102009020261 (A1) 2010-11-11; US 2012116067 (A1) 2012-05-10; EP 2427470 (A1) 2012-03-14 |
2009 | |
| 177 |
cycloSaligenyl-di-d4TMP: Highly Loaded cycloSal-pronucleotides that Release Two Equivalents of Nucleotides and Leaving One Masking Unit Chris Meier , Nicolas Gisch, Christian Ducho, Jan Balzarini Antiviral Research 82, A61-A61 (2009) |
| 176 |
Synthesis and Properties of cycloSal-phosphatetriesters of Fluorescent Bicyclic Nucleoside Analogues (BCNAS) Florian Pertenbreiter, Chris Meier Antiviral Research 82, A62-A62 (2009) |
| 175 |
Bioreversible Protection of Nucleosidediphosphates - Synthesis and Properties Tilmann Schulz, Henning Jacob Jessen, Jan Balzarini, Chris Meier Antiviral Research 82, A63-A63 (2009) |
| 174 |
Reliable Synthesis of Various Nucleoside Diphosphate Glycopyranoses Saskia Wolf, Tanja Zismann, Nathalie Lunau, Chris Meier Chemistry - A European Journal 15, 7656-7664 (2009) |
| 173 |
Doubly Loaded cycloSaligenyl-Pronucleotides - 5,5'-Bis-(cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine Monophosphates) Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 52, 3464-3473 (2009) |
| 172 |
The Nucleoside Analogue D-carba T Blocks HIV-1 Reverse Transcription Paul L. Boyer, B. Christie Vu, Zandrea Ambrose, John G. Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier , Victor E. Marquez, Stephen H. Hughes Journal of Medicinal Chemistry 52, 5356-5364 (2009) |
| 171 |
Synthesis of Nucleoside Di- and Triphosphates and Dinucleoside Polyphosphates with cycloSal-Nucleotides Svenja Warnecke, Chris Meier Journal of Organic Chemistry 74, 3024-3030 (2009) |
| 170 |
Synthesis of new cyclic and acyclic 5-halouridine derivatives as potential antiviral agents Mohamed Fathy Elshehry, Jan Balzarini, Chris Meier Synthesis 841-847 (2009) |
| 169 |
Improved process for preparation of enantiopure phosphorus(III) and phosphorus(V) compounds, such as phosphoric derivatives by asymmetric nucleophilic substitution of chiral phosphoramide dichloride auxiliary Chris Meier , Jens Oliver Thomann -/- Anmelder: Universität Hamburg Patent: WO 2009121347 (A1) 2009-10-08 |
| 168 |
Lipophilic masked benzyl esters of nucleoside diphosphates and triphosphates as enzymatically hydrolyzable prodrugs for treatment of viral diseases, AIDS and cancers Chris Meier , Henning Jacob Jessen -/- Anmelder: Universität Hamburg Patent: WO 2009129798 (A2) 2009-10-29; DE 102008020633 (A1) 2009-10-29 |
2008 | |
| 167 |
Efficient synthesis of nucleoside diphosphate glycopyranoses Silke Wendicke, Svenja Warnecke, Chris Meier Angewandte Chemie, International Edition 47, 1500-1502 (2008) Translated: Angewandte Chemie 120, 1523-1525 (2008) |
| 166 |
Bioreversible protection of nucleoside diphosphates Henning Jacob Jessen, Tilmann Schulz, Jan Balzarini, Chris Meier Angewandte Chemie, International Edition 47, 8719-8722 (2008) Translated: Angewandte Chemie 120, 8847-8850 (2008) |
| 165 |
Anti-BK virus activity of nucleoside analogs Parmjeet Randhawa, Jiri Zemlicka, Andreas Sauerbrei, Chris Meier , Karl Y. Hostetler, James R. Beadle, Noush Afarin Farasati, Yuchen Huang, Matthews Bradley Antimicrobial Agents and Chemotherapy 52, 1519-1521 (2008) |
| 164 |
Enzyme-triggered cycloSal-Pronucleotides Chris Meier , Henning Jacob Jessen, Nicolas Gisch, Jan Balzarini Antiviral Research 78, A26-A26 (2008) |
| 163 |
Carbocyclic L-Nucleoside Analogues as Potential Antiviral Agents Sönke Jessel, Chris Meier Antiviral Research 78, A58-A58 (2008) |
| 162 |
A Synthetic Strategy to Different Cyclopentenyl-Nucleosides Bastian Reichardt, Chris Meier Antiviral Research 78, A62-A63 (2008) |
| 161 |
Synthesis and Properties of Glycosyl-functionalised cycloSal-Pronucleotides Tilmann Schulz, Jan Balzarini, Chris Meier Antiviral Research 78, A63-A63 (2008) |
| 160 |
Synthesis of DNA strands site-specifically damaged by C8-arylamine purine adducts and effects on various DNA polymerases Nicolas Böge, Maike I. Jacobsen, Zita Szombati, Sabrina Baerns, Francesca Di Pasquale, Andreas Marx, Chris Meier Chemistry - A European Journal 14, 11194-11208 (2008) |
| 159 |
Intracellular Trapping of cycloSal-Pronucleotides: Modification of Prodrugs with Amino Acid Esters Henning Jacob Jessen, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 51, 6592-6598 (2008) |
| 158 |
Studies on Enzyme-Cleavable Dialkoxymethyl-cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine Monophosphates Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 51, 6752-6760 (2008) |
| 157 |
5-(1-Acetoxyvinyl)-cycloSaligenyl-2',3'-dideoxy-2',3'- didehydrothymidine Monophosphates, a Second Type of New, Enzymatically Activated cycloSaligenyl Pronucleotides Nicolas Gisch, Florian Pertenbreiter, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 51, 8115-8123 (2008) |
| 156 |
Nucleoside diphosphate prodrugs Chris Meier , Henning Jacob Jessen, Jan Balzarini Nucleic Acids Symposium Series 52, 83-84 (2008) |
| 155 |
Synthesis of C8-N-acetylarylamine 2'-dG-adducts and their site-specifically incorporation into oligonucleotides Sarah Krüger, Chris Meier Nucleic Acids Symposium Series 52, 307-308 (2008) |
