Fachbereich Chemie
.
| Suche: FB Chemie / Hamburg | |
| 2025 | |
| 202 |
Chemosensory signalling in human sperm is controlled by Ca2+ influx via CatSper and Ca2+ clearance via plasma membrane Ca2+ ATPases Leonie Herrmann, Christoph Brenker, Teresa Mittermair, Vesna Bojovic, Jens Münchow, W. Felix Zhu, Carla Trugge, David Fußhöller, Jan Jikeli, Louisa Temme , U. Benjamin Kaupp, Timo Strünker British Journal of Pharmacology online: 27 February 2025 (2025) |
| 201 |
Isopeptidic Desferrioxamine Analogues: The Role of Hydroxamate Spacing for Chelation of Zr4+ Lasse Outzen, Darius Ludolfs, Maximilian Irl, Susanne Kossatz, Wolfgang Maison ChemMedChem 20, e202400890 (8 pp) (2025) |
| 200 |
Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy Joseph A. Newman, Angeline E. Gavard, Nergis Imprachim, Hazel Aitkenhead, Hadley E. Sheppard, Robert te Poele, Paul A. Clarke, Mohammad Anwar Hossain, Louisa Temme , Hans J. Oh, Carrow I. Wells, Zachary W. Davis-Gilbert, Paul Workman, Opher Gileadi, David H. Drewry Nature Communications 16, 1596 (2025) |
| 199 |
Byproducts in the synthesis of [68Ga]Ga-PSMA-11 Ata Makarem , Jianlin Han, Karel D. Klika Nature Protocols online: 18 April 2025 (2025) |
2024 | |
| 198 |
Model-informed precision dosing: State of the art and future perspectives Iris K. Minichmayr, Erwin Dreesen, Maddalena Centanni, Zhigang Wang, Yannick Hoffert, Lena E. Friberg, Sebastian G. Wicha Advanced Drug Delivery Reviews 215, 115421 (36 pp) (2024) |
| 197 |
Meropenem pharmacokinetics in cerebrospinal fluid: comparing intermittent and continuous infusion strategies in critically ill patients - a prospective cohort study Sebastian G. Wicha , Christina Kinast, Max Münchow, Sandra Wittova, Sebastian Greppmair, Alexandra K. Kunzelmann, Michael Zoller, Michael Paal, Michael Vogeser, Katharina Habler, Thomas Weig, Nicole Terpolilli, Suzette Heck, Konstantinos Dimitriadis, Christina Scharf, Uwe Liebchen Antimicrobial Agents and Chemotherapy 68, e00451-24 (13 pp) (2024) |
| 196 |
Reply to Gatti and Pea, "Are the pharmacokinetic data of meropenem studied in CSF of a mixed population composed of patients with cerebral infections and patients with extracerebral infections really helpful for clinicians treating CNS infections?" Sebastian G. Wicha , Christina Kinast, Max Münchow, Sandra Wittova, Sebastian Greppmair, Alexandra K. Kunzelmann, Michael Zoller, Michael Paal, Michael Vogeser, Katharina Habler, Thomas Weig, Nicole Terpolilli, Suzette Heck, Konstantinos Dimitriadis, Christina Scharf, Uwe Liebchen Antimicrobial Agents and Chemotherapy 68, e01468-24 (1 pp) (2024) |
| 195 |
Copper-catalyzed multicomponent reaction of β-trifluoromethyl β-diazo esters enabling the synthesis of β-trifluoromethyl N,N-diacyl-β-amino esters Youlong Du, Haibo Mei, Ata Makarem , Ramin Javahershenas, Vadim A. Soloshonok, Jianlin Han Beilstein Journal of Organic Chemistry 20, 212-219 (2024) |
| 194 |
Chimeric
antigen receptor T-cell therapy and fludarabine: precision dosing imperatives Sebastian G. Wicha , Eva M. A. Wansing, Adrin Dadkhah, Francis A. Ayuk, Nicolaus M. Kröger, Claudia Langebrake Blood Advances 8, 797-798 (2024) |
| 193 |
One-step hydrothermal synthesis of a green NiCo-LDHs-rGO composite for the treatment of lead ion in aqueous solutions Ata Makarem , Alireza Aldaghi, Mohammad Gheibi, Mohammad Eftekhari, Kourosh Behzadian Canadian Journal of Chemical Engineering 102, 1248-1261 (2024) Reprint: Trending Topics in Chemical Engineering (2022-2024) (2024) |
| 192 |
Regulation of the Activity of the Dual Leucine Zipper Kinase by Distinct Mechanisms Kyra-Alexandra Köster, Marten Dethlefs, Jorge Duque Escobar, Elke Oetjen Cells 13, 333 (2024) |
| 191 |
Decoration of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) with N-oxides increases the T1 relaxivity of Gd-complexes Svenja Kerpa, Verena R. Schulze, Malte Holzapfel, Lina Cvancar, Markus Fischer , Wolfgang Maison ChemistryOpen 13, e202300298 (8 pp) (2024) |
| 190 |
FDA approved fluorine-containing drugs in 2023 Qian Wang, Yeping Bian, Gagan Dhawan, Wei Zhang, Alexander E. Sorochinsky, Ata Makarem , Vadim A. Soloshonok, Jianlin Han Chinese Chemical Letters 35, 109780 (2024) |
| 189 |
Impact of Key Components of Intensified Ceftaroline Dosing on Pharmacokinetic/Pharmacodynamic Target Attainment Iris K. Minichmayr, Sebastian G. Wicha , Peter Matzneller, Charlotte Kloft, Markus Zeitlinger Clinical Pharmacokinetics 63, 121-131 (2024) |
| 188 |
Pharmacokinetic/pharmacodynamic evaluation of tigecycline dosing in a hollow fiber infection model against clinical bla-KPC producing Klebsiella Pneumoniae isolates Lisa F. Amann, Astrid Broeker, Maria Riedner , Holger Rohde , Jiabin Huang, Patrice Nordmann, Jean-Winoc Decousser, Sebastian G. Wicha Diagnostic Microbiology and Infectious Disease 108, 116153 (8 pp) (2024) |
| 187 |
Mixed Liquid and Solid Phase Synthesis of Isopeptidic Desferrioxamine Analogues for Complexation of Zirconium Lasse Outzen, Hoang Duc Nguyen, Darius Ludolfs, Wolfgang Maison European Journal of Organic Chemistry 27, e202400266 (5 pp) (2024) |
| 186 |
Towards a better detection of patients at-risk of linezolid toxicity in clinical practice: a prospective study in three Belgian hospital centers Hélène Thirot, David Fage, Antonia Leonhardt, Philippe Clevenbergh, Tatiana Besse-Hammer, Jean Cyr Yombi, Olivier Cornu, Caroline Briquet, Maya Hites, Frédérique Jacobs, Gert-Jan Wijnant, Sebastian G. Wicha , Frédéric Cotton, Paul M. Tulkens, Anne Spinewine, Françoise van Bambeke1 Frontiers in Pharmacology 15, 1310309 (11 pp) (2024) |
| 185 |
Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients Lea Marie Schatz, Sebastian Greppmair, Alexandra K. Kunzelmann, Johannes Starp, Alexander Brinkmann, Anka Roehr, Otto Frey, Stefan Hagel, Christoph Dorn, Michael Zoller, Christina Scharf, Sebastian G. Wicha , Uwe Liebchen International Journal of Antimicrobial Agents 64, 107305 (2024) |
| 184 |
Iodinated PSMA Ligands as XFI Tracers for Targeted Cell Imaging and Characterization of Nanoparticles Svenja Kerpa, Malte Holzapfel, Theresa Staufer, Robert Kuhrwahl, Marina Mutas, Stefan Werner, Verena R. Schulze, Pascal Nakielski, Neus Feliu , Elke Oetjen , Jannis Haak, Florian Ziegler, Rasmus Buchin, Jili Han, Wolfgang J. Parak , Florian Grüner , Wolfgang Maison International Journal of Molecular Sciences 25, 11880 (13 pp) (2024) |
| 183 |
Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU Beatrix Wulkersdorfer, Felix Bergmann, Lisa Amann, Alexandra Fochtmann-Frana, Valentin Al Jalali, Elizaveta Kurdina, Edith Lackner, Sebastian G. Wicha , Christoph Dorn, Bruno Schäfer, Gerald Ihra, Thomas Rath, Christine Radtke, Markus Zeitlinger Journal of Antimicrobial Chemotherapy 79, 262-270 (2024) |
| 182 |
Pharmacokinetics and pharmacological target attainment of standard temocillin dosing in non-critically ill patients with complicated urinary tract infections Gert-Jan Wijnant, Perrin Ngougni Pokem, Marie Coessens, Eleonora Cottone, Julian Ermtraud, Lieven Goeman, Steven Vervaeke, Sebastian G. Wicha , Françoise van Bambeke Journal of Antimicrobial Chemotherapy 79, 2204-2212 (2024) |
| 181 |
External oxidants in gold-catalyzed cross-coupling reactions Manankar Koley, Jianlin Han, Vadim A. Soloshonok, Subhajit Mojumder, Ramin Javahershenas, Ata Makarem Journal of Coordination Chemistry 77, 1-48 (2024) |
| 180 |
Medicinal Chemistry of Drugs with N-Oxide Functionalities Michelle Kobus, Timo Friedrich, Eilika Zorn, Nils Burmeister, Wolfgang Maison Journal of Medicinal Chemistry 67, 5168-5184 (2024) |
| 179 |
