Department of Chemestry
Publications by Elke Oetjen
.
| Search: Chemistry Dep. / all Hamburg | |
| 2024 | |
| 54 |
Regulation of the Activity of the Dual Leucine Zipper Kinase by Distinct Mechanisms Kyra-Alexandra Köster, Marten Dethlefs, Jorge Duque Escobar, Elke Oetjen Cells 13, 333 (2024) |
| 53 |
Iodinated PSMA Ligands as XFI Tracers for Targeted Cell Imaging and Characterization of Nanoparticles Svenja Kerpa, Malte Holzapfel, Theresa Staufer, Robert Kuhrwahl, Marina Mutas, Stefan Werner, Verena R. Schulze, Pascal Nakielski, Neus Feliu , Elke Oetjen , Jannis Haak, Florian Ziegler, Rasmus Buchin, Jili Han, Wolfgang J. Parak , Florian Grüner , Wolfgang Maison International Journal of Molecular Sciences 25, 11880 (13 pp) (2024) |
2023 | |
| 52 |
Increase of c-FOS promoter transcriptional activity by the dual leucine zipper kinase Kyra-Alexandra Köster, Jorge Duque Escobar, Anja Fietkau, Regina Toledo, Elke Oetjen Naunyn-Schmiedeberg's Archives of Pharmacology 396, 1223-1233 (2023) |
2021 | |
| 51 |
Regulation of dual leucine zipper kinase activity through its interaction with calcineurin Jorge Duque Escobar, Anna Kutschenko, Sabine Schröder, Roland Blume, Kyra-Alexandra Köster, Christina Painer, Thomas Lemcke, Wolfgang Maison , Elke Oetjen Cellular Signalling 82, 109953 (2021) |
2019 | |
| 50 |
Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy Karoline Morhenn, Thomas Quentin, Helen Wichmann, Michael Steinmetz, Maksymilian Prondzynski, Klaus-Dieter Söhren, Torsten Christ, Birgit Geertz, Sabine Schröder, Friedrich A. Schöndube, Gerd Hasenfuss, Saskia Schlossarek, Wolfram-Hubertus Zimmermann, Lucie Carrier , Thomas Eschenhagen, Jean-René Cardinaux, Susanne Lutz, Elke Oetjen Journal of Molecular and Cellular Cardiology 127, 31-43 (2019) |
2017 | |
| 49 |
Endothelial cells regulate β-catenin activity in adrenocortical cells via secretion of basic fibroblast growth factor Carolin Schwafertz, Sven Schinner, Markus C. Kühn, Matthias Haase, Amelie Asmus, Birgit Mülders-Opgenoorth, Ishrath Ansurudeen, Peter J. Hornsby, Henning Morawietz, Elke Oetjen , Matthias Schott, Holger S. Willenberg Molecular and Cellular Endocrinology 441, 108-115 (2017) |
| 48 |
TNFα-induced DLK activation contributes to apoptosis in the β-cell line HIT Svenja Börchers, Rohollah Babaei, Catarina Klimpel, Jorge Enrique Duque Escobar, Sabine Schröder, Roland Blume, Muhammad Nasir Hayat Malik, Elke Oetjen Naunyn-Schmiedeberg's Archives of Pharmacology 90, 813-825 (2017) |
2016 | |
| 47 |
Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase Elke Oetjen Archiv der Pharmazie 349, 410-413 (2016) |
| 46 |
Distinct functions of the dual leucine zipper kinase depending on its subcellular localization Manuel Wallbach, Jorge Enrique Duque Escobar, Rohollah Babaeikelishomi, Marie-Jeannette Stahnke, Roland Blume, Sabine Schröder, Jenny Kruegel, Kathrin Maedler, Oliver Kluth, Ralph H. Kehlenbach, Nicolai Miosge, Elke Oetjen Cellular Signalling 28, 272-283 (2016) |
| 45 |
Dual leucine zipper kinase (MAP3K12) modulators: a patent review (2010-2015) Elke Oetjen , Thomas Lemcke Expert Opinion on Therapeutic Patents 26, 607-616 (2016) |
2014 | |
| 44 |
Something old, something new and something very old: drugs for treating type 2 diabetes Diana Kaiser, Elke Oetjen British Journal of Pharmacology 171, 2940-2950 (2014) |
| 43 |
Inhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinase Marie-Jeannette Stahnke, Corinna Dickel, Sabine Schröder, Diana Kaiser, Roland Blume, Roland Stein, Celio Pouponnot, Elke Oetjen Cellular Signalling 26, 1792-1799 (2014) |
2013 | |
| 42 |
Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP - Implications for CREB-dependent gene transcription Annette Heinrich, Anne Sophie von der Heyde, Ulrike Böer, Do Thanh Phu, Mladen V. Tzvetkov, Elke Oetjen Cellular Signalling 25, 113-125 (2013) |
| 41 |
Hypothalamische und hypophysäre Hormone Hans Jürgen Steinfelder, Elke Oetjen Allgemeine und spezielle Pharmakologie und Toxikologie. 11. Auflage 611-630 (2013), Publisher: Elsevier, München |
| 40 |
Nebennierenrindenhormone Elke Oetjen , Hans Jürgen Steinfelder Allgemeine und spezielle Pharmakologie und Toxikologie. 11. Auflage 631-652 (2013), Publisher: Elsevier, München |
2012 | |
| 39 |
Orale Antidiabetika (Oral antidiabetic drugs) Elke Oetjen Der Kardiologe 6, 467-473 (2012) |
| 38 |
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes Elke Oetjen Yearbook of Endocrinology 13-13 (2012) |
| 37 |
Body Weight, Not Insulin Sensitivity or Secretion, May Predict Spontaneous Weight Changes in Nondiabetic and Prediabetic Subjects: The RISC Study Elke Oetjen Yearbook of Endocrinology 19-19 (2012) |
2011 | |
| 36 |
Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels Do Thanh Phu, Manuel Wallbach, Chantal Depatie, Accalia Fu, Robert A. Screaton, Elke Oetjen Cellular Signalling 23, 344-353 (2011) |
| 35 |
Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression Kai-Martin Thoms, Christiane Kuschal, Elke Oetjen , Toshio Mori, Nobuhiko Kobayashi, Petra Laspe, Lars Boeckmann, Michael P. Schön, Steffen Emmert Experimental Dermatology 20, 232-236 (2011) |
2009 | |
| 34 |
Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC Annette Heinrich, Ulrike Böer, Mladen V. Tzvetkov, Elke Oetjen , Willhart Knepel Bioscience Reports 29, 77-87 (2009) |
| 33 |
Inhibition of human insulin gene transcription by peroxisome proliferator-activated receptor and thiazolidinedione oral antidiabetic drugs Sven Schinner, Ralph Krätzner, Diana Baun, Corinna Dickel, Roland Blume, Elke Oetjen British Journal of Pharmacology 157, 736-745 (2009) |
| 32 |
Translocation of the mitogen-activated triple kinase DLK to the nucleus Manuel Wallbach, Jenny Kruegel, Nicolai Miosge, Elke Oetjen Naunyn-Schmiedeberg's Archives of Pharmacology 379 (Suppl. 1) 28-29 (Abstr. 117) (2009) Alternative Source Name: 50th Annual Meeting. Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie. Mainz, March 10-12, 2009 |
| 31 |
Induction of β-cell apoptosis by the proinflammatory cytokine IL-1β not involving the apoptosis-inducing dual leucine zipper bearing kinase DLK Catarina Klimpel, Svenja Börchers, Elke Oetjen Naunyn-Schmiedeberg's Archives of Pharmacology 379 (Suppl. 1) 37-37 (Abstr. 164) (2009) Alternative Source Name: 50th Annual Meeting. Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie. Mainz, March 10-12, 2009 |
| 30 |
The lithium-induced increase of the interaction between CREB and its coactivator TORC1 is not dependent on lysine 290 of CREB Annette Heinrich, Ulrike Böer, Elke Oetjen , Willhart Knepel Naunyn-Schmiedeberg's Archives of Pharmacology 379 (Suppl. 1) 48-48 (Abstr. 225) (2009) Alternative Source Name: 50th Annual Meeting. Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie. Mainz, March 10-12, 2009 |
| 29 |
The mitogen-activated protein kinase DLK inhibits the CREB co-activator TORC Do Thanh Phu, Elke Oetjen Naunyn-Schmiedeberg's Archives of Pharmacology 379 (Suppl. 1) 59-59 (Abstr. 286) (2009) Alternative Source Name: 50th Annual Meeting. Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie. Mainz, March 10-12, 2009 |
2008 | |
| 28 |
Loss of insulin-induced inhibition of glucagon gene transcription in hamster pancreatic islet α cells by long-term insulin exposure M. González, Ulrike Böer, Corinna Dickel, Thomas Quentin, Irmgard Cierny, Elke Oetjen , Willhart Knepel Diabetologia 51, 2012-2021 (2008) |