| 154 |
Oligonucleotides damaged with carcinogenic aromatic amines at the C8- and N6-position of 2'-deoxyadenosine Maike I. Jacobsen, Chris Meier Nucleic Acids Symposium Series 52, 439-440 (2008) |
| 153 |
Improved synthesis of nucleoside diphosphate glycopyranoses Tanja Zismann, Chris Meier Nucleic Acids Symposium Series 52, 563-564 (2008) |
| 152 |
New efficient synthesis of nucleoside diphosphate glycopyranoses Saskia Wolf, Chris Meier Nucleic Acids Symposium Series 52, 579-580 (2008) |
| 151 |
New and efficient synthesis of nucleoside polyphosphates and nucleoside monophosphate sugars Svenja Warnecke, Chris Meier Nucleic Acids Symposium Series 52, 583-584 (2008) |
| 150 |
Carbocyclic L-nucleoside analogs as potential antiviral agents Sönke Jessel, Chris Meier Nucleic Acids Symposium Series 52, 615-616 (2008) |
| 149 |
The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase Sabine Specht, Salem Ramadan Sarite, Ilona Hauber, Joachim Hauber, Ulf Görbig, Chris Meier , Dorian Bevec, Achim Hoerauf, Annette Kaiser Parasitology Research 102, 1177-1184 (2008) |
| 148 |
First route to phosphoramidites of N2-hydrazinoaryl- and N2-azoaryl-dG adducts and their site-selective incorporation into DNA oligonucleotides Nicolas Böge, Marcus Schröder, Chris Meier Synlett 1066-1070 (2008) |
| 147 |
Synthesis of N2- and C8-N-Ac-DNA-adducts of aromatic amines Nicolas Böge, Sarah Krüger, Chris Meier Collection of Czechoslovak Chemical Communications, Collection Symposium Series 10, 137-141 (2008) |
2007 | |
| 146 |
Properties of Aminoacid Esters Linked to cycloSal-Pronucleotides Henning Jacob Jessen, Jan Balzarini, Chris Meier Antiviral Research 74, A73-A73 (2007) |
| 145 |
Bis-cycloSal-d4T-monophosphates: Drugs That Deliver Two Molecules of Bioactive Nucleotides Christian Ducho, Ulf Görbig, Sönke Jessel, Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 50, 1335-1346 (2007) |
| 144 |
Enzymatically Activated cycloSal-d4T-monophosphates: The Third Generation of cycloSal-Pronucleotides Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 50, 1658-1667 (2007) |
| 143 |
Synthesis of DNA-Oligonucleotides Damaged by Arylamine-Modified 2'-Deoxyguanosine Nicolas Böge, Zita Szombati, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 705-708 (2007) |
| 142 |
Intracellular Trapping of cycloSal-Pronucleotides by Enzymatic Cleavage Henning Jacob Jessen, Viktoria Caroline Tonn, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 827-830 (2007) |
| 141 |
New cycloAMB-Nucleoside Phosphonate Prodrugs Ulf Görbig, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 831-834 (2007) |
| 140 |
5-Diacetoxymethyl-cycloSal-d4TMP - A prototype of enzymatically activated cycloSal-pronucleotides Nicolas Gisch, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 861-864 (2007) |
| 139 |
A New and Short Convergent Synthetic Strategy to Carbocyclic Nucleosides Bastian Reichardt, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 935-937 (2007) |
| 138 |
Cyclopentane-Nucleobase
Coupling in the Synthesis of Carbocyclic L-Nucleosides: is A SN2-Reaction an Alternative to the Mitsunobu-Reaction? Sönke Jessel, Elena Hense, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 1181-1184 (2007) |
| 137 |
Synthesis of C8-Modified 2'-Deoxyadenosine with Carcinogenic Arylamines Maike I. Jacobsen, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 1217-1220 (2007) |
| 136 |
New Developments of the "Lock-in" Modified cycloSal-d4TMPs Dalibor Vukadinovic-Tenter, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 1325-1328 (2007) |
| 135 |
A new short and efficient synthetic route to C8-N-acetylarylamine 2'-deoxyguanosine phosphoramidites Nicolas Böge, Sarah Krüger, Marcus Schröder, Chris Meier Synthesis 3907-3914 (2007) |
2006 | |
| 134 |
Inhibitory efficacy of cycloSal-nucleoside monophosphates of aciclovir and brivudin on DNA synthesis of orthopoxviruses Andreas Sauerbrei, Chris Meier , Astrid Meerbach, Peter Wutzler Antiviral Chemistry & Chemotherapy 17, 25-31 (2006) |
| 133 |
Stereoselective Synthesis and Biological Evaluation of D- and L-carba-Nucleosides as Potential Antiviral Agents Chris Meier , Sönke Jessel, Bastian Reichardt, Olaf Rudolf Ludek, Jan Balzarini Antiviral Research 70, A27 (2006) |
| 132 |
cycloSal-Monophosphate Prodrugs with an Optimized Mask Ulf Görbig, Anne Baum, Jan Balzarini, Chris Meier Antiviral Research 70, A60 (2006) |
| 131 |
Enzymatically Activated cycloSal-Pronucleotides Nicolas Gisch, Jan Balzarini, Chris Meier Antiviral Research 70, A60 (2006) |
| 130 |
Synthesis and Properties of Intrinsically Fluorescent cycloSal-Pronucleotides Henning Jacob Jessen, Wolfgang Fendrich, Tilmann Schulz, Jan Balzarini, Chris Meier Antiviral Research 70, A60 (2006) |
| 129 |
Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules Chris Meier , Jan Balzarini Antiviral Research 71, 282-292 (2006) |
| 128 |
New and efficient synthesis of racemic cyclopent-3-en-1-yl nucleoside analogues and their derivatives Bastian Reichardt, Olaf Rudolf Ludek, Chris Meier Collection of Czechoslovak Chemical Communications 71, 1011-1028 (2006) |