Visible-Light-Triggered Difluoroacetylation/Cyclization of Chromone-Tethered Alkenes Enabling Synthesis of Tetrahydroxanthones Chengting Wang, Jingrui He, Haibo Mei, Ata Makarem , Jianlin Han Journal of Organic Chemistry 89, 5619-5633 (2024) |
| 178 |
An improved immobilized molybdenum oxidative catalyst bearing an amino acid-derived bifunctional chelator Elham Safaei, Vahideh Dolatyari, Iraj Saberikia, Babak Karimi, Karel D. Klika, Ata Makarem Journal of Organometallic Chemistry 1010, 123099 (9 pp) (2024) |
| 177 |
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): An Emerging Tool in Radiopharmaceutical Science Karel D. Klika, Jianlin Han, Marvin S. Busse, Vadim A. Soloshonok, Ramin Javahershenas, Frank Vanhaecke, Ata Makarem Journal of the American Chemical Society 146, 30717-30727 (2024) |
| 176 |
Warum anlassloses Testen (fast immer) zufriedenstellt - auch wenn es (fast immer) schadet Ingrid Mühlhauser KVH-Journal (2) 20-23 (2024) Reprint: EbM-Kolumne 25.01.2024 (2024) |
| 175 |
Investorgetragene renditeorientierte Patientenversorgung. Sind die Studienergebnisse auf das deutsche Gesundheitssystem übertragbar? Ingrid Mühlhauser, Gabriele Meyer KVH-Journal (5) 24-29 (2024) |
| 174 |
Wann ist es Screening - wann medizinisch indizierte Diagnostik? Testen auf Trisomie und die jährliche Inspektion beim Frauenarzt Ingrid Mühlhauser KVH-Journal (9) 20-23 (2024) |
| 173 |
Pharmacokinetic/pharmacodynamic analysis of ceftazidime/avibactam and fosfomycin combinations in an in vitro hollow fiber infection model against multidrug-resistant Escherichia coli Niklas Krömer, Lisa F. Amann, Aneeq Farooq, Christoph Pfaffendorf, Miklas Martens, Jean-Winoc Decousser, Nicolas Grégoire, Patrice Nordmann, Sebastian G. Wicha Microbiology Spectrum 12, e03318-23 (12 pp) (2024) |
| 172 |
Revised taxon definition in European Cortinarius subgenus Dermocybe based on phylogeny, chemotaxonomy, and morphology Lesley Rosina Huymann, Anna Hannecker, Turrini Giovanni, Kare Liimatainen, Tuula Niskanen, Maraike Probst, Ursula Peintner, Bianka Siewert Mycological Progress 23, 26 (30 pp) (2024) |
| 171 |
Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data Mohamed Maiga, Laurent Dembele, Perrine Courlet, Akash Khandelwal, Antoine Dara, Fanta Sogore, Ousmaila Diakité, Fatoumata O. Maiga, François Dao, Sekou Sissoko, Yacouba Barre, Siaka Goita, Mahamadou Diakite, Seidina A. S. Diakite, Abdoulaye A. Djimde, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha , Claudia Demarta-Gatsi Nature Communications 15, 7659 (11 pp) (2024) |
| 170 |
How Iranian students can master integration into German academia Ata Makarem , Karel Douglas Klika Nature Physics 20, 678-679 (2024) |
| 169 |
Synthesis of a model phyllobilin bearing an optical marker Anh Thu Nguyen Tran, Pengzhi Wang, Shaofei Zhang, Milena Jovanovic, Bianka Siewert , Simone Moser, Jonathan S. Lindsey New Journal of Chemistry 48, 12091-12101 (2024) |
| 168 |
Synthesis of dithioacetals via nucleophilic substitution and their antifungal activity evaluation Jiaqing Shao, Yeping Bian, Qian Wang, Haibo Mei, Ata Makarem , Vadim A. Soloshonok, Jianlin Han Organic & Biomolecular Chemistry 22, 8418-8422 (2024) |
| 167 |
An Investigation on the Relationship between Dust Emission and Air Flow as Well as Particle Size with a Novel Containment Two-Chamber Setup Steffen Wirth, Martin Schöler, Jonas Brügmann, Claudia S. Leopold Pharmaceutics 16, 1088 (17 pp) (2024) |
| 166 |
Ätherische Öle - botanische und chemische Grundlagen Elisabeth Stahl-Biskup Pharmakon 12, 423-429 (2024) |
| 165 |
Investigations on the dustiness of binary acetaminophen - lactose monohydrate powder blends Steffen Wirth, Martin Schöler, Claudia S. Leopold Powder Technology 448, 120317 (10 pp) (2024) |
| 164 |
Recent advances in microwave-assisted multicomponent synthesis of spiro heterocycles Ramin Javahershenas, Ata Makarem , Karel D. Klika RSC Advances 14, 5547-5565 (2024) |
| 163 |
Latest developments in coumarin-based anticancer agents: mechanism of action and structure-activity relationship studies Manankar Koley, Jianlin Han, Vadim A. Soloshonok, Subhajit Mojumder, Ramin Javahershenas, Ata Makarem RSC Medicinal Chemistry 15, 10-54 (2024) |
| 162 |
Histone variant H3.5 in testicular cell differentiation and its interactions with histone chaperones Patrick Philipp Weil, Anton Pembaur, Beatrice Wirth, Eda Oetjen, Hannes Büsscher, Klemens Zirngibl, Malte Czarnetzki, Stella Braun, Jann-Frederik Cremers, Daniel Gödde, Stephan Degener, Jan Postberg Scientific Reports 14, 30564 (2024) |
| 161 |
Recent Advances in the Multicomponent Synthesis of Heterocycles Using 5-Aminotetrazole Ramin Javahershenas, Haibo Mei, Manankar Koley, Vadim A. Soloshonok, Ata Makarem Synthesis 56, 2445-2461 (2024) |
| 160 |
Visible-light-promoted cyclization of 3-indolylallylamides enabling synthesis of tetrahydrocarbolinones Jingrui He, Chengting Wang, Haibo Mei, Ata Makarem , Vadim A. Soloshonok, Jianlin Han Tetrahedron 150, 133776 (11 pp) (2024) |
| 159 |
Best Practice for Therapeutic Drug Monitoring of Infliximab: Position Statement from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Dahham Alsoud, Dirk Jan A. R. Moes, Zhigang Wang, Rani Soenen, Zohra Layegh, Murray Barclay, Tomoyuki Mizuno, Iris K. Minichmayr, Ron J. Keizer, Sebastian G. Wicha , Gertjan Wolbink, Jo Lambert, Séverine Vermeire, Annick de Vries, Konstantinos Papamichael, Núria Padullés-Zamora, Erwin Dreesen Therapeutic Drug Monitoring 46, 291-308 (2024) |
| 158 |
Aufarbeitung der Corona-Pandemiemaßnahmen - Evidenzbasierte Risikokommunikation muss ein zentrales Thema sein (Evaluation of the public health measures introduced during the coronavirus pandemic: Evidence-based risk communication must be a central topic) Ingrid Mühlhauser, Johannes Pantel, Gabriele Meyer Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen 186, 35-42 (2024) |
| 157 |
Mündige Patient:innen: Empowerment oder Überforderung? Ingrid Mühlhauser -/- Herausgeber: Christoph Straub Transparenz im Gesundheitswesen. Vertrauen. Wissen. Partizipation 61-67 (2024), ISBN 978-3-95466-803-8 , Verlag: MWV Medizinisch Wissenschaftliche Verlagsgesellschaft, Berlin |
| 156 |
Material
mit langfristigen Antifouling-Eigenschaften (Method for polymer grafting on elastomer or polyamide surfaces) Fabrizio Pagnanelli, Wolfgang Maison , Nils Burmeister -/- Anmelder: Dunlop Oil & Marine LTD, Universität Hamburg Patent: DE 102022210770 (A1) 2024-04-18 |
2023 | |
| 155 |
Surface Grafted N-Oxides have Low-Fouling and Antibacterial Properties Nils Burmeister, Eilika Zorn, Aneeq Farooq, Lena Preuss, Christel Vollstedt, Timo Friedrich, Tomi Mantel, Nico Scharnagl, Marcus Rohnke, Mathias Ernst , Sebastian G. Wicha , Wolfgang R. Streit, Wolfgang Maison Advanced Materials Interfaces 10, 2300505 (13 pp) (2023) |
| 154 |
Alkali salts of amino acids as alkaline additives for neutralization of acidic corrosion inhibitors Tim Naundorf, Tom Seddig, Erik Ruf, Laurens Ballentin, Helmut Kipphardt, Wolfgang Maison Amino Acids 55, 665-678 (2023) |
| 153 |
Acute-on-chronic liver failure alters linezolid pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study Tjokosela Tikiso, Valentin Fuhrmann, Christina König, Dominik Jarczak, Stefanie Iwersen-Bergmann, Stefan Kluge, Sebastian G. Wicha , Jörn Grensemann Annals of Intensive Care 13, 83 (10 pp) (2023) |
| 152 |
An improved PKPD modeling approach to characterize the pharmacodynamic interaction over time between ceftazidime/avibactam and colistin from in vitro time-kill experiments against multidrug-resistant Klebsiella pneumoniae isolates Romain Aubry, Julien Buyck, Laure Prouvensier, Jean-Winoc Decousser, Patrice Nordmann, Sebastian G. Wicha , Sandrine Marchand, Nicolas Grégoire Antimicrobial Agents and Chemotherapy 67, e00301-23 (16 pp) (2023) |