| 27 |
A peroxisome proliferator-activated receptor -retinoid X receptor heterodimer physically interacts with the transcriptional activator PAX6 to inhibit glucagon gene transcription Ralph Krätzner, Florian Froehlich, Katrin Lepler, Michaela Schroeder, Katharina Roeher, Corinna Dickel, Mladen V. Tzvetkov, Thomas Quentin, Elke Oetjen , Willhart Knepel Molecular Pharmacology 73, 509-517 (2008) |
| 26 |
Activation of the dual-leucine-zipper-bearing kinase and induction of β-cell apoptosis by the immunosuppressive drug cyclosporin A Silke Plaumann, Roland Blume, Svenja Börchers, Hans Jürgen Steinfelder, Willhart Knepel, Elke Oetjen Molecular Pharmacology 73, 652-659 (2008) |
| 25 |
Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene Cornelia Meineke, Mladen V. Tzvetkov, Kristin Bokelmann, Elke Oetjen , Karen Hirsch-Ernst, Rolf Kaiser, Jürgen Brockmöller Pharmacogenetics and Genomics 18, 219-230 (2008) |
2007 | |
| 24 |
Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1β and mitogen-activated protein kinase kinase kinase in pancreatic islet β cells Elke Oetjen , Roland Blume, Irmgard Cierny, Christoph Schlag , Anna Kutschenko, Ralph Krätzner, Roland Stein, Willhart Knepel Diabetologia 50, 1678-1687 (2007) |
| 23 |
Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine Mladen V. Tzvetkov, Cornelia Meineke, Elke Oetjen , Karen Hirsch-Ernst, Jürgen Brockmöller Gene 386, 52-62 (2007) |
2006 | |
| 22 |
Inhibition of membrane depolarisation-induced transcriptional activity of cyclic AMP response element binding protein (CREB) by the dual-leucine-zipper-bearing kinase in a pancreatic islet β cell line Elke Oetjen , A. Lechleiter, Roland Blume, D. Nihalani, L. Holzman, Willhart Knepel Diabetologia 49, 332-342 (2006) |
| 21 |
The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures Christina Ziemann, Armin Riecke, Gudrun Rüdell, Elke Oetjen , Hans Jürgen Steinfelder, Christian Lass, Georg F. Kahl, Karen I. Hirsch-Ernst Journal of Pharmacology and Experimental Therapeutics 317, 378-386 (2006) |
2005 | |
| 20 |
Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans Sanjeev K. Sharma, Ulrike Leinemann, Regine Ratke, Elke Oetjen , Roland Blume, Corinna Dickel, Willhart Knepel Biochemical Journal 389, 831-841 (2005) |
| 19 |
The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator level Elke Oetjen , Kai-Martin Thoms, Yvonne Laufer, Daniela Pape, Roland Blume, Pingfeng Li, Willhart Knepel British Journal of Pharmacology 144, 982-993 (2005) |
| 18 |
Protein Kinase B Activity Is Sufficient to Mimic the Effect of Insulin on Glucagon Gene Transcription Sven Schinner, Andreas Barthel, Claudia Dellas, Rafal Grzeskowiak, Sanjeev K. Sharma, Elke Oetjen , Roland Blume, Willhart Knepel Journal of Biological Chemistry 280, 7369-7376 (2005) |
2003 | |
| 17 |
Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice Elke Oetjen , Diana Baun, Stephan Beimesche, Doris Krause, Irmgard Cierny, Roland Blume, Corinna Dickel, Simone Wehner, Willhart Knepel Molecular Pharmacology 63, 1289-1295 (2003) |
| 16 |
Regulation
of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB Elke Oetjen , Daniela Grapentin, Roland Blume, Michael Seeger, Doris Krause, Anke Eggers, Willhart Knepel Naunyn-Schmiedeberg's Archives of Pharmacology 367, 227-236 (2003) |
2000 | |
| 15 |
Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6 Rafal Grzeskowiak, Jasmin Amin, Elke Oetjen , Willhart Knepel Journal of Biological Chemistry 275, 30037-30045 (2000) |
1999 | |
| 14 |