| 127 |
Second-generation cycloSal-d4TMP pronucleotides bearing esterase-cleavable sites - the "trapping" concept Chris Meier , Christian Ducho, Henning Jacob Jessen, Dalibor Vukadinovic-Tenter, Jan Balzarini European Journal of Organic Chemistry 197-206 (2006) |
| 126 |
Synthesis and properties of fluorescent cycloSal nucleotides m5K and its 2',3'-dideoxy analog dm5K Henning Jacob Jessen, Wolfgang Fendrich, Chris Meier European Journal of Organic Chemistry 924-931 (2006) |
| 125 |
Synthesis and antiviral evaluation of carbocyclic 3'-azidothymidine (AZT) analogs and their cycloSal-phosphate triesters Olaf Rudolf Ludek, Jan Balzarini, Chris Meier European Journal of Organic Chemistry 932-940 (2006) |
| 124 |
Influence of the N3-protection group on N1- vs. O2-alkylation in the Mitsunobu reaction Olaf Rudolf Ludek, Chris Meier European Journal of Organic Chemistry 941-946 (2006) |
| 123 |
cycloSal phosphates as chemical Trojan horses for intracellular nucleotide and glycosyl-monophosphate delivery - chemistry meets biology Chris Meier European Journal of Organic Chemistry 1081-1102 (2006) |
| 122 |
Antiviral activity of cycloSaligenyl prodrugs of the nucleoside analogue bromovinyldeoxyuridine against herpes viruses Astrid Meerbach, Chris Meier , Andreas Sauerbrei, Heide-Marie Meckel, Peter Wutzler International Journal of Antimicrobial Agents 27, 423-430 (2006) |
| 121 |
Synthesis and Properties of Oligonucleotides Containing C8-Deoxyguanosine Arylamine Adducts of Borderline Carcinogens Nicolas Böge, Sonja Gräsl, Chris Meier Journal of Organic Chemistry 71, 9728-9738 (2006) |
| 120 |
Study of the efficacy of a pronucleotide of 2-chloro-2'-deoxyadenosine in deoxycytidine kinase-deficient lymphoma cells Françoise Bontemps, Chris Meier , Anne Delacauw, Jan Balzarini, Carlos M. Galmarini, Eric van den Neste Nucleosides, Nucleotides & Nucleic Acids 25, 997-1000 (2006) |
| 119 |
Synthesis of carbocyclic pyrimidine nucleosides using the Mitsunobu reaction - part II: influence of the solvent on N1- versus O2-alkylation Olaf Rudolf Ludek, Chris Meier Synlett 324-326 (2006) |
| 118 |
First synthesis of C8-arylamine adducts of 2'-deoxyadenosine and incorporation of the phosphoramidite into an oligonucleotide Maike I. Jacobsen, Chris Meier Synlett 2411-2414 (2006) |
| 117 |
Divergent synthesis and biological evaluation of carbocyclic α-, iso- and 3'-epi-nucleosides and their lipophilic nucleotide prodrugs Olaf Rudolf Ludek, Tobias Krämer, Jan Balzarini, Chris Meier Synthesis 1313-1324 (2006) |
| 116 |
Department für Chemie. Fakultät für Mathematik, Informatik und Naturwissenschaften. Chemiedozententagung 2006 Chris Meier , Jürgen Heck, Wilhelm Herdering, Thomas Behrens -/- Herausgeber: Universität Hamburg |
| 115 |
The cycloSal-Nucleotide Delivery System - Development of Chemical Trojan Horses as Antiviral Agents Chris Meier -/- Herausgeber: Godefridus J. Peters Deoxynucleoside Analogs in Cancer Chemotherapy 353-401 (2006) |
2005 | |
| 114 |
A Possible Synthetic Strategy to Diastereomerically Pure cycloSal-Prodrugs Jens Oliver Thomann, Katharina Wallach, Edwuin Hander Rios Morales, Chris Meier Antiviral Research 65, A93 (2005) |
| 113 |
Novel "Lock-in" Modified cycloSal Nucleotides (I): Variations of the Linker Moiety Dalibor Vukadinovic, Chris Meier , Jan Balzarini Antiviral Research 65, A93 (2005) |
| 112 |
cycloAmb Nucleoside Phosphonates: Nucleoside Phosphonate Prodrugs Based on the cycloSal Concept Ulf Görbig, Jan Balzarini, Chris Meier Antiviral Research 65, A94 (2005) |
| 111 |
In vitro activity of cycloSal-nucleoside monophosphates and polyhydroxycarboxylates against orthopoxviruses Andreas Sauerbrei, Chris Meier , Astrid Meerbach, M. Schiel, Björn Helbig, Peter Wutzler Antiviral Research 67, 147-154 (2005) |
| 110 |
Antivirale Aktivität von Phenolkörperpolymerisaten und cycloSaligenyl-Pronucleotiden gegen ein SARS-assoziiertes Coronavirus (Antiviral activity of phenolic polymers and cycloSaligenyl-pronucleotides towards SARS-related Coronavirus) Michaela Schmidtke, Chris Meier , Michael Schacke, Björn Helbig, Vadim Makarov, Holger F. Rabenau, Jindrich Cinatl Jr., Peter Wutzler Chemotherapie Journal 14 (1) 16-21 (2005) |
| 109 |
cycloSal-pronucleotides of brivudine monophosphate - highly active antiviral agents Chris Meier , Astrid Meerbach, Peter Wutzler Current Medicinal Chemistry: Anti-Infective Agents 4, 317-335 (2005) |
| 108 |
cycloSal-PMEA and cycloAmb-PMEA: Potentially New Phosphonate Prodrugs Based on the cycloSal-Pronucleotide Approach Chris Meier , Ulf Görbig, Hanns Christian Müller, Jan Balzarini Journal of Medicinal Chemistry 48, 8079-8086 (2005) |
| 107 |
Novel cycloSal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase Christian Ducho, Sönke Jessel, Nicolas Gisch, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 24, 519-522 (2005) |
| 106 |
Synthesis of carbocyclic nucleotides as potential substrates for thymidylate kinase Olaf Rudolf Ludek, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 24, 683-686 (2005) |