| 151 |
Recent Advances in the Multicomponent Electro-Organic (Electrochemical) Synthesis of Heterocycles Sahar Imeni, Ata Makarem , Ramin Javahershenas Asian Journal of Organic Chemistry 12, e202300303 (21 pp) (2023) |
| 150 |
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition Maurice Dellin, Ina Rohrbeck, Purva Asrani, Julian A. Schreiber, Nadine Ritter, Frank Glorius, Bernhard Wünsch , Thomas Budde, Louisa Temme , Timo Strünker, Birgit Stallmeyer, Frank Tüttelmann, Sven G. Meuth, Marc Spehr, Johann Matschke, Andrea Steinbicker, Christos Gatsogiannis, Raphael Stoll, Nathalie Strutz-Seebohm, Guiscard Seebohm Biological Chemistry 404, 241-254 (2023) |
| 149 |
Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors Stefan Wimmer, Katharina Hoff, Benedikt Martin, Martin Grewer, Laura Denni, Raquel Lascorz Massanet, Maria Valeria Raimondi, Emre F. Bülbül, Jelena Melesina, Sven-Kevin Hotop, Jörg Haupenthal, Holger Rohde , Peter Heisig, Anna K. H. Hirsch, Mark Brönstrup, Wolfgang Sippl, Ralph Holl Bioorganic Chemistry 131, 106331 (2023) |
| 148 |
Adaptation of a population pharmacokinetic model to inform tacrolimus therapy in heart transplant recipients Ranita Kirubakaran, David W. Uster, Stefanie Hennig, Jane E. Carland, Richard O. Day, Sebastian G. Wicha , Sophie L. Stocker British Journal of Clinical Pharmacology 89, 1162-1175 (2023) |
| 147 |
CYP19A1 mediates severe SARS-CoV-2 disease outcome in males Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Kouassi Mounogou, Berfin Schaumburg, Fabian Stoll, Amirah Al Jawazneh, Zoé Schmal, Tian Bai, Martin Zickler, Georg Beythien, Kathrin Becker, Madeleine de la Roi, Fabian Heinrich, Claudia Schulz, Martina Sauter, Susanne Krasemann, Philine Lange, Axel Heinemann, Debby van Riel, Lonneke Leijten, Lisa Bauer, Thierry P. P. van den Bosch, Boaz Lopuhaä, Tobias Busche, Daniel Wibberg, Dirk Schaudien, Torsten Goldmann, Anna Lüttjohann, Jenny Ruschinski, Hanna Jania, Zacharias Müller, Vinicius Pinho dos Reis, Vanessa Krupp-Buzimkic, Martin Wolff, Chiara Fallerini, Margherita Baldassarri, Simone Furini, Katrina Norwood, Christopher Käufer, Nina Schützenmeister Cell Reports Medicine 4, 101152 (27 pp) (2023) |
| 146 |
Synthesis of Modular Desferrioxamine Analogues and Evaluation of Zwitterionic Derivatives for Zirconium Complexation Lasse Outzen, Moritz Münzmay, John V. Frangioni, Wolfgang Maison ChemMedChem 18, e202300112 (15 pp) (2023) |
| 145 |
Pharmacokinetics of Ribavirin in the Treatment of Lassa Fever: An Observational Clinical Study at the Irrua Specialist Teaching Hospital, Edo State, Nigeria Mirjam Groger, Peter Akhideno, Christine J. Kleist, Femi O. Babatunde, Osahogie Edeawe, Julia Hinzmann, ThankGod Akhigbe, Joy Nwatuzor, Gloria Eifediyi, Jonas Müller, Mette Hinrichs, Meike Pahlmann, Francisca Naana Sarpong, Christine Wagner, Anke Thielebein, Louis Aihonwalan, Till Koch, Maria Riedner , Ephraim Ogbaini-Emovon, Sylvanus Okogbenin, Stephan Günther , Sebastian G. Wicha , Michael Ramharter, Lisa Oestereich, Sophie Duraffour, Cyril Erameh Clinical Infectious Diseases 76, e841-e848 (2023) |
| 144 |
Pilot Pharmacokinetic Study in Healthy Adults Using Intravascular Microdialysis Catheters Modified for Use in Paediatric Patients to Assess Vancomycin Blood Levels Valentin Al Jalali, Martin Bauer, Michael Wölfl-Duchek, Maysa Sarhan, Sebastian G. Wicha , Stefan Poschner, Walter Jäger, Franz König, Christoph Male, Markus Zeitlinger Clinical Pharmacokinetics 62, 77-87 (2023) |
| 143 |
Zwitterionic
surface modification of polyethylene via atmospheric plasma-induced polymerization of (vinylbenzyl-)sulfobetaine and evaluation of antifouling properties Nils Burmeister, Christel Vollstedt, Cathrin Kröger, Timo Friedrich, Nico Scharnagl, Marcus Rohnke, Eilika Zorn, Sebastian G. Wicha , Wolfgang R. Streit, Wolfgang Maison Colloids and Surfaces B: Biointerfaces 224, 113195 (2023) |
| 142 |
Unsupervised meta-clustering identifies risk clusters in acute myeloid leukemia based on clinical and genetic profiles Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Peter Heisig, Sebastian Stasik, Julia-Annabell Georgi, Frank Kroschinsky, Friedrich Stölzel, Uwe Platzbecker, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang Hiddemann, Carsten Müller-Tidow, Hubert Serve, Claudia D. Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan W. Krause, Mathias Hänel, Wolfgang E. Berdel, Christoph Schliemann, Jiri Mayer, Maher Hanoun, Johannes Schetelig, Karsten Wendt, Martin Bornhäuser, Christian Thiede, Jan Moritz Middeke Communications Medicine 3, 68 (2023) |
| 141 |
Editorial: Pharmacology of infectious diseases: world tuberculosis day 2022 Shashikant Srivastava, Johannes W. Alffenaar, Sebastian G. Wicha Frontiers in Pharmacology 14, 1233347 (3 pp) (2023) |
| 140 |
Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning. Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke Haematologica 108, 690-704 (2023) |
| 139 |
Individualised dosing of antibiotics in ICU patients: timing, target and model selection matter Uwe Liebchen, Josef Briegel, Alexander Brinkmann, Otto Frey, Sebastian G. Wicha Intensive Care Medicine 49, 475-476 (2023) |
| 138 |
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting Sebastian Greppmair, Alexander Brinkmann, Anka Roehr, Otto Frey, Stefan Hagel, Christoph Dorn, Amélie Marsot, Ibrahim El-Haffaf, Michael Zoller, Thomas Saller, Johannes Zander, Lea Marie Schatz, Christina Scharf, Josef Briegel, Iris K. Minichmayr, Sebastian G. Wicha , Uwe Liebchen Intensive Care Medicine 49, 966-976 (2023) |
| 137 |
Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities Katharina Holzapfel, Thomas Rades, Claudia S. Leopold International Journal of Pharmaceutics 636, 122840 (2023) |
| 136 |
Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination Maria Sanz-Codina, Sebastian G. Wicha , Beatrix Wulkersdorfer, Valentin Al Jalali, Wisse van Os, Matthias G. Vossen, Martin Bauer, Edith Lackner, Christoph Dorn, Markus Zeitlinger Journal of Antimicrobial Chemotherapy 78, 380-388 (2023) |
| 135 |
Evaluation of in vitro pharmacodynamic drug interactions of ceftazidime/avibactam and fosfomycin in Escherichia coli Niklas Krömer, Miklas Martens, Jean-Winoc Decousser, Nicolas Grégoire, Patrice Nordmann, Sebastian G. Wicha Journal of Antimicrobial Chemotherapy 78, 2524-2534 (2023) |
| 134 |
Application of feature-based molecular networking in the field of algal research with special focus on mycosporine-like amino acids Michael J. Zwerger, Fabian Hammerle, Bianka Siewert , Markus Ganzera Journal of Applied Phycology 35, 1377-1392 (2023) |
| 133 |
Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach Mark James Horgan, Lukas Zell, Bianka Siewert , Hermann Stuppner, Daniela Schuster, Veronika Temml Journal of Chemical Information and Modeling 63, 6396-6411 (2023) |
| 132 |
Drug Combination Modeling: Methods and Applications in Drug Development Rachael A. Pearson, Sebastian G. Wicha , Malek Okour Journal of Clinical Pharmacology 63, 151-165 (2023) |
| 131 |
A Model-Based Tool for Guiding Infliximab Induction Dosing to Maximize Long-term Deep Remission in Children with Inflammatory Bowel Diseases Wannee Kantasiripitak, Sebastian G. Wicha , Debby Thomas, Ilse Hoffman, Marc Ferrante, Séverine Vermeire, Karen van Hoeve, Erwin Dreesen Journal of Crohn's & Colitis 17, 896-908 (2023) |
| 130 |