The hepatitis B pX protein promotes dimerization and DNA binding of cellular basic region/leucine zipper proteins by targeting the conserved basic region Giovanni Perini, Elke Oetjen , Michael R. Green Journal of Biological Chemistry 274, 13970-13977 (1999) |
| 13 |
Inhibition of cyclic AMP response element-binding protein/cyclic AMP response element-mediated transcription by the immunosuppressive drugs cyclosporin A and FK506 depends on the promoter context Gero Siemann, Roland Blume, Daniela Grapentin, Elke Oetjen , Markus Schwaninger, Willhart Knepel Molecular Pharmacology 55, 1094-1100 (1999) |
| 12 |
Membrane depolarization and cyclic AMP induced transcriptional activity of a CBP fragment in the pancreatic islet cell line HIT Pingfeng Li, Elke Oetjen , Roland Blume, Willhart Knepel Zhongguo Shengwu Huaxue Yu Fenzi Shengwu Xuebao 15, 593-596 (1999) Alternative Source Name: Chinese Journal of Biochemistry and Molecular Biolohy |
| 11 |
The CBP C-terminus activated by cyclic AMP and membrane depolarization in the pancreatic islet cell line HIT Pingfeng Li, Elke Oetjen , Roland Blume, Willhart Knepel Zhongguo Shengwu Huaxue Yu Fenzi Shengwu Xuebao 15, 597-599 (1999) Alternative Source Name: Chinese Journal of Biochemistry and Molecular Biolohy |
1998 | |
| 10 |
Identification and expression of a novel isoform of cAMP response element modulator in the human heart Frank U. Müller, Peter Boknik, Jörg Knapp, Joachim Neumann, Ute Vahlensieck, Elke Oetjen , Hans H. Scheld, Wilhelm Schmitz FASEB Journal 12, 1191-1199 (1998) |
1997 | |
| 9 |
Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells Meike Krüger, Markus Schwaninger, Roland Blume, Elke Oetjen , Willhart Knepel Naunyn-Schmiedeberg's Archives of Pharmacology 356, 433-440 (1997) |
1995 | |
| 8 |
Involvement of the Ca2+-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements Markus Schwaninger, Roland Blume, Meike Krüger, Gundula Lux, Elke Oetjen , Willhart Knepel Journal of Biological Chemistry 270, 8860-8866 (1995) |
1994 | |
| 7 |
Distinct properties of the cAMP-responsive element of the rat insulin I gene Elke Oetjen , Thomas Diedrich, Anke Eggers, Barbara Eckert, Willhart Knepel Journal of Biological Chemistry 269, 27036-27044 (1994) |
1993 | |
| 6 |
Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element Markus Schwaninger, Gundula Lux, Roland Blume, Elke Oetjen , Hiroyoshi Hidaka, Willhart Knepel Journal of Biological Chemistry 268, 5168-5177 (1993) |
| 5 |
Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization Markus Schwaninger, Roland Blume, Elke Oetjen , Gundula Lux, Willhart Knepel Journal of Biological Chemistry 268, 23111-23115 (1993) |
| 4 |
The immunosuppressive drugs cyclosporin A and FK506 inhibit calcineurin phosphatase activity and gene transcription mediated through the cAMP-responsive element in a nonimmune cell line Markus Schwaninger, Roland Blume, Elke Oetjen , Willhart Knepel Naunyn-Schmiedeberg's Archives of Pharmacology 348, 541-545 (1993) |
1991 | |
| 3 |
Hemmung der Glucagon- und Noradrenalin-stimulierten Glucosefreisetzung durch ATP und Adenosin Elke Oetjen (= Elke Helga Ilse Oetjen) -/- Supervisor: Irmelin Probst Dissertation, Göttingen (1991) |
| 2 |
Hemmung des Transkriptionsfaktors in der pankreatischen β-Zelle - ein molekularer Mechanismus der diabetogenen Wirkung der Immunusppressiva Cyclosprin A und Tacrolimus Elke Oetjen (= Elke Helga Ilse Oetjen) Habilitationsschrift, Göttingen (1991) |
1990 | |
| 1 |
Stimulation of glucose production from glycogen by glucagon, noradrenaline and nondegradable adenosine analogs is counteracted by adenosine and ATP in cultured rat hepatocytes Elke Oetjen , Christa Schweickhardt, Kirsten Unthan-Fechner, Irmelin Probst Biochemical Journal 271, 337-344 (1990) |