| 105 |
Synthesis of oligonucleotides bearing an arylamine modification in the C8-position of 2'-deoxyguanosine Chris Meier , Sonja Gräsl, Ilka Detmer, Andreas Marx Nucleosides, Nucleotides & Nucleic Acids 24, 691-694 (2005) |
| 104 |
"Lock-in" modified cycloSal nucleotides - the second generation of cycloSal prodrugs Dalibor Vukadinovic, Nicolas Böge, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 24, 939-942 (2005) |
| 103 |
Synthesis of carbocyclic pyrimidine nucleosides using the Mitsunobu reaction - part I: influence of the alcohol on N1- versus O2-alkylation. Olaf Rudolf Ludek, Chris Meier Synlett 3145-3147 (2005) |
| 102 |
Esterase-cleavable cycloSal-pronucleotides - the trapping concept Chris Meier , Christian Ducho, Henning Jacob Jessen, Jan Balzarini Collection of Czechoslovak Chemical Communications, Collection Symposium Series 7, 105-113 (2005) |
2004 | |
| 101 |
Are Cholinesterases Inhibited by cycloSal-Nucleotides? Chris Meier , Christian Ducho, Jan Balzarini Antiviral Research 62, A85 (2004) |
| 100 |
cycloSaligenyl-mannose-1-monophosphates as a new strategy in CDG-Ia therapy: hydrolysis, mechanistic insights and biological activity Ulrike Muus, Christian Kranz, Thorsten Marquardt, Chris Meier European Journal of Organic Chemistry 1228-1235 (2004) |
| 99 |
cycloSal-pronucleotides - development of first and second generation chemical Trojan horses for antiviral chemotherapy Chris Meier , Astrid Meerbach, Jan Balzarini Frontiers in Bioscience 9, 873-890 (2004) |
| 98 |
Interaction of cycloSal-Pronucleotides with Cholinesterases from Different Origins. A Structure-Activity Relationship Chris Meier , Christian Ducho, Ulf Görbig, Robert Esnouf, Jan Balzarini Journal of Medicinal Chemistry 47, 2839-2852 (2004) |
| 97 |
"Lock-in"-cycloSal-pronucleotides - a new generation of chemical Trojan horses? Chris Meier , Manuel F. H. Ruppel, Dalibor Vukadinovic, Jan Balzarini Mini-Reviews in Medicinal Chemistry 4, 383-394 (2004) |
| 96 |
Second Generation of cycloSal-Pronucleotides with Esterase-Cleavable Sites: The "Lock-In"-Concept Chris Meier , Manuel F. H. Ruppel, Dalibor Vukadinovic, Jan Balzarini Nucleosides, Nucleotides & Nucleic Acids 23, 89-115 (2004) |
| 95 |
cycloSal-pronucleotides-design of the concept, chemistry, and antiviral activity Chris Meier -/- Herausgeber: Erik de Clercq Advances in Antiviral Drug Design 4, 147-213 (2004) |
2003 | |
| 94 |
"Lock-in"-Modified cycloSal-d4TMP and -BVdUMP Triesters - Extention of a Pronucleotide System Chris Meier , Manuel F. H. Ruppel, Dalibor Vukadinovic, Astrid Meerbach, Peter Wutzler, Erik de Clercq, Jan Balzarini Antiviral Research 57, A39 (2003) |
| 93 |
A Short and Efficient Route Towards Enantiomerically Pure Carbocyclic Analogues of Thymidine: New Substrates for Thymidylate Kinase? Olaf Rudolf Ludek, Jan Balzarini, Chris Meier Antiviral Research 57, A54 (2003) |
| 92 |
Interaction of Cholinesterases with cycloSal-Nucleotides Christian Ducho, Jan Balzarini, Chris Meier Antiviral Research 57, A54 (2003) |
| 91 |
Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy Cristina Mazzon, Chiara Rampazzo, Maria Chiara Scaini, Lisa Gallinaro, Anna Karlsson, Chris Meier , Jan Balzarini, Peter Reichard, Vera Bianchi Biochemical Pharmacology 66, 471-479 (2003) |
| 90 |
Structures of Human Thymidylate Kinase in Complex with Prodrugs: Implications for the Structure-Based Design of Novel Compounds Nils Ostermann, Dario Segura-Peña, Chris Meier , Thomas Veit, Christian Monnerjahn, Manfred Konrad, Arnon Lavie Biochemistry 42, 2568-2577 (2003) |
| 89 |
Antiviral effects of cycloSaligenyl-pronucleotides towards Herpes simplex virus and Epstein-Barr virus Astrid Meerbach, Renate Klöcking, Claudia Friedrichs, Peter Wutzler, Chris Meier Chemotherapie Journal 12 (3) 79-84 (2003) |
| 88 |
3,5-Di-(tert-butyl)-6-fluoro-cycloSal-d4TMP - a pronucleotide with a considerably improved masking group Christian Ducho, Silke Wendicke, Ulf Görbig, Jan Balzarini, Chris Meier European Journal of Organic Chemistry 4786-4791 (2003) |
| 87 |
Synthesis of Carbocyclic Analogues of Thymidine Olaf Rudolf Ludek, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 683-685 (2003) |
| 86 |
Study of Different Substituted Cyclic and Acyclic Benzylpronucleotides of d4T Relative to Their Hydrolytic Stability and Antiviral Activity Ulrike Muus, Erik de Clercq, Jan Balzarini, Lieve Naesens, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 791-795 (2003) |
| 85 |
Novel Nucleotide Analogues as Potential Substrates for TMPK, a Key Enzyme in the Metabolism of AZT Hanns Christian Müller, Chris Meier , Jan Balzarini, Jochen Reinstein Nucleosides, Nucleotides & Nucleic Acids 22, 821-823 (2003) |
| 84 |
d4TMP Delivery from 7-Substituted cycloSal-d4TMPs Chris Meier , Jürgen Renze, Jan Balzarini, Erik de Clercq Nucleosides, Nucleotides & Nucleic Acids 22, 825-827 (2003) |
| 83 |
Non-inhibition of acetylcholinesterase by cycloSal nucleotides Christian Ducho, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 841-843 (2003) |