Pretomanid-resistant tuberculosis Niklas Köhler, Sönke Andres, Matthias Merker, Viola Dreyer, Agnieszka John, Martin Kuhns, David Krieger, Eva Choong, Nick Verougstraete, Pia Abel zur Wiesch, Sebastian G. Wicha , Christina König, Barbara Kalsdorf, Patricia M. Sanchez Carballo, Dagmar Schaub, Jim Werngren, Thomas Schön, Charles A. Peloquin, Nicolas Schönfeld, Alain G. Verstraete, Laurent A. Decosterd, Rob E. Aarnoutse, Stefan Niemann, Florian P. Maurer, Christoph Lange Journal of Infection 86, 520-524 (2023) |
| 129 |
Hydrothermally synthesized tannic acid-copper(I) complex-based nanoparticles for efficient decontamination of lead ions from aqueous solutions Ata Makarem , Mohammad Gheibi, Razieh Mirsafaei, Mohammad Eftekhari Journal of Molecular Liquids 388, 122743 (12 pp) (2023) |
| 128 |
Fungal Anthraquinone Photoantimicrobials Challenge the Dogma of Cationic Photosensitizers Fabian Hammerle, Johannes Fiala, Anja Höck, Lesley Huymann, Pamela Vrabl, Yurii Husiev, Sylvestre Bonnet, Ursula Peintner, Bianka Siewert Journal of Natural Products 86, 2247-2257 (2023) |
| 127 |
Operational characteristics of full random effects modelling ('frem') compared to stepwise covariate modelling ('scm') Lisa F. Amann, Sebastian G. Wicha Journal of Pharmacokinetics and Pharmacodynamics 50, 315-326 (2023) |
| 126 |
Und nochmals Vitamin D - Welche Erkenntnis bringt eine Mendel-randomisierte Kohortenstudie? Ingrid Mühlhauser KVH-Journal (2) 30-33 (2023) |
| 125 |
Dramatische Effekte: Wann braucht es kein RCT und wann doch - am Beispiel Jodmangel Ingrid Mühlhauser KVH-Journal (7-8) 24-27 (2023) |
| 124 |
Wirksame Kontrollmaßnahmen in der SARS-CoV-2-Pandemie? Aus dem Netzwerk evidenzbasierte Medizin. Eine kritische Reflexion der RKI-"StopptCOVID"-Studie aus Sicht der evidenzbasierten Medizin Gabriele Meyer, Ingrid Mühlhauser, Ralph Brinks, Bernhard Mülle KVH-Journal (10) 20-23 (2023) |
| 123 |
Contact-Biocide TiO2 Surfaces by Surface-Initiated Atom Transfer Radical Polymerization with Chemically Stable Phosphonate Initiators Eilika Zorn, J. Iven H. Knaack, Nils Burmeister, Nico Scharnagl, Marcus Rohnke, Sebastian G. Wicha , Wolfgang Maison Langmuir 39, 11063-11072 (2023) |
| 122 |
Low-Fouling and Antibacterial Polymer Brushes via Surface-Initiated Polymerization of a Mixed Zwitterionic and Cationic Monomer Nils Burmeister, Eilika Zorn, Lena Preuss, Donovan Timm, Nico Scharnagl, Marcus Rohnke, Sebastian G. Wicha , Wolfgang R. Streit, Wolfgang Maison Langmuir 39, 17959-17971 (2023) |
| 121 |
Glucamines as green alternatives to conventional amino alcohols in metalworking fluids Tom Seddig, Tim Naundorf, Helmut Kipphardt, Wolfgang Maison Materials and Corrosion 74, 394-402 (2023) |
| 120 |
Increase of c-FOS promoter transcriptional activity by the dual leucine zipper kinase Kyra-Alexandra Köster, Jorge Duque Escobar, Anja Fietkau, Regina Toledo, Elke Oetjen Naunyn-Schmiedeberg's Archives of Pharmacology 396, 1223-1233 (2023) |
| 119 |
A Single-Run HPLC-MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis Niklas Köhler, Hande Karakoese, Hans-Peter Grobbel, Doris Hillemann, Sönke Andres, Christina König, Barbara Kalsdorf, Thomas Theo Brehm, Laura Böttcher, Inna Friesen, Harald Hoffmann, Drazen Strelec, Dagmar Schaub, Charles A. Peloquin, Stefan Schmiedel, Laurent A. Decosterd, Eva Choong, Sebastian G. Wicha , Rob E. Aarnoutse, Christoph Lange, Patricia M. Sanchez Carballo Pharmaceutics 15, 2543 (23 pp) (2023) |
| 118 |
Growth, morphology, and formation of cinnabarin in Pycnoporus cinnabarinus in relation to different irradiation spectra Christoph W. Schinagl, Bianka Siewert , Fabian Hammerle, Gaja Spes, Ursula Peintner, Michael Schlierenzauer, Pamela Vrabl Photochemical & Photobiological Sciences 22, 2861-2875 (2023) |
| 117 |
Light in the box - photobiological examination chamber with light trap ventilation system for studying fungal surface cultures illustrated with Metarhizium brunneum and Beauveria brongniartii Pamela Vrabl, Maria Zottele, Lucia Colleselli, Christoph Walter Schinagl, Laura Mayerhofer, Bianka Siewert , Hermann Strasser Research Square Preprint 2572234 (2023) |
| 116 |
Co-cultivation of Mortierellaceae with Pseudomonas helmanticensis affects both their growth and volatilome Maraike Probst, Anusha Telagathoti, Bianka Siewert , Iuliia Khomenko, Emanuela Betta, Franco Biasioli, Ursula Peintner Scientific Reports 13, 2213 (15 pp) (2023) |
2022 | |
| 115 |
Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction Christine J. Kleist, Chi-Un Choe, Dorothee Atzler, Mirjam Schönhoff, Rainer Böger, Edzard Schwedhelm, Sebastian G. Wicha Amino Acids 54, 889-896 (2022) |
| 114 |
Tigecycline Dosing Strategies in Critically Ill Liver-Impaired Patients Lisa F. Amann, Rawan Alraish, Astrid Broeker, Magnus Kaffarnik, Sebastian G. Wicha Antibiotics 11, 479 (12 pp) (2022) |
| 113 |
New in vitro interaction-parasite reduction ratio assay for early derisk in clinical development of antimalarial combinations Sebastian G. Wicha , Annabelle Walz, Mohammed H. Cherkaoui-Rbati, Nils Bundgaard, Karsten Kuritz, Christin Gumpp, Nathalie Gobeau, Jörg Möhrle, Matthias Rottmann, Claudia Demarta-Gatsi Antimicrobial Agents and Chemotherapy 66, 00556-22 (2022) |
| 112 |
Population pharmacokinetics and target attainment analysis of linezolid in multidrug-resistant tuberculosis patients Anna K. Tietjen, Niklas Krömer, Dario Cattaneo, Sara Baldelli, Sebastian G. Wicha British Journal of Clinical Pharmacology 88, 1835-1844 (2022) |
| 111 |
Efficient
Copper-Catalyzed Highly Stereoselective Synthesis of Unprotected C-Acyl Manno-, Rhamno- and Lyxopyranosides Gordon Jacob Boehlich, Hannes Sterzel, Julia Rehbein , Nina Schützenmeister Chemistry - A European Journal 28, e202202619 (10 pp) (2022) |
| 110 |
Identification of 4-Anilinoquin(az)oline as a Cell-Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype Christopher R. M. Asquith , Louisa Temme , Michael P. East, Tuomo Laitinen, Julie Pickett, Frank E. Kwarcinski, Parvathi Sinha, Carrow I. Wells, Gary L. Johnson, Reena Zutshi, David H. Drewry ChemMedChem 17, e202200161 (10 pp) (2022) |
| 109 |
Fungal Anthraquinone Photoantimicrobials Challenge the Dogma of Cationic Photosensitizers Fabian Hammerle, Johannes Fiala, Anja Höck, Lesley Huymann, Pamela Vrabl, Yurii Husiev, Sylvestre Bonnet, Ursula Peintner, Bianka Siewert ChemRxiv 2022-7h8vn (2022) |
| 108 |
A dosing nomograph for cerebrospinal fluid penetration of meropenem applied by continuous infusion in patients with nosocomial ventriculitis Christina König, Jörn Grensemann, Patrick Czorlich, Eckhard Schlemm, Stefan Kluge, Sebastian G. Wicha Clinical Microbiology and Infection 28, 1022.e9-1022.e16 (2022) |
| 107 |
Pharmacokinetics and Pharmacodynamics of Tedizolid Khalid Iqbal, Aliki Milioudi, Sebastian G. Wicha Clinical Pharmacokinetics 61, 489-503 (2022) |
| 106 |
Optimized sampling to estimate vancomycin drug exposure: Comparison of pharmacometric and equation-based approaches in a simulation-estimation study David W. Uster, Sebastian G. Wicha CPT: Pharmacometrics & Systems Pharmacology 11, 711-720 (2022) |
| 105 |
Multi-model averaging improves the performance of model-guided infliximab dosing in patients with inflammatory bowel diseases Wannee Kantasiripitak, An Outtier, Sebastian G. Wicha , Alexander Kensert, Zhigang Wang, João Sabino, Séverine Vermeire, Debby Thomas, Marc Ferrante, Erwin Dreesen CPT: Pharmacometrics & Systems Pharmacology 11, 1045-1059 (2022) |
| 104 |
Synthesis of a polyaminocarboxylate-based aluminum complex and its structural studies using 1H{13C}-HMBC NMR and a Karplus-type function Karel D. Klika, Rana Alsalim, Mohammad Eftekhari, Ata Makarem Dalton Transactions 51, 12436-12441 (2022) |
| 103 |