| 82 |
Synthesis of Oligonucleotide Building Blocks of 2'-Deoxyguanosine Bearing a C8-Arylamine Modification Sonja Gräsl, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 1119-1121 (2003) |
| 81 |
α-Hydroxybenzylphosphonate Modified Oligonucleotides: Synthesis, Properties, and a Novel Route via Monomer Building Blocks Andreas Hohlfeld, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 1123-1125 (2003) |
| 80 |
Determination of the Absolute P-Configuration of a Phthalidyl-Phosphonate Thymidine-Thymidine Dimer Wolfgang Fendrich, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 1127-1129 (2003) |
| 79 |
New convergent synthesis of carbocyclic nucleoside analogues Olaf Rudolf Ludek, Chris Meier Synthesis 2101-2109 (2003) |
2002 | |
| 78 |
Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cycloSal-d4TMP - hydrolysis, mechanistic insights and anti-HIV activity Chris Meier , Ulrike Muus, Jürgen Renze, Lieve Naesens, Erik de Clercq, Jan Balzarini Antiviral Chemistry & Chemotherapy 13, 101-114 (2002) |
| 77 |
Aryl-substituted and benzo-annulated cycloSal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate - correlation of structure, hydrolysis properties and anti-HIV activity Christian Ducho, Jan Balzarini, Lieve Naesens, Erik de Clercq, Chris Meier Antiviral Chemistry & Chemotherapy 13, 129-141 (2002) |
| 76 |
Comparative Study of Different Benzyl-Pronucleotides of d4T: Hydrolytic Stability and Antiviral Activity Ulrike Muus, Chris Meier , Lieve Naesens, Erik de Clercq, Jan Balzarini Antiviral Research 53, A37 (2002) |
| 75 |
cycloSal-d4TMP pronucleotides-structural variations, mechanistic insights and antiviral activity Chris Meier , Jürgen Renze, Christian Ducho, Jan Balzarini Current Topics in Medicinal Chemistry 2, 1111-1121 (2002) |
| 74 |
cycloSal-BVDUMP Pronucleotides: How to Convert an Antiviral-Inactive Nucleoside Analogue into a Bioactive Compound against EBV Chris Meier , Andreas Lomp, Astrid Meerbach, Peter Wutzler Journal of Medicinal Chemistry 45, 5157-5172 (2002) |
| 73 |
cycloSal-pronucleotides - design of chemical Trojan horses Chris Meier Mini-Reviews in Medicinal Chemistry 2, 219-234 (2002) |
| 72 |
Formation of benzooxaphosphole oxide heterocyclic system by the ring-contractive Arbuzov-Michaelis isomerization of alkoxy-substituted benzodioxaphosphorins Eduard E. Nifantiev, Svetlana B. Khrebtova, Yulia V. Kulikova, Dmitrii A. Predvoditelev, Tat'yana S. Kukhareva, Pavel V. Petrovskii, Mirjam Rose, Chris Meier Phosphorus, Sulfur and Silicon and the Related Elements 177, 251-259 (2002) |
| 71 |
Highly efficient synthesis of a phosphoramidite building block of C8-deoxyguanosine adducts of aromatic amines Chris Meier , Sonja Gräsl Synlett 802-804 (2002) |
2001 | |
| 70 |
Antiviral activity of cycloSaligenyl prodrugs of acyclovir, carbovir, and abacavir Jan Balzarini, Friederike Haller-Meier, Erik de Clercq, Chris Meier Antiviral Chemistry & Chemotherapy 12, 301-306 (2001) |
| 69 |
Novel Synthetic Route Towards Cyclic and Acyclic Analogues of AZT Monophosphate (AZTMP) Hanns Christian Müller, Chris Meier , Erik de Clercq, Jan Balzarini, Jochen Reinstein Antiviral Research 50, A46 (2001) |
| 68 |
Hydrolysis Behavior of Benzyl-Functionalized cycloSal-d4TMPs Jürgen Renze, Chris Meier , Jan Balzarini, Erik de Clercq Antiviral Research 50, A47 (2001) |
| 67 |
cycloSal-BVDUMP Triesters - Synthesis, Properties and Anti-EBV Activity of New Potential Pronucleotides Chris Meier , Andreas Lomp, Astrid Meerbach, Peter Wutzler Antiviral Research 50, A60 (2001) |
| 66 |
cycloSaligenyl-5-[(E)-2-bromovinyl]-2'-deoxyuridine monophosphate (cycloSal-BVDUMP) pronucleotides active against Epstein-Barr virus Chris Meier , Andreas Lomp, Astrid Meerbach, Peter Wutzler ChemBioChem 2, 283-285 (2001) |
| 65 |
Synthesis, hydrolysis and anti-EBV activity of a series of 3'-modified cycloSal-BVDUMP pronucleotides Chris Meier , Andreas Lomp, Astrid Meerbach, Peter Wutzler Nucleosides, Nucleotides & Nucleic Acids 20, 307-314 (2001) |
| 64 |
Benzyl-functionalized cycloSal-d4T monophosphates Jürgen Renze, M. Plath, Christian Ducho, Jan Balzarini, Erik de Clercq, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 20, 931-934 (2001) |
2000 | |
| 63 |
Inhibitory Effect of cycloSaligenyl-Nucleoside Monophosphates of Acyclic Nucleoside Analogues on HSV-1 and EBV Astrid Meerbach, Renate Klöcking, Chris Meier , Andreas Lomp, Björn Helbig, Peter Wutzler Antiviral Research 45, 69-77 (2000) |
| 62 |
Intracellular Metabolism of 3-Methyl-cycloSal-d4TMP and 3-Methyl-cycloSal-AZTMP: Same Concept but Different Antiviral Outcome Jan Balzarini, Tina Knispel, Lieve Naesens, Erik de Clercq, Chris Meier Antiviral Research 46, A46 (2000) |
| 61 |
Synthesis, Properties and Anti-EBV Activity of a New Series of 3'-Modified cycloSal-BVDUMP Pronucleotides Astrid Meerbach, Peter Wutzler, Andreas Lomp, Chris Meier Antiviral Research 46, A82 (2000) |
| 60 |