Solution Structure and Relaxivity of Ln-DOTXAZA Derivatives Malte Holzapfel, Torben Baldau, Svenja Kerpa, Gianmarco Guadalupi, Bing Qi, Yang Liu, Wolfgang J. Parak , Wolfgang Maison European Journal of Inorganic Chemistry e202200432 (9 pp) (2022) |
| 102 |
N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase Niels Heise, Sander Friedrich, Veronika Temml, Daniela Schuster, Bianka Siewert , René Csuk European Journal of Medicinal Chemistry 227, 113947 (11 pp) (2022) |
| 101 |
Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: an evaluation of in vitro, in vivo methodologies and human studies Jan-Willem C. Alffenaar, Jurriaan E. M. de Steenwinkel, Andreas H. Diacon, Ulrika S. H. Simonsson, Shashikant Srivastava, Sebastian G. Wicha Frontiers in Pharmacology 13, 1063453 (13 pp) (2022) |
| 100 |
Population pharmacokinetics and toxicodynamics of continuously infused linezolid in critically ill patients Sebastian G. Wicha , Andrea Mair, Ute Chiriac, Otto R. Frey, Thomas Fuchs, Max Gaasch, Stefan Hagel. Daniel C. Richter, Jason A. Roberts, Anka C. Röhr, Markus A. Weigand, Alexander Brinkmann International Journal of Antimicrobial Agents 59, 106572 (2022) |
| 99 |
Model-informed precision dosing of vancomycin via continuous infusion: a clinical fit-for-purpose evaluation of published PK models Astrid Heus, David W. Uster, Veerle Grootaert, Nele Vermeulen, Annemie Somers, Diana Huis in't Veld, Sebastian G. Wicha , Pieter A. de Cock International Journal of Antimicrobial Agents 59, 106579 (2022) |
| 98 |
Co-amorphization of enantiomers - Investigation of the amorphization process, the physical stability and the dissolution behavior Katharina Holzapfel, Jingwen Liu, Thomas Rades, Claudia S. Leopold International Journal of Pharmaceutics 616, 121552 (2022) |
| 97 |
A pharmacokinetic-pharmacodynamic (PKPD) model-based analysis of tedizolid against enterococci using the hollow-fibre infection model Khalid Iqbal, H. Rohde, J. Huang, T. Tikiso, Lisa F. Amann, Markus Zeitlinger, Sebastian G. Wicha Journal of Antimicrobial Chemotherapy 77, 2470-2478 (2022) |
| 96 |
Understanding the suitability of established antibiotics for oral inhalation from a pharmacokinetic perspective: an integrated model-based investigation based on rifampicin, ciprofloxacin and tigecycline in vivo data Anneke Himstedt, Clemens Braun, Sebastian G. Wicha , Jens Markus Borghardt Journal of Antimicrobial Chemotherapy 77, 2922-2932 (2022) |
| 95 |
Inferring pulmonary exposure based on clinical PK data: accuracy and precision of model-based deconvolution methods Anneke Himstedt, Jens Markus Borghardt, Sebastian G. Wicha Journal of Pharmacokinetics and Pharmacodynamics 49, 135-149 (2022) |
| 94 |
Defined Coadsorption of Prostate Cancer Targeting Ligands and PEG on Gold Nanoparticles for Significantly Reduced Protein Adsorption in Cell Media Finn Höeg, Jennifer Schulz, Sebastian Graf, Dina Salah, Sharah Chandralingam, Wolfgang Maison , Wolfgang J. Parak , Florian Schulz Journal of Physical Chemistry C 126, 20594-20604 (2022) Reprint: Horst Weller Festschrift |
| 93 |
A convenient separation strategy for fungal anthraquinones by centrifugal partition chromatography Fabian Hammerle, Michael Zwerger, Anja Höck, Markus Ganzera, Ursula Peintner, Bianka Siewert Journal of Separation Science 45, 1031-1041 (2022) |
| 92 |
Übersterblichkeit in der Pandemie. Wie valide sind die Vergleiche Deutschland versus Schweden? Ingrid Mühlhauser KVH-Journal (9) 30-33 (2022) |
| 91 |
Bewegungsprogramme für gebrechliche ältere Menschen. Wenn ein Interpretationsbias den Blick auf unerwünschte Nebeneffekte verstellt Gabriele Meyer, Ingrid Mühlhauser KVH-Journal (10) 20-22 (2022) |
| 90 |
Research priorities towards precision antibiotic therapy to improve patient care Zackery P. Bulman, Sebastian G. Wicha , Elisabet I. Nielsen, Justin R. Lenhard, Roger L. Nation, Ursula Theuretzbacher, Hartmut Derendorf, Thomas Tängdén, Markus Zeitlinger, Cornelia B. Landersdorfer, Jürgen B. Bulitta, Lena E. Friberg, Jian Li, Brian T. Tsuji Lancet. Microbe 3, e795-e802 (2022) |
| 89 |
Molecular Insight into Gene Response of Diorcinol- and Rubrolide-Treated Biofilms of the Emerging Pathogen Stenotrophomonas maltophilia Mirja Gudzuhn, Ifey Alio, Raphael Moll, Jessica de Vries, Gordon Jacob Boehlich, Maik Assmann, Jasmin Janneschütz, Nina Schützenmeister , Axel Himmelbach, Anja Poehlein, Rolf Daniel, Wolfgang R. Streit Microbiology Spectrum 10, e0258221 (13 pp) (2022) |
| 88 |
Natural Product-Derived Phosphonic Acids as Corrosion Inhibitors for Iron and Steel Erik Ruf, Tim Naundorf, Tom Seddig, Helmut Kipphardt, Wolfgang Maison Molecules 27, 1778 (17 pp) (2022) |
| 87 |
PKN3: a target in cancer metastasis Louisa Temme , Tuomo Laitinen, Christopher R. M. Asquith Nature Reviews Drug Discovery 21, 704 (1 pp) (2022) |
| 86 |
A Machine Learning Approach to Predict Interdose Vancomycin Exposure Mehdi Bououda, David W. Uster, Egor Sidorov, Marc Labriffe, Pierre Marquet, Sebastian G. Wicha , Jean-Baptiste Woillard Pharmaceutical Research 39, 721-731 (2022) |
| 85 |
Optimized Rhombic Experimental Dynamic Checkerboard Designs to Elucidate Pharmacodynamic Drug Interactions of Antibiotics Niklas Krömer, Romain Aubry, William Couet, Nicolas Grégoire, Sebastian G. Wicha Pharmaceutical Research 39, 3267-3277 (2022) |
| 84 |
Ciprofloxacin in Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): A Population Pharmacokinetic Study Dzenefa Alihodzic, Sebastian G. Wicha , Otto R. Frey, Christina König, Michael Baehr, Dominik Jarczak, Stefan Kluge, Claudia Langebrake Pharmaceutics 14, 965 (15 pp) (2022) |
| 83 |
Population Pharmacokinetics of Busulfan and Its Metabolite Sulfolane in Patients with Myelofibrosis Undergoing Hematopoietic Stem Cell Transplantation Adrin Dadkhah, Sebastian G. Wicha , Nicolaus Kröger , Alexander Müller, Christoph Pfaffendorf, Maria Riedner , Anita Badbaran, Boris Fehse, Claudia Langebrake Pharmaceutics 14, 1145 (13 pp) (2022) |
| 82 |
Systematic Comparison of Hospital-Wide Standard and Model-Based Therapeutic Drug Monitoring of Vancomycin in Adults Heleen Gastmans, Erwin Dreesen, Sebastian G. Wicha , Nada Dia, Ellen Spreuwers, Annabel Dompas, Karel Allegaert, Stefanie Desmet, Katrien Lagrou, Willy E. Peetermans, Yves Debaveye, Isabel Spriet, Matthias Gijsen Pharmaceutics 14, 1459 (13 pp) (2022) |
| 81 |
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin Lina Keutzer, Huifang You, Ali Farnoud, Joakim Nyberg, Sebastian G. Wicha , Gareth Maher-Edwards, Georgios Vlasakakis, Gita Khalili Moghaddam, Elin M. Svensson, Michael P. Menden, Ulrika S. H. Simonsson Pharmaceutics 14, 1530 (29 pp) (2022) |
| 80 |
A Novel Two-Chamber Setup for Containment Investigations with Special Focus on the Dustiness of Pharmaceutical Powders Depending on the Airflow Steffen Wirth, Martin Schöler, Jonas Brügmann, Claudia S. Leopold Pharmaceutics 14, 2387 (19 pp) (2022) |
| 79 |
Optimized isolation of 7,7'-biphyscion starting from Cortinarius rubrophyllus, a chemically unexplored fungal species rich in photosensitizers Fabian Hammerle, Lisa-Maria Steger, Xuequan Zhou, Sylvestre Bonnet, Lesley Huymann, Ursula Peintner, Bianka Siewert Photochemical & Photobiological Sciences 21, 221-234 (2022) |
| 78 |
Photochemical defense as trait of fungi from Cortinarius subgenus Dermocybe Anna Hannecker, Lesley Huymann, Fabian Hammerle, Ursula Peintner, Bianka Siewert Photochemical & Photobiological Sciences 22, 147-147 (2022) |
| 77 |
Liver function, quantified by the LiMAx test, as a predictor for the clinical outcome of critically ill patients treated with linezolid Rawana Alraish, Sebastian G. Wicha , Otto R. Frey, Anka Roehr, Johanna Pratschke, Martina Stockmann, Tiloa Wuensch, Magnusa Kaffarnik Technology and Health Care 30, 309-321 (2022) |
| 76 |
Dosing for Personalized Prophylaxis in Hemophilia A Highly Varies on the Underlying Population Pharmacokinetic Models David W. Uster, Pratima Chowdary, Anne Riddell, Cecilia Garcia, Elsa Aradom, Molly Musarara, Sebastian G. Wicha Therapeutic Drug Monitoring 44, 665-673 (2022) |
| 75 |
Brustkrebsfrüherkennung: Ein Beitrag zur Frage, ob die Altersgrenzen des Mammographie-Screening-Programms in Deutschland ausgeweitet werden sollten Dagmar Hertle, Danny Wende, Claudia Schulte, Ingrid Mühlhauser bifg ePaper (2022) |
| 74 |
Menopausale
Hormontherapie: Evidenz und Eingang in die Praxis Ingrid Mühlhauser, Maria Beckermann -/- Herausgeber: Helmut Schröder, Petra Thürmann, Carsten Telschow, Melanie Schröder, Reinhard Busse Arzneimittel-Kompass 2022. Qualität der Arzneimittelversorgung 113-129 (2022), Verlag: Springer Verlag (open access) |
| 73 |
Seltene Pilzfunde aus dem norddeutschen Raum Wulf Schultze Berichte des Botanischen Vereins zu Hamburg 33, 31-59 (2022) |
| 72 |
Wissenschaftsleugnung - ein Kommentar aus Sicht der Evidenzbasierten Medizin [reprint] Ingrid Mühlhauser -/- Herausgeber: Wilfried von Eiff, Herbert Rebscher Krisenresilenz - Wie Corona das Krisenmanagement des Gesundheitssystems verändert 19-29 (2022), ISBN 978-3-86216-910-8 , Verlag: medhochzwei Verlag, Heidelberg |
2021 | |
| 71 |
X-ray-Based Techniques to Study the Nano-Bio Interface Carlos Sanchez-Cano, Ramón A. Alvarez-Puebla, John M. Abendroth, Tobias Beck , Robert H. Blick , Yuan Cao, Frank Caruso, Indranath Chakraborty, Henry N. Chapman , Chunying Chen, Bruce E. Cohen, Andre L. C. Conceição, David P. Cormode, Daxiang Cui, Kenneth A. Dawson, Gerald Falkenberg, Chunhai Fan, Neus Feliu , Mingyuan Gao, Elisabetta Gargioni, Claus-C. Glüer, Florian Grüner , Moustapha Hassan, Yong Hu, Yalan Huang, Samuel Huber , Nils Huse , Yanan Kang, Ali Khademhosseini, Thomas F. Keller, Christian Körnig, Nicholas A. Kotov, Dorota Koziej , Xing-Jie Liang, Beibei Liu, Sijin Liu, Yang Liu, Ziyao Liu, Luis M. Liz-Marzán, Xiaowei Ma, Andres Machicote, Wolfgang Maison , Adrian P. Mancuso, Saad Megahed, Bert Nickel, Ferdinand Otto, Cristina Palencia, Sakura Pascarelli, Arwen R. Pearson , Oula Peñate-Medina, Bing Qi, Joachim O. Rädler , Joseph J. Richardson, Axel Rosenhahn, Kai Rothkamm, Michael Rübhausen , Milan K. Sanyal, Raymond E. Schaak, Heinz-Peter Schlemmer, Marius Schmidt, Oliver Schmutzler, Theo Schotten, Florian Schulz , Ajay K. Sood, Kathryn M. Spiers, Theresa Staufer, Dominik M. Stemer , Andreas Stierle , Xing Sun, Gohar Tsakanova, Paul S. Weiss, Horst Weller , Fabian Westermeier, Ming Xu, Huijie Yan, Yuan Zeng, Ying Zhao, Yuliang Zhao, Dingcheng Zhu, Ying Zhu, Wolfgang J. Parak ACS Nano 15, 3754-3807 (2021) |
| 70 |
Antibacterial activity of xylose-derived LpxC inhibitors - Synthesis, biological evaluation and molecular docking studies Alexander Dreger, Katharina Hoff, Oriana Agoglitta, Sven-Kevin Hotop, Mark Brönstrup, Peter Heisig, Johannes Kirchmair , Ralph Holl Bioorganic Chemistry 107, 104603 (15 pp) (2021) |
| 69 |
Regulation of dual leucine zipper kinase activity through its interaction with calcineurin Jorge Duque Escobar, Anna Kutschenko, Sabine Schröder, Roland Blume, Kyra-Alexandra Köster, Christina Painer, Thomas Lemcke, Wolfgang Maison , Elke Oetjen Cellular Signalling 82, 109953 (2021) |
| 68 |
Targeted Isolation of Photoactive Pigments from Mushrooms Yielded a Highly Potent New Photosensitizer: 7,7'-Biphyscion Fabian Hammerle, Isabella Bingger, Andrea Pannwitz, Alexander Magnutzki, Ronald Gstir, Adriano Rutz, Jean-Luc Wolfender, Ursula Peintner, Bianka Siewert ChemRxiv 13721770.v1 (2021) |
| 67 |
Towards precision dosing of vancomycin in critically ill patients: an evaluation of the predictive performance of pharmacometric models in ICU patients Christopher B. Cunio, David W. Uster, Jane E. Carland, Hergen Buscher, Zhixen Liu, Jonathan Brett, Maurizio Stefani, Graham R. D. Jones, Richard O. Day, Sebastian G. Wicha , Sophie L. Stocker Clinical Microbiology and Infection 27, 783.E7-783.E14 (2021) |
| 66 |
A Model Averaging/Selection Approach Improves the Predictive Performance of Model-Informed Precision Dosing: Vancomycin as a Case Study David W. Uster, Sophie L. Stocker, Jane E. Carland, Jonathan Brett, Deborah J. E. Marriott, Richard O. Day, Sebastian G. Wicha Clinical Pharmacology & Therapeutics 109, 175-183 (2021) |
| 65 |
From Therapeutic Drug Monitoring to Model-Informed Precision Dosing for Antibiotics Sebastian G. Wicha , Anne-Grete Märtson, Elisabet I. Nielsen, Birgit C. P. Koch, Lena E. Friberg, Jan-Willem C. Alffenaar, Iris K. Minichmayr Clinical Pharmacology & Therapeutics 109, 928-941 (2021) |
| 64 |
Nachruf: Professor Dr. Karl-Heinz Kubeczka verstorben Deutsche Apotheker Zeitung 161, 4046-4047 (2021) |
| 63 |
Stability studies with tigecycline in bacterial growth medium and impact of stabilizing agents Lisa F. Amann, Emilia Ruda Vicente, Mareike Rathke, Astrid Broeker, Maria Riedner , Sebastian G. Wicha European Journal of Clinical Microbiology & Infectious Diseases 40, 215-218 (2021) |
| 62 |
Population Pharmacokinetics of PEGylated Asparaginase in Children with Acute Lymphoblastic Leukemia: Treatment Phase Dependency and Predictivity in Case of Missing Data Gudrun Würthwein, Claudia Lanvers-Kaminsky, Christian Siebel, Joachim Gerß, Anja Möricke, Martin Zimmermann, Jan Stary, Petr Smisek, Martin Schrappe, Carmelo Rizzari, Massimo Zucchetti, Georg Hempel, Sebastian G. Wicha , Joachim Boos European Journal of Drug Metabolism and Pharmacokinetics 46, 289-300 (2021) |
| 61 |
Synthesis of Natural Rubrolides B, I, K, L, M, O and Analogues Jessica de Vries, Maik Assmann, Jasmin Janneschütz, Judith Krauß, Mirja Gudzuhn, Stephanie Stanelle-Bertram, Gülsah Gabriel, Wolfgang R. Streit, Nina Schützenmeister European Journal of Organic Chemistry 4195-4200 (2021) Reprint: YourJOCTalents (2021) |
| 60 |
A new High-Throughput-Screening-assay for Photoantimicrobials Based on EUCAST Revealed Photoantimicrobials in Cortinariaceae Johannes Fiala, Harald Schöbel, Pamela Vrabl, Dorothea Dietrich, Fabian Hammerle, Desirée Josefine Altmann, Ronald Stärz, Ursula Peintner, Bianka Siewert Frontiers in Microbiology 12, 703544 (16 pp) (2021) Reprint: bioRxiv 2021.04.02.438202 (2021) |
| 59 |
In vivo / in vitro Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model Matthias G. Vossen, S. Pferschy, C. Milacek, M. Haidinger, Mario Karolyi, Zoltan Vass, Heinz Burgmann, Alexandra Maier-Salamon, Sebastian G. Wicha , Walter Jäger, Markus Zeitlinger, Thomas Stimpf, Thomas Wittek, Florian Thalhammer Frontiers in Pharmacology 12, 702455 (8 pp) (2021) |
| 58 |
Comparison of two empirical prolonged infusion dosing regimens for meropenem in patients with septic shock: A two-center pilot study Albrecht Eisert, Christian Lanckohr, Janina Freyd, Otto Freye, Sebastian G. Wicha , Dagmar Horn, Bjoern Ellger, Tobias Schürholz, Gernot Marx, Tim-Philipp Simon International Journal of Antimicrobial Agents 57, 106289 (8 pp) (2021) |
| 57 |
Assessment of cefepime toxico-dynamics: comprehensive examination of pharmacokinetic?/pharmacodynamic targets for cefepime-induced neurotoxicity and evaluation of current dosing guidelines Cindy Lau, Deborah Marriott, Hayley B. Schultz, Michael Gould, David Andresen, Sebastian G. Wicha , Jan-Willem Alffenaar, Jonathan Penm, Stephanie E. Reuter International Journal of Antimicrobial Agents 58, 106443 (2021) |
| 56 |