Interactions of Conformationally Biased North and South 2'-Fluoro-2',3'-dideoxynucleoside 5'-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase Lan Mu, Stefan G. Sarafianos, Marc C. Nicklaus, Pamela Russ, Maqbool A. Siddiqui, Harry Ford, Hiroaki Mitsuya, Richard Le, Eiichi Kodama, Chris Meier , Tina Knispel, Lynne Anderson, Joseph J. Barchi, Victor E. Marquez Biochemistry 39, 11205-11215 (2000) |
| 59 |
cycloSaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP Jan Balzarini, Stefano Aquaro, Tina Knispel, Chiara Rampazzo, Vera Bianchi, Carlo-Federico Perno, Erik de Clercq, Chris Meier Molecular Pharmacology 58, 928-935 (2000) |
| 58 |
Structures of Human Thymidylate Kinase in Complex with Nucleotides Nils Ostermann, Amon Lavie, Sreekanta Padiyar, Ralf Brundiers, Manfred Konrad, Axel Scheidig, Chris Meier , Jochen Reinstein, Thomas Veit, Roger Goody, Ilme Schlichting Hamburger Synchrotonstrahlungslabor HASYLAB am Deutschen Elektronen-Synchroton DESY. Jahresbericht 1999 II, 295-296 (2000) Alternativer Quellentitel: HASYLAB Annual Report |
| 57 |
Methylphosphonic acid esters, processes for their preparation, and their use Eugen Uhlmann, Chris Meier -/- Anmelder: Hoechst AG Patent: US 6028182 (A) 2000-02-22 |
1999 | |
| 56 |
cycloSal-Pronucleotides of 2',3'-Dideoxyadenosine and 2',3'-Dideoxy-2',3'-didehydroadenosine: Synthesis and Antiviral Evaluation of a Highly Efficient Nucleotide Delivery System Chris Meier , Tina Knispel, Erik de Clercq, Jan Balzarini Journal of Medicinal Chemistry 42, 1604-1614 (1999) |
| 55 |
cycloSal-Pronucleotides of 2'-Fluoro-ara- and 2'-Fluoro-ribo-2',3'-dideoxyadenosine as a Strategy to Bypass a Metabolic Blockade Chris Meier , Tina Knispel, Victor E. Marquez, Maqbool A. Siddiqui, Erik de Clercq, Jan Balzarini Journal of Medicinal Chemistry 42, 1615-1624 (1999) |
| 54 |
Intracellular Metabolism of cycloSaligenyl 3'-Azido-2',3'-dideoxythymidine Monophosphate, a Prodrug of 3'-Azido-2',3'-dideoxythymidine (Zidovudine) Jan Balzarini, Lieve Naesens, Stefano Aquaro, Tina Knispel, Carlo-Federico Perno, Erik de Clercq, Chris Meier Molecular Pharmacology 56, 1354-1361 (1999) |
| 53 |
cycloSal-2'-ara(ribo)-fluoro-2',3'-dideoxyadenosine monophosphates - an effort to solve the structure-activity relationship of 2'-fluoro-ddA Chris Meier , Tina Knispel, Victor E. Marquez, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 18, 907-912 (1999) |
| 52 |
Effects of cycloSal-d4TMP-Derivatives in H9 Cells with Induced AZT Resistanance Phenotype Bettina Gröschel, Chris Meier , Richard Zehner, J. Cinatl, Hans W. Doerr, J. Cinatl Jr. Nucleosides & Nucleotides 18, 933-936 (1999) |
| 51 |
Phosphoramidite chemistry for the synthesis of cycloSal-pronucleotides Florence Mugnier, Chris Meier Nucleosides & Nucleotides 18, 941-942 (1999) |
| 50 |
Evidence for cyclophosphate formation during hydrolysis of 3-methyl-cycloSal-PCVMP Andreas Lomp, Chris Meier , Markus Herderich, Peter Wutzler Nucleosides & Nucleotides 18, 943-944 (1999) |
| 49 |
N,O-selectivity in the synthesis of 3-Me-cycloSal-ddAMP Tina Knispel, Chris Meier Nucleosides & Nucleotides 18, 945-946 (1999) |
| 48 |
A new cyclic phosphoramidate d4T prodrug approach cycloAmb-d4T-phosphoramidates Martina Lorey, Chris Meier Nucleosides & Nucleotides 18, 947-948 (1999) |
| 47 |
Elucidation of the hydrolytical properties of α-hydroxybenzylphosphonates as a new potential prooligonucleotide concept Ralf Peter Mauritz, Frank S. Schmelz, Chris Meier Nucleosides & Nucleotides 18, 1417-1418 (1999) |
1998 | |
| 46 |
Synthesis and Antiviral Evaluation of SATE-Foscarnet Prodrugs and New Foscarnet-AZT Conjugates Chris Meier , Anne-Marie Aubertin, M. de Monte, A. Faraj, Jean-Pierre Sommadoussi, Christian Perigaud, Jean-Louis Imbach, Gilles Gosselin Antiviral Chemistry & Chemotherapy 9, 41-51 (1998) |
| 45 |
Chemistry and Anti-Herpes SimplexVirus Type 1 Evaluation of cycloSal-Nucleotides of Acyclic Nucleoside Analogues Chris Meier , Lothar W. Habel, Friederike Haller-Meier, Andreas Lomp, Markus Herderich, Renate Klöcking, Astrid Meerbach, Peter Wutzler Antiviral Chemistry & Chemotherapy 9, 389-402 (1998) |
| 44 |
cycloSal-Nucleotides of 2',3'-Dideoxyadenosine Derivatives as Efficient Nucleotide Delivery Systems Chris Meier , Tina Knispel, Victor E. Marquez, Erik de Clercq, Jan Balzarini Antiviral Research 37, A63 (1998) |
| 43 |
Chemistry and Properties of cycloSaligenyl-Nucleotides (cycloSal-NMP) of Acyclic Nucleoside Analogues as Potential Anti-HSV Agents Chris Meier , Lothar W. Habel, Friedericke Meier, Peter Wutzler Antiviral Research 37, A75 (1998) |
| 42 |
Inhibitory Effect of cycloSaligenyl-Nucleoside Monophosphates (cycloSal-NMP) of Acyclic Nucleoside Analogues on HSV-1 and EBV Astrid Meerbach, Renate Klöcking, Chris Meier , Peter Wutzler Antiviral Research 37, A76 (1998) |
| 41 |
Nucleotide delivery from cycloSaligenyl-3'-azido-3'-deoxythymidine monophosphates (cycloSal-AZTMP) Chris Meier , Erik de Clercq, Jan Balzarini European Journal of Organic Chemistry 837-846 (1998) |
| 40 |
cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine Monophosphate (cycloSal-d4TMP): Synthesis and Antiviral Evaluation of a New d4TMP Delivery System Chris Meier , Martina Lorey, Erik de Clercq, Jan Balzarini Journal of Medicinal Chemistry 41, 1417-1427 (1998) |