Assessment of cefepime toxicodynamics: comprehensive examination of pharmacokinetic/pharmacodynamic targets for cefepime-induced neurotoxicity and evaluation of current dosing guidelines Cindy Lau, Deborah Marriott, Hayley B. Schultz, Michael Gould, David Andresen, Sebastian G. Wicha , Jan-Willem Alffenaar, Jonathan Penm, Stephanie E. Reuter International Journal of Antimicrobial Agents 58, 106443 (2021) |
| 55 |
Application of Aquasolv Lignin in ibuprofen-loaded pharmaceutical formulations obtained via direct compression and wet granulation Joana Gil-Chávez, Sidhant Satya Prakash Padhi, Claudia S. Leopold , Irina Smirnova International Journal of Biological Macromolecules 174, 229-239 (2021) |
| 54 |
X-ray Fluorescence Uptake Measurement of Functionalized Gold Nanoparticles in Tumor Cell Microsamples Oliver Schmutzler, Sebastian Graf, Nils Behm, Wael Y. Mansour , Florian Blumendorf, Theresa Staufer, Christian Körnig, Dina Salah, Yanan Kang, Jan N. Peters, Yang Liu, Neus Feliu , Wolfgang J. Parak , Anja Burkhardt, Elisabetta Gargioni, Sabrina Gennis, Sharah Chandralingam, Finn Höeg, Wolfgang Maison , Kai Rothkamm, Florian Schulz , Florian Grüner International Journal of Molecular Sciences 22, 3691 (13 pp) (2021) |
| 53 |
Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers Beatrix Wulkersdorfer, Sebastian G. Wicha , Elizaveta Kurdina, Stephan F. Carrion Carrera, Peter Matzneller, Valentin Al Jalali, Matthias G. Vossen, Sonja Riesenhuber, Edith Lackner, Christoph Dorn, Markus Zeitlinger Journal of Antimicrobial Chemotherapy 76, 2106-2113 (2021) |
| 52 |
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes Benjamin J. Eduful, Sean N. O'Byrne, Louisa Temme , Christopher R. M. Asquith , Yi Liang, Alfredo Picado, Joseph R. Pilotte, Mohammad Anwar Hossain, Carrow I. Wells, William J. Zuercher, Carolina M. C. Catta-Preta, Priscila Zonzini Ramos, André de S. Santiago, Rafael M. Couñago, Christopher G. Langendorf, Kévin Nay, Jonathan S. Oakhill, Thomas L. Pulliam, Chenchu Lin, Dominik Awad, Timothy M. Willson, Daniel E. Frigo, John W. Scott, David H. Drewry Journal of Medicinal Chemistry 64, 10849-10877 (2021) |
| 51 |
Mehr Frauen als Männer versterben an kardiovaskulären Erkrankungen (?). Die Interpretation statistischer Daten erfordert faire und verständliche Vergleiche Ingrid Mühlhauser KVH-Journal (4) 22-25 (2021) |
| 50 |
Vitamin D - das Ende eines Hypes? Screening auf Vitamin-D-Mangel ohne Nutzennachweis Ingrid Mühlhauser KVH-Journal (7-8) 22-24 (2021) |
| 49 |
Blutdruckzielwerte für die Hypertoniebehandlung Ingrid Mühlhauser KVH-Journal (11) 26-30 (2021) |
| 48 |
Feature-Based Molecular Networking - An Exciting Tool to Spot Species of the Genus Cortinarius with Hidden Photosensitizers Fabian Hammerle, Luis Quirós-Guerrero, Adriano Rutz, Jean-Luc Wolfender, Harald Schöbel, Ursula Peintner, Bianka Siewert Metabolites 11, 791 (20 pp) (2021) |
| 47 |
Voriconazole Pharmacokinetics Are Not Altered in Critically Ill Patients with Acute-on-Chronic Liver Failure and Continuous Renal Replacement Therapy: An Observational Study Jörn Grensemann, Christoph Pfaffendorf, Sebastian G. Wicha , Christina König, Kevin Roedl, Dominik Jarczak, Stefanie Iwersen-Bergmann, Carolin Manthey, Stefan Kluge, Valentin Fuhrmann Microorganisms 9, 2087 (13 pp) (2021) |
| 46 |
eEF2K: an atypical kinase target for cancer Louisa Temme , Christopher R. M. Asquith Nature Reviews Drug Discovery 20, 577 (1 pp) (2021) |
| 45 |
Synthesis and application of a thiol-reactive HBED-type chelator for development of easy-to-produce Ga-radiopharmaceutical kits and imaging probes Karel D. Klika, Chiara da Pieve, Klaus Kopka, Graham Smith, Ata Makarem Organic & Biomolecular Chemistry 19, 1722-1726 (2021) |
| 44 |
Pulmonary drug delivery with aerogels: engineering of alginate and alginate-hyaluronic acid microspheres Tamara Athamneh, Adil Amin, Edit Benke, Rita Ambrus, Pavel Gurikov, Irina Smirnova, Claudia S. Leopold Pharmaceutical Development and Technology 26, 509-521 (2021) |
| 43 |
Evaluation of the Robustness of Therapeutic Drug Monitoring Coupled with Bayesian Forecasting of Busulfan with Regard to Inaccurate Documentation Adrin Dadkhah, Dzenefa Alihodzic, Astrid Broeker, Nicolaus Kröger , Claudia Langebrake, Sebastian G. Wicha Pharmaceutical Research 38, 1721-1729 (2021) |
| 42 |
A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice Sebastian Franck, Robin Michelet, Fiordiligie Casilag, Jean-Claude Sirard, Sebastian G. Wicha , Charlotte Kloft Pharmaceutics 13, 469 (11 pp) (2021) |
| 41 |
The
Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia Robin Michelet, Moreno Ursino, Sandrine Boulet, Sebastian Franck, Fiordiligie Casilag, Mara Baldry, Jens Rolff, Madelé van Dyk, Sebastian G. Wicha , Jean-Claude Sirard, Emmanuelle Comets, Sarah Zohar, Charlotte Kloft Pharmaceutics 13, 601 (12 pp) (2021) |
| 40 |
Professor Dr. Karl-Heinz Kubeczka verstorben Elisabeth Stahl-Biskup Pharmazeutische Zeitung 166, 3331-3332 (2021) |
| 39 |
Does the chemistry of fungal pigments demand the existence of photoactivated defense strategies in basidiomycetes? Bianka Siewert Photochemical & Photobiological Sciences 20, 475-488 (2021) |
| 38 |
Evaluation of the orally administered calcium alginate aerogel on the changes of gut microbiota and hepatic and renal function of Wistar rats Mohammad A. A. Al-Najjar, Tamara Athamneh, Reem AbuTayeh, Iman Basheti, Claudia S. Leopold , Pavel Gurikov, Irina Smirnova PLoS One 16, e0247633 (18 pp) (2021) |
| 37 |
Determination of Tedizolid in Bacterial Growth Medium Mueller-Hinton Broth by High-Performance Liquid Chromatography and Its Application to an In Vitro Study in the Hollow-Fiber Infection Model Khalid Iqbal, Aliki Milioudi, Elena Haro Martinez, Sebastian G. Wicha Separations 8, 141 (9 pp) (2021) |
| 36 |
A simple but unusual rearrangement of an oleanane to a taraxerane-28,14 β-olide Niels Heise, Bianka Siewert , Dieter Ströhl, Sophie Hoenke, Oxana Kazakova, René Csuk Steroids 172, 108853 (5 pp) (2021) |
| 35 |
Wissenschaftsleugnung - ein Kommentar aus Sicht der Evidentbasierten Medizin Ingrid Mühlhauser Ärtzeblatt Sachsen 32 (9) 27-31 (2021) Reprint: Ärtzeblatt Sachsen 32 (9) Literaturverzeichnis zum Artikel (2021) ; Reprint: KVH-Journal (10) 14-21 (2021) ; Reprint: Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen 166, 79-83 (2021) ; Reprint: Welt der Krankenversicherung 11, 208-212 (2022) |
| 34 |
Untersuchung einiger norddeutscher Vorkommen der Haarsimse (Trichophorum) Wulf Schultze Berichte des Botanischen Vereins zu Hamburg 32, 35-43 (2021) |
| 33 |
Amino acids as green neutralizing agent for acidic corrosion inhibitors Helmut Kipphardt, Tim Naundorf, Erik Ruf, Wolfgang Maison -/- Anmelder: Metall-Chemie Technologies GmbH Patent: WO 2021165311 (A1) 2021-08-26 |
| 32 |
Phosphonic acids based on natural substances as acidic corrosion inhibitors (Naturstoffbasierte Phosphonsäuren als saure Korrosionsinhibitoren ) Erik Ruf, Tim Naundorf, Helmut Kipphardt, Wolfgang Maison -/- Anmelder: Metall-Chemie Technologies GmbH Patent: WO 2021165313 (A1) 2021-08-26; DE 102020104085 (A1) 2021-08-19 |
2020 | |
| 31 |
Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx) Rawan Alraish, Sebastian G. Wicha , Otto R. Frey, Anka C. Röhr, Johann Pratschke, Martin Stockmann, Tilo Wuensch, Magnus Kaffarnik Annals of Intensive Care 10, 106 (9 pp) (2020) |
| 30 |
Synthesis, characterization and evaluation of 68Ga labelled monomeric and dimeric quinazoline derivatives of the HBED-CC chelator targeting the epidermal growth factor receptor Christos Liolios, Antonio Shegani, Ioanna Roupa, Christos Kiritsis, Ata Makarem , Maria Paravatou-Petsotas, Maria Pelecanou, Penelope Bouziotis, Minas Papadopoulos, Klaus Kopka, Ioannis Pirmettis Bioorganic Chemistry 100, 103855 (9 pp) (2020) |
| 29 |
Total Synthesis of Anti-MRSA Active Diorcinols and Analogues Gordon Jacob Boehlich, Jessica de Vries, Olivia Geismar, Mirja Gudzuhn, Wolfgang R. Streit, Sebastian G. Wicha , Nina Schützenmeister Chemistry - A European Journal 26, 9846-9850 (2020) Reprint: Young Chemists (2020) |
| 28 |
How to design a study to evaluate therapeutic drug monitoring in infectious diseases? Anne-Grete Märtson, Marieke G. G. Sturkenboom, Jana Stojanova, Dario Cattaneo, William Hope, Debbie Marriott, Asad E. Patanwala, Charles A. Peloquin, Sebastian G. Wicha , Tjip S. van der Werf, Thomas Tängdén, Jason A. Roberts, Michael N. Neely, Jan-Willem C. Alffenaar Clinical Microbiology and Infection 26, 1008-1016 (2020) |
| 27 |
A pharmacometric approach to define target site-specific breakpoints for bacterial killing and resistance suppression integrating microdialysis, time-kill curves and heteroresistance data: A case study with moxifloxacin Khalid Iqbal, Astrid Broeker, Hartmut Nowak, Tim Rahmel, Alina Nussbaumer-Pröll, Zoe Österreicher, Markus Zeitlinger, Sebastian G. Wicha Clinical Microbiology and Infection 26, 1255.e1-1255.e8 (2020) |
| 26 |
Translational Model-Informed Approach for Selection of Tuberculosis Drug Combination Regimens in Early Clinical Development Budi O. Susanto, Sebastian G. Wicha , Yanmin Hu, Anthony R. M. Coates, Ulrika S. H. Simonsson Clinical Pharmacology & Therapeutics 108, 274-286 (2020) |
| 25 |
Contact-active antibacterial polyethylene foils via atmospheric air plasma induced polymerisation of quaternary ammonium salts Serge Kliewer, Sebastian G. Wicha , Astrid Broeker, Tim Naundorf, Tugba Catmadim, Eva Katharina Oellingrath, Marcus Rohnke, Wolfgang R. Streit, Christel Vollstedt, Helmut Kipphardt, Wolfgang Maison Colloids and Surfaces, B: Biointerfaces 186, 110679 (7 pp) (2020) |
| 24 |
Therapeutisches Drug Monitoring von Antiinfektiva bei Intensivpatienten - für welche Arzneistoffe und wie? (Therapeutic drug monitoring of antiinfectives in intensive care unit patients - what's new? Christina König, Stefan Kluge, Sebastian G. Wicha Deutsche Medizinische Wochenschrift 145, 1764-1769 (2020) |
| 23 |
Stabilizing and destabilizing effects of drug-excipient interactions in spray-dried, freeze-dried, and granulated Sennae fructus extracts Kira-Isabel Zier, Wulf Schultze, Uta Sazama, Michael Fröba , Claudia S. Leopold Drying Technology 38, 1882-1890 (2020) |
| 22 |
Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds Louisa Temme , Elena Bechthold, Julian A. Schreiber, Sandeep Gawaskar, Dirk Schepmann, Dina Robaa, Wolfgang Sippl, Guiscard Seebohm, Bernhard Wünsch European Journal of Medicinal Chemistry 190, 112138 (2020) |
| 21 |
Impact of Inaccurate Documentation of Sampling and Infusion Time in Model-Informed Precision Dosing Dzenefa Alihodzic, Astrid Broeker, Michael Baehr, Stefan Kluge, Claudia Langebrake, Sebastian G. Wicha Frontiers in Pharmacology 11, 172 (12 pp) (2020) |
| 20 |
Saliva for Precision Dosing of Antifungal Drugs: Saliva Population PK Model for Voriconazole Based on a Systematic Review Hannah Yejin Kim, Anne-Grete Märtson, Erwin Dreesen, Isabel Spriet, Sebastian G. Wicha , Andrew J. McLachlan, Jan-Willem C. Alffenaar Frontiers in Pharmacology 11, 894 (15 pp) (2020) |
| 19 |
Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper Mohd H. Abdul-Aziz, Jan-Willem C. Alffenaar, Matteo Bassetti, Hendrik Bracht, George Dimopoulos, Deborah Marriott, Michael N. Neely, Jose-Artur Paiva, Federico Pea, Fredrik Sjovall, Jean F. Timsit, Andrew A. Udy, Sebastian G. Wicha , Markus Zeitlinger, Jan J. De Waele, Jason A. Roberts Intensive Care Medicine 46, 1127-1153 (2020) |
| 18 |
A novel approach to avoid capping and/or lamination by application of external lower punch vibration Alexander Kalies, Thomas Heinrich, Claudia S. Leopold International Journal of Pharmaceutics 580, 119195 (2020) |
| 17 |
Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review Lina Keutzer, Sebastian G. Wicha , Ulrika S. H. Simonsson JMIR mHealth and uHealth 8 (4) e17246 (2020) |
| 16 |
Pharmacokinetics of trimethoprim/sulfametrole in critically ill patients on continuous renal replacement therapy René Welte, Rudolph Beyer, Johannes Hotter, Astrid Broeker, Sebastian G. Wicha , Tiziana Gasperetti, Paul Ranke, Marc-Michael Zaruba, Ingo Lorenz, Stephan Eschertzhuber, Mathias Ströhle, Rosa Bellmann-Weiler, Michael Joannidis, Romuald Bellmann Journal of Antimicrobial Chemotherapy 75, 1237-1241 (2020) |
| 15 |
Effect of Pullulan as Additive to the Synthetic Polymeric Coating Blend Eudragit NM-L55 on the Properties of the Resulting Films Pirijanka Sriganaranjan, Claudia S. Leopold Journal of Pharmaceutical Sciences 109, 2166-2172 (2020) |
| 14 |
Assessing parameter uncertainty in small-n pharmacometric analyses: value of the log-likelihood profiling-based sampling importance resampling (LLP-SIR) technique Astrid Broeker, Sebastian G. Wicha Journal of Pharmacokinetics and Pharmacodynamics 47, 219-228 (2020) |
| 13 |
Werden ältere Menschen benachteiligt, wenn Screening-Programme altersbegrenzt sind? Wie der Nutzen von Krebsfrüherkennung von Alter und Gesundheitszustand abhängt Ingrid Mühlhauser KVH-Journal (3) 22-25 (2020) |
| 12 |
Unerwünschte Wirkungen von Präventionsmaßnahmen - die Bedeutung von Kollateraleffekten Ingrid Mühlhauser KVH-Journal (4) 30-33 (2020) |
| 11 |
Risikokommunikation zu Covid-19 in den Medien Ingrid Mühlhauser KVH-Journal (10) 26-29 (2020) |
| 10 |
Risikokommunikation von COVID-19-Mortalitätsdaten Ingrid Mühlhauser KVH-Journal (12) 28-31 (2020) |
| 9 |
The cytotoxicity of brazilin and derivatives might be due to an inhibition of the c-Src-kinase Annemarie E. Kramell, Bianka Siewert , Jana Wiese, Veronika Temml, Hans-Peter Deigner, Ahmed Al-Harrasi, René Csuk Mediterranean Journal of Chemistry 10, 790-798 (2020) |
| 8 |
Thiol-Reactive PODS-Bearing Bifunctional Chelators for the Development of EGFR-Targeting [18F]AlF-Affibody Conjugates Chiara da Pieve, Ata Makarem , Stephen Turnock, Justyna Maczynska, Graham Smith, Gabriela Kramer-Marek Molecules 25, 1562 (12 pp) (2020) |
| 7 |
STK19: a new target for NRAS-driven cancer Christopher R. M. Asquith , Louisa Temme Nature Reviews Drug Discovery 19, 579 (1 pp) (2020) |
| 6 |
An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy Astrid Broeker, Matthias G. Vossen, Florian Thalhammer, Steven C. Wallis, Jeffrey Lipman, Jason A. Roberts, Sebastian G. Wicha Pharmaceutical Research 37, 96 (15 pp) (2020) |
| 5 |
Towards a Quantitative Mechanistic Understanding of Localized Pulmonary Tissue Retention-A Combined In Vivo/In Silico Approach Based on Four Model Drugs Anneke Himstedt, Clemens Braun, Sebastian G. Wicha , Jens Markus Borghardt Pharmaceutics 12, 408 (20 pp) (2020) |
| 4 |
Bacterial Resistance to Antibiotics Anke Heisig, Peter Heisig -/- Herausgeber: Stefan Offermanns, Walter Rosenthal Encyclopedia of Molecular Pharmacology Online: 01 June 2020 (17 pp) (2020) |
| 3 |
Unerwünschte Wirkungen von Präventionsmaßnahmen - kein Thema der Präventionsberichterstattung? Ein kritischer Kommentar Ingrid Mühlhauser -/- Herausgeber: Robert-Koch-Institut Gesundheitsberichterstattung des Bundes gemeinsam getragen von RKI und DESTATIS. Über Prävention berichten - aber wie? Methodenprobleme der Präventionsberichterstattung 117-123 (2020) |
| 2 |
Synthesis of amines by pericyclic reactions involving C=N units (update 2020) Wolfgang Maison Science of Synthesis, Knowledge Updates (1) 397-424 (2020) |
| 1 |
Contact-active antibacterial polymeric materials Helmut Kipphardt, Wolfgang Maison , Serge Kliewer -/- Anmelder: Universität Hamburg Patent: WO 2020169828 (A1) 2020-08-27 |