| 39 |
Pronucleotides - Recent Advances in the Design of Efficient Tools for the Delivery of Biologically Active Nucleoside Monophosphates (Review) Chris Meier Synlett 233-242 (1998) |
1997 | |
| 38 |
Cyclic saligenyl phosphotriesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T). A new pronucleotide approach Chris Meier , Martina Lorey, Erik de Clercq, Jan Balzarini Bioorganic & Medicinal Chemistry Letters 7, 99-104 (1997) |
| 37 |
ADA-bypass by lipophilic cycloSal-ddAMP pronucleotides a second example of the efficiency of the cycloSal-concept Chris Meier , Tina Knispel, Erik de Clercq, Jan Balzarini Bioorganic & Medicinal Chemistry Letters 7, 1577-1582 (1997) |
| 36 |
Auf dem Weg zu neuen, nicht-enzymatisch spaltbaren Pro-Nucleotiden - Ziel ist, selektiv in den Proliferationszyklus der Viren einzugreifen (Towards new, non-enzymically cleavable pronucleotides) Chris Meier , Martina Lorey, Tina Knispel GIT Labor-Fachzeitschrift 41, 965-967 (1997) |
| 35 |
cycloSal-Pronucleotides: Design and Biological Evaluation of a New Class of Lipophilic Nucleotide Prodrugs Chris Meier , Tina Knispel, Martina Lorey, Jan Balzarini International Antiviral News 5, 183-185 (1997) |
| 34 |
Fpmp-protected α-hydroxyphosphonate diesters for the synthesis of prooligonucleotides Ralf Peter Mauritz, Chris Meier Nucleosides & Nucleotides 16, 675-678 (1997) |
| 33 |
New synthesis and antitumor activity of cycloSal-derivatives of 5-fluoro-2'-deoxyuridinemonophosphate Martina Lorey, Chris Meier , Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 789-792 (1997) |
| 32 |
cycloSaligenyl-3'-azido-2',3'-dideoxythymidine monophosphate (cycloSal-AZTMP) - a new pronucleotide approach? Chris Meier , Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 793-796 (1997) |
| 31 |
Synthesis of 3',5'-dithymidylyl-α-hydroxyphosphonate dimer building blocks for oligonucleotide synthesis - a new prooligonucleotide approach - Ralf Peter Mauritz, Chris Meier , Eugen Uhlmann Nucleosides & Nucleotides 16, 1209-1212 (1997) |
| 30 |
cycloSaligenyl-2',3'-dideoxy-2',3'-didehydroythymidinemonophosphate (cycloSal-D4TMP) - a new pronucleotide approach -. Chris Meier , Martina Lorey, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 1303-1306 (1997) |
| 29 |
cycloSaligenyl-5-fluoro-2'-deoxyuridinemonophosphate (cycloSal-FDUMP) - a new prodrug approach for FDUMP Martina Lorey, Chris Meier , Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 1307-1310 (1997) |
| 28 |
Di-ddU-α-hydroxyphosphonate and α-hydroxy-α-methylphosphonates as potential prodrugs of antiviral nucleoside analogs Lothar W. Habel, Chris Meier Nucleosides & Nucleotides 16, 1311-1314 (1997) |
| 27 |
Fast-atom bombardment mass spectrometric study of SATE Foscarnet prodrugs and of a series of Foscarnet-AZT conjugates Jef Rozenski, Chris Meier , Jean-Louis Aubagnac, Rene Astier, Piet Herdewijn, Jean-Louis Imbach, Gilles Gosselin Rapid Communications in Mass Spectrometry 11, 1212-1218 (1997) |
1996 | |
| 26 |
2-Nucleos-5'-O-yl-4H-1,3,2-benzodioxaphosphinin-2-oxides: A new concept for lipophilic, potential prodrugs of biologically active nucleoside monophosphates Chris Meier Angewandte Chemie, International Edition in English 35, 70-72 (1996) Translated: Angewandte Chemie 108, 77-796 (1996) |
| 25 |
2-Nucleosyl-4H-1,3,2-benzodioxophosphorine-2-oxides. A new concept for lipophilic prodrugs of biologically active nucleoside monophosphates Chris Meier , Martina Lorey, Erik de Clercq, Jan Balzarini Antiviral Research 30, A29-A29 (Poster 37) (1996) Alternativer Quellentitel: The Ninth International Conference on Antiviral Research, 19-24 May 1996, Urabandai Nekoma Hotel Urabandai, Fukushima, Japan, Abstract 37 (1996) |
| 24 |
Enantioselective synthesis of diisopropyl α-, β-, and γ-hydroxyarylalkylphosphonates from ketophosphonates: a study on the effect of the phosphonyl group Chris Meier , Wolfgang Hans Gerhardt Laux Tetrahedron 52, 589-598 (1996) |
| 23 |
Asymmetric synthesis of chiral, nonracemic dialkyl-.alpha.-hydroxyalkylphosphonates via a (-)-chlorodiisopinocampheylborane (Ipc2B-Cl) reduction Chris Meier , Wolfgang Hans Gerhardt Laux Tetrahedron: Asymmetry 7, 89-94 (1996) |
| 22 |
Auf dem Weg zu neuen Prodrugs für antiviral aktive Nucleotide und Oligonucleotide sowie zu chiralen, nichtracemischen α-Hydroxyphosphonat-Enzyminhibitoren Chris Meier Habilitationsschrift, Frankfurt (1996) |
1995 | |
| 21 |
Direct mass-spectrometric sequencing of low-picomole amounts of oligodeoxynucleotides with up to 21 bases by matrix-assisted laser-desorption ionization mass-spectrometry Eckhard Nordhoff, Michael Karas, Rainer Cramer, Stephanie Hahner, Franz Hillenkamp, Finn Kirpekar, Axel Lezius, Jochen Muth, Chris Meier , Joachim W. Engels Journal of Mass Spectrometry 30, 99-112 (1995) |
| 20 |
Asymmetric synthesis of chiral, nonracemic dialkyl α-hydroxyarylmethyl- and α-, β-, and γ-hydroxyalkylphosphonates from keto phosphonates Chris Meier , Wolfgang Hans Gerhardt Laux, Jan W. Bats Liebigs Annalen 1963-1979 (1995) |
| 19 |
Lipophilic α-hydroxybenzylphosphonates as prodrugs of 3'-azido-2',3'-dideoxythymidine (AZT) Chris Meier , Lothar W. Habel, Jan Balzarini, Erik de Clercq Liebigs Annalen 2195-2202 (1995) |
| 18 |
5',5'-Di-O-nucleosyl-O'-benzylphosphotriesters as potential prodrugs of 3'-azido-2',3'-dideoxythymidine-5'-monophosphate Chris Meier , Lothar W. Habel, Jan Balzarini, Erik de Clercq Liebigs Annalen 2203-2208 (1995) |
| 17 |
Homo dinucleoside-α-hydroxyphosphonate diesters as prodrugs of the antiviral nucleoside analogs 2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine Chris Meier , Lothar W. Habel, Wolfgang Hans Gerhardt Laux, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 14, 759-762 (1995) |
| 16 |
Synthesis of protected 3',5'-di-2'-deoxythymidine-(α-hydroxy-2-nitrobenzyl)-phosphonate diesters as dimer building blocks for oligonucleotides Chris Meier , Ralf Peter Mauritz Nucleosides & Nucleotides 14, 803-804 (1995) |
| 15 |
Asymmetric synthesis of chiral, nonracemic dialkyl-α-, β-, and γ-hydroxyalkylphosphonates via a catalyzed enantioselective catecholborane reduction. Chris Meier , Wolfgang Hans Gerhardt Laux Tetrahedron: Asymmetry 6, 1089-1092 (1995) |
| 14 |
Preparation of (arylhydroxymethyl)phosphonate esters of nucleoside analogs and related compounds as drugs Eugen Uhlmann, Chris Meier -/- Anmelder: Hoechst AG Patent: DE 4321946 (A1) 1995-01-12 |
1993 | |
| 13 |
5',5'-O-Dinucleoside (α-hydroxybenzyl)phosphonates as a lipophilic potential prodrugs of 2',3'-dideoxythymidine (ddT) Chris Meier Angewandte Chemie, International Edition in English 32, 1704-1706 (1993) Translated: Angewandte Chemie 105, 1854-1856 (1993) |
1992 | |
| 12 |
Peptide nucleic acids (PNA's): unusual properties of a nonionic oligonucleotide analog Chris Meier , Joachim W. Engels Angewandte Chemie, International Edition in English 31, 1008-1010 (1992) Translated: Angewandte Chemie 104, 1039-1041 (1992) |
| 11 |
O-Alkyl-5',5'-dinucleoside phosphates as prodrugs of 3'-azidothymidine and cordycepin Chris Meier , Jean Michel Neumann, Francois André, Yvette Henin, Huynh-Dinh Tam Journal of Organic Chemistry 57, 7300-7308 (1992) |
1991 | |
| 10 |
O-Alkyl-5',5'-dinucleoside phosphates as combined prodrugs of antiviral and antibiotic compounds Chris Meier , Huynh-Dinh Tam Bioorganic & Medicinal Chemistry Letters 1, 527-530 (1991) |
| 9 |
The modification of guanine nucleosides and nucleotides by the borderline arylamine carcinogens 4-methyl- and 4-methoxyaniline: chemistry and structural characterization Chris Meier , Gernot Boche Carcinogenesis 12, 1633-1640 (1991) |
| 8 |
Improved conversion of adenosine to 3'-deoxyadenosine Chris Meier , Huynh-Dinh Tam Synlett 227-228 (1991) |
1990 | |
| 7 |
N-Aryl-O-(α-aminoacyl)hydroxylamine: Modellreaktionen zur Aktivierung von monocyclischen aromatischen Aminen zu ultimaten Carcinogenen durch α-Aminosäuren (N-aryl-O-(α-aminoacyl)hydroxylamines: model reactions for the activation of monocyclic aromatic amines into ultimate carcinogens with α-amino acids) Chris Meier , Gernot Boche Chemische Berichte 123, 1691-1698 (1990) |
| 6 |
N-Aryl-O-(α-aminoacyl)hydroxylamine: Modellreaktionen mit Desoxyguanosin, Guanosin und 5'-Guanosinmonophosphat zur Aktivierung monocyclischer aromatischer Amine (z. B. Phenacetin) zu ultimaten Carcinogenen (N-aryl-O-(α-aminoacyl)hydroxylamines: model reactions with deoxyguanosine, guanosine and 5'-guanosine monophosphate for the activation of monocyclic aromatic amines (e.g. phenacetin) into ultimate carcinogens) Chris Meier , Gernot Boche Chemische Berichte 123, 1699-1705 (1990) |
| 5 |
1H- und 13C-NMR-Konformationsanalysen und Minimal-Potential-Energie-Rechnungen an Desoxyguanosin-, Guanosin- und 5'-Guanosinmonophosphat-Addukten des Grenzcarcinogens 4-Methylanilin (Proton and carbon-13 NMR-conformational analysis and minimal-potential-energy calculations with deoxyguanosine, guanosine and 5'-guanosine monophosphate adducts of the borderline carcinogen 4-methylaniline) Chris Meier , Gernot Boche Chemische Berichte 123, 1707-1713 (1990) |
| 4 |
N-(α-Aminoacyloxy)-N-arylamines: activation of aromatic amines to ultimate carcinogens by amino acids Chris Meier , Gernot Boche Tetrahedron Letters 31, 1685-1688 (1990) |
| 3 |
N-Acetoxy-4-methoxyaniline, a model compound for the ultimate carcinogen of the phenacetin-related 4-ethoxyaniline Chris Meier , Gernot Boche Tetrahedron Letters 31, 1693-1696 (1990) |
1989 | |
| 2 |
α63-Aminosäuren als aktivierende Reagentien bei der Carcinogenese durch aromatische Amine: Modellreaktionen von monocyclischen N-(α63-Aminoacyloxy)arylaminen mit (Bio)Nukleophilen und Konformationsanalyse von arylaminmodifizierten Nukleosiden und Nukleotiden Chris Meier -/- Betreuer: Gernot Boche Dissertation, Marburg (1989), ISBN 978-3-926323-47-7; 3-926323-47-7 , Verlag: Intemann, Prien am Chiemsee |
1988 | |
| 1 |
Hydrazines and azo compounds from o-diphenylphosphinoyl arylhydroxylamines Gernot Boche, Chris Meier , Wolfgang Kleemiß Tetrahedron Letters 29, 1777-1780 (1988) |